riluzole has been researched along with Morphine Abuse in 2 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Morphine tolerance was complete after 8 days in the control groups but was complete in the groups treated with minocycline (120 microg/10 microL per rat) and riluzole (80 microg/10 microL per rat) on the 13th day." | 1.35 | Central administration of minocycline and riluzole prevents morphine-induced tolerance in rats. ( Charkhpour, M; Habibi-Asl, B; Hassanzadeh, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Habibi-Asl, B | 1 |
| Hassanzadeh, K | 1 |
| Charkhpour, M | 1 |
| Mao, J | 1 |
| Sung, B | 1 |
| Ji, RR | 1 |
| Lim, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Personalizing Perioperative Morphine Analgesia for Adolescents Undergoing Major Spine Surgeries[NCT01839461] | 137 participants (Actual) | Observational | 2009-07-31 | Completed | |||
| Double Blind Trial Investigating the Role of Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients[NCT03847311] | Phase 2 | 40 participants (Anticipated) | Interventional | 2021-05-03 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for riluzole and Morphine Abuse
| Article | Year |
|---|---|
Central administration of minocycline and riluzole prevents morphine-induced tolerance in rats.
Topics: Analgesics, Opioid; Animals; Anti-Bacterial Agents; Area Under Curve; Drug Tolerance; Glutamic Acid; | 2009 |
Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity.
Topics: Amino Acid Transport System X-AG; Analgesics; Animals; Behavior, Animal; Down-Regulation; Drug Admin | 2002 |
Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity.
Topics: Amino Acid Transport System X-AG; Analgesics; Animals; Behavior, Animal; Down-Regulation; Drug Admin | 2002 |
Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity.
Topics: Amino Acid Transport System X-AG; Analgesics; Animals; Behavior, Animal; Down-Regulation; Drug Admin | 2002 |
Chronic morphine induces downregulation of spinal glutamate transporters: implications in morphine tolerance and abnormal pain sensitivity.
Topics: Amino Acid Transport System X-AG; Analgesics; Animals; Behavior, Animal; Down-Regulation; Drug Admin | 2002 |