riluzole has been researched along with Glial Cell Tumors in 6 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Riluzole and memantine can be safely and effectively delivered intracranially via polymer in rat glioma models." | 7.80 | Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models. ( Blakeley, J; Brem, H; Gincel, D; Pardo, AC; Rothstein, JD; Tyler, B; Weaver, KD; Yohay, K, 2014) |
| " This study examined the effect of riluzole on [Ca2+]i in IMR32 neuroblastoma cells using fura-2 as a Ca2+ probe." | 7.71 | Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells. ( Chang, CH; Chen, WC; Chow, CK; Jan, CR; Law, YP; Lee, KC; Lu, T; Su, W; Tang, KY; Wang, JL, 2001) |
| "In the present study, we investigated the effects of mGluR1 inhibition in human glioma U87 cells using specific targeted small interfering RNA (siRNA) or selective antagonists Riluzole and BAY36-7620." | 3.81 | Anti-cancer effect of metabotropic glutamate receptor 1 inhibition in human glioma U87 cells: involvement of PI3K/Akt/mTOR pathway. ( Li, HY; Liao, YW; Liu, Q; Sang, SS; Su, J; Wang, XY; Yuan, XR; Zhang, C; Zhao, ZJ, 2015) |
| "Riluzole and memantine can be safely and effectively delivered intracranially via polymer in rat glioma models." | 3.80 | Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models. ( Blakeley, J; Brem, H; Gincel, D; Pardo, AC; Rothstein, JD; Tyler, B; Weaver, KD; Yohay, K, 2014) |
| " Finally, we investigated its effects on pilocarpine-induced seizures in rats." | 3.78 | Characterizing the effects of Eugenol on neuronal ionic currents and hyperexcitability. ( Chow, JC; Huang, CW; Tsai, JJ; Wu, SN, 2012) |
| " This study examined the effect of riluzole on [Ca2+]i in IMR32 neuroblastoma cells using fura-2 as a Ca2+ probe." | 3.71 | Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells. ( Chang, CH; Chen, WC; Chow, CK; Jan, CR; Law, YP; Lee, KC; Lu, T; Su, W; Tang, KY; Wang, JL, 2001) |
| "Riluzole is a drug approved for the treatment of amyotrophic lateral sclerosis (ALS) and may be effective for the treatment of other neurodegenerative and neuropsychiatric disorders." | 1.39 | Riluzole increases glutamate uptake by cultured C6 astroglial cells. ( Bobermin, LD; Dall'Igna, OP; Quincozes-Santos, A; Souza, DO, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dall'Igna, OP | 1 |
| Bobermin, LD | 1 |
| Souza, DO | 1 |
| Quincozes-Santos, A | 1 |
| Yohay, K | 1 |
| Tyler, B | 1 |
| Weaver, KD | 1 |
| Pardo, AC | 1 |
| Gincel, D | 1 |
| Blakeley, J | 1 |
| Brem, H | 1 |
| Rothstein, JD | 1 |
| Zhang, C | 1 |
| Yuan, XR | 1 |
| Li, HY | 1 |
| Zhao, ZJ | 1 |
| Liao, YW | 1 |
| Wang, XY | 1 |
| Su, J | 1 |
| Sang, SS | 1 |
| Liu, Q | 1 |
| Tsuchioka, M | 1 |
| Hisaoka, K | 1 |
| Yano, R | 1 |
| Shibasaki, C | 1 |
| Kajiatani, N | 1 |
| Takebayashi, M | 1 |
| Huang, CW | 1 |
| Chow, JC | 1 |
| Tsai, JJ | 1 |
| Wu, SN | 1 |
| Wang, JL | 1 |
| Lee, KC | 1 |
| Tang, KY | 1 |
| Lu, T | 1 |
| Chang, CH | 1 |
| Chow, CK | 1 |
| Chen, WC | 1 |
| Su, W | 1 |
| Law, YP | 1 |
| Jan, CR | 1 |
6 other studies available for riluzole and Glial Cell Tumors
| Article | Year |
|---|---|
Riluzole increases glutamate uptake by cultured C6 astroglial cells.
Topics: Analysis of Variance; Animals; Astrocytes; Cell Line, Tumor; Dose-Response Relationship, Drug; Excit | 2013 |
Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Disease Models, Animal; Drug Delivery Systems; Excitator | 2014 |
Anti-cancer effect of metabotropic glutamate receptor 1 inhibition in human glioma U87 cells: involvement of PI3K/Akt/mTOR pathway.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Glioma | 2015 |
Riluzole-induced glial cell line-derived neurotrophic factor production is regulated through fibroblast growth factor receptor signaling in rat C6 glioma cells.
Topics: Animals; Cell Line, Tumor; CREB-Binding Protein; Dose-Response Relationship, Drug; Drug Interactions | 2011 |
Characterizing the effects of Eugenol on neuronal ionic currents and hyperexcitability.
Topics: Action Potentials; Animals; Calcium Channels, L-Type; Cell Line, Tumor; Delayed Rectifier Potassium | 2012 |
Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells.
Topics: Animals; Brefeldin A; Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; | 2001 |