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riluzole and Movement Disorders

riluzole has been researched along with Movement Disorders in 5 studies

Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"Cotreatment with riluzole (4 mg/kg i."1.30Riluzole reduces incidence of abnormal movements but not striatal cell death in a primate model of progressive striatal degeneration. ( Brouillet, E; Guyot, MC; Hantraye, P; Mary, V; Palfi, S; Peschanski, M; Riche, D; Stutzmann, JM; Wahl, F, 1997)
" In addition, it was checked that this neuroprotective effect of riluzole against systemic 3-nitropropionic acid did not result from a decreased bioavailability of the neurotoxin or a direct action of riluzole on 3-nitropropionic acid-induced inhibition of succinate dehydrogenase."1.30Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats. ( Brouillet, E; Guyot, MC; Hantraye, P; Mazière, M; Palfi, S; Stutzmann, JM, 1997)
"Riluzole treatment almost completely prevented the neuronal degeneration in these brain areas."1.30Effect of riluzole on the neurological and neuropathological changes in an animal model of cardiac arrest-induced movement disorder. ( Kanthasamy, AG; Nguyen, B; Truong, DD; Yun, RJ, 1999)
"Treatment with Riluzole had no significant effect on posttraumatic lesion volume."1.29Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat. ( McIntosh, TK; Perri, BR; Smith, DH; Stutzmann, JM; Voddi, M, 1996)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (80.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Theiss, RD1
Hornby, TG1
Rymer, WZ1
Schmit, BD1
McIntosh, TK1
Smith, DH1
Voddi, M1
Perri, BR1
Stutzmann, JM3
Palfi, S2
Riche, D1
Brouillet, E2
Guyot, MC2
Mary, V1
Wahl, F1
Peschanski, M1
Hantraye, P2
Mazière, M1
Kanthasamy, AG1
Yun, RJ1
Nguyen, B1
Truong, DD1

Trials

1 trial available for riluzole and Movement Disorders

ArticleYear
Riluzole decreases flexion withdrawal reflex but not voluntary ankle torque in human chronic spinal cord injury.
    Journal of neurophysiology, 2011, Volume: 105, Issue:6

    Topics: Adult; Analysis of Variance; Ankle; Double-Blind Method; Electric Stimulation; Electromyography; Fem

2011

Other Studies

4 other studies available for riluzole and Movement Disorders

ArticleYear
Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat.
    Journal of neurotrauma, 1996, Volume: 13, Issue:12

    Topics: Animals; Body Water; Brain Edema; Brain Injuries; Cognition Disorders; Male; Movement Disorders; Neu

1996
Riluzole reduces incidence of abnormal movements but not striatal cell death in a primate model of progressive striatal degeneration.
    Experimental neurology, 1997, Volume: 146, Issue:1

    Topics: Acetylcholinesterase; Animals; Antiparkinson Agents; Apomorphine; Caudate Nucleus; Corpus Striatum;

1997
Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats.
    Neuroscience, 1997, Volume: 81, Issue:1

    Topics: Animals; Antihypertensive Agents; Corpus Striatum; Injections, Intraperitoneal; Male; Malonates; Mic

1997
Effect of riluzole on the neurological and neuropathological changes in an animal model of cardiac arrest-induced movement disorder.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Heart Arrest; Histocytochemistry; Male; Movement D

1999