ribavirin has been researched along with Insulin Sensitivity in 92 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 33 (35.87) | 29.6817 |
2010's | 57 (61.96) | 24.3611 |
2020's | 2 (2.17) | 2.80 |
Authors | Studies |
---|---|
Altıntaş, E; Ateş, F; Özdoğan, O; Sezgin, O; Üçbilek, E; Yaraş, S | 1 |
Cázares-Cortazar, A; Chapararro-Sánchez, A; de la Luz Martínez-Rodríguez, M; Gaytán-Martínez, J; Mata-Marín, JA; Mauss, S; Ocaña-Mondragón, A; Uribe-Noguez, LA; Villavicencio-Ferrel, PE | 1 |
Abdel Alem, S; Abdellatif, Z; Adel, E; Elsharkawy, A; Esmat, G; Fouad, R; Hussein, MS; Musa, S; Nagy, A; Yosry, A | 1 |
Abdel-Razik, A; El-Wakeel, N; Eldars, W; Elgamal, A; Elkashef, W; Elzehery, R; Farag, R; Mousa, N; Shabana, W | 1 |
Crisan, D; Grigorescu, M; Grigorescu, MD; Radu, C; Suciu, A | 1 |
Cooper, CL; Crawley, A; Doyle, MA; Galanakis, C; Mulvihill, E | 1 |
Chi, X; Gao, X; Li, Y; Lv, J; Niu, J; Sun, H; Wang, X; Wu, R; Yu, G | 1 |
Ahmed, A; Doss, W; Saad, Y; Saleh, DA | 1 |
Chan, CH; Gilliver, RS; Hansen, RD; Jones, BE | 1 |
Arama, V; Popescu, C; Popescu, GA | 1 |
Furusyo, N; Hayashi, J; Hayashi, T; Ihara, T; Ikezaki, H; Kainuma, M; Kajiwara, E; Murata, M; Ogawa, E; Okada, K; Satoh, T; Takahashi, K; Toyoda, K | 1 |
Andreone, P; Coate, B; DeMasi, R; Diago, M; Focaccia, R; Foster, GR; Horban, A; Lawitz, EJ; Lonjon-Domanec, I; Negro, F; Picchio, G; Pol, S; Roberts, S; Serfaty, L; Witek, J; Younossi, Z; Zeuzem, S | 1 |
Alston-Smith, B; Andersen, J; Chung, RT; Glesby, MJ; Hadigan, C; Kitch, D; Luetkemeyer, A; Marks, KM; Tien, P | 1 |
Jang, JY; Jeong, SW; Jung, HJ; Kim, BS; Kim, HS; Kim, SG; Kim, YS; Lee, SH; Lee, YN | 1 |
Chen, DS; Hsu, CS; Hsu, SJ; Kao, JH; Lin, HH; Tseng, TC; Wang, CC | 1 |
Aldámiz-Echevarria, T; Berenguer, J; Carrero, A; Diez, C; García-Alvarez, M; García-Broncano, P; Guzmán-Fulgencio, M; Jiménez-Sousa, MA; Pineda-Tenor, D; Resino, S; Tejerina, F; Vázquez-Morón, S | 1 |
Abd El-Wahab, EW; Mikheal, A; Shatat, HZ; Sidkey, F | 1 |
Chang, JJ; Chien, CH; Chien, RN; Hu, CC; Lin, CL | 1 |
Ogawa, E | 1 |
Anzai, K; Eguchi, Y; Fujimoto, K; Iwane, S; Kawaguchi, Y; Kawazoe, S; Kuwashiro, T; Mizuta, T; Nakashita, S; Oeda, S; Otsuka, T; Oza, N; Ozaki, I; Takahashi, H | 1 |
Genné, D; Golay, A; Negro, F; Overbeck, K | 1 |
Chang, CY; Chang, FY; Chu, CJ; Hung, TH; Hwang, SJ; Lee, CY; Lee, FY; Lee, SD; Lin, HC; Lu, RH; Yang, PL; Yu, MI | 1 |
Abate, ML; Bo, S; Bugianesi, E; Cassader, M; Ciancio, A; Ciccone, G; Gambino, R; Giordanino, C; Olivero, A; Pellicano, R; Rizzetto, M; Saracco, G; Smedile, A | 1 |
Fehér, J; Hagymási, K | 1 |
Diago, M | 1 |
Elgouhari, HM; Feldstein, AE; Hanouneh, I; Zein, CO; Zein, NN | 1 |
Akiyama, T; Ario, K; Eguchi, Y; Hisatomi, A; Kawaguchi, Y; Kuwashiro, T; Mizuta, T; Otsuka, T; Oza, N; Ozaki, I; Takahashi, H; Yoshimura, T | 1 |
Alberti, A | 1 |
de los Santos-Gil, I; del Valle, J; Fernández-Fuertes, E; González-Serrano, M; Macías, J; Merchante, N; Merino, D; Mira, JA; Moro, A; Pineda, JA; Ruiz-Morales, J; Sanz-Sanz, J | 1 |
Chang, WY; Chen, SC; Chuang, WL; Dai, CY; Hou, NJ; Hsieh, MY; Huang, JF; Lin, ZY; Wang, LY; Yu, ML | 1 |
Cammà, C; Petta, S | 1 |
Blum, JS; Daniel, AL; Houlihan, JL; Walsh, JP | 1 |
Bain, VG; Neumann, AU; Patel, K; Pulkstenis, E; Subramanian, GM; Yoshida, EM | 1 |
Akuta, N; Arase, Y; Hirakawa, M; Hosaka, T; Ikeda, K; Kawamura, Y; Kobayashi, M; Kumada, H; Saitoh, S; Sezaki, H; Suzuki, F; Suzuki, Y; Yatsuji, H | 1 |
Fartoux, L; Poupon, R; Serfaty, L | 1 |
Bedossa, P; Boyer, N; Cardoso, AC; Marcellin, P; Martinot-Peignoux, M; Maylin, S; Moucari, R; Nicolas-Chanoine, MH; Ripault, MP; Stern, C; Valla, D; Vidaud, M; Voitot, H | 1 |
Anselmo, M; De Leo, P; Fabris, P; Grasso, A; Malfatti, F; Martines, H; Menardo, G; Toscanini, F | 1 |
Adorni, F; Antinori, S; Caramma, I; Cesari, M; Galli, M; Milazzo, L | 1 |
Bédossa, P; Cacoub, P; Carrat, F; Halfon, P; Lambert, J; Pénaranda, G; Pol, S | 1 |
Andrade, RJ; Calleja, JL; De la Mata, M; Diago, M; Durán, S; Fernández-Rodríguez, CM; García-Samaniego, J; Herrerías, JM; Moreno-Otero, R; Nuñez, O; Olveira, A; Planas, R; Romero-Gómez, M; Salmerón, J; Solà, R | 1 |
Alberti, A; Bonisegna, S; Bortoletto, G; Franceschini, L; Marcolongo, M; Martines, D; Mirandola, S; Noventa, F; Plebani, M; Realdon, S; Scribano, L | 1 |
Abdelaleem, A; Atef, R; Emad, M; Eslam, M; Hamdy, L; Khattab, M; Shaker, Y | 1 |
Imeryuz, N; Yilmaz, Y; Yonal, O | 1 |
Chuang, WL; Wu, KT; Yang, JF; Yu, ML | 1 |
Cingolani, A; De Luca, A; Donato, C; Pinnetti, C | 1 |
Christofi, M; Chung, RT; Delgado-Borrego, A; Healey, D; Jordan, SH; Kamegaya, Y; Lin, W; Lok, AS; Ludwig, DA; Negre, B | 1 |
Ali, A; Eslam, M; Hamdy, L; Khattab, M; Sharwae, MA; Shatat, M | 1 |
Berenguer, J; Catalán, P; Cosín, J; Gutiérrez, I; López, JC; Miralles, P; Moreno, S; Ramírez, M; Resino, S; Ryan, P | 1 |
Furusyo, N; Hayashi, J | 1 |
Belotti, C; Brocco, G; Bruno, R; Covolo, L; Cristofori, C; Donato, F; Fattovich, G; Gaeta, GB; Guido, M; Minola, E; Negro, F; Pasino, M; Perini, E; Puoti, M; Raimondo, G; Rossi, L; Santantonio, T | 1 |
Branch, AD; Bräu, N; Dieterich, DT; Factor, SH; Fiel, MI; Rodriguez-Torres, M; Slim, J; Sterling, RK; Sulkowski, MS; Talal, AH; Vachon, ML | 1 |
Afdhal, N; Conjeevaram, HS; Everhart, JE; Hoofnagle, JH; Howell, CD; Wahed, AS | 1 |
Sanyal, AJ | 1 |
Jahan, S; Khaliq, S; Pervaiz, A | 1 |
De Vincentiis, L; Durante-Mangoni, E; Iossa, D; Pinto, D; Ragone, E; Utili, R | 1 |
Duarte-Rojo, A; Feld, JJ; Heathcote, EJ | 1 |
Abdurakhmanov, DT; Baĭzhanova, ZhZh; Ignatova, TM; Nekrasova, TP | 1 |
Aparcero, R; Del Campo, JA; Eslam, M; Kawaguchi, T; Khattab, MA; Romero-Gomez, M; Sata, M | 1 |
Cabibi, D; Cammà, C; Craxì, A; Di Marco, V; Di Stefano, R; Marchesini, G; Petta, S | 1 |
Deltenre, P; Fartoux, L; Henrion, J; Lemoine, M; Louvet, A; Mathurin, P; Moreno, C; Mourad, A; Serfaty, L | 1 |
Chen, SC; Chuang, WL; Dai, CY; Hou, NJ; Hsiao, PJ; Huang, CF; Huang, CI; Huang, JF; Lin, ZY; Shin, SJ; Yang, JF; Yeh, ML; Yu, ML | 1 |
Eslam, M; López-Cortés, LF; Romero-Gomez, M | 1 |
Ando, K; Fujinami, A; Fukuda, K; Hasegawa, Y; Hayashi, Y; Hotta, H; Imoto, S; Kim, KI; Kim, SR; Komaki, T; Kudo, M; Maekawa, Y; Nagata, Y; Nakajima, T; Ohta, M; Ohtani, A; Otono, Y; Saito, J; Sugimoto, K | 1 |
Baroni, GS; Covolo, L; Faraci, MG; Fattovich, G; Guido, M; Ieluzzi, D; Negro, F; Pasino, M; Passigato, N; Pierantonelli, I; Tonon, A | 1 |
Ali, A; Aparcero, R; Del Campo, JA; Eslam, M; Grande, L; Khattab, MA; Mousa, YI; Romero-Gomez, M; Shaker, Y | 1 |
Hamzeh, FM; Han, J; Harrison, SA; Pandya, PK; Sheikh, MY; Vierling, JM | 1 |
Beumont, M; Carosi, G; DeMasi, R; Drenth, JP; Ferenci, P; Forns, X; Goeser, T; Lonjon-Domanec, I; Marcellin, P; Nevens, F; Picchio, G; Serfaty, L | 1 |
La Mura, V; Persico, M | 1 |
Ayala, CE; Bacchetti, P; Brandman, D; Khalili, M; Maher, JJ | 1 |
Petta, S | 1 |
Abd-Aalhalim, H; Aly, H; Eslam, M; Khattab, MA; Mousa, YI; Samir, F; Shaker, O; Shaker, Y; Shatat, M | 1 |
Kang, P; Sun, LJ; Yan, BZ; Yu, JW; Zhao, YH | 1 |
García-Ruiz, I; Gómez-Izquierdo, E; Muñoz-Yagüe, MT; Solís-Herruzo, JA; Solís-Muñoz, P; Valverde, AM | 1 |
Andersen, JW; Butt, AA; Chung, RT; Sherman, KE; Umbleja, T | 1 |
Furusyo, N; Hayashi, J; Hayashi, T; Ihara, T; Ikezaki, H; Kainuma, M; Murata, M; Ogawa, E; Okada, K; Taniai, H; Toyoda, K | 1 |
Aghemo, A; Colombo, M; D'Ambrosio, R; De Nicola, S; Degasperi, E; Grancini, V; Orsi, E; Prati, GM; Rumi, MG; Soffredini, R | 1 |
El Saadany, S; Enaba, M; Ghazy, M; Hasan, A; Ziada, DH | 1 |
Ampuero, J; Conde, M; Del Campo, JA; García-Lozano, JR; García-Valdecasas, M; González-Escribano, MF; Maraver, M; Millán, R; Rojas, A; Rojas, L; Romero-Gómez, M | 1 |
Chuang, WL; Dai, CY; Huang, JF; Yu, ML | 1 |
Andrade, RJ; Castillo, J; Corpas, R; Cruz, M; Del Mar Viloria, M; Diago, M; Fernández-Rodríguez, CM; Gila, A; Grande, L; Gutiérrez, ML; López-Serrano, P; Muñoz-De-Rueda, P; Pérez, C; Romero-Gómez, M; Ruiz-Extremera, A; Salmerón, J; Suárez, E; Vázquez, L | 1 |
D'Souza, R; Foster, GR; Sabin, CA | 1 |
Clouston, AD; Jonsson, JR; Lipka, GM; Powell, EE; Purdie, DM; Richardson, MM; Walsh, MJ | 1 |
Gui Qiang, W; Jian Wu, Y; Shu Chen, L | 1 |
Ariello, M; Conca, P; Mastrolia, M; Tarantino, G | 1 |
Araújo, C; Braga, H; Cruz, M; Cruz, T; Cunha, S; Mello, V; Ney-Oliveira, F; Nuñez, G; Parana, R; Schinoni, MI; Simões, MT | 1 |
Romero-Gómez, M | 1 |
Afdhal, NH; Conjeevaram, HS; Everhart, JE; Hoofnagle, JH; Kleiner, DE; Wahed, AS; Zacks, S | 1 |
Assy, N; Embon, O | 1 |
Almasio, PL; Amato, M; Craxí, A; De Lisi, S; Di Marco, V; Ferraro, D; Giordano, C; Lo Iacono, O; Mineo, C; Petta, S; Rodolico, V; Venezia, G | 1 |
Capasso, M; Crocè, L; Iolascon, A; La Mura, V; Masutti, F; Moschella, F; Persico, E; Persico, M; Russo, R; Spano, D; Svelto, M; Tiribelli, C; Torella, R | 1 |
Brandt, LR; Cua, IH; George, J; Hui, J; Kench, JG; Negro, F; Poustchi, H | 1 |
Bergamaschi, V; Borghi, F; Carosi, G; Cologni, G; Gatti, F; Matti, A; Nasta, P; Puoti, M; Ricci, A | 1 |
11 review(s) available for ribavirin and Insulin Sensitivity
Article | Year |
---|---|
[Clinical Implication of Insulin Resistance in Chronic Hepatitis C Patients].
Topics: Antiviral Agents; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferons; Ribavirin; Treatment Outcome | 2015 |
[Treatment of hepatitis C virus infection: current status and perspectives].
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Failure; Viral Load; Viremia | 2008 |
What are the comorbidities influencing the management of patients and the response to therapy in chronic hepatitis C?
Topics: Alcoholism; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Hepatitis B; Hepatitis C, Chronic; HIV Infections; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Metabolic Syndrome; Polyethylene Glycols; Recombinant Proteins; Ribavirin | 2009 |
Type B insulin resistance developing during interferon-alpha therapy.
Topics: Autoantibodies; Hepatitis C; Humans; Hyperglycemia; Immunoprecipitation; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Receptor, Insulin; Ribavirin | 2009 |
[Epidemiological and clinical study for hepatitis C virus infection].
Topics: Antiviral Agents; Drug Therapy, Combination; Hepacivirus; Hepatitis C; HTLV-I Infections; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Japan; Liver Neoplasms; Polyethylene Glycols; Recombinant Proteins; Renal Dialysis; Ribavirin | 2010 |
Sequence variability of HCV Core region: important predictors of HCV induced pathogenesis and viral production.
Topics: Carcinoma, Hepatocellular; Cell Cycle; Drug Therapy, Combination; Fatty Liver; Genetic Variation; Hepacivirus; Hepatitis C Antigens; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferons; Liver Neoplasms; Ribavirin; Viral Core Proteins; Virus Replication | 2011 |
'Easy to treat' genotypes were not created equal: can rapid virological response (RVR) level the playing field?
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Fatty Liver; Genotype; Hepacivirus; Hepatitis C, Chronic; Host-Pathogen Interactions; Humans; Insulin Resistance; Interferon Type I; Ribavirin; RNA, Viral; Treatment Outcome | 2011 |
Meta-analysis: insulin resistance and sustained virological response in hepatitis C.
Topics: Antiviral Agents; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Homeostasis; Humans; Insulin Resistance; Interferon-alpha; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Statistics as Topic; Treatment Outcome; Viral Load | 2011 |
Impact of insulin resistance on sustained response in HCV patients treated with pegylated interferon and ribavirin: a meta-analysis.
Topics: Antiviral Agents; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Polyethylene Glycols; Ribavirin; Treatment Outcome; Viral Load | 2011 |
The role of insulin resistance in HIV/hepatitis C virus-coinfected patients.
Topics: Antiretroviral Therapy, Highly Active; Antiviral Agents; Clinical Trials as Topic; Coinfection; Drug Therapy, Combination; Hepacivirus; Hepatitis C; HIV Infections; HIV-1; Humans; Insulin Resistance; Interferon-alpha; Polyethylene Glycols; Ribavirin; RNA, Viral; Treatment Outcome | 2011 |
Glucose abnormalities in hepatitis C virus infection.
Topics: Adult; Antiviral Agents; Diabetes Mellitus, Type 2; Disease Progression; Female; Glucose; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Ribavirin | 2013 |
21 trial(s) available for ribavirin and Insulin Sensitivity
Article | Year |
---|---|
Hepatitis C Direct Acting Antivirals and Ribavirin Modify Lipid but not Glucose Parameters.
Topics: Antiviral Agents; Apolipoproteins; Fatty Liver; Female; Glucose; Hepacivirus; Hepatitis C, Chronic; Homeostasis; Humans; Insulin Resistance; Lipids; Liver; Male; Middle Aged; Ribavirin; Treatment Outcome | 2019 |
Homeostasis model assessment of insulin resistance does not seem to predict response to telaprevir in chronic hepatitis C in the REALIZE trial.
Topics: Adult; Aged; Female; Hepatitis C, Chronic; Homeostasis; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Models, Biological; Oligopeptides; Polyethylene Glycols; Recombinant Proteins; Regression Analysis; Ribavirin; RNA, Viral; Treatment Failure; Treatment Outcome | 2013 |
Pilot study of pioglitazone before HCV retreatment in HIV/HCV genotype 1-infected subjects with insulin resistance and previous nonresponse to peginterferon and ribavirin therapy: A5239.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Pilot Projects; Pioglitazone; Retreatment; Ribavirin; RNA, Viral; Thiazolidinediones; Treatment Failure; Treatment Outcome; Viral Load | 2014 |
A pilot study of add-on oral hypoglycemic agents in treatment-naïve genotype-1 chronic hepatitis C patients receiving peginterferon alfa-2b plus ribavirin.
Topics: Acarbose; Adult; Aged; Antiviral Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Hypoglycemic Agents; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Metformin; Middle Aged; Pilot Projects; Pioglitazone; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Ribavirin; Sex Factors; Thiazolidinediones; Viral Load | 2014 |
Impact of Body Weight Reduction via Diet and Exercise on the Anti-Viral Effects of Pegylated Interferon Plus Ribavirin in Chronic Hepatitis C Patients with Insulin Resistance: A Randomized Controlled Pilot Trial.
Topics: Adult; Antiviral Agents; Body Weight; Diet; Directive Counseling; Drug Therapy, Combination; Exercise; Female; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Obesity; Pilot Projects; Prospective Studies; Ribavirin; Treatment Outcome; Viral Load; Weight Loss | 2015 |
Pioglitazone in chronic hepatitis C not responding to pegylated interferon-alpha and ribavirin.
Topics: Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Hypoglycemic Agents; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Pioglitazone; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Thiazolidinediones | 2008 |
Incidence of type 2 diabetes mellitus and glucose abnormalities in patients with chronic hepatitis C infection by response to treatment: results of a cohort study.
Topics: Adult; Antiviral Agents; Blood Glucose; Diabetes Mellitus, Type 2; Drug Carriers; Female; Follow-Up Studies; Glucose Intolerance; Glucose Tolerance Test; Hepacivirus; Hepatitis C Antibodies; Hepatitis C, Chronic; Humans; Incidence; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Italy; Male; Middle Aged; Polyethylene Glycols; Polymerase Chain Reaction; Prognosis; Recombinant Proteins; Retrospective Studies; Ribavirin; Risk Factors; RNA, Viral; Time Factors | 2008 |
Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Time Factors; Treatment Outcome; Viral Load; Young Adult | 2009 |
Treatment of insulin resistance with metformin in naïve genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin.
Topics: Adult; Antiviral Agents; Double-Blind Method; Drug Therapy, Combination; Female; Genotype; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Metformin; Middle Aged; Polyethylene Glycols; PPAR gamma; Recombinant Proteins; Ribavirin | 2009 |
Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance.
Topics: Adult; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Hypoglycemic Agents; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Pioglitazone; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Thiazolidinediones; Young Adult | 2010 |
Insulin resistance predicts re-treatment failure in an efficacy study of peginterferon-α-2a and ribavirin in HIV/HCV co-infected patients.
Topics: Adult; Antiviral Agents; Case-Control Studies; Female; Hepatitis C, Chronic; HIV Infections; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Liver; Male; Middle Aged; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Ribavirin; RNA, Viral; Treatment Failure | 2011 |
Insulin resistance impairs viral dynamics independently of ethnicity or genotypes.
Topics: Adult; Antiviral Agents; Black People; Drug Therapy, Combination; Egypt; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Hospitals, University; Humans; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Ribavirin; Spain; Treatment Outcome; Viral Load; White People | 2012 |
Chronic hepatitis C genotype 1 patients with insulin resistance treated with pioglitazone and peginterferon alpha-2a plus ribavirin.
Topics: Adult; Antiviral Agents; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Hypoglycemic Agents; Insulin Resistance; Interferon-alpha; Liver Cirrhosis; Male; Middle Aged; Pioglitazone; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Risk Factors; Thiazolidinediones; Treatment Outcome | 2012 |
Insulin resistance and response to telaprevir plus peginterferon α and ribavirin in treatment-naive patients infected with HCV genotype 1.
Topics: Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Administration Schedule; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Logistic Models; Male; Middle Aged; Multivariate Analysis; Oligopeptides; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Ribavirin; Treatment Outcome; Viral Load; Young Adult | 2012 |
Impact of insulin resistance on HCV treatment response and impact of HCV treatment on insulin sensitivity using direct measurements of insulin action.
Topics: Adolescent; Adult; Antiviral Agents; Female; Glucose; Hepacivirus; Hepatitis C; Humans; Insulin Resistance; Interferons; Male; Middle Aged; Ribavirin; Treatment Outcome; Young Adult | 2012 |
Changes in adipocytokines and insulin sensitivity during and after antiviral therapy for hepatitis C genotype 4.
Topics: Adipokines; Adult; Antiviral Agents; Biomarkers; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Logistic Models; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Outcome; Tumor Necrosis Factor-alpha; Viral Load | 2012 |
The effect of metformin on the efficacy of antiviral therapy in patients with genotype 1 chronic hepatitis C and insulin resistance.
Topics: Adult; Antibodies, Viral; Antiviral Agents; Drug Interactions; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Genotype; Hepatitis C; Hepatitis C, Chronic; Humans; Hypoglycemic Agents; Insulin Resistance; Interferon-alpha; Male; Metformin; Middle Aged; Multivariate Analysis; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Treatment Outcome | 2012 |
Impact of peginterferon alpha and ribavirin treatment on lipid profiles and insulin resistance in Hepatitis C virus/HIV-coinfected persons: the AIDS Clinical Trials Group A5178 Study.
Topics: Adult; Analysis of Variance; Antiviral Agents; Coinfection; Female; Hepatitis C; HIV Infections; Humans; Insulin Resistance; Interferon-alpha; Lipid Metabolism; Lipoproteins; Logistic Models; Male; Middle Aged; Polyethylene Glycols; Prospective Studies; Ribavirin | 2012 |
Sustained virological response prevents the development of insulin resistance in patients with chronic hepatitis C.
Topics: Adult; Antiviral Agents; Body Mass Index; Confidence Intervals; Drug Therapy, Combination; Female; Follow-Up Studies; Hepacivirus; Hepatitis C, Chronic; Homeostasis; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Models, Biological; Odds Ratio; Polyethylene Glycols; Recombinant Proteins; Recurrence; Ribavirin; Treatment Failure; Viral Load | 2012 |
Effects of fatty liver and related factors on the efficacy of combination antiviral therapy in patients with chronic hepatitis C.
Topics: Adult; Antiviral Agents; China; Drug Therapy, Combination; Fatty Liver; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Injections, Subcutaneous; Insulin; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Ultrasonography | 2006 |
Peripheral insulin resistance during treatment of chronic hepatitis C with peguilated interferon plus ribavirin.
Topics: Adult; Female; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin | 2006 |
60 other study(ies) available for ribavirin and Insulin Sensitivity
Article | Year |
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The impact of direct-acting antiviral treatment on lipid metabolism and insulin resistance in chronic hepatitis C patients: temporary? permanent?
Topics: Aged; Anilides; Antiviral Agents; Benzimidazoles; Blood Glucose; Cholesterol; Cyclopropanes; Drug Therapy, Combination; Female; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Lactams, Macrocyclic; Lipid Metabolism; Lipoproteins, LDL; Male; Middle Aged; Proline; Ribavirin; Ritonavir; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Triglycerides; Valine | 2020 |
A decrease in hepatitis C virus RNA to undetectable levels in chronic hepatitis C patients after PegIFNα + RVB or sofosbuvir + NS5A inhibitor treatment is associated with decreased insulin resistance and persistent oxidative stress.
Topics: Adult; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Oxidative Stress; Pilot Projects; Ribavirin; RNA, Viral; Sofosbuvir; Sustained Virologic Response; Treatment Outcome; Viral Nonstructural Proteins | 2020 |
Improvement of glycemic state among responders to Sofosbuvir-based treatment regimens: Single center experience.
Topics: Aged; Antiviral Agents; Blood Glucose; Diabetes Mellitus, Type 2; Egypt; Female; Glycated Hemoglobin; Glycemic Index; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Liver Cirrhosis; Male; Middle Aged; Retrospective Studies; Ribavirin; Sofosbuvir | 2017 |
Do we need to screen for de-novo diabetes mellitus in chronic hepatitis C patients after a sustained virological response?
Topics: Adult; Antiviral Agents; Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Insulin; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Leptin; Male; Middle Aged; Polyethylene Glycols; Predictive Value of Tests; Prospective Studies; Recombinant Proteins; Ribavirin; Risk Factors; Sustained Virologic Response; Time Factors; Treatment Outcome | 2017 |
Interferon-γ-inducible protein-10 in chronic hepatitis C: Correlations with insulin resistance, histological features & sustained virological response.
Topics: Adult; Aged; Antiviral Agents; Biopsy; Chemokine CXCL10; Enzyme-Linked Immunosorbent Assay; Fatty Liver; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-gamma; Liver; Male; Middle Aged; Ribavirin; Treatment Outcome; Viral Load | 2017 |
The association of hepatitis c virus infection status with serum glucose levels.
Topics: Adult; Antiviral Agents; Blood Glucose; Drug Therapy, Combination; Fasting; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Retrospective Studies; Ribavirin; Sustained Virologic Response | 2019 |
Adipokines and insulin resistance, predictors of response to therapy in Egyptian patients with chronic hepatitis C virus genotype 4.
Topics: Adipokines; Adiponectin; Adult; Antiviral Agents; Area Under Curve; Biomarkers; Biopsy; Body Mass Index; Chi-Square Distribution; Drug Therapy, Combination; Egypt; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Leptin; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Predictive Value of Tests; Ribavirin; Risk Factors; RNA, Viral; ROC Curve; Treatment Outcome; Viral Load | 2013 |
Sustained virological response following chronic hepatitis C treatment is associated with improvement in insulin resistance.
Topics: Adult; Antiviral Agents; Cohort Studies; Drug Therapy, Combination; Female; Follow-Up Studies; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Prospective Studies; Ribavirin; Treatment Outcome; Viral Load | 2013 |
Type 1 diabetes mellitus with dual autoimmune mechanism related to pegylated interferon and ribavirin treatment for chronic HCV hepatitis.
Topics: Antiviral Agents; Autoantibodies; Autoimmune Diseases; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Hashimoto Disease; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Islets of Langerhans; Male; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Vitiligo; Young Adult | 2013 |
Valuable antiviral therapeutic options for the treatment of chronic hepatitis C patients with thrombocytopenia.
Topics: Aged; Antiviral Agents; Cohort Studies; Female; Hemoglobins; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Interferons; Interleukins; Male; Middle Aged; Platelet Count; Polyethylene Glycols; Pyrophosphatases; Recombinant Proteins; Ribavirin; Thrombocytopenia; Treatment Outcome; Viral Load | 2013 |
The impact of pegylated interferon and ribavirin combination treatment on lipid metabolism and insulin resistance in chronic hepatitis C patients.
Topics: Adult; Aged; Antiviral Agents; Cholesterol; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Lipid Metabolism; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Outcome; Triglycerides | 2014 |
FTO rs9939609 polymorphism is associated with metabolic disturbances and response to HCV therapy in HIV/HCV-coinfected patients.
Topics: Adult; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Antiviral Agents; Body Mass Index; Coinfection; Cross-Sectional Studies; Female; Genetic Predisposition to Disease; Genotype; Hepatitis C, Chronic; HIV Infections; Humans; Insulin Resistance; Male; Metabolic Syndrome; Middle Aged; Obesity; Odds Ratio; Polymorphism, Single Nucleotide; Proteins; Ribavirin | 2014 |
Insulin resistance as a predictor of early virologic response to HCV therapy among chronic HCV Egyptian patients.
Topics: Adolescent; Adult; Antiviral Agents; Cross-Sectional Studies; Egypt; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Prognosis; Prospective Studies; Real-Time Polymerase Chain Reaction; Ribavirin; Treatment Outcome; Viral Load; Young Adult | 2015 |
Clearance of Hepatitis C Virus Improves Insulin Resistance During and After Peginterferon and Ribavirin Therapy.
Topics: Adult; Aged; Antiviral Agents; Body Weight; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; Humans; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Models, Biological; Ribavirin; Risk Factors; Treatment Outcome; Viral Load; Young Adult | 2015 |
Insulin resistance is a major determinant of sustained virological response in genotype 1 chronic hepatitis C patients receiving peginterferon alpha-2b plus ribavirin.
Topics: Antiviral Agents; Asian People; Cross-Sectional Studies; Drug Therapy, Combination; Female; Genotype; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Multivariate Analysis; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Ribavirin; Taiwan; Treatment Outcome; Viral Load | 2009 |
[Influence of weight reduction on the effectiveness of combined peginterferon and ribavirin treatment in chronic HCV hepatitis].
Topics: Amantadine; Antioxidants; Antiviral Agents; Drug Therapy, Combination; Fatty Liver; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Obesity; Polyethylene Glycols; Protective Agents; Recombinant Proteins; Ribavirin; Silymarin; Treatment Outcome; Weight Loss | 2008 |
Diabetes mellitus is associated with impaired response to antiviral therapy in chronic hepatitis C infection.
Topics: Adult; Antiviral Agents; Case-Control Studies; Diabetes Mellitus; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Hypoglycemic Agents; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Odds Ratio; Ohio; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Ribavirin; Risk Assessment; Risk Factors; RNA, Viral; Severity of Illness Index; Time Factors; Treatment Failure; Viral Load | 2009 |
Whole-body insulin sensitivity index is a highly specific predictive marker for virological response to peginterferon plus ribavirin therapy in chronic hepatitis C patients with genotype 1b and high viral load.
Topics: Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Glucose Tolerance Test; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin; Insulin Resistance; Insulin Secretion; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Predictive Value of Tests; Receptors, Tumor Necrosis Factor, Type II; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Viral Load | 2010 |
Insulin resistance is not a relevant predictor of sustained virological response to pegylated interferon plus ribavirin in HIV/HCV co-infected patients.
Topics: Adult; Antiviral Agents; Body Mass Index; Female; Hepacivirus; Hepatitis C; HIV Infections; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Retrospective Studies; Ribavirin; RNA, Viral; Treatment Outcome; Viral Load | 2009 |
Insulin resistance predicts response to peginterferon-alpha/ribavirin combination therapy in chronic hepatitis C patients.
Topics: Adult; Antiviral Agents; Drug Therapy, Combination; Female; Genotype; Hepatitis C, Chronic; Humans; Insulin Resistance; Insulin-Secreting Cells; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Regression Analysis; Ribavirin; RNA, Viral; Viral Load | 2009 |
Insulin resistance in HCV mono-infected and in HIV/HCV co-infected patients: Looking to the future.
Topics: Antiviral Agents; Diabetes Mellitus; Hepatitis C, Chronic; HIV Infections; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Predictive Value of Tests; Recombinant Proteins; Ribavirin; Risk Factors; Treatment Outcome; Viral Load | 2009 |
Early prediction of sustained virological response at day 3 of treatment with albinterferon-alpha-2b in patients with genotype 2/3 chronic hepatitis C.
Topics: Adult; Albumins; Antiviral Agents; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Recombinant Proteins; Ribavirin; RNA, Viral | 2009 |
Amino acid substitutions in the hepatitis C virus core region of genotype 1b are the important predictor of severe insulin resistance in patients without cirrhosis and diabetes mellitus.
Topics: Adult; Aged; Amino Acid Substitution; Antiviral Agents; Female; Hepacivirus; Hepatitis C; Humans; Insulin Resistance; Interferons; Japan; Male; Middle Aged; Ribavirin; Treatment Outcome; Viral Core Proteins; Young Adult | 2009 |
Pioglitazone as adjuvant therapy in chronic hepatitis C: sequential rather than concomitant administration with pegylated interferon and ribavirin?
Topics: Adult; Antiviral Agents; Chemotherapy, Adjuvant; Drug Administration Schedule; Hepatitis C, Chronic; Humans; Hypoglycemic Agents; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Pioglitazone; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Thiazolidinediones | 2009 |
Insulin resistance and geographical origin: major predictors of liver fibrosis and response to peginterferon and ribavirin in HCV-4.
Topics: Adult; Antiviral Agents; Black People; Egypt; Female; France; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Male; Middle Aged; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Ribavirin; RNA, Viral; Treatment Outcome | 2009 |
Impact of hyperglycaemia and cholesterol levels on the outcome of hepatitis C virus (HCV) treatment in HIV/HCV-coinfected patients.
Topics: Adult; Antiviral Agents; Blood Glucose; CD4 Lymphocyte Count; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; HIV Infections; Humans; Hypercholesterolemia; Hyperglycemia; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Lipodystrophy; Lipoproteins, LDL; Male; Middle Aged; Multivariate Analysis; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Ribavirin; Treatment Outcome; Triglycerides; Viral Load | 2009 |
Insulin resistance impairs sustained virological response rate to pegylated interferon plus ribavirin in HIV-hepatitis C virus-coinfected patients: HOMAVIC-ANRS HC02 Study.
Topics: Adult; Female; Genotype; Hepacivirus; Hepatitis C; HIV Infections; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin | 2009 |
Hyperinsulinaemia reduces the 24-h virological response to PEG-interferon therapy in patients with chronic hepatitis C and insulin resistance.
Topics: Adult; Antiviral Agents; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Hyperinsulinism; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Treatment Outcome; Viral Load | 2010 |
Metformin, hepatitis C, and insulin resistance: sufficient evidence?
Topics: Antiviral Agents; Female; Hepatitis C, Chronic; Humans; Hypoglycemic Agents; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Metformin; Polyethylene Glycols; Recombinant Proteins; Ribavirin | 2009 |
Insulin resistance predicts rapid virological response in non-diabetic, non-cirrhotic genotype 1 HCV patients treated with peginterferon alpha-2b plus ribavirin: some issues.
Topics: Antiviral Agents; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Prognosis; Recombinant Proteins; Ribavirin | 2010 |
Insulin resistance and HCV virologic response to peg-interferons (Peg-IFN) with ribavirin (RBV) in HIV/HCV co-infected patients.
Topics: Adult; Antiviral Agents; Female; Hepatitis C; HIV Infections; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Ribavirin; Treatment Outcome | 2010 |
Reduction of insulin resistance with effective clearance of hepatitis C infection: results from the HALT-C trial.
Topics: Adult; Aged; Female; Hepatitis C; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Longitudinal Studies; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Viral Load | 2010 |
Insulin resistance predicts rapid virologic response to peginterferon/ribavirin combination therapy in hepatitis C genotype 4 patients.
Topics: Adult; Antiviral Agents; Body Mass Index; Chi-Square Distribution; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Logistic Models; Male; Middle Aged; Odds Ratio; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Ribavirin; Statistics, Nonparametric; Treatment Outcome | 2010 |
Insulin resistance impairs response to interferon plus ribavirin in patients coinfected with HIV and hepatitis C virus.
Topics: Adult; Antiviral Agents; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; Hepatitis C; HIV Infections; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Liver; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Ribavirin; Viral Load | 2010 |
The homeostasis model assessment of the insulin resistance score is not predictive of a sustained virological response in chronic hepatitis C patients.
Topics: Adult; Antiviral Agents; Chi-Square Distribution; Drug Therapy, Combination; Female; Genotype; Health Status Indicators; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Italy; Logistic Models; Male; Middle Aged; Models, Biological; Polyethylene Glycols; Predictive Value of Tests; Prospective Studies; Recombinant Proteins; Ribavirin; Risk Assessment; Risk Factors; RNA, Viral; Time Factors; Treatment Outcome; Viral Load; White People | 2011 |
Changes in insulin sensitivity and body weight during and after peginterferon and ribavirin therapy for hepatitis C.
Topics: Adult; Age Factors; Antiviral Agents; Body Mass Index; Body Weight; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Multicenter Studies as Topic; Polyethylene Glycols; Recombinant Proteins; Ribavirin | 2011 |
Role of insulin resistance and hepatic steatosis in the progression of fibrosis and response to treatment in hepatitis C.
Topics: Antiviral Agents; Fatty Liver; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; MicroRNAs; Polyethylene Glycols; Recombinant Proteins; Ribavirin | 2011 |
Safety and efficacy of peginterferon alpha plus ribavirin in patients with chronic hepatitis C and coexisting heart disease.
Topics: Adult; Aged; Antiviral Agents; Disease Progression; Echocardiography; Electrocardiography; Female; Genotype; Heart Diseases; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Natriuretic Peptide, Brain; Peptide Fragments; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Outcome; Troponin I | 2011 |
[Metabolic syndrome in patients with chronic hepatitis C genotype 1].
Topics: Adult; Antiviral Agents; Fatty Liver; Female; Genome, Viral; Hepacivirus; Hepatitis C, Chronic; Hepatocytes; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Leptin; Liver Cirrhosis; Male; Metabolic Syndrome; Middle Aged; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Ribavirin; Severity of Illness Index; Treatment Outcome | 2011 |
TyG index, HOMA score and viral load in patients with chronic hepatitis C due to genotype 1.
Topics: Adult; Aged; Antiviral Agents; Blood Glucose; Body Mass Index; Drug Therapy, Combination; Fatty Liver; Female; Hepacivirus; Hepatitis C, Chronic; Homeostasis; Humans; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Treatment Outcome; Triglycerides; Viral Load | 2011 |
Pegylated interferon plus ribavirin therapy improves pancreatic β-cell function in chronic hepatitis C patients.
Topics: Adult; Antiviral Agents; Biomarkers; Blood Glucose; Chi-Square Distribution; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Interferon alpha-2; Interferon-alpha; Logistic Models; Male; Middle Aged; Odds Ratio; Polyethylene Glycols; Recombinant Proteins; Ribavirin; RNA, Viral; Taiwan; Time Factors; Treatment Outcome; Viral Load | 2011 |
Correlation between insulin resistance and outcome of pegylated interferon and ribavirin therapy, hepatic steatosis, hepatic fibrosis in chronic hepatitis C-1b and high viral load.
Topics: Aged; Antiviral Agents; Body Mass Index; Drug Therapy, Combination; Fatty Liver; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Outcome; Viral Load | 2011 |
Post-load insulin resistance does not predict virological response to treatment of chronic hepatitis C patients without the metabolic syndrome.
Topics: Antiviral Agents; Blood Glucose; Female; Ferritins; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Prospective Studies; Recombinant Proteins; Ribavirin; RNA | 2012 |
HCV infection, HOMA index and sustained virological response: the step we need to take before moving forward.
Topics: Antiviral Agents; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Ribavirin | 2012 |
Insulin resistance and diabetes mellitus in patients with chronic hepatitis C: spectators or actors?
Topics: Antiviral Agents; Diabetes Mellitus, Type 2; Female; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Male; Polyethylene Glycols; Recombinant Proteins; Ribavirin | 2012 |
Protein-tyrosine phosphatases are involved in interferon resistance associated with insulin resistance in HepG2 cells and obese mice.
Topics: Animals; Antiviral Agents; Enzyme Inhibitors; Gene Knockdown Techniques; Gene Silencing; Hep G2 Cells; Hepatitis C, Chronic; Humans; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Interferon-alpha; Male; Metformin; Mice; Mice, Obese; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Ribavirin; STAT1 Transcription Factor; Tumor Necrosis Factor-alpha; Vanadates | 2012 |
Insulin resistance undermines the advantages of IL28B polymorphism in the pegylated interferon alpha-2b and ribavirin treatment of chronic hepatitis C patients with genotype 1.
Topics: Aged; Antiviral Agents; Area Under Curve; Cohort Studies; Confidence Intervals; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Homeostasis; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Interferons; Interleukins; Male; Middle Aged; Models, Biological; Multivariate Analysis; Odds Ratio; Polyethylene Glycols; Polymorphism, Single Nucleotide; Recombinant Proteins; Ribavirin; ROC Curve; Treatment Outcome | 2012 |
The interaction between insulin resistance, liver fibrosis and early virological response in Egyptian patients with chronic hepatitis C.
Topics: Adult; Age Factors; Antiviral Agents; Biopsy; Chi-Square Distribution; Disease Progression; Drug Therapy, Combination; Egypt; Enzyme-Linked Immunosorbent Assay; Female; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon-alpha; Liver Cirrhosis; Logistic Models; Male; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Risk Factors; Severity of Illness Index; Viral Load | 2012 |
Insulin resistance predicts sustained virological response to treatment of chronic hepatitis C independently of the IL28b rs12979860 polymorphism.
Topics: Adult; Antiviral Agents; Blood Glucose; Cohort Studies; Drug Therapy, Combination; Female; Genotype; Genotyping Techniques; Hepatitis C, Chronic; Humans; Insulin; Insulin Resistance; Interferon-alpha; Interferons; Interleukins; Male; Middle Aged; Polyethylene Glycols; Polymorphism, Single Nucleotide; Recombinant Proteins; Regression Analysis; Ribavirin; Treatment Outcome; Viral Load | 2013 |
Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients.
Topics: Adult; Aged; Antiviral Agents; Cohort Studies; Drug Therapy, Combination; Female; Genotype; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Outcome; Viral Load; Viremia | 2005 |
Insulin resistance plays a significant role in liver fibrosis in chronic hepatitis C and in the response to antiviral therapy.
Topics: Adult; Antiviral Agents; Asian People; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Homeostasis; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Male; Middle Aged; Multivariate Analysis; Pilot Projects; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Outcome; White People | 2005 |
Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1.
Topics: Adult; Antiviral Agents; Drug Therapy, Combination; Fatty Liver; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Immunohistochemistry; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Liver; Male; Middle Aged; Obesity; Phosphoenolpyruvate Carboxykinase (GTP); Polyethylene Glycols; Recombinant Proteins; Retrospective Studies; Ribavirin; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Treatment Outcome | 2006 |
Does a lower insulin resistance affect antiviral therapy response in patients suffering from HCV related chronic hepatitis?
Topics: Adult; Aged; Antiviral Agents; Diet; Drug Therapy, Combination; Energy Intake; Female; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Outcome | 2006 |
Insulin resistance and hepatitis C.
Topics: Antiviral Agents; Hepatitis C, Chronic; Humans; Insulin; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Recombinant Proteins; Ribavirin | 2006 |
Race, insulin resistance and hepatic steatosis in chronic hepatitis C.
Topics: Adult; Antiviral Agents; Black or African American; Drug Therapy, Combination; Fatty Liver; Female; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Multivariate Analysis; Polyethylene Glycols; Prevalence; Prospective Studies; Recombinant Proteins; Ribavirin; Severity of Illness Index; Signal Transduction; White People | 2007 |
Peginterferon and ribavirin for hepatitis C.
Topics: Antiviral Agents; Disease Progression; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Risk Factors | 2007 |
The impact of insulin resistance, serum adipocytokines and visceral obesity on steatosis and fibrosis in patients with chronic hepatitis C.
Topics: Adipocytes; Adult; Antiviral Agents; Fatty Liver; Female; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Intra-Abdominal Fat; Liver Cirrhosis; Male; Middle Aged; Obesity; Recombinant Proteins; Ribavirin | 2007 |
Suppressor of cytokine signaling 3 (SOCS3) expression and hepatitis C virus-related chronic hepatitis: Insulin resistance and response to antiviral therapy.
Topics: Adult; Aged; Antiviral Agents; Biopsy; Cell Line; Cohort Studies; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Liver; Male; Metabolic Syndrome; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Treatment Outcome | 2007 |
Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3.
Topics: Adult; Aged; Antiviral Agents; Blood Glucose; Body Mass Index; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin; Insulin Resistance; Interferons; Liver; Liver Cirrhosis; Liver Function Tests; Logistic Models; Male; Middle Aged; Obesity; Ribavirin; Treatment Failure; Treatment Outcome | 2008 |
Insulin resistance impairs rapid virologic response in HIV/hepatitis C virus coinfected patients on peginterferon-alfa-2a.
Topics: Adult; Antiviral Agents; Blood Glucose; Drug Administration Schedule; Fasting; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV; HIV Infections; Homeostasis; Humans; Insulin; Insulin Resistance; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Multivariate Analysis; Polyethylene Glycols; Polymerase Chain Reaction; Recombinant Proteins; Ribavirin; RNA, Viral; Treatment Outcome; Viral Load | 2008 |