riluzole has been researched along with Muscle Spasticity in 6 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Cotinat, M | 1 |
| Boquet, I | 1 |
| Ursino, M | 1 |
| Brocard, C | 1 |
| Jouve, E | 1 |
| Alberti, C | 1 |
| Bensoussan, L | 1 |
| Viton, JM | 1 |
| Brocard, F | 1 |
| Blin, O | 1 |
| Lau, FS | 1 |
| Brennan, FP | 1 |
| Gardiner, MD | 1 |
| Scott, K | 1 |
| Shannon, R | 1 |
| Roche-Green, A | 1 |
| Searcy, R | 1 |
| Woolyhand, G | 1 |
| Meeks, G | 1 |
| Schuh, M | 1 |
| Kitzman, PH | 1 |
| Theiss, RD | 1 |
| Hornby, TG | 1 |
| Rymer, WZ | 1 |
| Schmit, BD | 1 |
| Rauf, J | 1 |
| Akhtar, J | 1 |
| Khealani, BA | 1 |
| Ali, L | 1 |
2 trials available for riluzole and Muscle Spasticity
| Article | Year |
|---|---|
Riluzole for treating spasticity in patients with chronic traumatic spinal cord injury: Study protocol in the phase ib/iib adaptive multicenter randomized controlled RILUSCI trial.
Topics: Adult; Bayes Theorem; Clinical Trials, Phase I as Topic; Double-Blind Method; Humans; Multicenter St | 2023 |
Riluzole decreases flexion withdrawal reflex but not voluntary ankle torque in human chronic spinal cord injury.
Topics: Adult; Analysis of Variance; Ankle; Double-Blind Method; Electric Stimulation; Electromyography; Fem | 2011 |
4 other studies available for riluzole and Muscle Spasticity
| Article | Year |
|---|---|
Multidisciplinary management of motor neurone disease.
Topics: Dyspnea; Humans; Interdisciplinary Communication; Motor Neuron Disease; Muscle Spasticity; Neuroprot | 2018 |
Pharmacologic Management Strategies in ALS #301.
Topics: Amyotrophic Lateral Sclerosis; Depression; Dyspnea; Guidelines as Topic; Humans; Muscle Spasticity; | 2016 |
Effectiveness of riluzole in suppressing spasticity in the spinal cord injured rat.
Topics: Animals; Electromyography; Female; Muscle Spasticity; Neuroprotective Agents; Rats; Rats, Sprague-Da | 2009 |
Peripheral (limb) myokymic discharges in motor neuron disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Baclofen; Deltoid Muscle; Directive | 2012 |