rhein has been researched along with Acute Liver Injury, Drug-Induced in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, J; Liu, S; Wei, F; Yang, Z; Yin, R | 1 |
| Liu, Y; Ma, SC; Wang, Q; Wang, YD; Wen, HR; Yang, JB | 1 |
| Chen, SY; Gao, Y; Huang, WY; Li, YQ; Meng, XL; Su, SY; Wang, P; Yang, D | 1 |
| Chen, JX; Cui, TY; Fan, YW; He, LN; He, X; Jin, CH; Wang, LL; Wu, ZJ; Yang, AH; Zhai, YR; Zhang, FL | 1 |
| Li, RS; Shan, LM; Wang, JB; Xiao, XH; Yang, HB; Zhao, YL; Zhou, GD | 1 |
| Jiao, G; Sun, H; Sun, W; Wang, X; Yuan, Y; Zhang, A | 1 |
| Fang, F; Jin, C; Kong, WJ; Wang, HJ; Wang, JB; Xiao, XH; Zhao, HP; Zhao, YL | 1 |
7 other study(ies) available for rhein and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
The effects of rhein on D-GalN/LPS-induced acute liver injury in mice: Results from gut microbiome-metabolomics and host transcriptome analysis.
Topics: Animals; Chemical and Drug Induced Liver Injury; Galactosamine; Gastrointestinal Microbiome; Gene Expression Profiling; Lipopolysaccharides; Mice; RNA, Ribosomal, 16S | 2022 |
[Study on potential hepatotoxicity of rhein in Rhei Radix et Rhizoma based on liver metabolism].
Topics: Anthraquinones; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Glucuronosyltransferase; Humans; Liver; Microsomes, Liver; Rhizome | 2020 |
Acute and subchronic toxicity studies of rhein in immature and d-galactose-induced aged mice and its potential hepatotoxicity mechanisms.
Topics: Aged; Animals; Anthraquinones; Chemical and Drug Induced Liver Injury; Galactose; Humans; Liver; Mice; Oxidative Stress | 2022 |
Reactive metabolite activation by CYP2C19-mediated rhein hepatotoxicity.
Topics: Animals; Anthraquinones; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Drug Interactions; Glutathione; Hepatocytes; Inhibitory Concentration 50; Male; Membrane Potential, Mitochondrial; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tandem Mass Spectrometry | 2015 |
Rhein protects against acetaminophen-induced hepatic and renal toxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Anthraquinones; Antioxidants; Bilirubin; Chemical and Drug Induced Liver Injury; Creatinine; Glutathione; Kidney; Kidney Diseases; Liver; Male; Nitric Oxide; Nitrogen; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2011 |
An in vivo analysis of the therapeutic and synergistic properties of Chinese medicinal formula Yin-Chen-Hao-Tang based on its active constituents.
Topics: Animals; Anthraquinones; Artemisia; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Drug Combinations; Drug Synergism; Drugs, Chinese Herbal; Gardenia; Iridoids; Least-Squares Analysis; Magnoliopsida; Male; Phytotherapy; Principal Component Analysis; Rats; Rats, Wistar; Rheum; Umbelliferones | 2011 |
A comparative study on the tissue distributions of rhubarb anthraquinones in normal and CCl4-injured rats orally administered rhubarb extract.
Topics: Administration, Oral; Animals; Anthraquinones; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Liquid; Disease Models, Animal; Drugs, Chinese Herbal; Emodin; Female; Kidney; Liver; Male; Plant Roots; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Rheum; Spleen; Tandem Mass Spectrometry; Tissue Distribution | 2011 |