riluzole has been researched along with Chorea in 5 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Chorea: Involuntary, forcible, rapid, jerky movements that may be subtle or become confluent, markedly altering normal patterns of movement. Hypotonia and pendular reflexes are often associated. Conditions which feature recurrent or persistent episodes of chorea as a primary manifestation of disease are referred to as CHOREATIC DISORDERS. Chorea is also a frequent manifestation of BASAL GANGLIA DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine the dosage-related impact of riluzole on chorea in HD." | 5.10 | Dosage effects of riluzole in Huntington's disease: a multicenter placebo-controlled study. ( , 2003) |
| "If HD chorea requires treatment, clinicians should prescribe tetrabenazine (up to 100 mg/day), amantadine (300-400 mg/day), or riluzole (200 mg/day) (Level B) for varying degrees of expected benefit." | 3.78 | Evidence-based guideline: pharmacologic treatment of chorea in Huntington disease: report of the guideline development subcommittee of the American Academy of Neurology. ( Armstrong, MJ; Miyasaki, JM, 2012) |
| "Patient 2 showed persecution paranoia and motor impersistence at the age of 42." | 1.34 | Monozygotic twins suffering from Huntington's disease show different cognitive and behavioural symptoms. ( Garamendi, I; Gómez-Esteban, JC; Lezcano, E; Pérez, T; Tijero, B; Velasco, F; Zarranz, JJ, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Armstrong, MJ | 1 |
| Miyasaki, JM | 1 |
| Gómez-Esteban, JC | 1 |
| Lezcano, E | 1 |
| Zarranz, JJ | 1 |
| Velasco, F | 1 |
| Garamendi, I | 1 |
| Pérez, T | 1 |
| Tijero, B | 1 |
| Bonelli, RM | 1 |
| Hofmann, P | 1 |
| Rosas, HD | 1 |
| Koroshetz, WJ | 1 |
| Jenkins, BG | 1 |
| Chen, YI | 1 |
| Hayden, DL | 1 |
| Beal, MF | 1 |
| Cudkowicz, ME | 1 |
1 review available for riluzole and Chorea
| Article | Year |
|---|---|
A systematic review of the treatment studies in Huntington's disease since 1990.
Topics: Amantadine; Antipsychotic Agents; Chorea; Depression; Humans; Huntington Disease; Neuroprotective Ag | 2007 |
2 trials available for riluzole and Chorea
| Article | Year |
|---|---|
Dosage effects of riluzole in Huntington's disease: a multicenter placebo-controlled study.
Topics: Chorea; Dose-Response Relationship, Drug; Double-Blind Method; Excitatory Amino Acid Antagonists; Fe | 2003 |
Riluzole therapy in Huntington's disease (HD).
Topics: Adult; Basal Ganglia; Chorea; Excitatory Amino Acid Antagonists; Female; Humans; Huntington Disease; | 1999 |
2 other studies available for riluzole and Chorea
| Article | Year |
|---|---|
Evidence-based guideline: pharmacologic treatment of chorea in Huntington disease: report of the guideline development subcommittee of the American Academy of Neurology.
Topics: Adult; Amantadine; Anticonvulsants; Chorea; Evidence-Based Medicine; Humans; Huntington Disease; Ril | 2012 |
Monozygotic twins suffering from Huntington's disease show different cognitive and behavioural symptoms.
Topics: Adult; Anxiety; Behavioral Symptoms; Brain; Chorea; Cognition Disorders; Humans; Huntington Disease; | 2007 |