ribavirin has been researched along with Neoplasms in 56 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (16.07) | 18.7374 |
| 1990's | 11 (19.64) | 18.2507 |
| 2000's | 13 (23.21) | 29.6817 |
| 2010's | 21 (37.50) | 24.3611 |
| 2020's | 2 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Raju, N; Robins, RK; Smee, DF; Vaghefi, MM | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L | 1 |
| Chiu, CY; Hosing, C; Torres, HA; Westin, J; Zhang, HC | 1 |
| Daryani, N; Imam, U; Mumtaz, F; Parkash, A | 1 |
| Angelidakis, G; Blechacz, B; Economides, MP; Granwehr, BP; Hosry, J; Jiang, Y; Kaseb, A; Kyvernitakis, A; Mahale, P; Miller, E; Naing, A; Raad, II; Samaniego, F; Torres, HA | 1 |
| Brem, H; Casaos, J; Choi, J; Felder, R; Gorelick, NL; Huq, S; Kast, RE; Lott, T; Serra, R; Skuli, N; Suk, I; Tyler, B; Xia, Y | 1 |
| Fätkenheuer, G; Gillor, D; Kochanek, M; Platten, M; Salzberger, B | 1 |
| Chemaly, RF; Munsell, MF; Shah, DP | 2 |
| Robinson, JL | 1 |
| Borden, KL | 2 |
| Chavez-Blanco, A; De la Cruz-Hernandez, E; Dominguez-Gomez, G; Dueñas-Gonzalez, A; Gonzalez-Fierro, A; Medina-Franco, JL; Perez-Cardenas, E; Taja-Chayeb, L; Trujillo, J | 1 |
| Cai, Y; Lu, C; Makala, L; Wu, D | 1 |
| Berden, FA; Blokzijl, H; de Knegt, RJ; den Hollander, J; Drenth, JP; Friederich, P; Kievit, W; Kuiken, SD; van Erpecum, KJ; van Hoek, B; van Nieuwkerk, CM; van Vonderen, MG; Willemse, SB | 1 |
| Berger, A; Christopeit, M; Hauf, E; Hentrich, M; Heussel, CP; Kalkreuth, J; Klein, M; Kochanek, M; Lehners, N; Mayer, K; Penack, O; Rieger, C; Schalk, E; Silling, G; Vehreschild, M; von Lilienfeld-Toal, M; Weber, T; Wolf, HH | 1 |
| Economides, MP; Shigle, TL; Torres, HA | 1 |
| Jiang, JF; Liu, X; Shi, J; Sun, J | 1 |
| Camacho, F; Cooper, CL; Costiniuk, CT | 1 |
| Bode, U; Eis-Huebinger, AM; Panning, M; Schildgen, O; Simon, A | 1 |
| Bortolotti, F; Brugiolo, A; Carli, M; Cesaro, S; Guido, M; Petris, MG | 1 |
| Agaoglu, L; Anak, S; Atay, D; Devecioglu, O; Garipardic, M; Karakas, Z; Ozturk, G; Unuvar, A | 1 |
| Schwarz, KB | 1 |
| Sherman, KE | 1 |
| Borden, KL; Culjkovic-Kraljacic, B | 1 |
| Bodey, GP; Champlin, RE; Chemaly, RF; Hosing, C; Munsell, MF; Raad, II; Rathod, DB; Saifan, C; Shah, DP; Torres, HA | 1 |
| Kökeny, S; Olah, E; Orbán, TI; Shen, F; Weber, G | 1 |
| Anaissie, EJ; Aslan, T; Barlogie, B; Desikan, R; Fassas, A; Mahfouz, TH; Pouli, A | 1 |
| Weber, G | 3 |
| Bozsik, A; Keszei, M; Kökény, S; Oláh, E; Papp, J | 1 |
| Ansari, S; Bateni, F; Vossogh, P | 1 |
| White, DO | 1 |
| Barzi, A; Cappellacci, L; Carrell, C; Franchetti, P; Goldstein, BM; Grifantini, M; Jayaram, HN; Nocentini, G; O'Connor, A; Yang, H | 1 |
| Look, KY; Prajda, N; Singhal, RL; Sledge, GW; Weber, G; Yeh, YA | 1 |
| Bocsi, J; Jeney, A; Ladányi, A; Lapis, K; Paku, S; Pogány, G; Rśó, E; Tímár, J; Tóvári, J | 1 |
| Cappellacci, L; De Montis, A; Franchetti, P; Goldstein, BM; Grifantini, M; Gurudutt, VV; Jayaram, HN; Jones, WD; La Colla, P; Loi, AG; Perra, G; Schneider, BP; Sheikha, GA; Sint, T | 1 |
| Csokay, B; Li, W; Look, KY; Olah, E; Prajda, N; Shen, F; Weber, G; Yang, H; Yeh, A | 1 |
| Li, W; Shen, F; Weber, G | 1 |
| Cooney, DA; Grusch, M; Jayaram, HN; Krupitza, G | 1 |
| Li, W; Prajda, N; Shen, F; Weber, G; Yang, H | 1 |
| Akesson, A; Christensson, B; Widell, A; Wiebe, T | 1 |
| Grifantini, M | 1 |
| Raicevic, N; Samardzic, T; Stosic-Grujicic, S; Trajkovic, V | 1 |
| Brown, TD; Burris, HA; Havlin, KA; O'Rourke, TJ; Rodriguez, GI; Wall, JG; Weiss, GR | 1 |
| Cheson, BD; Grem, JL; Hawkins, MJ; King, SA; Rubinstein, L; Shoemaker, DD | 1 |
| Maroun, JA; Stewart, DJ | 1 |
| Diala, ES; Jacobsen, SJ; Mangum, JH; Nyhan, WL; Page, T; Robins, RK | 1 |
| Ogawa, M | 1 |
| Bishop, J; Coates, A; Fox, R; Grygiel, J; Raghavan, D; Sampson, D; Woods, R | 1 |
| Berry, DA; Besserer, JA; Boritzki, TJ; Cook, PD; Fry, DW; Jackson, RC; Leopold, WR | 1 |
| Koeller, JM; Tormey, DC; Trump, DL; Tutsch, KD | 1 |
| Boldt, DH; Clark, GM; Hersh, MR; Kuhn, JG; Melink, TJ; Patton, TF; Siegler, R; Sternson, LA; Von Hoff, DD | 1 |
| Balis, FM; Cogliano-Shutta, NA; Ettinger, LJ; Heideman, RL; Holcenberg, JS; Lange, BJ; Packer, RJ; Sallan, SE; Smithson, WA; Zimm, S | 1 |
17 review(s) available for ribavirin and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction | 2015 |
The Use of Ribavirin as an Anticancer Therapeutic: Will It Go Viral?
Topics: Antineoplastic Agents; Humans; Neoplasms; Ribavirin | 2019 |
When will resistance be futile?
Topics: Drug Resistance, Neoplasm; Eukaryotic Initiation Factor-4E; Glucuronic Acid; Glucuronosyltransferase; Humans; Neoplasms; Ribavirin; Transcription Factors; Zinc Finger Protein GLI1 | 2014 |
Targeting translation: eIF4E as an emerging anticancer drug target.
Topics: Animals; Antineoplastic Agents; Cyclin D1; Epoxy Compounds; Eukaryotic Initiation Factor-4E; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Macrolides; Neoplasms; Oligonucleotides, Antisense; Protein Biosynthesis; Ribavirin; RNA, Small Interfering; Signal Transduction; Sirolimus; Survivin; Thiazoles; Triterpenes; Vascular Endothelial Growth Factor A | 2016 |
Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology.
Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Community-Acquired Infections; Cytosine; Germany; Hand Hygiene; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Influenza, Human; Lung; Masks; Medical Oncology; Metapneumovirus; Neoplasms; Neuraminidase; Nucleic Acid Amplification Techniques; Organophosphonates; Oseltamivir; Paramyxoviridae Infections; Patient Isolation; Pneumonia, Viral; Respiratory Syncytial Virus Infections; Respiratory Tract Infections; Ribavirin; Tomography, X-Ray Computed; Virus Diseases | 2016 |
Thymosin alpha 1 for treatment of hepatitis C virus: promise and proof.
Topics: Carcinoma, Hepatocellular; Chronic Disease; Clinical Trials as Topic; Hepacivirus; Humans; Interferons; Liver Cirrhosis; Liver Neoplasms; Neoplasms; Randomized Controlled Trials as Topic; Ribavirin; Thymalfasin; Thymosin; Treatment Outcome | 2010 |
Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?
Topics: Acute Disease; Antiviral Agents; Eukaryotic Initiation Factor-4E; Humans; IMP Dehydrogenase; Leukemia, Myeloid; Neoplasms; Protein Binding; Ribavirin | 2010 |
Targeting signal transduction.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Cell Line, Tumor; Guanosine Triphosphate; Humans; Ligands; Neoplasms; Ribavirin; Signal Transduction | 2003 |
Down-regulation of increased signal transduction capacity in human cancer cells.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Cell Proliferation; Down-Regulation; Drug Synergism; Genistein; Half-Life; Humans; Inositol 1,4,5-Trisphosphate; Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Quercetin; Ribavirin; Signal Transduction; Tamoxifen; Tumor Cells, Cultured; Type C Phospholipases | 2005 |
Modulation of cancer pathways by inhibitors of guanylate metabolism.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Guanosine Monophosphate; Humans; IMP Dehydrogenase; Neoplasms; Ribavirin; Signal Transduction | 2006 |
Antiviral chemotherapy.
Topics: Acyclovir; Amantadine; Animals; Antiviral Agents; Bromodeoxyuridine; Female; Hepatitis B; Herpes Genitalis; Herpes Simplex; Herpes Zoster; Humans; Idoxuridine; In Vitro Techniques; Interferons; Male; Neoplasms; Papillomaviridae; Respiratory Tract Infections; Ribavirin; Rimantadine; Tumor Virus Infections; Vidarabine | 1984 |
Role of purine metabolism in regulation of signal transduction in human carcinoma cells.
Topics: Antimetabolites, Antineoplastic; Deoxyguanine Nucleotides; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Inosine Monophosphate; Leukemia; Neoplasms; Purines; Ribavirin; Signal Transduction | 1998 |
Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis.
Topics: Antineoplastic Agents; Apoptosis; cdc25 Phosphatases; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Guanosine Triphosphate; HL-60 Cells; Humans; IMP Dehydrogenase; Leukemia, Myeloid; Neoplasms; Nucleosides; Organoselenium Compounds; Ovarian Neoplasms; Protein Tyrosine Phosphatases; Ribavirin; Ribonucleosides; RNA, Messenger; Time Factors; Tumor Cells, Cultured | 1999 |
Tiazofurine ICN Pharmaceuticals.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Contraindications; Drugs, Investigational; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Neoplasms; Ribavirin; Structure-Activity Relationship | 2000 |
New anticancer agents.
Topics: Alkaloids; Animals; Antineoplastic Agents; Azacitidine; Biphenyl Compounds; Chrysenes; Deoxycytidine; Echinomycin; Epirubicin; Etanidazole; Flavonoids; Gemcitabine; Guanidines; Humans; Idarubicin; Menogaril; Mitoguazone; Neoplasms; Nitroimidazoles; Nogalamycin; Organoplatinum Compounds; Paclitaxel; Pentostatin; Polymers; Propylene Glycols; Ribavirin; Sulfonylurea Compounds; Trimetrexate; Vidarabine Phosphate | 1991 |
Clinical toxicity associated with tiazofurin.
Topics: Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Evaluation; Female; Heart Diseases; Humans; Infusions, Intravenous; Leukopenia; Male; Nausea; Neoplasms; Ribavirin; Ribonucleosides; Ulcer; Vomiting | 1990 |
[Current status of clinical results of new antitumor drugs].
Topics: Aminoacridines; Amsacrine; Anthracyclines; Anthraquinones; Antibiotics, Antineoplastic; Antineoplastic Agents; Aziridines; Benzoquinones; Carboplatin; Carubicin; Cisplatin; Daunorubicin; Doxorubicin; Eflornithine; Epirubicin; Humans; Idarubicin; Mitoxantrone; Naphthacenes; Neoplasms; Organoplatinum Compounds; Ornithine; Ribavirin | 1985 |
1 trial(s) available for ribavirin and Neoplasms
| Article | Year |
|---|---|
An adaptive randomized trial of an intermittent dosing schedule of aerosolized ribavirin in patients with cancer and respiratory syncytial virus infection.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosols; Aged; Antiviral Agents; Female; Humans; Male; Middle Aged; Neoplasms; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Respiratory Tract Infections; Ribavirin; Treatment Outcome; Young Adult | 2012 |
38 other study(ies) available for ribavirin and Neoplasms
| Article | Year |
|---|---|
Synthesis and biological properties of purine and pyrimidine 5'-deoxy-5'-(dihydroxyphosphinyl)-beta-D-ribofuranosyl analogues of AMP, GMP, IMP, and CMP.
Topics: Adenosine Monophosphate; Animals; Chemical Phenomena; Chemistry; Colonic Neoplasms; Cytidine Monophosphate; Cytosine Nucleotides; Guanine Nucleotides; Guanosine Monophosphate; Humans; Inosine Monophosphate; Inosine Nucleotides; Leukemia; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Neoplasms; Phosphorylation; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Tumor Cells, Cultured; Viruses | 1989 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Hepatitis E Virus Infection in Cancer Patients.
Topics: Adult; Female; Hematologic Neoplasms; Hepatitis E; Hepatitis E virus; Humans; Male; Neoplasms; Retrospective Studies; Ribavirin; RNA; United States; Viremia | 2022 |
Usefulness Of Sofosbuvir And Daclatasvir Combination In The Treatment Of HCV Infection In Childhood Cancer Patients: Experience From A Tertiary Care Hospital.
Topics: Adolescent; Antiviral Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Humans; Male; Neoplasms; Pyrrolidines; Retrospective Studies; Ribavirin; Sofosbuvir; Tertiary Care Centers; Treatment Outcome | 2023 |
Sofosbuvir-Based Therapy in Hepatitis C Virus-Infected Cancer Patients: A Prospective Observational Study.
Topics: Aged; Antiviral Agents; Benzimidazoles; Breast Neoplasms; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Fluorenes; Head and Neck Neoplasms; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Interferons; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Neoplasms; Polyethylene Glycols; Prospective Studies; Pyrrolidines; Ribavirin; Simeprevir; Sofosbuvir; Sustained Virologic Response; Valine | 2019 |
Aerosolized ribavirin for patients with cancer and respiratory syncytial virus infection.
Topics: Aerosols; Antiviral Agents; Female; Humans; Male; Neoplasms; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Respiratory Tract Infections; Ribavirin | 2013 |
Reply to Fätkenheuer et al.
Topics: Aerosols; Antiviral Agents; Female; Humans; Male; Neoplasms; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Respiratory Tract Infections; Ribavirin | 2013 |
Ribavirin for upper respiratory tract infections.
Topics: Aerosols; Antiviral Agents; Female; Humans; Male; Neoplasms; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Respiratory Tract Infections; Ribavirin | 2013 |
Reply to Robinson.
Topics: Aerosols; Antiviral Agents; Female; Humans; Male; Neoplasms; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Respiratory Tract Infections; Ribavirin | 2013 |
Ribavirin as a tri-targeted antitumor repositioned drug.
Topics: Antineoplastic Agents; Antiviral Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Drug Repositioning; Enhancer of Zeste Homolog 2 Protein; Eukaryotic Initiation Factor-4E; HeLa Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; IMP Dehydrogenase; MCF-7 Cells; Neoplasms; Polycomb Repressive Complex 2; Ribavirin; RNA, Small Interfering | 2015 |
Limited Generalizability of Registration Trials in Hepatitis C: A Nationwide Cohort Study.
Topics: Adult; Aged; Anemia; Antiviral Agents; Cardiovascular Diseases; Eligibility Determination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Neoplasms; Netherlands; Neutropenia; Patient Selection; Polyethylene Glycols; Recombinant Proteins; Regression Analysis; Retrospective Studies; Ribavirin; Risk Factors | 2016 |
Letter: should direct-acting antiviral drugs be used concomitantly with chemotherapeutic drugs in hepatitis C virus-infected patients with cancer? Authors' reply.
Topics: Antiviral Agents; Hepacivirus; Hepatitis C, Chronic; Humans; Neoplasms; Ribavirin | 2017 |
Letter: should direct-acting antiviral drugs be used concomitantly with chemotherapeutic drugs in hepatitis C virus-infected patients with cancer?
Topics: Antiviral Agents; Hepacivirus; Hepatitis C, Chronic; Humans; Neoplasms; Ribavirin | 2017 |
Erythropoiesis-stimulating agent use for anemia induced by interferon-ribavirin treatment in patients with hepatitis C virus infection is not associated with increased rates of cardiovascular disease, thrombosis, malignancy, or death.
Topics: Adult; Anemia; Antiviral Agents; Cardiovascular Diseases; Female; Hematinics; Hemoglobins; Hepatitis C; Humans; Interferons; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasms; Retrospective Studies; Ribavirin; Treatment Outcome | 2008 |
Respiratory syncytial virus infection in patients with cancer: still more questions than answers.
Topics: Adolescent; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antiviral Agents; Child; Child, Preschool; Female; Hematologic Neoplasms; Humans; Infant; Male; Neoplasms; Palivizumab; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Ribavirin | 2008 |
An updated follow-up of chronic hepatitis C after three decades of observation in pediatric patients cured of malignancy.
Topics: Adolescent; Adult; Alanine Transaminase; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Cohort Studies; Drug Therapy, Combination; Female; Fibrosis; Follow-Up Studies; Genotype; Hepatitis C, Chronic; Humans; Interferons; Male; Neoplasms; Ribavirin; RNA, Messenger; Survival Rate; Treatment Outcome; Young Adult | 2010 |
Respiratory syncytial virus infection outbreak among pediatric patients with oncologic diseases and/or BMT.
Topics: Antiviral Agents; Bone Marrow Transplantation; Child, Preschool; Cross Infection; Disease Outbreaks; Female; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Immunologic Factors; Male; Neoplasms; Respiratory Syncytial Virus Infections; Ribavirin; Turkey | 2010 |
Hepatitis C: not so indolent in survivors of pediatric cancer?
Topics: Adolescent; Adult; Alanine Transaminase; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Interferons; Neoplasms; Ribavirin; RNA, Messenger; Young Adult | 2010 |
Targeting the oncogene eIF4E in cancer: From the bench to clinical trials.
Topics: Antiviral Agents; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Eukaryotic Initiation Factor-4E; Humans; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Neoplasms; Oncogenes; Ribavirin | 2011 |
The natural history of respiratory syncytial virus infection in cancer and transplant patients: implications for management.
Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Body Fluids; Female; Humans; Immunoglobulins, Intravenous; L-Lactate Dehydrogenase; Male; Middle Aged; Multiple Myeloma; Multivariate Analysis; Neoplasms; Peripheral Blood Stem Cell Transplantation; Renal Insufficiency; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Ribavirin; Time Factors | 2004 |
Metabolic regulation and chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Guanosine Monophosphate; Homeostasis; Humans; Neoplasms; Ribavirin | 2006 |
Treating children with chronic hepatitis C after malignancy in a single center.
Topics: Adolescent; Adult; Antiviral Agents; Blood Component Transfusion; Child; Female; Follow-Up Studies; Hepatitis C, Chronic; Humans; Infant; Interferons; Male; Neoplasms; Ribavirin | 2007 |
Furanfurin and thiophenfurin: two novel tiazofurin analogues. Synthesis, structure, antitumor activity, and interactions with inosine monophosphate dehydrogenase.
Topics: Animals; Antineoplastic Agents; Crystallography, X-Ray; Humans; IMP Dehydrogenase; Inosine Monophosphate; Magnetic Resonance Spectroscopy; Mice; NAD; Neoplasms; Ribavirin; Ribonucleosides; Ribonucleotides; Tumor Cells, Cultured | 1995 |
Regulation of signal transduction.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Cell Division; Diet; Fasting; Female; Humans; Inositol 1,4,5-Trisphosphate; Male; Neoplasms; Phosphatidylinositols; Phosphotransferases (Alcohol Group Acceptor); Quercetin; Rats; Rats, Wistar; Ribavirin; Signal Transduction; Tumor Cells, Cultured | 1995 |
The antimetabolite Tiazofurin (TR) inhibits glycoconjugate biosynthesis and invasiveness of tumour cells.
Topics: Amino Acid Sequence; Animals; Antimetabolites, Antineoplastic; Cell Adhesion; Cell Movement; Dose-Response Relationship, Drug; Flow Cytometry; Glycoconjugates; Humans; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Transplantation; Neoplasms; Ribavirin; Tumor Cells, Cultured | 1996 |
Synthesis, structure, and antiproliferative activity of selenophenfurin, an inosine 5'-monophosphate dehydrogenase inhibitor analogue of selenazofurin.
Topics: Animals; Antineoplastic Agents; Cell Division; Computer Simulation; Crystallography, X-Ray; Enzyme Inhibitors; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Inosine Monophosphate; Leukemia; Lymphoma; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Structure; Neoplasms; Organoselenium Compounds; Ribavirin; Ribonucleosides; Tumor Cells, Cultured | 1997 |
Regulation of the signal transduction program by drugs.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Genistein; Humans; IMP Dehydrogenase; Inositol 1,4,5-Trisphosphate; Neoplasms; Phosphatidylinositols; Phosphotransferases (Alcohol Group Acceptor); Quercetin; Rats; Ribavirin; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases | 1997 |
Amplification of signal transduction capacity and down-regulation by drugs.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Differentiation; Cell Division; Colonic Neoplasms; Down-Regulation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Genistein; Humans; Inositol Phosphates; Liver Neoplasms, Experimental; Neoplasms; Ovarian Neoplasms; Phosphoric Monoester Hydrolases; Rats; Ribavirin; Signal Transduction; Tamoxifen; Tumor Cells, Cultured | 1999 |
Interferon-alpha and ribavirin treatment of hepatitis C in children with malignancy in remission.
Topics: Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cross Infection; Disease Outbreaks; Drug Therapy, Combination; Hepatitis C; Humans; Interferon-alpha; Neoplasms; Remission Induction; Ribavirin | 2000 |
Tumor cell-specific inhibition of inducible nitric oxide synthase activation by tiazofurin.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; DNA-Binding Proteins; Enzyme Inhibitors; Interferon Regulatory Factor-1; Interferon-gamma; Lipopolysaccharides; Mice; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphoproteins; Ribavirin; RNA, Messenger | 2001 |
Sir Hans A. Krebs Centenary Lecture: cancer and clinical targeting.
Topics: Animals; Antineoplastic Agents; Apoptosis; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Down-Regulation; Guanosine Triphosphate; History, 20th Century; Humans; Ischemia; Kidney Neoplasms; Leukemia; Models, Biological; Neoplasms; Ribavirin; Signal Transduction; Time Factors; Tumor Cells, Cultured | 2001 |
Phase I study of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193).
Topics: Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Ribavirin; Ribonucleosides | 1990 |
Synergistic activity of purine metabolism inhibitors in cultured human tumor cells.
Topics: 3-Deazauridine; Antimetabolites, Antineoplastic; Cell Division; Cells, Cultured; Drug Synergism; Humans; Inosine; Neoplasms; Ribavirin | 1987 |
Phase I and pharmacokinetic study of tiazofurin (NSC 286193) administered by 5-day continuous infusion.
Topics: Adult; Chromatography, High Pressure Liquid; Conjunctivitis; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Female; Humans; Kinetics; Male; Middle Aged; Neoplasms; Neutropenia; Ribavirin; Ribonucleosides | 1986 |
Biochemical and antitumor activity of tiazofurin and its selenium analog (2-beta-D-ribofuranosyl-4-selenazolecarboxamide).
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Humans; Mice; Neoplasms; Nucleic Acids; Organoselenium Compounds; Ribavirin; Ribonucleosides; Ribonucleotides; Selenium | 1985 |
Phase I clinical study with pharmacokinetic analysis of 2-beta-D-ribofuranosylthiazole-4-carboxamide (NSC 286193) administered as a five-day infusion.
Topics: Adult; Aged; Antineoplastic Agents; Bone Marrow; Creatine Kinase; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Parenteral; Kinetics; Male; Middle Aged; Neoplasms; Nervous System; Purines; Ribavirin; Ribonucleosides; Skin | 1985 |
Phase I evaluation and pharmacokinetics of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193).
Topics: Adult; Aged; Antineoplastic Agents; Aspartate Aminotransferases; Bone Marrow; Creatine Kinase; Drug Evaluation; Female; Humans; Kinetics; Lymphocytes; Male; Middle Aged; Neoplasms; Ribavirin; Ribonucleosides; Uric Acid | 1985 |
Pediatric phase I trial and pharmacokinetic study of tiazofurin (NSC 286193).
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Drug Evaluation; Humans; Kidney; Kinetics; Neoplasms; Ribavirin; Ribonucleosides | 1985 |