riluzole has been researched along with Liver Neoplasms in 2 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Through a drug repositioning screening, we identified and investigated the action mechanism of the Riluzole, an amyotrophic lateral sclerosis (ALS) drug, on hepatocellular carcinoma (HCC) therapy." | 7.83 | Glutamate release inhibitor, Riluzole, inhibited proliferation of human hepatocellular carcinoma cells by elevated ROS production. ( Chang, S; Jang, SJ; Kim, I; Lee, HY; Lee, SE; Park, S; Seol, HS; Singh, SR; Song, JS, 2016) |
| " This study examined the effect of riluzole on [Ca2+]i in IMR32 neuroblastoma cells using fura-2 as a Ca2+ probe." | 7.71 | Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells. ( Chang, CH; Chen, WC; Chow, CK; Jan, CR; Law, YP; Lee, KC; Lu, T; Su, W; Tang, KY; Wang, JL, 2001) |
| " Through a drug repositioning screening, we identified and investigated the action mechanism of the Riluzole, an amyotrophic lateral sclerosis (ALS) drug, on hepatocellular carcinoma (HCC) therapy." | 3.83 | Glutamate release inhibitor, Riluzole, inhibited proliferation of human hepatocellular carcinoma cells by elevated ROS production. ( Chang, S; Jang, SJ; Kim, I; Lee, HY; Lee, SE; Park, S; Seol, HS; Singh, SR; Song, JS, 2016) |
| " This study examined the effect of riluzole on [Ca2+]i in IMR32 neuroblastoma cells using fura-2 as a Ca2+ probe." | 3.71 | Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells. ( Chang, CH; Chen, WC; Chow, CK; Jan, CR; Law, YP; Lee, KC; Lu, T; Su, W; Tang, KY; Wang, JL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Seol, HS | 1 |
| Lee, SE | 1 |
| Song, JS | 1 |
| Lee, HY | 1 |
| Park, S | 1 |
| Kim, I | 1 |
| Singh, SR | 1 |
| Chang, S | 1 |
| Jang, SJ | 1 |
| Wang, JL | 1 |
| Lee, KC | 1 |
| Tang, KY | 1 |
| Lu, T | 1 |
| Chang, CH | 1 |
| Chow, CK | 1 |
| Chen, WC | 1 |
| Su, W | 1 |
| Law, YP | 1 |
| Jan, CR | 1 |
2 other studies available for riluzole and Liver Neoplasms
| Article | Year |
|---|---|
Glutamate release inhibitor, Riluzole, inhibited proliferation of human hepatocellular carcinoma cells by elevated ROS production.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Hepatocellular; | 2016 |
Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells.
Topics: Animals; Brefeldin A; Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; | 2001 |