Page last updated: 2024-11-03

riluzole and Ischemia

riluzole has been researched along with Ischemia in 5 studies

Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" Riluzole, Lidocaine and Lamotrigine were given prior to renal ischemia only (IO) or IRI."4.12Pharmacological prevention of renal ischemia-reperfusion injury in a rat model. ( Deng, Y; Li, RW; Smith, PN; Weiss, S; Yang, YL, 2022)
" We investigated the effects of riluzole, a neuroprotective drug that blocks glutamatergic neurotransmission, in a rabbit model of spinal cord ischemia."3.70Riluzole prevents ischemic spinal cord injury caused by aortic crossclamping. ( Heurteaux, C; Lang-Lazdunski, L; Lazdunski, M; Vaillant, N; Widmann, C, 1999)
" We investigated the effects of the anti-excitotoxic drugs magnesium sulfate (MgSO(4)) and riluzole in a rabbit model of spinal cord ischemia."3.70Prevention of ischemic spinal cord injury: comparative effects of magnesium sulfate and riluzole. ( Dupont, H; Heurteaux, C; Lang-Lazdunski, L; Lazdunski, M; Widmann, C, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Deng, Y1
Li, RW1
Yang, YL1
Weiss, S1
Smith, PN1
Zhu, Y1
Gao, M1
Zhou, T1
Xie, M1
Mao, A1
Feng, L1
Yao, X1
Wong, WT1
Ma, X1
Lang-Lazdunski, L2
Heurteaux, C2
Vaillant, N1
Widmann, C2
Lazdunski, M2
Miyamoto, TA1
Miyamoto, KJ1
Dupont, H1

Other Studies

5 other studies available for riluzole and Ischemia

ArticleYear
Pharmacological prevention of renal ischemia-reperfusion injury in a rat model.
    ANZ journal of surgery, 2022, Volume: 92, Issue:3

    Topics: Animals; Glutathione; Humans; Ischemia; Kidney; Lamotrigine; Lidocaine; Rats; Reperfusion Injury; Ri

2022
The TRPC5 channel regulates angiogenesis and promotes recovery from ischemic injury in mice.
    The Journal of biological chemistry, 2019, 01-04, Volume: 294, Issue:1

    Topics: Animals; Disease Models, Animal; Endothelial Cells; HEK293 Cells; Humans; Ischemia; Mice; Mice, Knoc

2019
Riluzole prevents ischemic spinal cord injury caused by aortic crossclamping.
    The Journal of thoracic and cardiovascular surgery, 1999, Volume: 117, Issue:5

    Topics: Animals; Aorta, Abdominal; Apoptosis; Constriction; Cytoplasm; Disease Models, Animal; DNA; DNA Frag

1999
A word of caution in extrapolating the riluzole spinal cord injury protective effects obtained in a rabbit model under ketamine anesthesia.
    The Journal of thoracic and cardiovascular surgery, 1999, Volume: 118, Issue:6

    Topics: Anesthetics, Dissociative; Animals; Cardiopulmonary Bypass; Disease Models, Animal; Drug Synergism;

1999
Prevention of ischemic spinal cord injury: comparative effects of magnesium sulfate and riluzole.
    Journal of vascular surgery, 2000, Volume: 32, Issue:1

    Topics: Animals; Aorta; Aorta, Thoracic; Constriction; Female; Immunohistochemistry; Ischemia; Magnesium Sul

2000