riluzole has been researched along with Pregnancy in 5 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study examined the effects of riluzole, a Food and Drug Administration-approved drug for amyotrophic lateral sclerosis, on VEGF-stimulated endothelial cell proliferation in culture, and on neovascularization in a rat model of retinopathy of prematurity (ROP)." | 7.73 | Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo. ( Hyun, HJ; Koh, JY; Yoo, MH; Yoon, YH, 2005) |
| "The present study examined the effects of riluzole, a Food and Drug Administration-approved drug for amyotrophic lateral sclerosis, on VEGF-stimulated endothelial cell proliferation in culture, and on neovascularization in a rat model of retinopathy of prematurity (ROP)." | 3.73 | Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo. ( Hyun, HJ; Koh, JY; Yoo, MH; Yoon, YH, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erickson, JD | 1 |
| Yáñez, M | 1 |
| Galán, L | 1 |
| Matías-Guiu, J | 1 |
| Vela, A | 1 |
| Guerrero, A | 1 |
| García, AG | 1 |
| Scalco, RS | 1 |
| Vieira, MC | 1 |
| da Cunha Filho, EV | 1 |
| Lago, EG | 1 |
| da Silva, IG | 1 |
| Becker, J | 1 |
| Yoo, MH | 1 |
| Hyun, HJ | 1 |
| Koh, JY | 1 |
| Yoon, YH | 1 |
| Tyagi, A | 1 |
| Sweeney, BJ | 1 |
| Connolly, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vascular Endothelial Growth Factor Levels in Aqueous, Vitreous and Subretinal Fluid in Patients With Retinopathy of Prematurity Stage V.[NCT00500396] | Phase 4 | 15 participants (Anticipated) | Interventional | 2007-03-31 | Completed | ||
| Vascular Endothelial Growth Factor Levels in Aqueous, Vitreous and Subretinal Fluid in Patients With Retinopathy of Prematurity Stage IV and V[NCT00563121] | Phase 4 | 16 participants (Actual) | Interventional | 2007-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for riluzole and Pregnancy
| Article | Year |
|---|---|
CSF from amyotrophic lateral sclerosis patients produces glutamate independent death of rat motor brain cortical neurons: protection by resveratrol but not riluzole.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Animals; Calcium; Cell Death; Cells, Cultured; Cerebral | 2011 |
4 other studies available for riluzole and Pregnancy
| Article | Year |
|---|---|
Functional identification of activity-regulated, high-affinity glutamine transport in hippocampal neurons inhibited by riluzole.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; beta-Alanine; Calcium; Calcium Channel Blocke | 2017 |
Amyotrophic lateral sclerosis and riluzole use during pregnancy: a case report.
Topics: Adult; Amyotrophic Lateral Sclerosis; Female; Fetal Monitoring; Heart Defects, Congenital; Humans; N | 2012 |
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease | 2005 |
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease | 2005 |
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease | 2005 |
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyperoxia-induced abnormal vessel formation in vivo.
Topics: Adolescent; Animals; Animals, Newborn; Cattle; Cell Culture Techniques; Cell Proliferation; Disease | 2005 |
Amyotrophic lateral sclerosis associated with pregnancy.
Topics: Adult; Amyotrophic Lateral Sclerosis; Electromyography; Female; Humans; Magnetic Resonance Imaging; | 2001 |