rifampin has been researched along with Rhabdomyolysis* in 2 studies
1 review(s) available for rifampin and Rhabdomyolysis
| Article | Year |
|---|---|
Pathological evidence of rhabdomyolysis-induced acute tubulointerstitial nephritis accompanying Legionella pneumophila pneumonia.
A case of Legionella pneumophila pneumonia with rhabdomyolysis-induced acute tubulointerstitial nephritis (ATIN) and prolonged renal dysfunction is presented. The patient was a 54-year-old man, admitted with high-grade fever, ataxia and muscle dysfunction; chest roentgenogram showed multilobular infiltrations. L pneumophila was detected in his sputum and urine, by PCR and by culture, and L pneumophila pneumonia was diagnosed. Despite antimicrobial treatment, he developed renal failure and rhabdomyolysis. Renal biopsy showed the presence of myoglobin casts that occluded the distal tubuli and tubulointerstitial nephritis, leading to the diagnosis of rhabdomyolysis-induced ATIN. Renal function subsequently normalised, and he was discharged. This is believed to be the first pathological evidence of involvement of rhabdomyolysis in legionellosis-associated ATIN. Topics: Anti-Bacterial Agents; Azithromycin; Ciprofloxacin; Humans; Kidney; Legionella pneumophila; Legionnaires' Disease; Male; Middle Aged; Nephritis, Interstitial; Rhabdomyolysis; Rifampin | 2008 |
1 other study(ies) available for rifampin and Rhabdomyolysis
| Article | Year |
|---|---|
From a fish tank injury to hospital haemodialysis: the serious consequences of drug interactions.
We present the case of a 68-year-old man admitted to hospital with severe acute kidney injury secondary to statin-induced rhabdomyolysis. Five weeks previously, the patient started a course of clarithromycin for infection of a finger wound with Mycobacterium marinum. His current medications included simvastatin, which he continued along with clarithromycin. The severity of the acute kidney injury necessitated initial continuous venovenous haemofiltration followed by 12 haemodialysis sessions before a spontaneous improvement in renal function occurred. Statins are widely prescribed and we report this case to encourage increased vigilance in avoiding drug interactions known to increase the risk of statin-induced myopathy, including macrolide antibiotics, calcium channel antagonists and amiodarone. The authors would also like to highlight recent guidance on atorvastatin as the statin of choice in patients with chronic kidney disease, and of the need for dose adjustment in those with an estimated glomerular filtration rate less than 30 mLs/min/1.73 m². Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Clarithromycin; Drug Interactions; Ethambutol; Finger Injuries; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mycobacterium Infections, Nontuberculous; Renal Dialysis; Rhabdomyolysis; Rifampin; Simvastatin | 2015 |