riluzole has been researched along with Colorectal Neoplasms in 2 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We found that of the colorectal cancer-derived cell lines tested, HCT116 showed the highest mesenchymal profile and a high hERG1 expression." | 5.46 | The role of hERG1 ion channels in epithelial-mesenchymal transition and the capacity of riluzole to reduce cisplatin resistance in colorectal cancer cells. ( Fortunato, A, 2017) |
| "We found that of the colorectal cancer-derived cell lines tested, HCT116 showed the highest mesenchymal profile and a high hERG1 expression." | 1.46 | The role of hERG1 ion channels in epithelial-mesenchymal transition and the capacity of riluzole to reduce cisplatin resistance in colorectal cancer cells. ( Fortunato, A, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fortunato, A | 1 |
| Pillozzi, S | 1 |
| D'Amico, M | 1 |
| Bartoli, G | 1 |
| Gasparoli, L | 1 |
| Petroni, G | 1 |
| Crociani, O | 1 |
| Marzo, T | 1 |
| Guerriero, A | 1 |
| Messori, L | 1 |
| Severi, M | 1 |
| Udisti, R | 1 |
| Wulff, H | 1 |
| Chandy, KG | 1 |
| Becchetti, A | 1 |
| Arcangeli, A | 1 |
2 other studies available for riluzole and Colorectal Neoplasms
| Article | Year |
|---|---|
The role of hERG1 ion channels in epithelial-mesenchymal transition and the capacity of riluzole to reduce cisplatin resistance in colorectal cancer cells.
Topics: Animals; Anticonvulsants; Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Survival; Cisp | 2017 |
The combined activation of K
Topics: Animals; Apoptosis; Benzothiazoles; Cell Cycle; Cell Line, Tumor; Cell Survival; Cisplatin; Colorect | 2018 |