riluzole has been researched along with Adiadochokinesis in 6 studies
Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pleiotropic effects of riluzole may antagonize common mechanisms underlying chronic cerebellar ataxia, a debilitating and untreatable consequence of various diseases." | 9.14 | Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial. ( Cannoni, S; Frontali, M; Pontieri, FE; Ristori, G; Romano, S; Salvetti, M; Spadaro, M; Vanacore, N; Visconti, A, 2010) |
| "The pleiotropic effects of riluzole may antagonize common mechanisms underlying chronic cerebellar ataxia, a debilitating and untreatable consequence of various diseases." | 5.14 | Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial. ( Cannoni, S; Frontali, M; Pontieri, FE; Ristori, G; Romano, S; Salvetti, M; Spadaro, M; Vanacore, N; Visconti, A, 2010) |
| " Here, the in vivo neuroprotective effect of riluzole on the intrinsic activity of Purkinje cells (PCs) in a rat model of cerebellar ataxia induced by 3-acetylpyridine (3-AP) was studied." | 3.75 | Co-treatment with riluzole, a neuroprotective drug, ameliorates the 3-acetylpyridine-induced neurotoxicity in cerebellar Purkinje neurones of rats: behavioural and electrophysiological evidence. ( Behzadi, G; Fathollahi, Y; Goudarzi, I; Hajizadeh, S; Janahmadi, M; Kaffashian, MR, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weissfeld, T | 1 |
| Ratliff, J | 1 |
| Saute, JAM | 1 |
| Jardim, LB | 1 |
| Brandsma, R | 1 |
| Kremer, HPH | 1 |
| Sival, DA | 1 |
| Romano, S | 2 |
| Coarelli, G | 1 |
| Vanacore, N | 2 |
| Salvetti, M | 2 |
| Ristori, G | 2 |
| Janahmadi, M | 1 |
| Goudarzi, I | 1 |
| Kaffashian, MR | 1 |
| Behzadi, G | 1 |
| Fathollahi, Y | 1 |
| Hajizadeh, S | 1 |
| Visconti, A | 1 |
| Cannoni, S | 1 |
| Spadaro, M | 1 |
| Frontali, M | 1 |
| Pontieri, FE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Riluzole in Hereditary Cerebellar Ataxia: a Randomized Double-blind Placebo-controlled Trial.[NCT01104649] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for riluzole and Adiadochokinesis
| Article | Year |
|---|---|
Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial.
Topics: Adult; Aged; Cerebellar Ataxia; Confidence Intervals; Double-Blind Method; Female; Follow-Up Studies | 2010 |
5 other studies available for riluzole and Adiadochokinesis
| Article | Year |
|---|---|
Cerebrotendinous Xanthomatosis ataxia responsive to CDCA and Riluzole.
Topics: Cerebellar Ataxia; Chenodeoxycholic Acid; Cholestanetriol 26-Monooxygenase; Female; Humans; Middle A | 2018 |
Riluzole in patients with hereditary cerebellar ataxia.
Topics: Cerebellar Ataxia; Humans; Riluzole | 2016 |
Riluzole in patients with hereditary cerebellar ataxia.
Topics: Cerebellar Ataxia; Humans; Riluzole | 2016 |
Riluzole in patients with hereditary cerebellar ataxia - Authors' reply.
Topics: Cerebellar Ataxia; Friedreich Ataxia; Humans; Riluzole | 2016 |
Co-treatment with riluzole, a neuroprotective drug, ameliorates the 3-acetylpyridine-induced neurotoxicity in cerebellar Purkinje neurones of rats: behavioural and electrophysiological evidence.
Topics: Action Potentials; Animals; Cerebellar Ataxia; Cerebellum; Drug Interactions; Male; Motor Activity; | 2009 |