rifampin and Sarcoma

rifampin has been researched along with Sarcoma* in 2 studies

Other Studies

2 other study(ies) available for rifampin and Sarcoma

ArticleYear
The specificity of dimethylbenzylrifampicin as an inhibitor of viral induced transformation.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:7

    The effect of 2',6'-dimethyl-N(4')-benzyl-N(4')- [desmethyl]rifampicin on viral transformation induced by two unrelated oncogenic viruses was compared. Transformation of Balb/3T3 cells by the small, DNA-containing papova virus simian virus 40 was completely normal under conditions where transformation by the large, RNA-containing oncornavirus murine sarcoma virus was inhibited more than 150-fold. For these experiments a resistant variant of Balb/3T3 was selected that grows well in high concentrations of the drug, is not dependent on the drug for growth, and is probably not blocked at the level of drug uptake. These data show that dimethyl-benzylrifampicin specifically inhibits oncornavirus-induced transformation rather than nonspecifically inhibiting cellular growth or transformation.

    Topics: Animals; Benzyl Compounds; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Drug Resistance; Fibroblasts; Gammaretrovirus; Mice; Mice, Inbred BALB C; Oncogenic Viruses; Rifampin; Sarcoma; Simian virus 40

1974
Effect of polyriboinosinic-polyribocytidylic acid on the metabolism and viability of cells in vitro.
    Journal of the National Cancer Institute, 1972, Volume: 49, Issue:3

    Topics: Amnion; Animals; Cell Line; Cells, Cultured; Conjunctiva; DNA; DNA, Neoplasm; HeLa Cells; Humans; L Cells; Leucine; Leukocytes; Lymphocytes; Mice; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Poly I-C; Protein Biosynthesis; Rifampin; RNA; RNA, Neoplasm; Sarcoma; Thymidine; Tritium; Uridine

1972