rifampin and Virus-Diseases

Topics: Amantadine; Animals; Benzimidazoles; Chickenpox; Cytarabine; gamma-Globulins; Hepatitis, Viral, Human; Herpes Simplex; Herpes Zoster; Humans; Idoxuridine; Inosine Pranobex; Interferons; Measles; Mumps; Phosphonoacetic Acid; Ribavirin; Rifampin; Rubella; Vaccination; Vaccinia virus; Vidarabine; Virus Diseases

Topics: Animals; Anti-Bacterial Agents; Chick Embryo; Chlamydiaceae; Conjunctivitis, Inclusion; DNA Viruses; Fluorescent Antibody Technique; Hepatitis A; Hepatitis B Antigens; Humans; Immunologic Techniques; Keratitis, Dendritic; Meningitis, Viral; Methods; Microscopy, Electron; Rabbits; Recurrence; Rickettsia Infections; Rifampin; RNA Viruses; Sulfonamides; Trachoma; Virus Diseases

Topics: Amantadine; Anti-Inflammatory Agents; Antimetabolites; Antiviral Agents; Chemical Phenomena; Chemistry; Herpesviridae Infections; Humans; Idoxuridine; Immunosuppression Therapy; Influenza, Human; Interferons; Isoquinolines; Oxolinic Acid; Respiratory Tract Infections; Rifampin; Smallpox; Thiosemicarbazones; Virus Diseases

Topics: Amantadine; Animals; Antiviral Agents; Benzimidazoles; Culture Techniques; Cytarabine; DNA Nucleotidyltransferases; DNA Replication; Herpesviridae Infections; Humans; Idoxuridine; Infant; Influenza, Human; Interferons; Mice; Phenanthridines; Poliomyelitis; Protein Binding; Rabbits; Rifampin; RNA, Viral; Smallpox; Templates, Genetic; Thiosemicarbazones; Viral Proteins; Virus Diseases; Virus Replication

Topics: Amantadine; Anti-Bacterial Agents; Antiviral Agents; Binding Sites; Gastroenteritis; Herpesviridae Infections; Humans; Idoxuridine; Influenza, Human; Interferons; Poxviridae Infections; Respiratory Tract Infections; Rifampin; Steroids; Thiosemicarbazones; Virus Diseases; Virus Replication

Topics: Amantadine; Animals; Antiviral Agents; Chick Embryo; Cytarabine; Fluorouracil; Guanidines; Haplorhini; Humans; Idoxuridine; Interferons; Nucleosides; Receptors, Drug; Rifampin; RNA, Transfer; RNA, Viral; Uracil; Viral Proteins; Virus Diseases; Viruses

Topics: Acute Disease; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aerosols; Asthma; Bronchitis; Chromones; Chronic Disease; Ethambutol; Humans; Mycoplasma Infections; Respiratory Insufficiency; Respiratory Tract Diseases; Respiratory Tract Infections; Rifampin; Tuberculosis; Tuberculosis, Pulmonary; Virus Diseases

Osteomyelitis due to Mycobacterium bovis Bacille Calmette-Guerin (BCG) often develops in patients with interferon-γ receptor 1 (IFNγR1) deficiency. In these patients, susceptibility appears to be caused by impaired interleukin-12- and IFNγ-mediated immunity. Here we report the case of a one-year-old girl with dominant partial IFNγR1 deficiency who suffered from lymphadenitis and multiple sites of osteomyelitis due to BCG infection. She was allergic to isoniazid and rifampicin--the prescribed standard treatment--and required prior desensitization therapy. She was subsequently treated with these drugs, but her symptoms did not improve. IFNγ therapy was added to the antitubercular therapy, increasing the serum level of IFNγ and leading to the resolution of the lymphadenitis and osteomyelitis. In conclusion, high dose IFNγ therapy in combination with antitubercular drugs led to resolution of BCG infection in a patient with dominant partial IFNγ deficiency.

Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Gene Expression; Humans; Infant; Interferon-gamma; Interleukin-12; Isoniazid; Mycobacterium bovis; Osteomyelitis; Receptors, Interferon; Rifampin; Tuberculosis, Lymph Node; Virus Diseases

New antiviral compounds are being tested constantly and may be of considerable value with increasing availability. More than 200 analogues of purines and pyrimidines have been found to inhibit DNA and RNA viruses. Adenine arabinoside is most effective against disseminated herpes simplex virus and disseminated herpes zoster. Idoxuridine is useful in treatment of herpetic keratitis. Interferon still is in the experimental stage, and, because of its short half-life and high cost, it probably will not be released in the near future. Amantadine appears to be useful in prevention of A2 influenza, but its value against swine flu has not been established. Methisazone is effective in prevention of smallpox and in the treatment of complications of vaccinia.

Topics: Adult; Amantadine; Antiviral Agents; Child; Humans; Idoxuridine; Interferons; Rifampin; Thiosemicarbazones; Virus Diseases; Virus Replication

Topics: Acridines; Adenine; Amantadine; Amino Alcohols; Antiviral Agents; Arabinose; Benzoates; Coloring Agents; Cytarabine; Dimethylamines; Drug Combinations; Herpes Simplex; Humans; Idoxuridine; Indoles; Inosine; Interferons; Light; Nucleosides; Phenazines; Rifampin; Simplexvirus; Thiosemicarbazones; Virus Diseases; Virus Replication

Topics: Adult; Burkitt Lymphoma; Child; Cytarabine; Encephalitis; Female; Herpes Simplex; Herpesvirus 4, Human; Humans; Infectious Mononucleosis; Male; Rifampin; Virus Diseases

Topics: Amantadine; Coxsackievirus Infections; Cytarabine; Drug Therapy; Echovirus Infections; Humans; Idoxuridine; Interferons; Keratitis, Dendritic; Rifampin; Thiosemicarbazones; Virus Diseases

Topics: Drug Interactions; Humans; Meningococcal Infections; Microbial Sensitivity Tests; Rifampin; Tuberculosis, Pulmonary; Virus Diseases

Topics: Antiviral Agents; Brain; Humans; Interferons; Leukoencephalopathy, Progressive Multifocal; Neoplasms; Oncogenic Viruses; Papillomaviridae; Polyomaviridae; Rifampin; Streptovaricin; Virus Diseases

Topics: Antiviral Agents; Binding Sites; DNA Viruses; Humans; Rifampin; RNA Nucleotidyltransferases; RNA Viruses; Virus Diseases

Topics: Animals; Avian Sarcoma Viruses; Humans; Poxviridae; Rifampin; Vaccinia virus; Virus Diseases; Viruses

Topics: Antiviral Agents; Humans; Rifampin; Virus Diseases

Topics: Animals; Antiviral Agents; Cricetinae; Depression, Chemical; DNA Viruses; Hemagglutination Inhibition Tests; Liver; Rifampin; Virus Diseases

Topics: Antineoplastic Agents; Cytopathogenic Effect, Viral; Enzyme Induction; Feedback; Infections; Lysogeny; Neoplasms; Nucleic Acids; Penicillins; Rickettsia; Rifampin; Tetracycline; Virus Diseases