rhein has been researched along with Cell Transformation, Neoplastic in 4 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 2 (50.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Chae, JI; Cho, JH; Shim, JH | 1 |
Fujii, M; Hou, DX; Li, JJ; Lin, S | 1 |
de Jong, S; de Vries, EG; Kleibeuker, JH; Timmer-Bosscha, H; van der Kolk, DM; van Gorkom, BA | 1 |
Marquardt, H; Schmutte, C; Westendorf, J; Wölfle, D | 1 |
4 other study(ies) available for rhein and Cell Transformation, Neoplastic
Article | Year |
---|---|
Rhein exhibits antitumorigenic effects by interfering with the interaction between prolyl isomerase Pin1 and c-Jun.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Embryo, Mammalian; Enzyme Inhibitors; Fibroblasts; Flow Cytometry; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Knockout; NIMA-Interacting Peptidylprolyl Isomerase; Polymerase Chain Reaction; Signal Transduction | 2017 |
Rhein inhibits TPA-induced activator protein-1 activation and cell transformation by blocking the JNK-dependent pathway.
Topics: Animals; Anthraquinones; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Luciferases; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Chemical; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation | 2003 |
Cytotoxicity of rhein, the active metabolite of sennoside laxatives, is reduced by multidrug resistance-associated protein 1.
Topics: Anthraquinones; Apoptosis; Cell Transformation, Neoplastic; Colonic Neoplasms; Enzyme Inhibitors; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Multidrug Resistance-Associated Proteins; Tumor Cells, Cultured | 2002 |
Hydroxyanthraquinones as tumor promoters: enhancement of malignant transformation of C3H mouse fibroblasts and growth stimulation of primary rat hepatocytes.
Topics: Animals; Anthraquinones; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Liver; Male; Methylcholanthrene; Methylnitronitrosoguanidine; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1990 |