rhodioloside and Disease Models, Animal

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Diabetic Cardiomyopathies; Disease Models, Animal; Glucosides; Inflammation; Male; Myocytes, Cardiac; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; TOR Serine-Threonine Kinases

Topics: Animals; Apoptosis; Biomarkers; Brain Ischemia; CA1 Region, Hippocampal; Cell Survival; Cells, Cultured; Disease Management; Disease Models, Animal; Fluorescent Antibody Technique; Glucosides; Immunohistochemistry; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Neuroprotection; Phenols; Rats

Topics: Acute Disease; Altitude Sickness; Animals; Brain; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mice; Mice, Inbred C57BL; PC12 Cells; Phenols; Rats; Rhodiola; Signal Transduction

Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Glucosides; Inflammation; Lung; Mice; Mice, Inbred BALB C; MicroRNAs; Ovalbumin; Phenols; Signal Transduction; Suppressor of Cytokine Signaling Proteins

Topics: Animals; Aortic Valve Stenosis; Cardiomegaly; Cells, Cultured; Disease Models, Animal; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Rats; Signal Transduction; Toll-Like Receptor 4

Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hormones; Lung; Metalloproteases; Mice; Mice, Inbred BALB C; Ovalbumin; Pyrimidines; Steroids

Topics: Animals; Diabetes Mellitus; Disease Models, Animal; Ferroptosis; Hindlimb; Hyperglycemia; Ischemia; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Neovascularization, Physiologic

Topics: Animals; Disease Models, Animal; Glucosides; Hippocampus; Humans; Phenols; Rats; Stress Disorders, Post-Traumatic

Topics: Animals; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Brain; Cell Line; Coculture Techniques; Complement Activation; Complement C3; Complement Inactivating Agents; Disease Models, Animal; Endothelial Cells; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Infarction, Middle Cerebral Artery; Inflammation Mediators; Male; Mice; Oxidative Stress; Phenols; Phenotype; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction

Topics: Animals; Antioxidants; Disease Models, Animal; Down-Regulation; Glucosides; Lung; Male; Muscle, Skeletal; Muscular Atrophy; Myogenin; Myostatin; Nicotiana; Phenols; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Rats; Rats, Wistar; Smoke; Smoking; Up-Regulation

Topics: Animals; Apoptosis; Cardiotonic Agents; Coronary Vessels; Cytokines; Disease Models, Animal; Fibrosis; Glucosides; Heart; Ligation; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; Phenols; Ventricular Remodeling

Topics: Animals; Bile Acids and Salts; Diet, High-Fat; Disease Models, Animal; Gastrointestinal Microbiome; Glucosides; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phenols; Receptors, Cytoplasmic and Nuclear; Triglycerides

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognitive Dysfunction; Disease Models, Animal; Glucosides; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Phenols; Phosphatidylinositol 3-Kinases; Signal Transduction; TOR Serine-Threonine Kinases

Topics: Animals; Asthma; Cytokines; Disease Models, Animal; Female; Glucosides; Humans; Hypersensitivity; Immunity, Innate; Immunosuppressive Agents; Interleukin-1 Receptor-Like 1 Protein; Interleukin-33; Lymphocytes; Mice; Mice, Inbred C57BL; Phenols; Pneumonia; Respiratory System; Rhodiola; Signal Transduction; Th2 Cells

Topics: Animals; Cartilage, Articular; Cell Proliferation; Chondrocytes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glucosides; Injections, Intraperitoneal; NF-kappa B; Osteoarthritis; Phenols; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

Topics: Animals; Disease Models, Animal; Glucosides; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Parkinson Disease; Phenols; Pyroptosis; Signal Transduction

Topics: Animals; Brain; Cognition; Dementia, Vascular; Disease Models, Animal; Glucosides; Male; Malondialdehyde; Maze Learning; Morris Water Maze Test; Neuroprotective Agents; Oxidative Stress; Phenols; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cardiotoxicity; Cell Line; Disease Models, Animal; Doxorubicin; Forkhead Box Protein O1; Glucosides; Heart Diseases; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Nerve Tissue Proteins; Oxidative Stress; Phenols; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA-Binding Proteins; Signal Transduction; Ventricular Function, Left

Topics: Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; CD4 Lymphocyte Count; Chemokine CCL20; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Electrocardiography; Glucosides; Inflammation Mediators; Interleukin-17; MAP Kinase Signaling System; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols; Rabbits; Rhodiola; RNA, Messenger; Signal Transduction

Topics: Adult; Animals; Cell Line, Tumor; Disease Models, Animal; Female; Glucosides; Healthy Volunteers; Humans; Hyperpigmentation; Interferon Regulatory Factor-1; Male; Melanins; Melanocytes; Mice; Molecular Docking Simulation; Monophenol Monooxygenase; Phenols; Procollagen-Proline Dioxygenase; Protein Disulfide-Isomerases; Skin; Skin Aging; Skin Cream; Skin Lightening Preparations; Skin Pigmentation; Transcriptional Activation; Ubiquitination; Ultraviolet Rays; Upstream Stimulatory Factors; Young Adult

Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Cell Line; Cytokines; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucosides; Hepatitis; HMGB1 Protein; Humans; Hypoglycemic Agents; Liver; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phenols; Receptor for Advanced Glycation End Products; Signal Transduction; Toll-Like Receptor 4

Topics: Acute Lung Injury; Animals; Coculture Techniques; Disease Models, Animal; Epithelial Cells; Exosomes; Glucosides; Inflammation; Macrophages, Alveolar; Male; MicroRNAs; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction

Topics: 3-Hydroxybutyric Acid; Animals; Anticholesteremic Agents; Atherosclerosis; Cholesterol; Diet, High-Fat; Disease Models, Animal; Fatty Acids; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Glucose; Glucosides; Glycogen; Hypercholesterolemia; Lipidomics; Lipogenesis; Liver; Male; Mice, Inbred C57BL; Mice, Knockout, ApoE; Phenols; Proton Magnetic Resonance Spectroscopy

Topics: Animals; Apoptosis; Diabetic Cardiomyopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Heme Oxygenase-1; Male; Mice; Myocytes, Cardiac; Phenols; Proto-Oncogene Proteins c-akt; Signal Transduction; Ventricular Remodeling

Topics: Animals; Autophagy; Disease Models, Animal; Erectile Dysfunction; Glucosides; Humans; Male; Penile Erection; Penis; Phenols; Rats; Rats, Sprague-Dawley

Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Glucosides; Hepatocytes; Humans; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Phenols; Primary Cell Culture; Signal Transduction

Topics: Animals; Atherosclerosis; Biomarkers; Cell Cycle; Cell Cycle Proteins; Cell Line; Cellular Senescence; Disease Models, Animal; Endothelial Cells; Gene Expression Regulation; Genes, p53; Glucosides; Humans; Phenols

Topics: Animals; Anti-Inflammatory Agents; Aorta; beta-Galactosidase; Cells, Cultured; Cellular Senescence; Collagen; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cytokines; Disease Models, Animal; Glucosides; Human Umbilical Vein Endothelial Cells; Humans; Hyperhomocysteinemia; Inflammation Mediators; Male; Mice, Inbred BALB C; Phenols; Sirtuin 3; Up-Regulation; Vascular Remodeling

Topics: Alzheimer Disease; Animals; Disease Models, Animal; Glucosides; Glutathione; Hippocampus; Male; Malondialdehyde; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Phenols; Superoxide Dismutase

Topics: Animals; Aorta; Apoptosis; Cell Survival; Diabetes Complications; Disease Models, Animal; Endothelial Cells; Glucosides; Glycation End Products, Advanced; Heme Oxygenase-1; Human Umbilical Vein Endothelial Cells; Humans; Male; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Phenols; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction

Topics: AMP-Activated Protein Kinases; Animals; Biomarkers; Blood Glucose; Curcumin; Diet, High-Fat; Disease Models, Animal; Drug Combinations; Glucosides; Insulin; Insulin Resistance; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Non-alcoholic Fatty Liver Disease; Phenols; Rats, Sprague-Dawley; Signal Transduction

Topics: Animals; Apoptosis; Autophagy; Cells, Cultured; Disease Models, Animal; Disease Progression; Gene Knockdown Techniques; Glucosides; Humans; Intervertebral Disc Degeneration; Male; Mitochondria; Mitophagy; Nucleus Pulposus; Phenols; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Transfection; Tumor Necrosis Factor-alpha; Ubiquitin-Protein Ligases; Up-Regulation

Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arthritis, Gouty; Cell Movement; Cell Polarity; Chondrocytes; Crystallization; Cyclooxygenase 2; Cytochrome P-450 CYP4A; Disease Models, Animal; Down-Regulation; Glucosides; Interleukin-1beta; Macrophages; Male; Mice; Models, Biological; Neutrophils; NF-kappa B; Phenols; Phenotype; Rabbits; Rats, Wistar; RAW 264.7 Cells; Signal Transduction; STAT1 Transcription Factor; Synovial Fluid; Tumor Necrosis Factor-alpha; Uric Acid

Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Computational Biology; Disease Models, Animal; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Profiling; Glucosides; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Mice; Phenols; Signal Transduction; Tumor Microenvironment; Xenograft Model Antitumor Assays

Topics: Anemia; Animals; Bone Marrow; Bone Marrow Transplantation; Cell Count; Cell Lineage; Cell Proliferation; Disease Models, Animal; Glucosides; Hematopoiesis; Hematopoietic Stem Cells; Immunosuppression Therapy; Male; Mice; Pancytopenia; Phenols; Survival Analysis

Topics: Animals; Astrocytes; Cytokines; Disease Models, Animal; Gene Expression Regulation; Glucosides; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenols; Rats; Signal Transduction; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

Topics: Animals; Diabetic Nephropathies; Disease Models, Animal; DNA, Mitochondrial; Electron Transport; Glucosides; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Mitochondria; Phenols; Podocytes; Sirtuin 1; Streptozocin; Transcription Factors; Up-Regulation

Topics: Adaptor Proteins, Signal Transducing; Alkaline Phosphatase; Animals; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Cell Survival; Collagen Type I; Collagen Type I, alpha 1 Chain; Disease Models, Animal; Female; Glucosides; Humans; Interleukin-6; Membrane Proteins; Mice; Osteoblasts; Osteocalcin; Osteoclasts; Osteoporosis; Phenols; Plant Extracts; RANK Ligand; Reactive Oxygen Species; Rhodiola; Transcription, Genetic

Topics: Animals; Benzylisoquinolines; Caspase 3; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drugs, Chinese Herbal; Flavonoids; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Male; Mice; Mice, Nude; Phenols; Random Allocation; RNA, Messenger; RNA, Neoplasm; Saponins; Steroids; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

Topics: Animals; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Down-Regulation; Female; Gene Expression; Glucosides; Lung; Mice, Inbred BALB C; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenols; Phytotherapy

Topics: Acute Lung Injury; Animals; Disease Models, Animal; Glucosides; Herbicides; Immunohistochemistry; Lung; Male; Paraquat; Phenols; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Transforming Growth Factor beta1

Topics: Animals; Apoptosis; Disease Models, Animal; Gene Expression; Glucosides; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lung; Male; Mice; Mitochondria; Myocytes, Smooth Muscle; Phenols; Pulmonary Artery; Receptor, Adenosine A2A; RNA, Messenger; Signal Transduction; Vascular Remodeling

Topics: Animals; Brain Ischemia; Brain Waves; Carotid Arteries; Carotid Stenosis; Cerebrovascular Circulation; Cognition Disorders; Dementia, Vascular; Disease Models, Animal; Glucosides; Hippocampus; Male; Maze Learning; Phenols; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rhodiola

Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Brain; Brain Ischemia; Caspase 3; Disease Models, Animal; Dose-Response Relationship, Drug; Early Growth Response Transcription Factors; Glucosides; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; PC12 Cells; Phenols; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stroke; Time Factors

Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Glucosides; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Inflammation Mediators; Insulin-Like Growth Factor I; Lipopolysaccharides; Male; Myocarditis; Myocardium; Phenols; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Sepsis; Signal Transduction

Topics: Alzheimer Disease; Animals; bcl-2-Associated X Protein; Carrier Proteins; Caspase 9; Cell Cycle Proteins; Cognition Disorders; Cytokines; Disease Models, Animal; Down-Regulation; Escape Reaction; Galactose; Glucosides; Hippocampus; Male; Maze Learning; Phenols; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Time Factors; Up-Regulation

Topics: Alzheimer Disease; Animals; Avoidance Learning; Brain; Cognition; Disease Models, Animal; Galactose; Glucosides; Inflammation; Male; Memory; NF-kappa B; Phenols; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1

Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety Disorders; Conditioning, Psychological; Depressive Disorder; Disease Models, Animal; Drug Evaluation, Preclinical; Exploratory Behavior; Fear; Female; Freezing Reaction, Cataleptic; Glucosides; Male; Maze Learning; Memory; Mice, Inbred C57BL; Motor Activity; Nootropic Agents; Phenols; Phytotherapy; Plant Extracts; Rhodiola

Topics: Alzheimer Disease; Animals; Disease Models, Animal; Drosophila; Glucosides; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phenols; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rhodiola; Signal Transduction

Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Biogenic Monoamines; Depression; Disease Models, Animal; Glucosides; Interleukin-1beta; Interleukin-6; Male; NF-kappa B; Olfactory Bulb; Phenols; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Rhodiola; Signal Transduction

Topics: Animals; Apoptosis; Carcinoma, Renal Cell; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Glucosides; Humans; Janus Kinase 2; Kidney Neoplasms; Male; Mice; Phenols; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

Topics: Animals; Calcification, Physiologic; Cell Cycle; Cell Differentiation; Cell Line; Cell Proliferation; Cell Survival; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Fracture Healing; Glucosides; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Osteoblasts; Osteogenesis; Phenols; Platelet Endothelial Cell Adhesion Molecule-1; Rats, Sprague-Dawley; Signal Transduction; Sp7 Transcription Factor; Transcription Factors; Transcriptional Activation; Vascular Endothelial Growth Factor A

Topics: Angiogenesis Inducing Agents; Animals; Cell Communication; Cell Line; Disease Models, Animal; Endothelial Cells; Glucosides; Hindlimb; Humans; Injections, Intramuscular; Ischemia; Mice, Inbred BALB C; Muscle Cells; Neovascularization, Physiologic; Phenols; Procollagen-Proline Dioxygenase

Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Caspase 3; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Glucosides; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Oxidative Stress; Phenols; Tumor Necrosis Factor-alpha

Topics: Analysis of Variance; Animals; Bulimia; Disease Models, Animal; Feeding Behavior; Female; Glucosides; Phenols; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhodiola; Stress, Psychological

Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cells, Cultured; Disease Models, Animal; Glucosides; Male; Membrane Potentials; Mitochondria, Heart; Myocardial Ischemia; Myocytes, Cardiac; Phenols; Phosphorylation; Phytotherapy; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rhodiola; Up-Regulation

Topics: Animals; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Brain Ischemia; Cell Survival; Cerebral Cortex; Disease Models, Animal; Drug Administration Schedule; Galactosides; Glucosides; Hydrogen Peroxide; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotective Agents; Oxidants; Phenols; Phenylethyl Alcohol; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury

Topics: Acute Lung Injury; Animals; Cytokines; Disease Models, Animal; Glucosides; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Phenols; Rhodiola

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Disease Models, Animal; Glucosides; Male; Maze Learning; NF-kappa B; Nitric Oxide; Phenols; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Superoxide Dismutase

Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Cerebral Cortex; Disease Models, Animal; Evans Blue; Gene Expression; Glucosides; Male; Phenols; Protective Agents; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha

Topics: Administration, Oral; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Depression; Disaccharides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Glucosides; Male; Molecular Structure; Phenols; Phenylethyl Alcohol; Piper nigrum; Plant Preparations; Plant Roots; Rats; Rats, Wistar; Rhodiola; Stress, Physiological