rhodanine and Hepatitis-C

rhodanine has been researched along with Hepatitis-C* in 1 studies

Other Studies

1 other study(ies) available for rhodanine and Hepatitis-C

Article	Year
Arylalkylidene rhodanine with bulky and hydrophobic functional group as selective HCV NS3 protease inhibitor. Bioorganic & medicinal chemistry letters, 2001, Jan-22, Volume: 11, Issue:2 Arylalkylidene rhodanines 2(a-d) inhibit HCV NS3 protease at moderate concentrations. They are better inhibitors of other serine proteases such as chymotrypsin and plasmin. However, the selectivity of arylmethyliden e rhodanines (8a, 9a) with bulkier and more hydrophobic functional groups increases by 13- and 25-fold towards HCV NS3 protease respectively. Topics: Antiviral Agents; Chymotrypsin; Combinatorial Chemistry Techniques; Fibrinolysin; Hepatitis C; Inhibitory Concentration 50; Rhodanine; Serine Proteinase Inhibitors; Structure-Activity Relationship; Viral Nonstructural Proteins	2001

Article

Year

Arylalkylidene rhodanine with bulky and hydrophobic functional group as selective HCV NS3 protease inhibitor.

Bioorganic & medicinal chemistry letters, 2001, Jan-22, Volume: 11, Issue:2

Arylalkylidene rhodanines 2(a-d) inhibit HCV NS3 protease at moderate concentrations. They are better inhibitors of other serine proteases such as chymotrypsin and plasmin. However, the selectivity of arylmethyliden e rhodanines (8a, 9a) with bulkier and more hydrophobic functional groups increases by 13- and 25-fold towards HCV NS3 protease respectively.

Topics: Antiviral Agents; Chymotrypsin; Combinatorial Chemistry Techniques; Fibrinolysin; Hepatitis C; Inhibitory Concentration 50; Rhodanine; Serine Proteinase Inhibitors; Structure-Activity Relationship; Viral Nonstructural Proteins

2001