Page last updated: 2024-08-21

rhein and Kidney Diseases

rhein has been researched along with Kidney Diseases in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (44.44)24.3611
2020's5 (55.56)2.80

Authors

AuthorsStudies
Du, Z; Song, X; Tang, X; Yao, Z; Zhang, M1
Cheng, Y; Jiang, J; Lin, H; Liu, S; Wang, Y; Xiang, Z; Xiao, Q; Ye, X; Yu, X; Zhang, X1
Hu, J; Wang, D; Wu, H; Yang, Z1
Feng, F; Li, G; Shen, Y; Sun, H; Xiang, Z1
Hu, H; Jiang, H; Ma, L; Shen, Z; Yu, L; Zeng, S; Zhou, H1
Hu, G; Lin, YJ; Liu, J; Qiao, Y; Tu, P; Wei, J; Xu, R; Zhen, YZ1
Ding, G; Guo, C; Huang, W; Li, N; Meng, Z; Tang, Z; Wang, Z; Xiao, W; Yan, Y; Yang, Z1
Cai, X; Chen, D; Luo, G; Sun, H; Xiang, Z1
Li, RS; Shan, LM; Wang, JB; Xiao, XH; Yang, HB; Zhao, YL; Zhou, GD1

Other Studies

9 other study(ies) available for rhein and Kidney Diseases

ArticleYear
Rhein Improves Renal Fibrosis by Restoring Cpt1a-Mediated Fatty Acid Oxidation through SirT1/STAT3/twist1 Pathway.
    Molecules (Basel, Switzerland), 2022, Apr-06, Volume: 27, Issue:7

    Topics: Animals; Anthraquinones; Carnitine O-Palmitoyltransferase; Epithelial-Mesenchymal Transition; Fatty Acids; Fibrosis; Kidney Diseases; Rats; Sirtuin 1; STAT3 Transcription Factor; Twist-Related Protein 1

2022
An integrated network pharmacology and cell metabolomics approach to reveal the role of rhein, a novel PPARĪ± agonist, against renal fibrosis by activating the PPARĪ±-CPT1A axis.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Jul-20, Volume: 102

    Topics: Animals; Anthraquinones; Fibrosis; Kidney Diseases; Metabolomics; Network Pharmacology; PPAR alpha; Rats; Rats, Sprague-Dawley

2022
Rhein attenuates renal inflammatory injury of uric acid nephropathy via lincRNA-Cox2/miR-150-5p/STAT1 axis.
    International immunopharmacology, 2020, Volume: 85

    Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Apoptosis; Cell Line; Cell Proliferation; Cyclooxygenase 2; Inflammation; Interleukin-1beta; Interleukin-6; Kidney Diseases; Mice; MicroRNAs; RNA, Long Noncoding; STAT1 Transcription Factor; Tumor Necrosis Factor-alpha; Uric Acid

2020
Quantitative and network pharmacology: A case study of rhein alleviating pathological progress of renal interstitial fibrosis.
    Journal of ethnopharmacology, 2020, Oct-28, Volume: 261

    Topics: Animals; Anthraquinones; Cell Line; Computer Simulation; Disease Models, Animal; Fibrosis; Focal Adhesion Kinase 1; Humans; Kidney; Kidney Diseases; Models, Biological; Rats; Signal Transduction; Smad3 Protein; Systems Biology

2020
Effects of rhein and Rheum palmatum L. extract on the pharmacokinetics and tissue distribution of aristolochic acid I and its demethylated metabolite in rats.
    Journal of ethnopharmacology, 2021, Mar-01, Volume: 267

    Topics: Animals; Anthraquinones; Aristolochic Acids; Biotransformation; Demethylation; Injections, Intravenous; Kidney; Kidney Diseases; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Plant Extracts; Rats, Sprague-Dawley; Rheum; Tissue Distribution

2021
Rhein lysinate increases the median survival time of SAMP10 mice: protective role in the kidney.
    Acta pharmacologica Sinica, 2013, Volume: 34, Issue:4

    Topics: Adenine Nucleotides; Animals; Anthraquinones; Body Weight; Collagen Type I; Collagen Type III; Glomerulonephritis; Glutathione; Interleukin-6; Kidney Diseases; Macrophages; Male; Mice; Mycophenolic Acid; NF-kappa B; Rhizome; Superoxide Dismutase; Survival Rate; Tumor Necrosis Factor-alpha

2013
Anti-hyperuricemic and nephroprotective effects of rhein in hyperuricemic mice.
    Planta medica, 2015, Volume: 81, Issue:4

    Topics: Animals; Anthraquinones; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Drugs, Chinese Herbal; Hyperuricemia; Interleukin-1beta; Kidney; Kidney Diseases; Male; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters; Phytotherapy; Protective Agents; Rheum; Tumor Necrosis Factor-alpha; Uric Acid

2015
Pharmacokinetics and pharmacodynamics study of rhein treating renal fibrosis based on metabonomics approach.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2016, Dec-01, Volume: 23, Issue:13

    Topics: Animals; Anthraquinones; Biomarkers; Chromatography, Liquid; Fibrosis; Kidney Diseases; Male; Metabolomics; Rats, Sprague-Dawley; Rheum; Tandem Mass Spectrometry

2016
Rhein protects against acetaminophen-induced hepatic and renal toxicity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:8

    Topics: Acetaminophen; Alanine Transaminase; Animals; Anthraquinones; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Creatinine; Glutathione; Kidney; Kidney Diseases; Liver; Male; Nitric Oxide; Nitrogen; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2011