rifampin and Appendicitis

We report a 52-year-old male presenting with a graft-appendiceal fistula four years after placement of an aorto-bifemoral Dacron prosthesis.. After appendectomy and total graft removal, the patient was treated with an in-situ repair using a rifampicin-silver graft. This kind of repair has only been reported in an animal study.. This infected aortic graft was treated successfully with a rifampicin-silver graft with a follow-up of 15 months without complications.. In-situ repair of a graft-appendiceal fistula with a rifampicin-silver graft seems a promising strategy. The long-term outcome needs to be studied.

Topics: Administration, Topical; Animals; Anti-Infective Agents; Appendicitis; Blood Vessel Prosthesis; Fistula; Humans; Male; Middle Aged; Prosthesis-Related Infections; Rifampin; Silver; Treatment Outcome

Appendicitis is a common cause of acute abdominal pain in children and is treated by an open or laparoscopic appendicectomy. Well documented post-operative complications include wound infection, intra-abdominal collection, and adhesional bowel obstruction. We present the rare case of right sacro-iliitis and iliac bone osteomyelitis in a 13 year old boy following an open appendicectomy for a perforated appendicitis.

Topics: Adolescent; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Appendectomy; Appendicitis; Ascitic Fluid; Ciprofloxacin; Clindamycin; Gram-Negative Bacteria; Humans; Laparotomy; Magnetic Resonance Imaging; Male; Metronidazole; Osteomyelitis; Rifampin; Rupture, Spontaneous; Sacroiliitis

Topics: Adolescent; Antitubercular Agents; Appendectomy; Appendicitis; Combined Modality Therapy; Drug Therapy, Combination; Humans; Isoniazid; Male; Pyrazinamide; Rifampin; Streptomycin; Tuberculosis, Gastrointestinal

Topics: Adult; Anti-Bacterial Agents; Appendicitis; Drug Therapy, Combination; Enterocolitis; Humans; Male; Nafcillin; Neutropenia; Osteomyelitis; Prosthesis-Related Infections; Rifampin; Staphylococcal Infections; Tibial Fractures