rhein has been researched along with Alzheimer Disease in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Andrisano, V; Bartolini, M; Clos, MV; De Simone, A; Inestrosa, NC; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sabaté, R; Serrano, FG; Sola, I; Tapia-Rojas, C; Viayna, E | 1 |
| Gao, D; Gao, X; Lu, L; Luo, G; Ma, T; Wang, Y; Yin, Z; Zhang, Z | 1 |
| Jemiola-Rzeminska, M; Muñoz-Torrero, D; Strzalka, K; Suwalsky, M; Zambrano, P | 1 |
| Andrisano, V; Bartolini, M; Betari, N; De Simone, A; Espargaró, A; Lamuela-Raventós, RM; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Pérez-Areales, FJ; Pont, C; Rinaldi Alvarenga, JF; Sabate, R; Viayna, A | 1 |
| Ding, X; Duan, P; Hu, G; Lin, YJ; Liu, J; Qiao, Y; Tu, P; Wu, HP; Xu, R | 1 |
| Jiang, N; Kong, LY; Li, SY; Wang, KD; Wang, XB; Xie, SS | 1 |
6 other study(ies) available for rhein and Alzheimer Disease
| Article | Year |
|---|---|
Synthesis and multitarget biological profiling of a novel family of rhein derivatives as disease-modifying anti-Alzheimer agents.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Anthraquinones; Aspartic Acid Endopeptidases; Binding Sites; Blood-Brain Barrier; Cholinesterase Inhibitors; Enzyme Inhibitors; Escherichia coli; Hippocampus; Humans; In Vitro Techniques; Kinetics; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Molecular; Peptide Fragments; Stereoisomerism; Synapses; tau Proteins | 2014 |
Stepwise Coordination-Driven Metal-Phenolic Nanoparticle as a Neuroprotection Enhancer for Alzheimer's Disease Therapy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Mice; Mice, Transgenic; Molecular Docking Simulation; Nanoparticles; Neuroprotection | 2023 |
A rhein-huprine hybrid protects erythrocyte membrane integrity against Alzheimer's disease related Aβ(1-42) peptide.
Topics: Alzheimer Disease; Dimyristoylphosphatidylcholine; Erythrocyte Membrane; Erythrocytes; Humans; Lipid Bilayers; Microscopy, Electron, Scanning; Peptides; Phosphatidylethanolamines; X-Ray Diffraction | 2023 |
Design, synthesis and multitarget biological profiling of second-generation anti-Alzheimer rhein-huprine hybrids.
Topics: Acetylcholinesterase; Alzheimer Disease; Aminoquinolines; Anthraquinones; Antioxidants; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Heterocyclic Compounds, 4 or More Rings; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship | 2017 |
Rhein lysinate decreases the generation of β-amyloid in the brain tissues of Alzheimer's disease model mice by inhibiting inflammatory response and oxidative stress.
Topics: Aging; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Anthraquinones; Brain; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glutathione Peroxidase; Interleukin-6; Lysine; Male; Malondialdehyde; Mice; Oxidative Stress; Sirtuin 1; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2013 |
Design, synthesis and evaluation of novel tacrine-rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anthraquinones; Chemistry Techniques, Synthetic; Cholinesterase Inhibitors; Drug Design; Kinetics; Liver; Metals; Mice; Molecular Docking Simulation; Peptide Fragments; Protein Multimerization; Protein Structure, Secondary; Tacrine | 2014 |