riluzole has been researched along with DDPAC in 4 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative disorders, related by signs of deteriorating motor and cognitive functions, and short survival." | 2.52 | Molecular basis of ALS and FTD: implications for translational studies. ( Liščić, RM, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ilieva, H | 1 |
| Maragakis, NJ | 1 |
| Liščić, RM | 1 |
| Burrell, JR | 1 |
| Halliday, GM | 1 |
| Kril, JJ | 1 |
| Ittner, LM | 1 |
| Götz, J | 1 |
| Kiernan, MC | 1 |
| Hodges, JR | 1 |
| Blasco, H | 1 |
| Patin, F | 1 |
| Andres, CR | 1 |
| Corcia, P | 1 |
| Gordon, PH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multicenter Phase I/II Clinical Trial, Randomized, Controlled With Placebo, Triple Blind to Evaluate Safety, and Indications of Efficiency of the Intravenous Administration of the Therapy With 3 Doses of MSC in Patients With ASL Moderated to Severe[NCT02290886] | Phase 1/Phase 2 | 52 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for riluzole and DDPAC
| Article | Year |
|---|---|
Motoneuron Disease: Clinical.
Topics: Amyotrophic Lateral Sclerosis; Disease Progression; Exercise Therapy; Frontotemporal Dementia; Genet | 2017 |
Molecular basis of ALS and FTD: implications for translational studies.
Topics: Amyotrophic Lateral Sclerosis; DNA-Binding Proteins; Frontotemporal Dementia; Humans; Hydroxylamines | 2015 |
The frontotemporal dementia-motor neuron disease continuum.
Topics: Activities of Daily Living; Brain; C9orf72 Protein; Cognition; DNA Methylation; DNA Repeat Expansion | 2016 |
Amyotrophic Lateral Sclerosis, 2016: existing therapies and the ongoing search for neuroprotection.
Topics: Amyotrophic Lateral Sclerosis; Biomarkers; Clinical Trials as Topic; Frontotemporal Dementia; Humans | 2016 |