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riluzole and Necrosis

riluzole has been researched along with Necrosis in 3 studies

Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Compared with the other groups, a statistically significant difference with regard to better results for necrosis, inflammation, and apoptosis was observed in the riluzole only and combination groups."3.85Combined and individual use of pancaspase inhibitor Q-VD-OPh and NMDA receptor antagonist riluzole in experimental spinal cord injury. ( Altunrende, ME; Aydoseli, A; Can, H; Dolgun, M; Göker, B; Gömleksiz, C; Sencer, A, 2017)
" We investigated the effects of riluzole, a neuroprotective drug that blocks glutamatergic neurotransmission, in a rabbit model of spinal cord ischemia."3.70Riluzole prevents ischemic spinal cord injury caused by aortic crossclamping. ( Heurteaux, C; Lang-Lazdunski, L; Lazdunski, M; Vaillant, N; Widmann, C, 1999)
"Riluzole may protect the spinal cord in a setting of severe ischemia by preventing neuronal necrosis and apoptosis."3.70Ischemic spinal cord injury induced by aortic cross-clamping: prevention by riluzole. ( Desmonts, J; Heurteaux, C; Lang-Lazdunski, L; Lazdunski, M; Mantz, J; Mignon, A; Widmann, C, 2000)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Can, H1
Aydoseli, A1
Gömleksiz, C1
Göker, B1
Altunrende, ME1
Dolgun, M1
Sencer, A1
Lang-Lazdunski, L2
Heurteaux, C2
Vaillant, N1
Widmann, C2
Lazdunski, M2
Mignon, A1
Mantz, J1
Desmonts, J1

Other Studies

3 other studies available for riluzole and Necrosis

ArticleYear
Combined and individual use of pancaspase inhibitor Q-VD-OPh and NMDA receptor antagonist riluzole in experimental spinal cord injury.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2017, Volume: 23, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Disease Models, Animal; Male; Necrosis; Neuropr

2017
Riluzole prevents ischemic spinal cord injury caused by aortic crossclamping.
    The Journal of thoracic and cardiovascular surgery, 1999, Volume: 117, Issue:5

    Topics: Animals; Aorta, Abdominal; Apoptosis; Constriction; Cytoplasm; Disease Models, Animal; DNA; DNA Frag

1999
Ischemic spinal cord injury induced by aortic cross-clamping: prevention by riluzole.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2000, Volume: 18, Issue:2

    Topics: Animals; Aorta, Thoracic; Apoptosis; Biomarkers; Electrophoresis, Agar Gel; Excitatory Amino Acid An

2000
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