riluzole has been researched along with Neuralgia in 7 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cervical spondylotic myelopathy (CSM) is the commonest cause of spinal cord impairment worldwide and despite surgical treatment, it is commonly associated with chronic neuropathic pain and neurological impairment." | 5.40 | Riluzole attenuates neuropathic pain and enhances functional recovery in a rodent model of cervical spondylotic myelopathy. ( Austin, JW; Fehlings, MG; Karadimas, SK; Moon, ES; Yu, WR, 2014) |
| "Riluzole is a benzothiazole compound with neuroprotective properties on intervention to various ion channels, including hyperpolarization-activated voltage-dependent channels." | 1.72 | Effect of Riluzole on the Expression of HCN2 in Dorsal Root Ganglion Neurons of Diabetic Neuropathic Pain Rats. ( Hao, R; Shen, FJ; Yang, JK; Zhou, DM, 2022) |
| "Chronic neuropathic pain is an important healthcare issue with significant emotional components." | 1.48 | Small conductance calcium activated potassium (SK) channel dependent and independent effects of riluzole on neuropathic pain-related amygdala activity and behaviors in rats. ( Ji, G; Neugebauer, V; Thompson, JM; Yakhnitsa, V, 2018) |
| "Neuropathic pain is becoming an intractable health threat, with its profound effect on quality of life, thus posing a major challenge to clinical therapy." | 1.43 | Effects of riluzole on P2X7R expression in the spinal cord in rat model of neuropathic pain. ( Chen, H; Ge, AQ; Jiang, K; Miao, B; Sun, L; Yan, M; Zhuang, Y, 2016) |
| "Cervical spondylotic myelopathy (CSM) is the commonest cause of spinal cord impairment worldwide and despite surgical treatment, it is commonly associated with chronic neuropathic pain and neurological impairment." | 1.40 | Riluzole attenuates neuropathic pain and enhances functional recovery in a rodent model of cervical spondylotic myelopathy. ( Austin, JW; Fehlings, MG; Karadimas, SK; Moon, ES; Yu, WR, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, DM | 1 |
| Shen, FJ | 1 |
| Hao, R | 1 |
| Yang, JK | 1 |
| Foley, P | 1 |
| Parker, RA | 1 |
| de Angelis, F | 1 |
| Connick, P | 1 |
| Chandran, S | 1 |
| Young, C | 1 |
| Weir, CJ | 1 |
| Chataway, J | 1 |
| Thompson, JM | 1 |
| Yakhnitsa, V | 1 |
| Ji, G | 1 |
| Neugebauer, V | 1 |
| Moon, ES | 1 |
| Karadimas, SK | 1 |
| Yu, WR | 1 |
| Austin, JW | 1 |
| Fehlings, MG | 1 |
| Jiang, K | 1 |
| Zhuang, Y | 1 |
| Yan, M | 1 |
| Chen, H | 1 |
| Ge, AQ | 1 |
| Sun, L | 1 |
| Miao, B | 1 |
| Hama, A | 1 |
| Sagen, J | 1 |
| Sung, B | 1 |
| Lim, G | 1 |
| Mao, J | 1 |
1 trial available for riluzole and Neuralgia
| Article | Year |
|---|---|
Efficacy of Fluoxetine, Riluzole and Amiloride in treating neuropathic pain associated with secondary progressive multiple sclerosis. Pre-specified analysis of the MS-SMART double-blind randomised placebo-controlled trial.
Topics: Adult; Amiloride; Double-Blind Method; Fluoxetine; Humans; Multiple Sclerosis; Multiple Sclerosis, C | 2022 |
6 other studies available for riluzole and Neuralgia
| Article | Year |
|---|---|
Effect of Riluzole on the Expression of HCN2 in Dorsal Root Ganglion Neurons of Diabetic Neuropathic Pain Rats.
Topics: Animals; Diabetes Mellitus; Diabetic Neuropathies; Ganglia, Spinal; Hyperpolarization-Activated Cycl | 2022 |
Small conductance calcium activated potassium (SK) channel dependent and independent effects of riluzole on neuropathic pain-related amygdala activity and behaviors in rats.
Topics: Analgesics, Non-Narcotic; Animals; Central Amygdaloid Nucleus; Disease Models, Animal; Male; Membran | 2018 |
Riluzole attenuates neuropathic pain and enhances functional recovery in a rodent model of cervical spondylotic myelopathy.
Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Gait; Hyperalgesia; Neur | 2014 |
Effects of riluzole on P2X7R expression in the spinal cord in rat model of neuropathic pain.
Topics: Animals; Constriction, Pathologic; Hyperalgesia; Male; Microglia; Neuralgia; Purinergic P2X Receptor | 2016 |
Antinociceptive effect of riluzole in rats with neuropathic spinal cord injury pain.
Topics: Animals; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal | 2011 |
Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats.
Topics: Amino Acid Transport System X-AG; Animals; Behavior, Animal; Biological Transport; Carbazoles; Const | 2003 |