rhein has been researched along with Diabetic Nephropathies in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YX; Luo, J; Wang, PC; Wei, W; Yan, YM; Yang, Y; Yang, YX; Zhang, LS; Zhou, XJ | 1 |
| Chen, D; Han, S; Wang, G; Wang, Q; Zhu, Y | 1 |
| Fu, RJ; Mao, X; Tang, YP; Xu, DQ; Yue, SJ; Zhang, S | 1 |
| Cai, Y; Han, X; Hu, W; Xiong, D | 1 |
| Chen, D; Huang, P; Li, Q; Tong, W; Wang, G; Wu, B; Wu, Y | 1 |
| Chen, J; Jiang, Y; Lei, G; Liu, M; Liu, S; Pei, R | 1 |
| Chen, D; Han, S; Hu, F; Wang, G; Wei, Y; Zhu, Y | 1 |
| Chen, M; Duan, S; Wu, Y; Xing, C; Yuan, Y; Zhang, B; Zhao, C | 1 |
| Gao, Q; Jia, ZH; Li, LS; Liu, ZH; Qin, WS; Zeng, CH; Zheng, JM | 1 |
| Gao, Y; Liu, XH; Yu, DQ | 1 |
| Gu, L; Wan, M; Wan, Y | 1 |
| Jia, ZH; Li, LS; Liu, ZH; Zeng, CH; Zheng, JM | 1 |
| Li, LS; Liu, ZH; Zheng, JM; Zhu, JM | 1 |
| Li, Y; Liu, Z; Zhang, J | 1 |
3 review(s) available for rhein and Diabetic Nephropathies
| Article | Year |
|---|---|
Potential Medicinal Value of Rhein for Diabetic Kidney Disease.
Topics: Anthraquinones; Diabetes Mellitus; Diabetic Nephropathies; Humans; Kidney | 2023 |
Rhein Derivatives, A Promising Pivot?
Topics: Animals; Anthraquinones; Arthritis; Cell Line, Tumor; Chemistry, Pharmaceutical; Diabetic Nephropathies; Drug Design; Humans; Inflammation; Inhibitory Concentration 50; Neoplasms | 2021 |
[Advances in the study on molecular mechanism of diabetic nephropathy treated with Rheum officinale].
Topics: Animals; Anthraquinones; Cytokines; Diabetic Nephropathies; Drugs, Chinese Herbal; Emodin; Humans; Interleukin-6; Plants, Medicinal; Rheum; Superoxide Dismutase; Thromboxane B2; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2003 |
11 other study(ies) available for rhein and Diabetic Nephropathies
| Article | Year |
|---|---|
Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy.
Topics: Anthraquinones; Aspergillus fumigatus; Cell Survival; Diabetic Nephropathies; Dose-Response Relationship, Drug; Extracellular Matrix; Glycosides; Humans; Interleukin-6; Mesangial Cells; Molecular Structure; Naphthalenes; Renal Insufficiency, Chronic; Rumex; Structure-Activity Relationship | 2013 |
Poly-γ-glutamic acid coating polymeric nanoparticles enhance renal drug distribution and cellular uptake for diabetic nephropathy therapy.
Topics: Animals; Diabetes Mellitus; Diabetic Nephropathies; Glutamic Acid; Kidney; Mice; Nanoparticles; Polyethyleneimine; Polyglutamic Acid | 2023 |
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
Topics: Animals; beta Catenin; Diabetes Mellitus; Diabetic Nephropathies; Epithelial-Mesenchymal Transition; Ferroptosis; Mice; NADPH Oxidase 1; Reactive Oxygen Species | 2023 |
Kidney-targeted rhein-loaded liponanoparticles for diabetic nephropathy therapy via size control and enhancement of renal cellular uptake.
Topics: Animals; Anthraquinones; Biological Transport; Cell Line; Creatinine; Diabetic Nephropathies; Drug Delivery Systems; Fibronectins; Humans; Kidney; Mice; Mice, Inbred C57BL; Nanoparticles; Polyesters; Polyethyleneimine; Streptozocin; Transforming Growth Factor beta1 | 2019 |
Kidney-targeted drug delivery via rhein-loaded polyethyleneglycol-
Topics: Animals; Anthraquinones; Blood Glucose; Cell Death; Chromatography, Gel; Diabetic Nephropathies; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Endocytosis; Fasting; Hemolysis; Humans; Kidney; Kinetics; Male; Mice, Inbred C57BL; Nanoparticles; Particle Size; Polyethylene Glycols; Polyethyleneimine; Rabbits; Static Electricity; Streptozocin; Subcellular Fractions | 2018 |
The wnt/β-catenin signaling pathway participates in rhein ameliorating kidney injury in DN mice.
Topics: Animals; Anthraquinones; beta Catenin; Blood Glucose; Diabetic Nephropathies; Male; Membrane Proteins; Mice; Signal Transduction; Wnt Proteins | 2016 |
Rhein improves renal lesion and ameliorates dyslipidemia in db/db mice with diabetic nephropathy.
Topics: Albuminuria; Animals; Anthraquinones; Anticholesteremic Agents; Cholesterol; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drugs, Chinese Herbal; Dyslipidemias; Extracellular Matrix; Fibronectins; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Phytotherapy; Rheum; Rhizome; Simvastatin; Transforming Growth Factor beta1 | 2010 |
[Effects of Rhein on the hypertrophy of renal proximal tubular epithelial cells induced by high glucose and angiotensin II in rats].
Topics: Angiotensin II; Animals; Anthraquinones; Cells, Cultured; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Epithelial Cells; Glucose; Hypertrophy; Kidney Tubules, Proximal; Leucine; Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Rheum | 2010 |
Combined therapy of rhein and benazepril on the treatment of diabetic nephropathy in db/db mice.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Anthraquinones; Benzazepines; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Enzyme Inhibitors; Fibronectins; Fluorescent Antibody Technique, Direct; Immunohistochemistry; Mice; Mice, Inbred C57BL; Random Allocation; Transforming Growth Factor beta; Triglycerides | 2007 |
Rhein reverses the diabetic phenotype of mesangial cells over-expressing the glucose transporter (GLUT1) by inhibiting the hexosamine pathway.
Topics: Animals; Anthraquinones; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Diabetic Nephropathies; Enzyme Inhibitors; Extracellular Matrix; Gene Expression Regulation; Glucose Transporter Type 1; Hexosamines; Hypertrophy; Male; Mesangial Cells; Phenotype; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2008 |
[Modulatory effect of transforming growth factor-beta and Rhein on glucose transporter-1 in human glomerular mesangial cells].
Topics: Anthraquinones; Cells, Cultured; Diabetic Nephropathies; Glomerular Mesangium; Humans; Monosaccharide Transport Proteins; RNA, Messenger; Transforming Growth Factor beta | 1999 |