riluzole has been researched along with Autism Spectrum Disorder in 2 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Riluzole is a glutamatergic modulator of particular interest in autism spectrum disorder (ASD)." | 9.27 | A Randomized Placebo-Controlled Cross-Over Pilot Study of Riluzole for Drug-Refractory Irritability in Autism Spectrum Disorder. ( Adams, R; Bantel, AP; Erickson, CA; Hong, M; Horn, PS; Pedapati, EV; Shaffer, RC; Tessier, CR; Wink, LK, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ajram, LA | 1 |
| Horder, J | 1 |
| Mendez, MA | 1 |
| Galanopoulos, A | 1 |
| Brennan, LP | 1 |
| Wichers, RH | 1 |
| Robertson, DM | 1 |
| Murphy, CM | 1 |
| Zinkstok, J | 1 |
| Ivin, G | 1 |
| Heasman, M | 1 |
| Meek, D | 1 |
| Tricklebank, MD | 1 |
| Barker, GJ | 1 |
| Lythgoe, DJ | 1 |
| Edden, RAE | 1 |
| Williams, SC | 1 |
| Murphy, DGM | 1 |
| McAlonan, GM | 1 |
| Wink, LK | 1 |
| Adams, R | 1 |
| Horn, PS | 1 |
| Tessier, CR | 1 |
| Bantel, AP | 1 |
| Hong, M | 1 |
| Shaffer, RC | 1 |
| Pedapati, EV | 1 |
| Erickson, CA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Pilot Study of Riluzole for Drug-Refractory Irritability in Autism Spectrum Disorders[NCT02081027] | Early Phase 1 | 8 participants (Actual) | Interventional | 2013-09-19 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for riluzole and Autism Spectrum Disorder
| Article | Year |
|---|---|
A Randomized Placebo-Controlled Cross-Over Pilot Study of Riluzole for Drug-Refractory Irritability in Autism Spectrum Disorder.
Topics: Adolescent; Adult; Autism Spectrum Disorder; Child; Cross-Over Studies; Double-Blind Method; Excitat | 2018 |
1 other study available for riluzole and Autism Spectrum Disorder
| Article | Year |
|---|---|
Shifting brain inhibitory balance and connectivity of the prefrontal cortex of adults with autism spectrum disorder.
Topics: Adult; Autism Spectrum Disorder; Brain; Brain Mapping; Excitatory Amino Acid Antagonists; Functional | 2017 |