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riluzole and Cognition Disorders

riluzole has been researched along with Cognition Disorders in 7 studies

Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"In part 1, I give an update on the care of patients with amyotrophic lateral sclerosis, including ways to speed diagnosis, optimal use of riluzole, multidisciplinary teams, mechanical ventilation, gastrostomy tubes, lipid-lowering agents and symptom management."4.86Amyotrophic lateral sclerosis: current practice and future treatments. ( Bedlack, RS, 2010)
"Riluzole-treated TauP301L mice exhibited improved performance in the water radial arm maze and the Morris water maze, associated with a decrease in glutamate release and an increase in glutamate uptake in the dentate gyrus, cornu ammonis 3 (CA3), and cornu ammonis 1 (CA1) regions of the hippocampus."1.42Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression. ( Gerhardt, GA; Hickman, JE; Hunsberger, HC; Libell, EM; Reed, MN; Rudy, CC; Speer, RR; Weitzner, DS, 2015)
"Patient 2 showed persecution paranoia and motor impersistence at the age of 42."1.34Monozygotic twins suffering from Huntington's disease show different cognitive and behavioural symptoms. ( Garamendi, I; Gómez-Esteban, JC; Lezcano, E; Pérez, T; Tijero, B; Velasco, F; Zarranz, JJ, 2007)
"Treatment with Riluzole had no significant effect on posttraumatic lesion volume."1.29Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat. ( McIntosh, TK; Perri, BR; Smith, DH; Stutzmann, JM; Voddi, M, 1996)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hunsberger, HC1
Weitzner, DS1
Rudy, CC1
Hickman, JE1
Libell, EM1
Speer, RR1
Gerhardt, GA1
Reed, MN1
Whitcomb, DJ1
Molnár, E1
Nourbakhsh, B1
Nunan-Saah, J1
Maghzi, AH1
Julian, LJ1
Spain, R1
Jin, C1
Lazar, A1
Pelletier, D1
Waubant, E1
Stukovnik, V1
Zidar, J1
Podnar, S1
Repovs, G1
Bedlack, RS1
Gómez-Esteban, JC1
Lezcano, E1
Zarranz, JJ1
Velasco, F1
Garamendi, I1
Pérez, T1
Tijero, B1
McIntosh, TK1
Smith, DH1
Voddi, M1
Perri, BR1
Stutzmann, JM1

Reviews

1 review available for riluzole and Cognition Disorders

ArticleYear
Amyotrophic lateral sclerosis: current practice and future treatments.
    Current opinion in neurology, 2010, Volume: 23, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Biomarkers; Cognition Disorders; Evidence-Based Medicine; Forecasting

2010

Other Studies

6 other studies available for riluzole and Cognition Disorders

ArticleYear
Riluzole rescues glutamate alterations, cognitive deficits, and tau pathology associated with P301L tau expression.
    Journal of neurochemistry, 2015, Volume: 135, Issue:2

    Topics: Alzheimer Disease; Animals; Brain Chemistry; Cognition Disorders; Excitatory Amino Acid Antagonists;

2015
Is riluzole a new drug for Alzheimer's disease?
    Journal of neurochemistry, 2015, Volume: 135, Issue:2

    Topics: Animals; Cognition Disorders; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Neuroprotect

2015
Longitudinal associations between MRI and cognitive changes in very early MS.
    Multiple sclerosis and related disorders, 2016, Volume: 5

    Topics: Adult; Cognition Disorders; Disease Progression; Female; Humans; Longitudinal Studies; Magnetic Reso

2016
Amyotrophic lateral sclerosis patients show executive impairments on standard neuropsychological measures and an ecologically valid motor-free test of executive functions.
    Journal of clinical and experimental neuropsychology, 2010, Volume: 32, Issue:10

    Topics: Algorithms; Amyotrophic Lateral Sclerosis; Back; Cognition Disorders; Depressive Disorder; Diagnosti

2010
Monozygotic twins suffering from Huntington's disease show different cognitive and behavioural symptoms.
    European neurology, 2007, Volume: 57, Issue:1

    Topics: Adult; Anxiety; Behavioral Symptoms; Brain; Chorea; Cognition Disorders; Humans; Huntington Disease;

2007
Riluzole, a novel neuroprotective agent, attenuates both neurologic motor and cognitive dysfunction following experimental brain injury in the rat.
    Journal of neurotrauma, 1996, Volume: 13, Issue:12

    Topics: Animals; Body Water; Brain Edema; Brain Injuries; Cognition Disorders; Male; Movement Disorders; Neu

1996