Page last updated: 2024-11-03
riluzole and Necrosis
riluzole has been researched along with Necrosis in 3 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Compared with the other groups, a statistically significant difference with regard to better results for necrosis, inflammation, and apoptosis was observed in the riluzole only and combination groups." | 3.85 | Combined and individual use of pancaspase inhibitor Q-VD-OPh and NMDA receptor antagonist riluzole in experimental spinal cord injury. ( Altunrende, ME; Aydoseli, A; Can, H; Dolgun, M; Göker, B; Gömleksiz, C; Sencer, A, 2017) |
" We investigated the effects of riluzole, a neuroprotective drug that blocks glutamatergic neurotransmission, in a rabbit model of spinal cord ischemia." | 3.70 | Riluzole prevents ischemic spinal cord injury caused by aortic crossclamping. ( Heurteaux, C; Lang-Lazdunski, L; Lazdunski, M; Vaillant, N; Widmann, C, 1999) |
"Riluzole may protect the spinal cord in a setting of severe ischemia by preventing neuronal necrosis and apoptosis." | 3.70 | Ischemic spinal cord injury induced by aortic cross-clamping: prevention by riluzole. ( Desmonts, J; Heurteaux, C; Lang-Lazdunski, L; Lazdunski, M; Mantz, J; Mignon, A; Widmann, C, 2000) |
Research
Studies (3)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Can, H | 1 |
Aydoseli, A | 1 |
Gömleksiz, C | 1 |
Göker, B | 1 |
Altunrende, ME | 1 |
Dolgun, M | 1 |
Sencer, A | 1 |
Lang-Lazdunski, L | 2 |
Heurteaux, C | 2 |
Vaillant, N | 1 |
Widmann, C | 2 |
Lazdunski, M | 2 |
Mignon, A | 1 |
Mantz, J | 1 |
Desmonts, J | 1 |
Other Studies
3 other studies available for riluzole and Necrosis
Article | Year |
---|---|
Combined and individual use of pancaspase inhibitor Q-VD-OPh and NMDA receptor antagonist riluzole in experimental spinal cord injury.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Disease Models, Animal; Male; Necrosis; Neuropr | 2017 |
Riluzole prevents ischemic spinal cord injury caused by aortic crossclamping.
Topics: Animals; Aorta, Abdominal; Apoptosis; Constriction; Cytoplasm; Disease Models, Animal; DNA; DNA Frag | 1999 |
Ischemic spinal cord injury induced by aortic cross-clamping: prevention by riluzole.
Topics: Animals; Aorta, Thoracic; Apoptosis; Biomarkers; Electrophoresis, Agar Gel; Excitatory Amino Acid An | 2000 |