Page last updated: 2024-11-03

riluzole and Retinal Neovascularization

riluzole has been researched along with Retinal Neovascularization in 1 studies

Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.

Retinal Neovascularization: Formation of new blood vessels originating from the retinal veins and extending along the inner (vitreal) surface of the retina.

Research Excerpts

ExcerptRelevanceReference
"The present study examined the effects of riluzole, a Food and Drug Administration-approved drug for amyotrophic lateral sclerosis, on VEGF-stimulated endothelial cell proliferation in culture, and on neovascularization in a rat model of retinopathy of prematurity (ROP)."7.73Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo. ( Hyun, HJ; Koh, JY; Yoo, MH; Yoon, YH, 2005)
"The present study examined the effects of riluzole, a Food and Drug Administration-approved drug for amyotrophic lateral sclerosis, on VEGF-stimulated endothelial cell proliferation in culture, and on neovascularization in a rat model of retinopathy of prematurity (ROP)."3.73Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo. ( Hyun, HJ; Koh, JY; Yoo, MH; Yoon, YH, 2005)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yoo, MH1
Hyun, HJ1
Koh, JY1
Yoon, YH1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Vascular Endothelial Growth Factor Levels in Aqueous, Vitreous and Subretinal Fluid in Patients With Retinopathy of Prematurity Stage V.[NCT00500396]Phase 415 participants (Anticipated)Interventional2007-03-31Completed
Vascular Endothelial Growth Factor Levels in Aqueous, Vitreous and Subretinal Fluid in Patients With Retinopathy of Prematurity Stage IV and V[NCT00563121]Phase 416 participants (Actual)Interventional2007-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for riluzole and Retinal Neovascularization

ArticleYear
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:12

    Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease

2005
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:12

    Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease

2005
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:12

    Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease

2005
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:12

    Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease

2005