rhodotorulic-acid and Hypersensitivity

rhodotorulic-acid has been researched along with Hypersensitivity* in 1 studies

Other Studies

1 other study(ies) available for rhodotorulic-acid and Hypersensitivity

Article	Year
Synthesis and antiallergic activity of some quinolinones and imidazoquinolinones. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 A group of 1,4-dihydro-4-oxoquinoline-2- and -3-carboxylic acid esters with nitrogen functionality at the 8-position was synthesized, and 6-oxo-6H-imidazo[4,5,1-ij]quinoline-4- and -5-carboxylic acid esters were elaborated from these. Several of the compounds displayed activity in the rat passive cutaneous anaphylaxis (PCA) test for antiallergic activity. However, PCA activity in this series was accompanied by rat toxicity, as measured by a decrease in percent of normal weight gain over a 2-week period, following a single oral dose. Topics: Animals; Body Weight; Histamine H1 Antagonists; Hydroxamic Acids; Hypersensitivity; Imidazoles; Male; Piperazines; Quinolines; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1985

Article

Year

Synthesis and antiallergic activity of some quinolinones and imidazoquinolinones.

Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

A group of 1,4-dihydro-4-oxoquinoline-2- and -3-carboxylic acid esters with nitrogen functionality at the 8-position was synthesized, and 6-oxo-6H-imidazo[4,5,1-ij]quinoline-4- and -5-carboxylic acid esters were elaborated from these. Several of the compounds displayed activity in the rat passive cutaneous anaphylaxis (PCA) test for antiallergic activity. However, PCA activity in this series was accompanied by rat toxicity, as measured by a decrease in percent of normal weight gain over a 2-week period, following a single oral dose.

Topics: Animals; Body Weight; Histamine H1 Antagonists; Hydroxamic Acids; Hypersensitivity; Imidazoles; Male; Piperazines; Quinolines; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1985