rifampin and Uveal-Diseases

rifampin has been researched along with Uveal-Diseases* in 1 studies

Other Studies

1 other study(ies) available for rifampin and Uveal-Diseases

ArticleYear
Corneal penetration of rifampin.
    American journal of ophthalmology, 1977, Volume: 83, Issue:6

    We tested the corneal penetration of rifampin in four vehicles: dimethylsulfoxide, polyethylene glycol, an ocular lubricant, and as rifampin ointment. We measured drug concentrations in the aqueous humor in rabbits after topical instillation of 1 and 2.5% rifampin according to two dosage schedules. Drug concentrations in the aqueous humor were bactericidal to Mycobacterium leprae. Since leprosy of the cornea, iris, and ciliary body may develop despite standard systemic bacteriostatic treatment, treatment of leprotic involvement of the anterior eye may be enhanced by intensive topical application of rifampin.

    Topics: Administration, Topical; Animals; Aqueous Humor; Chlorobutanol; Ciliary Body; Cornea; Dimethyl Sulfoxide; Drug Administration Schedule; Drug Combinations; Iris; Keratitis; Lanolin; Leprosy; Mineral Oil; Mycobacterium leprae; Ointments; Petrolatum; Pharmaceutical Vehicles; Polyethylene Glycols; Rabbits; Rifampin; Uveal Diseases

1977