riluzole has been researched along with Age-Related Memory Disorders in 3 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The profile of inflammation-related genes and proteins associated with normal aging, or chronic neuroinflammation experimentally-induced via a four-week LPS infusion into the IV(th) ventricle, were correlated with performance in the Morris water maze following treatment with Riluzole, a drug that can enhance glutamate clearance by increasing GLT1 expression." | 3.79 | Riluzole partially rescues age-associated, but not LPS-induced, loss of glutamate transporters and spatial memory. ( Bardou, I; Brothers, HM; Corona, AW; Fenn, AM; Godbout, JP; Hopp, SC; Kaercher, RM; Wenk, GL, 2013) |
| "Treatment with riluzole restored glutamate regulation and rescued memory deficits in the TauP301L model." | 1.43 | Riluzole rescues alterations in rapid glutamate transients in the hippocampus of rTg4510 mice. ( Hickman, JE; Hunsberger, HC; Reed, MN, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brothers, HM | 1 |
| Bardou, I | 1 |
| Hopp, SC | 1 |
| Kaercher, RM | 1 |
| Corona, AW | 1 |
| Fenn, AM | 1 |
| Godbout, JP | 1 |
| Wenk, GL | 1 |
| Sasaki-Hamada, S | 1 |
| Sacai, H | 1 |
| Sugiyama, A | 1 |
| Iijima, T | 1 |
| Saitoh, A | 1 |
| Inagaki, M | 1 |
| Yamada, M | 1 |
| Oka, J | 1 |
| Hunsberger, HC | 1 |
| Hickman, JE | 1 |
| Reed, MN | 1 |
3 other studies available for riluzole and Age-Related Memory Disorders
| Article | Year |
|---|---|
Riluzole partially rescues age-associated, but not LPS-induced, loss of glutamate transporters and spatial memory.
Topics: Aging; Animals; Glutamate Plasma Membrane Transport Proteins; Hippocampus; Lipopolysaccharides; Maze | 2013 |
Riluzole does not affect hippocampal synaptic plasticity and spatial memory, which are impaired by diazepam in rats.
Topics: Amnesia; Animals; Anti-Anxiety Agents; Diazepam; Hippocampus; Male; Memory; Memory Disorders; Neuron | 2013 |
Riluzole rescues alterations in rapid glutamate transients in the hippocampus of rTg4510 mice.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Glutamic Acid; Hippocampus; Memory Disorders; Mi | 2016 |