rhizoxin and Kidney-Neoplasms

rhizoxin has been researched along with Kidney-Neoplasms* in 1 studies

Trials

1 trial(s) available for rhizoxin and Kidney-Neoplasms

Article	Year
Phase II trials of rhizoxin in advanced ovarian, colorectal and renal cancer. British journal of cancer, 1995, Volume: 72, Issue:5 Rhizoxin is a tubulin-binding anti-neoplastic agent which is active in a range of murine tumour models. The recommended schedule, of intravenous (i.v.) bolus administration at a dose of 2 mg m-2 every 3 weeks, has been assessed in three phase II trials of ovarian, renal and colorectal cancer. In general terms the drug was fairly well tolerated, but the response rate was disappointing: 0/18, colorectal cancer; 0/18, renal cancer; 1 partial response (PR)/17, ovarian cancer. Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Female; Humans; Kidney Neoplasms; Lactones; Macrolides; Middle Aged; Ovarian Neoplasms; Treatment Outcome	1995

Article

Year

Phase II trials of rhizoxin in advanced ovarian, colorectal and renal cancer.

British journal of cancer, 1995, Volume: 72, Issue:5

Rhizoxin is a tubulin-binding anti-neoplastic agent which is active in a range of murine tumour models. The recommended schedule, of intravenous (i.v.) bolus administration at a dose of 2 mg m-2 every 3 weeks, has been assessed in three phase II trials of ovarian, renal and colorectal cancer. In general terms the drug was fairly well tolerated, but the response rate was disappointing: 0/18, colorectal cancer; 0/18, renal cancer; 1 partial response (PR)/17, ovarian cancer.

Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Colorectal Neoplasms; Female; Humans; Kidney Neoplasms; Lactones; Macrolides; Middle Aged; Ovarian Neoplasms; Treatment Outcome

1995