rg108 and Leukemia

rg108 has been researched along with Leukemia* in 1 studies

Other Studies

1 other study(ies) available for rg108 and Leukemia

Article	Year
Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia cell line. Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6 The known DNMT inhibitor SGI-1027 4 has been synthesized using as key steps Pd-catalyzed Ar-N bond formation reactions performed in a sequential or convergent manner. In the former approach, a by-product, which corresponds to the incorporation of two units of 4-chloroquinoline, was also isolated. The biological effects of compound 4 in the U937 human leukemia cell line are also described. Topics: Aminoquinolines; Catalysis; Cell Cycle Checkpoints; DNA (Cytosine-5-)-Methyltransferases; Enzyme Inhibitors; Humans; Leukemia; Palladium; Pyrimidines; U937 Cells	2013

Article

Year

Synthetic approaches to DNMT inhibitor SGI-1027 and effects on the U937 leukemia cell line.

Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

The known DNMT inhibitor SGI-1027 4 has been synthesized using as key steps Pd-catalyzed Ar-N bond formation reactions performed in a sequential or convergent manner. In the former approach, a by-product, which corresponds to the incorporation of two units of 4-chloroquinoline, was also isolated. The biological effects of compound 4 in the U937 human leukemia cell line are also described.

Topics: Aminoquinolines; Catalysis; Cell Cycle Checkpoints; DNA (Cytosine-5-)-Methyltransferases; Enzyme Inhibitors; Humans; Leukemia; Palladium; Pyrimidines; U937 Cells

2013