rifampin and Gonorrhea

rifampin has been researched along with Gonorrhea* in 51 studies

Reviews

1 review(s) available for rifampin and Gonorrhea

ArticleYear
Rifampicin: a review.
    Drugs, 1971, Volume: 1, Issue:5

    Topics: Abnormalities, Drug-Induced; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Chemical and Drug Induced Liver Injury; Drug Interactions; Drug Resistance, Microbial; Endocarditis, Bacterial; Gonorrhea; Humans; Intestinal Absorption; Leprosy; Meningococcal Infections; Mycobacterium; Respiratory Tract Infections; Rifampin; Thrombocytosis; Tuberculosis; Tuberculosis, Pulmonary; Urologic Diseases; Viruses

1971

Trials

5 trial(s) available for rifampin and Gonorrhea

ArticleYear
Rifampicin-erythromycin combination for the treatment of gonococcal urethritis in men.
    The Southeast Asian journal of tropical medicine and public health, 1984, Volume: 15, Issue:3

    A total of 184 men with uncomplicated gonococcal urethritis were treated with a single oral dose of rifampicin 900 mg and erythromycin stearate 1 gm. The cure rate on day 3 was 95.1%, 175 were cured and 9 failed (4.9%). Of all the Neisseria gonorrhoeae isolated, 86 were PPNG (46.7%). There was no difference in failure rate among patients with PPNG or with non-PPNG. With the exception of self-limited gastrointestinal disturbance, side effects were minimal. The value of this combination for the treatment of uncomplicated gonococcal urethritis in men is promising and deserves further study.

    Topics: Adolescent; Adult; Aged; Ampicillin; Clinical Trials as Topic; Costs and Cost Analysis; Drug Therapy, Combination; Erythromycin; Gonorrhea; Humans; Male; Middle Aged; Neisseria gonorrhoeae; Penicillin Resistance; Probenecid; Rifampin; Thailand; Urethritis

1984
[Therapeutic effectiveness of benemycin in treating acute gonorrhea of the lower portion of the urogenital system in women].
    Vestnik dermatologii i venerologii, 1978, Issue:4

    Topics: Acute Disease; Adult; Clinical Trials as Topic; Drug Evaluation; Female; Genital Diseases, Female; Gonorrhea; Humans; Rifampin; Time Factors; Trichomonas Vaginitis; Urinary Tract Infections

1978
Single-dose rifampicin treatment of gonorrhoea.
    East African medical journal, 1976, Volume: 53, Issue:1

    Topics: Administration, Oral; Clinical Trials as Topic; Drug Evaluation; Female; Gonorrhea; Humans; Male; Rifampin

1976
Rifadin (rifampicin) in the treatment of gonorrhoea in Uganda. A controlled trial.
    The British journal of venereal diseases, 1971, Volume: 47, Issue:3

    Topics: Clinical Trials as Topic; Gonorrhea; Humans; Male; Penicillin G Procaine; Penicillin Resistance; Rifampin; Syphilis; Tuberculosis; Uganda; Urethritis

1971
Rifampicin compared with penicllin in the treatment of gonorrhea.
    Chemotherapy, 1971, Volume: 16, Issue:5

    Topics: Adult; Clinical Trials as Topic; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillin G; Penicillin G Procaine; Penicillin Resistance; Penicillins; Rifampin

1971

Other Studies

45 other study(ies) available for rifampin and Gonorrhea

ArticleYear
Rifampicin Resistance Associated with
    Microbiology spectrum, 2022, 06-29, Volume: 10, Issue:3

    Due to increasing rates of antimicrobial resistance (AMR) in Neisseria gonorrhoeae, alternative treatments should be considered. To assess rifampicin's potential as a gonorrhea treatment, we used

    Topics: Anti-Bacterial Agents; Austria; Bacterial Proteins; DNA-Directed RNA Polymerases; Drug Resistance, Bacterial; Gonorrhea; Humans; Microbial Sensitivity Tests; Mutation; Neisseria gonorrhoeae; Rifampin

2022
Characterisation of a tet(M)-carrying plasmid from Neisseria meningitidis.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 34, Issue:6

    Topics: Base Sequence; Conjugation, Genetic; Drug Resistance, Microbial; Genes, Bacterial; Gonorrhea; Homosexuality; Humans; Molecular Sequence Data; Neisseria meningitidis; Pharynx; Plasmids; Restriction Mapping; Rifampin; Sequence Homology, Nucleic Acid; Tetracycline Resistance

1994
Meningococcal prophylaxis.
    The Pediatric infectious disease journal, 1993, Volume: 12, Issue:9

    Topics: Adult; Ceftriaxone; Child; Gonorrhea; Humans; Meningitis, Meningococcal; Rifampin; Spectinomycin

1993
[In vitro sensitivity of Neisseria gonorrhoeae to 10 antibiotics and response of gonococcal urethritis to rifampicin].
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 1988, Volume: 123, Issue:10

    Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Rifampin; Urethritis

1988
[Comparative results in treating gonorrhea with vibramycin, benemycin and sodium fucidin].
    Vestnik dermatologii i venerologii, 1988, Issue:10

    Topics: Adolescent; Adult; Chronic Disease; Doxycycline; Drug Evaluation; Drug Therapy, Combination; Female; Fusidic Acid; Gonorrhea; Humans; Male; Middle Aged; Recurrence; Rifampin; Staphylococcal Toxoid

1988
The combination of rifampicin-erythromycin in the treatment of gonococcal urethritis in men.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1985, Volume: 68, Issue:11

    Topics: Cefotaxime; Drug Therapy, Combination; Erythromycin; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillinase; Rifampin; Urethritis

1985
Treatment of uncomplicated gonorrhoea in women with a combination of rifampicin and erythromycin.
    The British journal of venereal diseases, 1984, Volume: 60, Issue:5

    One hundred women with uncomplicated gonorrhoea (in five cases due to penicillinase producing strains of Neisseria gonorrhoeae (PPNG)) were treated with a single oral dose of rifampicin 900 mg and erythromycin stearate 1 g. N gonorrhoeae was reisolated from the oropharynx of one patient, who was infected with a PPNG strain, but was eradicated from the genital tract in 100% of cases. The combination eradicated Chlamydia trachomatis from only 10 (28%) of the 36 patients infected. Side effects were predominantly mild and consisted of transient nausea. The treatment merits evaluation in areas with a high incidence of PPNG strains.

    Topics: Adolescent; Adult; Chlamydia Infections; Chlamydia trachomatis; Drug Therapy, Combination; Erythromycin; Female; Gonorrhea; Humans; Middle Aged; Rifampin

1984
[1,200 mg rifampicin(Rimactan) as an oral one-dose treatment of uncomplicated gonorrhea in women].
    Dermatologica, 1983, Volume: 167, Issue:5

    40 women were treated for uncomplicated genital gonorrhoea, verified by culture, with a single oral dose of 1,200 mg rifampicin (Rimactan). The ages ranged between 15 and 51 years. In 33 patients that could be evaluated, the gonorrhoea was cured. In 8 of 18 patients the preexistent vaginal discharge improved. 4 women experienced six different side effects which were probably related to rifampicin. The 1,200-mg rifampicin oral one-dose treatment is a reliable, efficient, and well-tolerated therapy of uncomplicated gonorrhoea in women.

    Topics: Administration, Oral; Adolescent; Adult; Female; Gonorrhea; Humans; Middle Aged; Rifampin

1983
Acute gonococcal urethritis: treatment with a single dose of rifampicin.
    The Journal of international medical research, 1983, Volume: 11, Issue:1

    A total of 103 patients with acute gonococcal urethritis were treated with a single 1,200 mg dose of rifampicin. A 91 . 3% cure rate was obtained, as proved by the negative bacteriological controls effected on the 7th and 14th days after the initiation of therapy. Three pharyngeal infections and one ano-rectal infection responded successfully to the treatment. No signs of drug intolerance were detected with the stated dose. Reactivity to the VDRL test was not impaired during the duration of the study and three reactive cases were discovered. In previous studies of gonorrhoea we had observed a significant discrepancy between urine cultures and the urethral smears and, in view of this, it was decided to adopt the latter alone as a routine procedure. The proposed dose does not originate resistance to rifampicin in either the Hansen or Koch bacilli.

    Topics: Drug Evaluation; Drug Tolerance; Gonorrhea; Humans; Male; Rifampin; Syphilis Serodiagnosis; Urethritis

1983
[Comparison of amoxycillin, rifampicin and erythromycin in the single-dose peroral treatment of gonorrhea].
    Ceskoslovenska dermatologie, 1982, Volume: 57, Issue:4

    Topics: Administration, Oral; Amoxicillin; Erythromycin; Gonorrhea; Humans; Male; Rifampin

1982
[Clinical laboratory evaluation of the rifampicin's therapeutic effectiveness in treating fresh gonorrhea in men].
    Vestnik dermatologii i venerologii, 1981, Issue:11

    Topics: Adolescent; Adult; Drug Evaluation; Gonorrhea; Humans; Male; Middle Aged; Rifampin; Time Factors; Urethra; Urethritis

1981
[One-dose peroral treatment of acute male gonorrhoea by rifampicin (author's transl)].
    Ceskoslovenska dermatologie, 1979, Volume: 54, Issue:6

    Topics: Administration, Oral; Drug Administration Schedule; Gonorrhea; Humans; Male; Rifampin

1979
[Effectiveness of Rifampicin (Rimactan) in the treatment of gonorrhea].
    Przeglad dermatologiczny, 1976, Issue:6 Suppl

    Topics: Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Rifampin; Treponema pallidum

1976
Rifampicin in the treatment of gonorrhoea in males.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1976, Volume: 59, Issue:11

    Topics: Adolescent; Adult; Gonorrhea; Humans; Male; Rifampin; Thailand

1976
[Rifampicin therapy of gonococcal urethritis in men].
    Vestnik dermatologii i venerologii, 1976, Issue:10

    Topics: Adolescent; Adult; Gonorrhea; Humans; Male; Middle Aged; Rifampin; Urethritis

1976
[Treatment of gonorrhea with Rimactan Ciba].
    Przeglad dermatologiczny, 1976, Issue:6 Suppl

    Topics: Acute Disease; Adult; Chronic Disease; Gonorrhea; Humans; Male; Middle Aged; Rifampin

1976
[Rifampicin in the therapy of gonorrheal urethritis in men].
    Antibiotiki, 1976, Volume: 21, Issue:3

    The therapeutic efficiency of benemycin (rifampicin of Polish production), a semisynthetic antibiotic was studied in 96 male cases with gonorrhea urethritis. The antibiotic was used in a dose of 300 mg every 6 hours (2.1--3gm for the treatment course depending on the desease severity). Observation of the patients for 1--2 months showed etiological recovery in 91 (94.8 per cent) out of 96 patients. Postgonorrhea inflammatory processes were observed in 8.7 per cent of the cases. For studying late results of the treatmant 62 patients were observed for 3 to 12 months. Gonococci were isolated from none of the patients. No side reactions were found in the patients treated with rifampicin.

    Topics: Acute Disease; Adult; Drug Evaluation; Follow-Up Studies; Gonorrhea; Humans; Male; Rifampin; Time Factors; Urethritis

1976
Gonogrow, an improved, selective medium for the isolation of Neisseria gonorrhoeae.
    Health laboratory science, 1974, Volume: 11, Issue:3

    Topics: Bacteria; Candida albicans; Clindamycin; Colistin; Culture Media; Drug Storage; Gonorrhea; Humans; Neisseria gonorrhoeae; New York; Nystatin; Rifampin; Vancomycin

1974
Susceptibility of N. gonorrhoeae in vitro to antibiotics (penicillin, oxytetracycline, chloramphenicol and rifampicin).
    The Indian journal of medical research, 1973, Volume: 61, Issue:10

    Topics: Chloramphenicol; Gonorrhea; Humans; India; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Oxytetracycline; Penicillins; Rifampin

1973
[Rifampicin in the management of gonorrheal and bacterial urethritides].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1973, Nov-13, Volume: 62, Issue:46

    Topics: Bacterial Infections; Gonorrhea; Humans; Rifampin; Urethritis

1973
Treatment of venereal diseases.
    Tropical doctor, 1973, Volume: 3, Issue:4

    Topics: Chancroid; Drug Combinations; Erythromycin; Female; Gonorrhea; Granuloma Inguinale; Humans; Injections, Intramuscular; Kanamycin; Lymphogranuloma Venereum; Male; Metronidazole; Penicillin Resistance; Penicillins; Rifampin; Sexually Transmitted Diseases; Streptomycin; Sulfamethoxazole; Sulfonamides; Syphilis; Tetracycline; Trimethoprim; Urethritis

1973
Rifampicin in the treatment of acute gonorrhoea.
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1972, May-01, Volume: 47, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Female; Gonorrhea; Humans; Male; Middle Aged; Neisseria gonorrhoeae; Penicillin Resistance; Penicillins; Rifampin

1972
[Treatment of acute male gonococcal urethritis with a single dose of rifampicin].
    Revista medica de Chile, 1972, Volume: 100, Issue:9

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Child; Evaluation Studies as Topic; Gonorrhea; Humans; Male; Middle Aged; Rifampin

1972
[Rimactan in the therapy of gonorrhea].
    Lijecnicki vjesnik, 1972, Volume: 94, Issue:6

    Topics: Gonorrhea; Humans; Rifampin

1972
Treatment of gonorrhoea with a single oral dose of rifampicin.
    The Indian journal of medical research, 1972, Volume: 60, Issue:10

    Topics: Adolescent; Adult; Gonorrhea; Humans; Male; Middle Aged; Recurrence; Rifampin

1972
Treatment of gonorrhoea with trimethoprim-sulphamethoxazole and with rifampicin.
    The Medical journal of Australia, 1972, Jun-03, Volume: 1, Issue:23

    Topics: Adolescent; Adult; Anti-Infective Agents; Drug Combinations; Folic Acid Antagonists; Follow-Up Studies; Gonorrhea; Humans; Male; Middle Aged; Pyrimidines; Rifampin; Sulfamethoxazole; Trimethoprim

1972
Chemotherapy of gonorrhea: a review of current status.
    Canadian Medical Association journal, 1972, Nov-18, Volume: 107, Issue:10

    Topics: Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Erythromycin; Gonorrhea; Humans; Kanamycin; Penicillins; Probenecid; Rifampin; Sulfonamides; Trimethoprim

1972
Instant treatment of gonorrhoea in Singapore.
    Singapore medical journal, 1972, Volume: 13, Issue:4

    Topics: Ampicillin; Anti-Bacterial Agents; Gonorrhea; Humans; Male; Penicillins; Rifampin; Tetracycline; Time Factors

1972
Treatment of gonorrhoea with single oral doses. Results obtained with doxycycline or rifampicin compared with intramuscular penicillin.
    The British journal of venereal diseases, 1971, Volume: 47, Issue:2

    Topics: Anti-Bacterial Agents; Capsules; Gonorrhea; Humans; Injections, Intramuscular; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillin G; Rifampin; Staphylococcus

1971
Antibiotic resistant gonococci.
    British medical journal, 1971, Dec-18, Volume: 4, Issue:5789

    Topics: Ampicillin; Anti-Bacterial Agents; Doxycycline; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin Resistance; Penicillins; Rifampin

1971
[Therapy and therapy-control in uncomplicated gonorrhea].
    Lakartidningen, 1971, Sep-15, Volume: 68, Issue:38

    Topics: Doxycycline; Erythromycin; Female; Gonorrhea; Humans; Leucomycins; Lincomycin; Male; Neisseria gonorrhoeae; Penicillin G; Penicillin Resistance; Penicillins; Probenecid; Rifampin; Tetracycline

1971
[The sensitivity of gonococci to different antibiotics].
    Lakartidningen, 1971, Sep-15, Volume: 68, Issue:38

    Topics: Anti-Bacterial Agents; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin G; Penicillin Resistance; Procaine; Rifampin; Streptomycin; Syphilis; Tetracycline

1971
A 'single dose' treatment of gonococcal urethritis with rifampicin.
    The British journal of venereal diseases, 1971, Volume: 47, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Gonorrhea; Hospitalization; Humans; Injections, Intramuscular; Male; Outpatient Clinics, Hospital; Penicillin G; Penicillin G Benzathine; Penicillin G Procaine; Rifampin; Urethritis

1971
[Gonorrhea: its treatment with a single dose of rifampicin].
    Prensa medica argentina, 1971, Jun-25, Volume: 58, Issue:17

    Topics: Gonorrhea; Humans; Male; Rifampin

1971
Treatment of acute gonorrhoea with a single oral dose of rifampicin.
    The British journal of venereal diseases, 1971, Volume: 47, Issue:6

    Topics: Acute Disease; Administration, Oral; Female; Gonorrhea; Humans; Male; Penicillins; Probenecid; Rifampin

1971
Rifampicin (Rimactane) in the treatment of gonorrhoea.
    The British journal of venereal diseases, 1970, Volume: 46, Issue:2

    Topics: Adult; Gonorrhea; Humans; Male; Penicillin G Procaine; Rifampin; Spectinomycin; Streptomycin

1970
The treatment of gonorrhea with spectinomycin and rifampicin.
    Delaware medical journal, 1970, Volume: 42, Issue:11

    Topics: Antibiotics, Antineoplastic; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin Resistance; Rifampin; Spectinomycin

1970
Recent developments in the treatment of gonorrhoea.
    The British journal of venereal diseases, 1970, Volume: 46, Issue:2

    Rising failure rates with single injections of penicillin in gonorrhea are causing alarm. In the Far East, the failure rate is about 30% after single injections of 2.4 mega units of aqueous procaine penicillin. In London, although there is rising gonoccoccus resistance to penicillin, single injections of 1.2 mega units of aqueous procaine penicillin nets a cure rate of 85.8% to 91.5% in male patients. Other recent experiences in the treatment of gonorrhea in London men are outlined in this article. The failure rate was reduced to 5.8% when a single injection of 2.4 mega units of procaine penicillin was given. When 1 gm probenecid was given orally along with 1.2 mega units of procaine penicillin, the failure rate was 6.6%. Streptomycin is so ineffective now against gonorrhea that it is no longer acceptable even as a first treatment in patients who are allergic to penicillin. In London, the failure rate with streptomycin is 31.7%. Experts think the rate will jump to 85.8% in the next year. Many other antibiotics can be used against gonorrhea, but, as in the case of streptomycin, they may lose their effectiveness. Some recent experiences show that a combination of rolitetracycline by injection and tetracycline by mouth does not give as good results as a single injection of aqueous procaine penicillin but that comparable results can be obtained with single oral doses of rifampicin and superior results (95.7% success) were obtained with 2 oral doses of dementhylchlortetracycline.

    Topics: Demeclocycline; Drug Synergism; Gonorrhea; Humans; Male; Penicillin G Procaine; Penicillin Resistance; Probenecid; Rifampin; Rolitetracycline

1970
[Therapeutic effect of rifampicin on gonococcal urethritis].
    The Japanese journal of antibiotics, 1970, Volume: 23, Issue:5

    Topics: Administration, Oral; Adult; Gonorrhea; Humans; Male; Rifampin; Urethritis

1970
[Experiences with rimactan therapy of male gonorrhoeic urethritis].
    Dermatologica, 1970, Volume: 141, Issue:2

    Topics: Administration, Oral; Drug Hypersensitivity; Gonorrhea; Humans; Male; Penicillin Resistance; Rifampin; Urethritis

1970
In vitro susceptibility of Neisseria gonorrhoeae to nine antimicrobial agents.
    Applied microbiology, 1969, Volume: 18, Issue:1

    The in vitro action of nine antibiotics was tested by the agar streak method against 45 gonococcal strains isolated from penicillin-therapy failures. The penicillin susceptibility range of these strains was 0.003 to 1.32 mug/ml, and the tetracycline susceptibility range was 0.125 to 2.0 mug/ml. Minimal inhibitory concentrations of minocycline and doxycycline paralleled the activity of tetracycline and ranged from 0.125 to 1.0 mug/ml and 0.125 to 2.0 mug/ml, respectively. Rifampicin, with a narrow range of 0.5 to 1.0 mug/ml, inhibited 75% of the strains at 0.5 mug/ml. The range for cephaloridine and cephaloglycine was 0.5 to 20.0 mug/ml, but another cephalosporium derivative, cephalexin, exhibited greater activity in its range of 0.25 to 20.0 mug/ml. A semisynthetic penicillin, carbenicillin, with a range of 0.025 to 0.75 mug/ml, displayed more activity against the lower susceptible penicillin G gonococcal strains.

    Topics: Anti-Bacterial Agents; Cephaloridine; Cephalosporins; Gonorrhea; Humans; Neisseria gonorrhoeae; Penicillin G; Penicillin Resistance; Penicillins; Rifampin; Tetracycline

1969
[Management of blennorrhagia using a dose of Rimactan].
    Hospital (Rio de Janeiro, Brazil), 1969, Volume: 75, Issue:1

    Topics: Adolescent; Adult; Gonorrhea; Humans; Male; Middle Aged; Rifampin

1969
[Clinical experimentation with rifomycin in dermatologic and venereal diseases].
    Giornale di clinica medica, 1969, Volume: 50, Issue:10

    Topics: Adolescent; Adult; Aged; Child; Female; Gonorrhea; Humans; Male; Middle Aged; Rifampin; Skin Diseases

1969
[Therapy of gonococcal infection with rifamycin in a "single dose"].
    Minerva dermatologica, 1968, Volume: 43, Issue:10

    Topics: Adolescent; Adult; Female; Gonorrhea; Humans; Male; Middle Aged; Rifampin; Urethritis; Vaginitis

1968
Treatment of gonorrhoea with single oral doses of rifampicin.
    British medical journal, 1968, Dec-14, Volume: 4, Issue:5632

    Of 103 cases of acute uncomplicated gonorrhoea treated with single oral doses of 900 mg. of a new antibiotic rifampicin 89 were followed, and 10 (11.2%) apparent failures were found.Rifampicin gives results which compare favourably with those obtained under like conditions with similar doses of other orally administered antibiotics. It provides an alternative means of single-session therapy for patients in whom penicillin is contraindicated.

    Topics: Adult; Follow-Up Studies; Gonorrhea; Humans; Rifampin

1968