ribavirin has been researched along with Genetic Predisposition in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (10.64) | 29.6817 |
| 2010's | 41 (87.23) | 24.3611 |
| 2020's | 1 (2.13) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Tawashi, AS; Alaa, AM; Awwad, MA; El-Derany, MO; Eltobgy, MM; Gharib, MM; Kasem, MH; Mostafa, AM; Moubarak, AS; Omar, HM; Saafan, HA | 1 |
| Chen, M; Fan, H; Huang, P; Liu, M; Wang, J; Yao, Y; Yu, R; Yue, M; Zang, F | 1 |
| Deng, XZ; Ding, WL; Li, GT; Wang, LJ; Xiao, W; Zhang, GQ; Zhang, JH; Zhou, ZX; Zhu, DY; Zhu, YM | 1 |
| Feng, L; Gong, F; Hu, S; Huang, H; Sun, B; Yuan, F; Zheng, F | 1 |
| Barnes, E; Bucci, C; Christian, A; Collier, J; Flemming, VM; Halliday, J; Harrison, A; Irving, W; Klenerman, P; Manganis, C; von Delft, A | 1 |
| Mazana, JS | 1 |
| Aboalam, H; Ahmed, WH; Eldin, AS; Furusyo, N; Hayashi, J; Murata, M; Ogawa, E; Zaky, S | 1 |
| Capuron, L; de la Torre, R; Giménez, D; Gratacòs, M; Langohr, K; Martín-Santos, R; Moreno-España, J; Navinés, R; Solà, R; Udina, M | 1 |
| Fontana, RJ; Rangnekar, AS | 1 |
| Hsu, YA; Hung, DZ; Liao, WL; Lim, YP; Lin, CY; Peng, CY; Tien, N; Tsai, FJ; Tsai, KH; Wan, L | 1 |
| Asahina, Y; Enomoto, N; Hosokawa, T; Itakura, J; Izumi, N; Kakinuma, S; Kurosaki, M; Muraoka, M; Nakagawa, M; Nakanishi, H; Nishimura, T; Suzuki, Y; Takahashi, Y; Tamaki, N; Tsuchiya, K; Ueda, K; Watanabe, M; Yasui, Y | 1 |
| Cai, QX; Hong, CX; Lin, CS; Zhang, XH; Zhao, ZX | 1 |
| Aparicio, E; Clotet, B; Franco, S; Martinez, MA; Parera, M; Tural, C | 1 |
| Ackefors, M; Gjertsen, H; Nyström, J; Sönnerborg, A; Weiland, O; Wernerson, A | 1 |
| Brandão-Mello, CE; de Araújo Ramos, AL; de França, PH; de Jesus Dominici, A; de Mattos, AA; de Souza Leite Pinho, M; Ferreira, LE; Garcia, CE; Garcia, RF; Moreira, S; Nader, LA; Ramos, JA; Rondinelli, E; Tovo, CV; Villela-Nogueira, CA | 1 |
| Bon, D; Herrmann, E; Kottilil, S; Masur, H; Meissner, EG; O'Brien, TR; Osinusi, A; Prokunina-Olsson, L; Tang, W | 1 |
| Choudhuri, G; Khan, AJ; Mohindra, S; Negi, TS; Parmar, D; Saraswat, VA | 1 |
| Abe, H; Chayama, K; Hayashida, Y; Hayes, CN; Kubo, M; Miki, D; Ochi, H | 1 |
| Bonfim Freitas, F; da Silva Conde, SR; da Silva Graça, E; de Almeida Lins, PA; Demachki, S; Ferreira de Araújo, MT; Fonseca Filgueiras, NK; Ishak, R; Rosário Vallinoto, AC; Silva Dos Santos, BT; Soares Monteiro, JC | 1 |
| Blanchard, E; Samaras, K; Vickers, CR | 1 |
| Aldámiz-Echevarria, T; Berenguer, J; Carrero, A; Diez, C; García-Alvarez, M; García-Broncano, P; Guzmán-Fulgencio, M; Jiménez-Sousa, MA; Pineda-Tenor, D; Resino, S; Tejerina, F; Vázquez-Morón, S | 1 |
| Chang, KC; Chen, CH; Chen, HH; Hu, TH; Huang, CC; Huang, CM; Hung, HC; Lee, CM; Lin, MT; Lu, SN; Tsai, MC; Tseng, PL; Wang, JH; Wu, CK; Wu, YY; Yen, YH | 1 |
| Marqués-Lespier, J; Miranda-Avalo, EI; Morales-Vásquez, L; Muñoz-Acabá, J; Pastrana, R; Pérez-Cardona, CM; Quiñones-Badillo, Y; Rodríguez-Medina, JR; Torres, EA; Yamamura, Y | 1 |
| Antinori, S; Calvi, E; Cheli, S; Clementi, E; D'Avolio, A; De Nicolò, A; Falvella, FS; Magni, C; Mazzali, C; Milazzo, L; Peri, AM | 1 |
| Ampuero, J; Andrade, RJ; Buti, M; Cabezas, J; Calleja, JL; Crespo, J; Del Campo, JA; Fernández, I; Forns, X; Lens, S; Millán, R; Rojas, L; Romero-Gómez, M | 1 |
| Bura, M; Kowala-Piaskowska, AE; Kuśnierczyk, P; Mozer-Lisewska, I; Pauli, A; Piasecki, E; Rozpłochowski, B; Żeromski, J; Zwolińska, K | 1 |
| Artigas, F; Egmond, E; Gimenez, D; Gómez-Gil, E; Grande, I; Gratacós, M; Kapczinski, F; Langohr, K; Martín-Santos, R; Navinés, R; Oriolo, G; Solà, R; Udina, M; Valdés, M; Vieta, E | 1 |
| Chi, X; Gao, X; Jiang, J; Kong, F; Lv, J; Mei, R; Niu, J; Pan, Y; Sun, B; Sun, H; Wang, X; Wu, R; Xu, H; Yu, G; Zhong, J | 1 |
| Chen, YZ; Xie, X; Zhang, L | 1 |
| Abdel Ghany, HM; Abdelraheem, WM; Abdelwahab, SF; Abuloyoun, SM; Hassuna, NA; Rizk, HA | 1 |
| Frydecka, D; Małyszczak, K; Pawlak, D; Pawłowski, T | 1 |
| Fowell, AJ; Nash, KL | 1 |
| Clark, PJ; McHutchison, JG; Thompson, AJ | 1 |
| Blum, HE; Grimm, D; Thimme, R | 1 |
| Chen, DS; Chen, HC; Chen, PJ; Hsu, CS; Hsu, SJ; Jeng, J; Kao, JH; Lai, MY; Liu, CH; Liu, CJ; Niu, WF; Tseng, TC | 1 |
| Chang, SW; Chen, JY; Huang, CH; Huang, CW; Jeng, WJ; Lin, CY; Lin, TN; Sheen, IS | 1 |
| Abdullah, NA; Amr, KS; El-Batae, HE; Elhosary, YA; Ezzat, WM; Raslan, HM | 1 |
| Bonkovsky, HL; Dienstag, JL; Fontana, RJ; Litman, HJ; Lok, AS; Sterling, RK; Su, G | 1 |
| Arizumi, T; Chung, H; Hagiwara, S; Hayaishi, S; Inoue, T; Kitai, S; Kudo, M; Minami, Y; Sakurai, T; Takita, M; Ueda, T; Ueshima, K; Yada, N | 1 |
| Thompson, AJ | 1 |
| Abe, H; Agata, R; Aizawa, Y; Fujise, K; Ika, M; Matsudaira, H; Nagatsuma, K; Namiki, Y; Shimada, N; Tada, N; Tsubota, A; Yoshizawa, K; Yumoto, Y | 1 |
| Baur, K; Geier, A; Rau, M | 1 |
| Carbone, A; Carella, C; Cioffi, M; Mazziotti, G; Morisco, F; Sorvillo, F | 1 |
| Ferenci, P; Gangl, A; Gasche, C; Grundtner, P; Hofer, H; Neufeld, JB; Oesterreicher, C; Wrba, F | 1 |
| Chao, YC; Chen, DS; Chen, EY; Chen, PJ; Chuang, WL; Dai, CY; Gu, ZJ; Hwang, Y; Lai, MY; Lee, CM; Liao, YT; Shian-Jy Bey, M; Wang, JH; Yu, ML | 1 |
| Arora, N; Goyal, A; Kumar, GT; Sarin, SK; Shukla, DK; Suneetha, PV | 1 |
| Arraes, LC; Crovella, S; Montenegro de Melo, F; Moura, P; Santos Silva, B; Segat, L; Silva Vasconcelos, LR | 1 |
7 review(s) available for ribavirin and Genetic Predisposition
| Article | Year |
|---|---|
[Interferon treatment of chronic hepatitis C: basic immunobiology and immunopathology of the liver].
Topics: Antiviral Agents; Drug Monitoring; Drug Therapy, Combination; Elasticity Imaging Techniques; Genetic Predisposition to Disease; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Spain; Treatment Outcome | 2013 |
IL-28B polymorphisms and the response to antiviral therapy in HCV genotype 2 and 3 varies by ethnicity: a meta-analysis.
Topics: Antiviral Agents; Asian People; Genetic Predisposition to Disease; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Interferons; Interleukins; Odds Ratio; Polyethylene Glycols; Polymorphism, Single Nucleotide; Publication Bias; Ribavirin; Time Factors; Treatment Outcome; White People | 2013 |
Association between IFNL4 rs368234815 polymorphism and sustained virological response in chronic hepatitis C patients undergoing PEGylated interferon/ribavirin therapy: A meta-analysis.
Topics: Antigens, Viral; Genetic Predisposition to Disease; Hepatitis C, Chronic; Humans; Immunity; Interferon-alpha; Interleukins; Polyethylene Glycols; Polymorphism, Single Nucleotide; Ribavirin; Treatment Outcome | 2016 |
Telaprevir: a new hope in the treatment of chronic hepatitis C?
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Synergism; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver Cirrhosis; Oligopeptides; Ribavirin; Serine Proteinase Inhibitors; Treatment Outcome | 2010 |
IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: the future of personalized HCV therapies.
Topics: Antiviral Agents; Female; Follow-Up Studies; Forecasting; Gene Expression Regulation, Viral; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Hepatitis C, Chronic; Humans; Interferons; Interleukins; Male; Polymorphism, Genetic; Precision Medicine; Randomized Controlled Trials as Topic; Ribavirin; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2011 |
[Genome-wide association studies].
Topics: Antiviral Agents; Chromosomes, Human, Pair 19; Genetic Markers; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Haplotypes; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Interleukins; Phenotype; Polyethylene Glycols; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Recombinant Proteins; Ribavirin | 2011 |
Host genetic variants in the pathogenesis of hepatitis C.
Topics: Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Disease Susceptibility; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C; Host-Pathogen Interactions; Humans; Interferons; Interleukins; Membrane Transport Proteins; Pyrophosphatases; Receptors, Calcitriol; Ribavirin; Treatment Outcome | 2012 |
4 trial(s) available for ribavirin and Genetic Predisposition
| Article | Year |
|---|---|
IFNL4-ΔG genotype is associated with slower viral clearance in hepatitis C, genotype-1 patients treated with sofosbuvir and ribavirin.
Topics: Antiviral Agents; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interleukins; Ribavirin; Sofosbuvir; Uridine Monophosphate | 2014 |
Association of IL28B gene variations with mathematical modeling of viral kinetics in chronic hepatitis C patients with IFN plus ribavirin therapy.
Topics: Antiviral Agents; Drug Therapy, Combination; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Interleukins; Kinetics; Models, Biological; Multivariate Analysis; Polyethylene Glycols; Polymorphism, Single Nucleotide; Recombinant Proteins; Ribavirin; Time Factors; Viral Load | 2011 |
YKL-40 genetic polymorphisms and the risk of liver disease progression in patients with advanced fibrosis due to chronic hepatitis C.
Topics: Adipokines; Adult; Chitinase-3-Like Protein 1; Disease Progression; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Hepatitis C, Chronic; Humans; Interferon-alpha; Lectins; Liver Cirrhosis; Male; Middle Aged; Polyethylene Glycols; Polymorphism, Genetic; Promoter Regions, Genetic; Recombinant Proteins; Ribavirin | 2012 |
Several factors including ITPA polymorphism influence ribavirin-induced anemia in chronic hepatitis C.
Topics: Aged; Anemia; Antiviral Agents; Biomarkers; Chi-Square Distribution; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Hemoglobins; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Japan; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Phenotype; Polyethylene Glycols; Polymorphism, Single Nucleotide; Pyrophosphatases; Recombinant Proteins; Ribavirin; Risk Assessment; Risk Factors | 2012 |
36 other study(ies) available for ribavirin and Genetic Predisposition
| Article | Year |
|---|---|
Interleukin-17 haplotyping predicts hepatocellular carcinoma in sofosbuvir, pegylated interferon-alpha-2a & ribavirin treated chronic hepatitis C patients.
Topics: alpha-Fetoproteins; Antiviral Agents; Carcinoma, Hepatocellular; Cohort Studies; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Haplotypes; Hepatitis C, Chronic; Humans; Interferon-alpha; Interleukin-17; Liver Neoplasms; Male; Middle Aged; Polyethylene Glycols; Polymorphism, Single Nucleotide; Receptors, Interleukin-17; Recombinant Proteins; Ribavirin; Sofosbuvir | 2021 |
The association of LMP7 and TAP2 gene polymorphisms with treatment response to interferon/ribavirin in patients with genotype 1 chronic hepatitis C.
Topics: Adult; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B, Member 3; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Polymorphism, Single Nucleotide; Proteasome Endopeptidase Complex; Ribavirin; Viral Load | 2017 |
Association of IL-28B, TBX21 gene polymorphisms and predictors of virological response for chronic hepatitis C.
Topics: Adolescent; Adult; Aged; Antibodies, Viral; Antiviral Agents; Asian People; China; Disease Susceptibility; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Interferons; Interleukins; Male; Middle Aged; Polyethylene Glycols; Polymorphism, Single Nucleotide; Ribavirin; Sustained Virologic Response; T-Box Domain Proteins; Viral Core Proteins; Young Adult | 2018 |
KIR2DL2/C1 is a Risk Factor for Chronic Infection and Associated with Non-response to PEG-IFN and RBV Combination Therapy in Hepatitis C Virus Genotype 1b Patients in China.
Topics: Adult; Antiviral Agents; China; Drug Therapy, Combination; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Polyethylene Glycols; Receptors, KIR2DL2; Ribavirin; Risk Factors; Treatment Outcome | 2018 |
'Favourable' IL28B polymorphisms are associated with a marked increase in baseline viral load in hepatitis C virus subtype 3a infection and do not predict a sustained virological response after 24 weeks of therapy.
Topics: Adult; Aged; Antiviral Agents; Cohort Studies; Female; Genetic Predisposition to Disease; Genotype; Hepacivirus; Hepatitis C; Humans; Interferons; Interleukins; Male; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Ribavirin; United Kingdom; Viral Load; Young Adult | 2013 |
Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for predicting anemia in Egyptian hepatitis C virus patients.
Topics: Adult; Anemia; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Egypt; Female; Gene Frequency; Genetic Predisposition to Disease; Hemoglobins; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Logistic Models; Male; Multivariate Analysis; Odds Ratio; Phenotype; Polyethylene Glycols; Polymorphism, Single Nucleotide; Pyrophosphatases; Recombinant Proteins; Ribavirin; Risk Factors; Time Factors; Treatment Outcome | 2013 |
Serotonin and interleukin-6: the role of genetic polymorphisms in IFN-induced neuropsychiatric symptoms.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Antiviral Agents; Anxiety; Cohort Studies; Depression; Drug Therapy, Combination; Fatigue; Genetic Predisposition to Disease; Hepatitis C, Chronic; Humans; INDEL Mutation; Interferon-alpha; Interleukin-6; Middle Aged; Point Mutation; Polyethylene Glycols; Promoter Regions, Genetic; Prospective Studies; Recombinant Proteins; Ribavirin; Serotonin; Serotonin Plasma Membrane Transport Proteins; White People | 2013 |
The impact of polymorphisms in STAT6 on treatment outcome in HCV infected Taiwanese Chinese.
Topics: Asian People; Drug Therapy, Combination; Female; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Linkage Disequilibrium; Logistic Models; Male; Middle Aged; Multivariate Analysis; Polyethylene Glycols; Polymorphism, Single Nucleotide; Recombinant Proteins; Ribavirin; STAT6 Transcription Factor; Taiwan; Treatment Outcome | 2013 |
Genetic variation near interleukin 28B and the risk of hepatocellular carcinoma in patients with chronic hepatitis C.
Topics: Adult; Aged; Alanine Transaminase; alpha-Fetoproteins; Antiviral Agents; Carcinoma, Hepatocellular; Cohort Studies; Disease Progression; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Genotype; Hepatitis C, Chronic; Humans; Interferon-alpha; Interferon-beta; Interferons; Interleukins; Liver Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Ribavirin | 2014 |
Prevalence of IL-28B and ITPA genotypes in Chinese Han population infected persistently with hepatitis C virus genotype 6 or HCV-1.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Asian People; China; Ethnicity; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Hemolysis; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Interleukins; Male; Middle Aged; Pyrophosphatases; Ribavirin; Young Adult | 2013 |
IFNL4 ss469415590 variant is a better predictor than rs12979860 of pegylated interferon-alpha/ribavirin therapy failure in hepatitis C virus/HIV-1 coinfected patients.
Topics: Adult; Antiviral Agents; Cohort Studies; Coinfection; Female; Genetic Predisposition to Disease; Genotype; Hepatitis C, Chronic; HIV Infections; Humans; Interferon-alpha; Interleukins; Male; Polymorphism, Genetic; Ribavirin; Treatment Failure | 2014 |
Evolution of fibrosis during HCV recurrence after liver transplantation--influence of IL-28B SNP and response to peg-IFN and ribavirin treatment.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Child; Female; Genetic Predisposition to Disease; Genotype; Hepatitis C, Chronic; Humans; Interferons; Interleukins; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Polymorphism, Single Nucleotide; Recurrence; Ribavirin; Severity of Illness Index; Young Adult | 2013 |
Interleukin 28B-related polymorphisms: a pathway for understanding hepatitis C virus infection?
Topics: Adult; Aged; Antiviral Agents; Brazil; Case-Control Studies; Drug Therapy, Combination; Female; Gene Frequency; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Interleukins; Linkage Disequilibrium; Male; Middle Aged; Phenotype; Polyethylene Glycols; Polymorphism, Single Nucleotide; Recombinant Proteins; Ribavirin; Time Factors; Treatment Outcome; Young Adult | 2013 |
Association of interleukin-10 polymorphisms with chronic hepatitis C virus infection in a case-control study and its effect on the response to combined pegylated interferon/ribavirin therapy.
Topics: Adult; Aged; Case-Control Studies; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Interleukin-10; Male; Middle Aged; Polymorphism, Genetic; Ribavirin; Treatment Outcome | 2015 |
IFNL4/IL-28B haplotype structure and its impact on susceptibility to hepatitis C virus and treatment response in the Japanese population.
Topics: Antiviral Agents; Asian People; Case-Control Studies; Drug Therapy, Combination; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Interleukins; Japan; Polyethylene Glycols; Polymorphism, Single Nucleotide; Recombinant Proteins; Ribavirin; Treatment Outcome | 2014 |
SNP rs8099917 in gene IL28B might be associated with risk of chronic infection by HCV but not with response to treatment.
Topics: Case-Control Studies; Female; Follow-Up Studies; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Interleukins; Male; Middle Aged; Polymorphism, Single Nucleotide; Ribavirin; Risk Factors; Treatment Outcome | 2014 |
Not so sweet: autoimmune diabetes mellitus on triple therapy for chronic hepatitis C infection.
Topics: Adult; Antiviral Agents; Autoimmune Diseases; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Hepatitis C, Chronic; Humans; Interferon-alpha; Interferons; Interleukins; Oligopeptides; Polyethylene Glycols; Polymorphism, Single Nucleotide; Proline; Protease Inhibitors; Ribavirin; Young Adult | 2015 |
FTO rs9939609 polymorphism is associated with metabolic disturbances and response to HCV therapy in HIV/HCV-coinfected patients.
Topics: Adult; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Antiviral Agents; Body Mass Index; Coinfection; Cross-Sectional Studies; Female; Genetic Predisposition to Disease; Genotype; Hepatitis C, Chronic; HIV Infections; Humans; Insulin Resistance; Male; Metabolic Syndrome; Middle Aged; Obesity; Odds Ratio; Polymorphism, Single Nucleotide; Proteins; Ribavirin | 2014 |
A polymorphism in interferon L3 is an independent risk factor for development of hepatocellular carcinoma after treatment of hepatitis C virus infection.
Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Carcinoma, Hepatocellular; Female; Genetic Predisposition to Disease; Hepatitis C, Chronic; Humans; Interferon-alpha; Interferons; Interleukins; Liver Neoplasms; Male; Middle Aged; Polymorphism, Single Nucleotide; Retrospective Studies; Ribavirin; Risk Factors; Taiwan; Young Adult | 2015 |
Demographics, clinical characteristics, IFNL3- and IFNL4- polymorphisms in a cohort of hepatitis C patients from Puerto Rico.
Topics: Adult; Aged; Alleles; Antiviral Agents; Ethnicity; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Hepatitis C; Humans; Interferons; Interleukins; Male; Middle Aged; Polyethylene Glycols; Polymorphism, Single Nucleotide; Puerto Rico; Recombinant Proteins; Registries; Ribavirin; Socioeconomic Factors | 2014 |
SLC29A1 polymorphism and prediction of anaemia severity in patients with chronic hepatitis C receiving triple therapy with telaprevir.
Topics: Anemia; Antiviral Agents; Drug Therapy, Combination; Equilibrative Nucleoside Transporter 1; Female; Genetic Predisposition to Disease; Genotype; Genotyping Techniques; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Oligopeptides; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Prospective Studies; Ribavirin | 2015 |
Role of ITPA and SLC28A2 genes in the prediction of anaemia associated with protease inhibitor plus ribavirin and peginterferon in hepatitis C treatment.
Topics: Adolescent; Adult; Aged; Anemia; Antiviral Agents; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Hepatitis C, Chronic; Humans; Incidence; Male; Membrane Transport Proteins; Middle Aged; Oligopeptides; Proline; Prospective Studies; Protease Inhibitors; Pyrophosphatases; Ribavirin; Risk Assessment; Young Adult | 2015 |
Genetic (KIR, HLA-C) and Some Clinical Parameters Influencing the Level of Liver Enzymes and Early Virologic Response in Patients with Chronic Hepatitis C.
Topics: Adult; Biomarkers, Pharmacological; Female; Genetic Association Studies; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C, Chronic; HLA-C Antigens; Humans; Immunity, Innate; Immunotherapy; Interferon-alpha; Killer Cells, Natural; Liver; Male; Middle Aged; Mutation; Polymorphism, Genetic; Receptors, KIR; Ribavirin | 2016 |
Glucocorticoid Receptors, Brain-Derived Neurotrophic Factor, Serotonin and Dopamine Neurotransmission are Associated with Interferon-Induced Depression.
Topics: Adult; Antiviral Agents; Brain-Derived Neurotrophic Factor; Catechol O-Methyltransferase; Depression; Female; Genetic Predisposition to Disease; Hepatitis C, Chronic; Humans; Incidence; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-alpha; Interferons; Interleukins; Male; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Receptor, Serotonin, 5-HT1A; Receptors, Glucocorticoid; Ribavirin; Tacrolimus Binding Proteins; Treatment Outcome; White People | 2016 |
Sustained viral response and treatment-induced cytopenia correlate with SLCs and KLF12 genotypes in interferon/ribavirin-treated Chinese chronic hepatitis C patients.
Topics: Adult; Anion Transport Proteins; Antiporters; Antiviral Agents; China; Drug Therapy, Combination; Equilibrative Nucleoside Transporter 1; Female; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Kruppel-Like Transcription Factors; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Pharmacogenomic Variants; Polyethylene Glycols; Polymorphism, Single Nucleotide; Recombinant Proteins; Retrospective Studies; Ribavirin; Risk Factors; Sustained Virologic Response; Thrombocytopenia; Time Factors; Treatment Outcome | 2016 |
Interleukin-10.rs1800896 and Interleukin-18.rs1946518 gene polymorphisms could not predict the outcome of hepatitis C virus infection in Egyptian patients treated with pegylated interferon plus ribavirin.
Topics: Adult; Antiviral Agents; Egypt; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Hepacivirus; Hepatitis C; Humans; Interferon-alpha; Interleukin-10; Interleukin-18; Male; Middle Aged; Mutation; Polyethylene Glycols; Polymorphism, Single Nucleotide; Recombinant Proteins; Ribavirin | 2016 |
Functional Polymorphism in the Interleukin 6 (IL6) Gene with Respect to Depression Induced in the Course of Interferon-α and Ribavirin Treatment in Chronic Hepatitis Patients.
Topics: Adult; Antiviral Agents; Cohort Studies; Depression; Female; Genetic Predisposition to Disease; Genotype; Hepatitis C, Chronic; Humans; Interferon-alpha; Interleukin-6; Longitudinal Studies; Male; Middle Aged; Poland; Polyethylene Glycols; Polymorphism, Genetic; Prevalence; Recombinant Proteins; Ribavirin | 2016 |
IL28B SNP rs12979860 is a critical predictor for on-treatment and sustained virologic response in patients with hepatitis C virus genotype-1 infection.
Topics: Adult; Female; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Interleukins; Linkage Disequilibrium; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Multivariate Analysis; Polyethylene Glycols; Polymorphism, Single Nucleotide; Prognosis; Recombinant Proteins; Ribavirin; Treatment Outcome; Viral Load | 2011 |
Possible role of angiotensin-converting enzyme polymorphism on progression of hepatic fibrosis in chronic hepatitis C virus infection.
Topics: Adult; Antiviral Agents; Disease Progression; Female; Genetic Predisposition to Disease; Genotype; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver Cirrhosis; Male; Peptidyl-Dipeptidase A; Polyethylene Glycols; Polymerase Chain Reaction; Polymorphism, Genetic; Recombinant Proteins; Ribavirin | 2011 |
Association of interleukin-28B and hepatitis C genotype 1 with a high viral load and response to pegylated interferon plus ribavirin therapy.
Topics: Adult; Aged; Antiviral Agents; Cohort Studies; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Genotype; Hepacivirus; Hepatitis C; Humans; Interferon alpha-2; Interferon-alpha; Interferons; Interleukins; Male; Middle Aged; Polyethylene Glycols; Polymorphism, Single Nucleotide; Recombinant Proteins; Retrospective Studies; Ribavirin; Risk Factors; RNA, Viral; Viral Load; Young Adult | 2011 |
Genetic factors and hepatitis C virus infection.
Topics: Antiviral Agents; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Hepatitis C, Chronic; Humans; Interferon-alpha; Interferons; Interleukins; Oligopeptides; Polyethylene Glycols; Polymorphism, Single Nucleotide; Predictive Value of Tests; Proline; Recombinant Proteins; Ribavirin; Risk Factors; Treatment Outcome | 2012 |
Is the IFN-alpha-related thyroid autoimmunity an immunologically heterogeneous disease?
Topics: Antiviral Agents; Autoimmune Diseases; Autoimmunity; Drug Therapy, Combination; Genetic Predisposition to Disease; Hepatitis C, Chronic; Humans; Interferon-alpha; Ribavirin; Thyroid Diseases; Thyroid Gland | 2002 |
Bi-allelic presence of the interleukin-10 receptor 1 G330R allele is associated with cirrhosis in chronic HCV-1 infection.
Topics: Adult; Aged; Amino Acid Substitution; Antiviral Agents; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C; Humans; Interferons; Liver Cirrhosis; Middle Aged; Receptors, Interleukin; Receptors, Interleukin-10; Ribavirin | 2005 |
Genetic predisposition of responsiveness to therapy for chronic hepatitis C.
Topics: Adult; Aged; Female; Genetic Predisposition to Disease; Haplotypes; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Polymorphism, Genetic; Retrospective Studies; Ribavirin | 2006 |
CCR5Delta32 mutation does not influence the susceptibility to HCV infection, severity of liver disease and response to therapy in patients with chronic hepatitis C.
Topics: Adult; Alanine Transaminase; Alleles; Antiviral Agents; Case-Control Studies; Disease Progression; Drug Therapy, Combination; Female; Genetic Predisposition to Disease; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Mutation; Polyethylene Glycols; Receptors, CCR5; Recombinant Proteins; Ribavirin; Severity of Illness Index | 2006 |
Association of polymorphisms in the first exon of mannose binding lectin gene (MBL2) in Brazilian patients with HCV infection.
Topics: Adult; Aged; Antiviral Agents; Brazil; Case-Control Studies; Disease Progression; Exons; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Mannose-Binding Lectin; Middle Aged; Polyethylene Glycols; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Recombinant Proteins; Ribavirin; Treatment Outcome | 2007 |