rifampin and X-Linked-Combined-Immunodeficiency-Diseases

Mycobacterium bovis could infect patients with immunodeficiency or immunosuppressive conditions via Bacillus Calmette-Guérin (BCG) vaccination. Tuberculosis-related hemophagocytic syndrome (HPS) is reported, but not HPS caused by Mycobacterium bovis in children.. A boy with X-SCID was diagnosed with M. bovis-associated HPS, emphasizing that X-SCID should be considered when M. bovis is detected in a male infant with low lymphocyte counts.

Topics: Antibiotics, Antitubercular; High-Throughput Nucleotide Sequencing; Humans; Infant; Interleukin Receptor Common gamma Subunit; Isoniazid; Lymphohistiocytosis, Hemophagocytic; Male; Mutation; Mycobacterium bovis; Mycobacterium tuberculosis; Patient Discharge; Polymerase Chain Reaction; Pyrazinamide; Rifampin; Treatment Outcome; Tuberculosis; X-Linked Combined Immunodeficiency Diseases