riluzole has been researched along with Behavior Disorders in 5 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We evaluated the evidence from randomized controlled trials (RCTs) regarding the use of the glutamatergic drug riluzole in mental illnesses; and conducted preliminary meta-analyses of its effectiveness in treating obsessive-compulsive disorder (OCD) and depression." | 5.01 | Efficacy and tolerability of riluzole in psychiatric disorders: A systematic review and preliminary meta-analysis. ( Amelsvoort, TV; de Boer, JN; Hirdes, M; McAlonan, GM; Vingerhoets, C; Zinkstok, JR, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Boer, JN | 1 |
| Vingerhoets, C | 1 |
| Hirdes, M | 1 |
| McAlonan, GM | 1 |
| Amelsvoort, TV | 1 |
| Zinkstok, JR | 1 |
| Zarate, CA | 1 |
| Manji, HK | 1 |
| Grant, P | 1 |
| Song, JY | 1 |
| Swedo, SE | 1 |
| Risterucci, C | 1 |
| Coccurello, R | 1 |
| Banasr, M | 1 |
| Stutzmann, JM | 1 |
| Amalric, M | 1 |
| Nieoullon, A | 1 |
| Howland, RH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dextromethorphan as an Augmentation Agent in Treatment-resistant Schizophrenia: A Randomized, Group Sequential Adaptive Design, Controlled Clinical Trial[NCT05944510] | Phase 4 | 72 participants (Anticipated) | Interventional | 2023-08-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for riluzole and Behavior Disorders
| Article | Year |
|---|---|
Efficacy and tolerability of riluzole in psychiatric disorders: A systematic review and preliminary meta-analysis.
Topics: Adult; Autistic Disorder; Depressive Disorder; Female; Humans; Male; Mental Disorders; Neuroprotecti | 2019 |
Riluzole in psychiatry: a systematic review of the literature.
Topics: Animals; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Interactions; Female; Huma | 2008 |
Review of the use of the glutamate antagonist riluzole in psychiatric disorders and a description of recent use in childhood obsessive-compulsive disorder.
Topics: Adult; Age Factors; Animals; Child; Clinical Trials as Topic; Excitatory Amino Acid Antagonists; Hum | 2010 |
Glutamate-modulating drugs & the treatment of mental disorders.
Topics: Acamprosate; Amantadine; Cycloserine; Glutamic Acid; Humans; Ketamine; Lamotrigine; Memantine; Menta | 2007 |
1 other study available for riluzole and Behavior Disorders
| Article | Year |
|---|---|
The metabotropic glutamate receptor subtype 5 antagonist MPEP and the Na+ channel blocker riluzole show different neuroprotective profiles in reversing behavioral deficits induced by excitotoxic prefrontal cortex lesions.
Topics: Animals; Brain Injuries; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Ibotenic | 2006 |