riluzole has been researched along with Encephalopathy, Toxic in 3 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Riluzole has no negative effect on oxaliplatin antiproliferative capacity in human colorectal cancer cells and on its anticancer effect in a mouse model of colorectal cancer." | 1.48 | Targeting the TREK-1 potassium channel via riluzole to eliminate the neuropathic and depressive-like effects of oxaliplatin. ( Aissouni, Y; Authier, N; Balayssac, D; Barriere, DA; Busserolles, J; Eschalier, A; Giraudet, F; Kerckhove, N; Lamoine, S; Lazdunski, M; Lolignier, S; Meleine, M; Pereira, V; Poupon, L; Prival, L; Richard, D, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poupon, L | 1 |
| Lamoine, S | 1 |
| Pereira, V | 1 |
| Barriere, DA | 1 |
| Lolignier, S | 1 |
| Giraudet, F | 1 |
| Aissouni, Y | 1 |
| Meleine, M | 1 |
| Prival, L | 1 |
| Richard, D | 1 |
| Kerckhove, N | 2 |
| Authier, N | 1 |
| Balayssac, D | 2 |
| Eschalier, A | 2 |
| Lazdunski, M | 1 |
| Busserolles, J | 2 |
| Stanbury, T | 1 |
| Pereira, B | 1 |
| Plence, V | 1 |
| Bonnetain, F | 1 |
| Krakowski, I | 1 |
| Pezet, D | 1 |
| Milane, A | 1 |
| Tortolano, L | 1 |
| Fernandez, C | 1 |
| Bensimon, G | 1 |
| Meininger, V | 1 |
| Farinotti, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness Assessment of Riluzole in the Prevention of Oxaliplatin-induced Peripheral Neuropathy: A Phase II Randomized Study by UNICANCER With the Cooperation of AFSOS[NCT03722680] | Phase 2 | 80 participants (Actual) | Interventional | 2020-10-28 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for riluzole and Encephalopathy, Toxic
| Article | Year |
|---|---|
Effectiveness assessment of riluzole in the prevention of oxaliplatin-induced peripheral neuropathy: RILUZOX-01: protocol of a randomised, parallel, controlled, double-blind and multicentre study by the UNICANCER-AFSOS Supportive Care intergroup.
Topics: Antineoplastic Agents; Double-Blind Method; Humans; Multicenter Studies as Topic; Neuroprotective Ag | 2019 |
2 other studies available for riluzole and Encephalopathy, Toxic
| Article | Year |
|---|---|
Targeting the TREK-1 potassium channel via riluzole to eliminate the neuropathic and depressive-like effects of oxaliplatin.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Depression; Humans; Male; Mice; Mice, | 2018 |
Brain and plasma riluzole pharmacokinetics: effect of minocycline combination.
Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Area Under Curve; ATP Binding Cassett | 2009 |