riluzole has been researched along with Cancer of Skin in 4 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Earlier, we demonstrated the accumulation of phosphorylated histone H2AX (γH2AX), a marker for DNA damage when mGluR1-expressing melanoma cells were treated with a functional inhibitor, riluzole." | 7.96 | Nonhomologous end-joining repair is likely involved in the repair of double-stranded DNA breaks induced by riluzole in melanoma cells. ( Cerchio, R; Chen, S; Foo, TK; Marinaro, C; Xia, B, 2020) |
| " Earlier, we demonstrated the accumulation of phosphorylated histone H2AX (γH2AX), a marker for DNA damage when mGluR1-expressing melanoma cells were treated with a functional inhibitor, riluzole." | 3.96 | Nonhomologous end-joining repair is likely involved in the repair of double-stranded DNA breaks induced by riluzole in melanoma cells. ( Cerchio, R; Chen, S; Foo, TK; Marinaro, C; Xia, B, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cerchio, R | 1 |
| Marinaro, C | 1 |
| Foo, TK | 1 |
| Xia, B | 1 |
| Chen, S | 3 |
| Wen, Y | 1 |
| Li, J | 1 |
| Koo, J | 1 |
| Shin, SS | 2 |
| Lin, Y | 1 |
| Jeong, BS | 1 |
| Mehnert, JM | 1 |
| Cohen-Sola, KA | 1 |
| Goydos, JS | 3 |
| Le, MN | 1 |
| Chan, JL | 1 |
| Rosenberg, SA | 1 |
| Nabatian, AS | 1 |
| Merrigan, KT | 1 |
| Cohen-Solal, KA | 1 |
| Namkoong, J | 1 |
| Lee, HJ | 1 |
| Marín, YE | 1 |
| Wall, BA | 1 |
4 other studies available for riluzole and Cancer of Skin
| Article | Year |
|---|---|
Nonhomologous end-joining repair is likely involved in the repair of double-stranded DNA breaks induced by riluzole in melanoma cells.
Topics: Cell Line, Tumor; DNA Breaks, Double-Stranded; DNA End-Joining Repair; DNA Repair; Humans; Melanoma; | 2020 |
Activation of the glutamate receptor GRM1 enhances angiogenic signaling to drive melanoma progression.
Topics: Angiogenesis Inhibitors; Animals; Cell Movement; Heterocyclic Compounds, 3-Ring; Humans; Hypoxia-Ind | 2014 |
The glutamate release inhibitor Riluzole decreases migration, invasion, and proliferation of melanoma cells.
Topics: Cell Division; Cell Line, Tumor; Cell Movement; Excitatory Amino Acid Antagonists; Extracellular Sig | 2010 |
Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Drug Evaluation, Preclinical; Glutami | 2007 |