rhamnogalacturonan-i has been researched along with Neoplasm-Metastasis* in 1 studies
1 other study(ies) available for rhamnogalacturonan-i and Neoplasm-Metastasis
| Article | Year |
|---|---|
Rhamnogalacturonan-I-Type Polysaccharide Purified from Broccoli Exerts Anti-Metastatic Activities Via Innate Immune Cell Activation.
To examine the anti-metastatic activities of polysaccharides in broccoli, purified polysaccharides (BCE-I, -II, and -III) were isolated by fractionation of broccoli enzyme extracts and subsequent ethanol precipitation. BCE-I mainly consisted of galactose and arabinose, whereas BCE-II mainly consisted of galacturonic acid and rhamnose, and BCE-III mainly consisted of rhamnose and galactose. Of the three fractions, stimulation of murine peritoneal macrophages by BCE-I showed the greatest enhancement of tumor necrosis factor-α, interleukin (IL)-12, and IL-6 secretion. In addition, intravenous (i.v.) administration of BCE-I enhanced the lethal activity of natural killer (NK) cells on YAC-1 tumor cells significantly and dose-dependently in an Topics: Animals; Antineoplastic Agents, Phytogenic; Brassica; Colonic Neoplasms; Female; Humans; Immunity, Innate; Interleukin-12; Interleukin-6; Killer Cells, Natural; Lung Neoplasms; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Pectins; Plant Extracts; Polysaccharides | 2019 |