Page last updated: 2024-11-03

riluzole and Adiadochokinesis

riluzole has been researched along with Adiadochokinesis in 6 studies

Riluzole: A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.

Research Excerpts

ExcerptRelevanceReference
"The pleiotropic effects of riluzole may antagonize common mechanisms underlying chronic cerebellar ataxia, a debilitating and untreatable consequence of various diseases."9.14Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial. ( Cannoni, S; Frontali, M; Pontieri, FE; Ristori, G; Romano, S; Salvetti, M; Spadaro, M; Vanacore, N; Visconti, A, 2010)
"The pleiotropic effects of riluzole may antagonize common mechanisms underlying chronic cerebellar ataxia, a debilitating and untreatable consequence of various diseases."5.14Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial. ( Cannoni, S; Frontali, M; Pontieri, FE; Ristori, G; Romano, S; Salvetti, M; Spadaro, M; Vanacore, N; Visconti, A, 2010)
" Here, the in vivo neuroprotective effect of riluzole on the intrinsic activity of Purkinje cells (PCs) in a rat model of cerebellar ataxia induced by 3-acetylpyridine (3-AP) was studied."3.75Co-treatment with riluzole, a neuroprotective drug, ameliorates the 3-acetylpyridine-induced neurotoxicity in cerebellar Purkinje neurones of rats: behavioural and electrophysiological evidence. ( Behzadi, G; Fathollahi, Y; Goudarzi, I; Hajizadeh, S; Janahmadi, M; Kaffashian, MR, 2009)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weissfeld, T1
Ratliff, J1
Saute, JAM1
Jardim, LB1
Brandsma, R1
Kremer, HPH1
Sival, DA1
Romano, S2
Coarelli, G1
Vanacore, N2
Salvetti, M2
Ristori, G2
Janahmadi, M1
Goudarzi, I1
Kaffashian, MR1
Behzadi, G1
Fathollahi, Y1
Hajizadeh, S1
Visconti, A1
Cannoni, S1
Spadaro, M1
Frontali, M1
Pontieri, FE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Riluzole in Hereditary Cerebellar Ataxia: a Randomized Double-blind Placebo-controlled Trial.[NCT01104649]Phase 2/Phase 360 participants (Actual)Interventional2010-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for riluzole and Adiadochokinesis

ArticleYear
Riluzole in cerebellar ataxia: a randomized, double-blind, placebo-controlled pilot trial.
    Neurology, 2010, Mar-09, Volume: 74, Issue:10

    Topics: Adult; Aged; Cerebellar Ataxia; Confidence Intervals; Double-Blind Method; Female; Follow-Up Studies

2010

Other Studies

5 other studies available for riluzole and Adiadochokinesis

ArticleYear
Cerebrotendinous Xanthomatosis ataxia responsive to CDCA and Riluzole.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2018, Volume: 53

    Topics: Cerebellar Ataxia; Chenodeoxycholic Acid; Cholestanetriol 26-Monooxygenase; Female; Humans; Middle A

2018
Riluzole in patients with hereditary cerebellar ataxia.
    The Lancet. Neurology, 2016, Volume: 15, Issue:8

    Topics: Cerebellar Ataxia; Humans; Riluzole

2016
Riluzole in patients with hereditary cerebellar ataxia.
    The Lancet. Neurology, 2016, Volume: 15, Issue:8

    Topics: Cerebellar Ataxia; Humans; Riluzole

2016
Riluzole in patients with hereditary cerebellar ataxia - Authors' reply.
    The Lancet. Neurology, 2016, Volume: 15, Issue:8

    Topics: Cerebellar Ataxia; Friedreich Ataxia; Humans; Riluzole

2016
Co-treatment with riluzole, a neuroprotective drug, ameliorates the 3-acetylpyridine-induced neurotoxicity in cerebellar Purkinje neurones of rats: behavioural and electrophysiological evidence.
    Neurotoxicology, 2009, Volume: 30, Issue:3

    Topics: Action Potentials; Animals; Cerebellar Ataxia; Cerebellum; Drug Interactions; Male; Motor Activity;

2009