rifampin and Ovarian-Diseases

We report a case of pseudotumoral pelvic actinomycosis with lumbosacral spinal involvement in a 21 year-old woman. The radiological work-up showed a pseudotumoral left ovarian lesion extended to sacral spine, which involved the fifth lumbar vertebra. Diagnosis of actinomycosis was established in histopathological examination of the tubo-ovarian mass under laparotomy. After four months of treatment with ofloxacin and rifampicin evolution was marked by improvement of general health and infection, associated to a progressive recovery of motricity of the lower limbs. Early diagnosis of pelvic actinomycosis may prevent the occurrence of rare but severe neurological complications of this disease.

Topics: Actinomycosis; Adult; Female; Humans; Lumbar Vertebrae; Ofloxacin; Ovarian Diseases; Pelvic Infection; Rifampin; Sacrum

The case of a 25-y-old woman with brucellar ovarian abscess is reported. Cultures of blood, ascites and a pus specimen yielded Brucella melitensis. The possibility of ovarian abscess being caused by Brucella melitensis should be considered in countries where the infection is endemic.

Topics: Abscess; Adult; Anti-Bacterial Agents; Ascites; Brucella melitensis; Brucellosis; Doxycycline; Female; Humans; Laparoscopy; Ovarian Diseases; Rifampin

Topics: Adult; Antibiotics, Antitubercular; Antitubercular Agents; Diagnosis, Differential; Female; Humans; Isoniazid; Ovarian Diseases; Pelvis; Rifampin; Tuberculosis, Female Genital; Tuberculosis, Miliary; Uterine Neoplasms

A study has been made of 710 patients with proved gynaecological tuberculosis investigated between January 1, 1951 and March 31, 1985. The main presenting symptoms in order of frequency were infertility, pelvic pain, excessive menstrual loss and amenorrhoea. The average age was 31 years at first attendance, only 16% of married women had been pregnant and palpable adnexal masses were found in 47%. Seven drug programmes have been used, the best results being obtained with the current regimen employing rifampicin, ethambutol and isoniazid. Where drug treatment failed, surgery under further drug cover was successfully employed. Toxic drug reactions occurred in 114 patients.

Topics: Adolescent; Adult; Aged; Drug Administration Schedule; Ethambutol; Fallopian Tube Diseases; Female; Humans; Isoniazid; Middle Aged; Ovarian Diseases; Rifampin; Tuberculosis, Female Genital; Uterine Diseases