retinylidene-dimedone and Neoplasms

retinylidene-dimedone has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for retinylidene-dimedone and Neoplasms

ArticleYear
Potential prophylactic antitumor activity of retinylidene 1,3-diketones.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:7

    Treatment of all-trans-retinal with a series of 1,3-diketones using Knoevenagel conditions gave the expected condensation products. These retinylidene 1,3-diketones were characterized and their biological activities in the hamster tracheal organ culture test measured. It was found that the cyclohexane- 1,3-dione derivatives are highly active in this in vitro assay, while other 1,3-diketones are less active. Retinylidenedimedone has been chosen for further evaluation.

    Topics: Animals; Cell Differentiation; Cricetinae; Epithelial Cells; Epithelium; Ketones; Neoplasms; Organ Culture Techniques; Retinaldehyde; Trachea; Vitamin A

1980