rifampin and Eyelid-Diseases

Topics: Anti-Bacterial Agents; Drug Therapy, Combination; Eyelid Diseases; Gram-Positive Bacterial Infections; Humans; Immunocompetence; Male; Middle Aged; Rifampin; Skin Diseases, Bacterial; Trimethoprim, Sulfamethoxazole Drug Combination

To report a case of bacillary angiomatosis of the lower eyelid, conjunctiva, and anterior orbit.. Interventional case report.. A 76-year-old immunocompromised male patient developed a firm vascularized nodule in his left lower eyelid and anterior orbit.. An excisional biopsy was performed. Histopathologic examination revealed an abnormal vascular proliferation and a mixed inflammatory infiltrate. A Warthin-Starry stain showed numerous bacilli. These findings are characteristic of bacillary angiomatosis. A serologic specimen was positive for antibodies to Bartonella Quintana.. The lower lid and anterior orbit are rare locations for bacillary angiomatosis. Our case brings to attention the increasing importance of Bartonella infection as a causative agent of ophthalmic diseases.

Topics: Aged; Angiomatosis, Bacillary; Anti-Bacterial Agents; Bartonella quintana; Conjunctival Diseases; Doxycycline; Drug Therapy, Combination; Eye Infections, Bacterial; Eyelid Diseases; Humans; Immunocompromised Host; Male; Orbital Diseases; Rifampin