rifampin and Polycystic-Kidney-Diseases

A 49-year-old man with a medical history of polycystic kidney disease was presented to the emergency department with fever and left flank pain. Abdominal examination revealed an enlarged and painful left kidney. The C-reactive protein level was significantly high and the magnetic resonance imaging revealed areas of abnormal intensity and fluid-fluid levels in renal cysts. Brucella abortus was yielded from both blood and cyst fluid culture. Standard therapy (rifampicin plus doxycycline) of brucellosis was started, but the clinical and laboratory signs subsided after the addition of ciprofloxacin. There was no need for aspiration of infected cyst fluid. Hereby, according to the medical database search, we report that the first renal cyst infection caused by B. abortus was successfully treated with triple antibiotic therapy.

Topics: Brucella abortus; Brucellosis; Ciprofloxacin; Doxycycline; Drug Therapy, Combination; Emergency Service, Hospital; Flank Pain; Follow-Up Studies; Humans; Infusions, Intravenous; Magnetic Resonance Imaging; Middle Aged; Polycystic Kidney Diseases; Rifampin; Treatment Outcome