retinol and Retinal Degeneration

retinol has been researched along with Retinal Degeneration in 75 studies

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-199031 (41.33)18.7374
1990's6 (8.00)18.2507
2000's14 (18.67)29.6817
2010's14 (18.67)24.3611
2020's10 (13.33)2.80

Authors

AuthorsStudies
Mihai, DM; Washington, I; Zhang, D1
Robinson, K; Washington, I; Zhang, D1
Chang, YJ; Cheng, CH; Cui, X; Hsu, CW; Huang, IW; Jenny, LA; Kim, HJ; Kong, Y; Li, X; Lima de Carvalho, JR; Lin, CS; Ragi, SD; Sparrow, JR; Tsang, SH1
Komorowski, M; Krześniak, N; Lutyńska, A; Malejczyk, J; Radziszewski, M; Ścieżyńska, A; Shevchenko, K; Soszyńska, M; Łuszczyński, K1
Bisti, S; Maggi, MA; Picco, C1
Chang, MY; Ellis, MP; Yiu, G1
Al-Asmari, AM; Al-Kahtani, MA; El-Bealy, EA; El-Mansi, AA; Rady, AM1
Inoue, E; Ishida, N; Kawasaki, H; Shimizu, Y; Sudo, K; Suzuki, T1
Ha, T; Kim, JW; Kim, S; Kim, YJ; Lim, S; Park, S; You, H1
Robinson, K; Saad, L; Washington, I; Zhang, D1
Cioffi, CL; Ma, JX; Moiseyev, G; Muthuraman, P; Petrukhin, K; Shin, Y; Takahashi, Y1
Banerjee, S; Blaner, WS; Chelstowska, S; Golczak, M; Horwitz, S; Kiser, PD; Silvaroli, JA; Trischman, T; Widjaja-Adhi, MAK1
Mihai, DM; Washington, I1
Corbo, JC; Cornwall, MC; Estevez, ME; Frederiksen, R; Kefalov, VJ; Nymark, S; Shen, SQ; Wang, JS1
Kaushal, S; Kono, M; Moritz, OL; Noorwez, SM; Tam, BM1
Mihai, DM; Penn, J; Washington, I1
Saad, L; Washington, I1
Jin, M; Lee, M; Li, S; Sato, K1
Bok, D; Hu, J; Lloyd, M; Nusinowitz, S; Peng, JH; Radu, RA; Travis, GH; Yuan, Q1
Maeda, A; Maeda, T; Ohguro, H1
Chou, S; Desai, A; Golczak, M; Hoppel, CL; Maeda, A; Maeda, T; Matsuyama, S; Palczewski, K1
Casadesus, G; Maeda, A; Maeda, T; Margaron, P; Palczewski, K1
Lee, HC; Moritz, OL; Qazalbash, A; Tam, BM1
Hara, H; Imai, S; Nakanishi, T; Shimazawa, M; Tsuruma, K; Umigai, N; Yamauchi, M1
Kaufman, Y; Ma, L; Washington, I; Zhang, J1
Chen, Y; Hu, Y; Ma, JX; Moiseyev, G; Mott, R; Takahashi, Y1
Ananthathmakula, P; Ayyagari, R; Ayyalasomayajula, V; Nappanveettil, G; Reddy, GB; Tiruvalluru, M1
Chen, Y; Kohno, H; Le, YZ; Maeda, A; Maeda, T; Sawada, O; Subauste, C1
KANZAWA, T; MIMA, H1
CHATZINOFF, A; MILLMAN, N; OROSHNIK, W; ROSEN, F1
DANIELS, H; GIJZEN, AH; INDEMANS, AW1
Beard, J; Chen, L; Dentchev, T; Dunaief, JL; Hahn, P; Harris, ZL; Qian, Y1
Bok, D; Bui, TV; Han, Y; Lichter, J; Mata, NL; Nusinowitz, S; Radu, RA; Travis, GH; Widder, K1
Chen, Y; Ma, JX; Moiseyev, G; Takahashi, Y1
Montell, C; Wang, T1
Alvarez, RA; Bridges, CD1
Fried, D; Goodman, RM; Hanukoglu, A; Romem, M; Yaniv, I1
Daemen, FJ; Jansen, PA1
Hayes, KC1
Armstrong, D; Gutteridge, J; Hiramitsu, T; Nilsson, SE1
Azizi, E; Bishara, S; Cooper, M; Deckelbaum, RJ; Delpre, G; Merin, S1
Berson, EL1
Cideciyan, AV; Jacobson, SG; Regunath, G; Rodriguez, FJ; Sheffield, VC; Stone, EM; Vandenburgh, K1
Milam, AH1
Gao, CL; Katz, ML; Norberg, M; Stientjes, HJ1
Crane, WG1
Héon, E; Wong, AM1
Ehinger, B1
Ali, RR; Bessant, DA; Bhattacharya, SS1
Cideciyan, AV; Jacobson, SG; Wright, AF; Wright, E1
Biesalski, HK; Seeliger, M1
Rüther, K; Zrenner, E1
Banin, E; Chowers, I; Cooper, M; Granot, E; Merin, S1
Rodger, FC1
Young, RW2
Cohen, J1
Bergsma, DR; Chader, GJ; Helmsen, R; Wiggert, B1
Schmidt, JG1
Carr, RE1
Bergsma, DR; Wolf, ML1
Bird, AC; Lloyd, JK; Muller, DP1
Barron, G; Dewar, AJ1
Dewar, AJ; Reading, HW1
Barron, G; Dewar, AJ; Reading, HW1
Delmelle, M; Noell, WK; Organisciak, DT1
Doden, W1
Cacioppa, F; Livrea, MA; Nicotra, C1
Bridges, CD; Fong, SL; Gonzalez-Fernandez, F; Landers, RA; Liou, GI1
Alvarez, RA; Bridges, CD; Carter-Dawson, L; Sperling, HG1
Reading, HW1
Hruby, K1
Berson, EL; Hayes, KC; Rabin, AR1
Dieckhues, B1
Knappen, F; Seitz, R; Stötzer, H; Weisse, I1

Reviews

13 review(s) available for retinol and Retinal Degeneration

ArticleYear
[Retinal degeneration diseases and the retinoid cycle].
    Nippon Ganka Gakkai zasshi, 2009, Volume: 113, Issue:2

    Topics: Animals; Humans; Mice; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Retinal Pigment Epithelium; Vitamin A

2009
Phototransduction and retinal degeneration in Drosophila.
    Pflugers Archiv : European journal of physiology, 2007, Volume: 454, Issue:5

    Topics: Adaptation, Ocular; Animals; Calcium Channels; Drosophila; Drosophila Proteins; Eye Proteins; Genes, Insect; GTP-Binding Proteins; Light; Multiprotein Complexes; Phosphatidylinositol 4,5-Diphosphate; Photoreceptor Cells, Invertebrate; Retinal Degeneration; Rhodopsin; Transient Receptor Potential Channels; Vision, Ocular; Vitamin A

2007
Selective loss of 11-cis vitamin A in an eye with hereditary chorioretinal degeneration similar to sector retinitis pigmentosa.
    Retina (Philadelphia, Pa.), 1982, Volume: 2, Issue:4

    Topics: Aged; Aged, 80 and over; Choroid Diseases; Female; Humans; Isomerism; Pigment Epithelium of Eye; Retinal Degeneration; Retinitis Pigmentosa; Vitamin A

1982
Nutritional problems in cats: taurine deficiency and vitamin A excess.
    The Canadian veterinary journal = La revue veterinaire canadienne, 1982, Volume: 23, Issue:1

    Topics: Animal Nutritional Physiological Phenomena; Animals; Cat Diseases; Cats; Cercopithecidae; Dogs; Female; Guinea Pigs; Humans; Male; Nutritional Requirements; Rabbits; Rats; Retinal Degeneration; Taurine; Vitamin A

1982
Strategies for rescue of retinal photoreceptor cells.
    Current opinion in neurobiology, 1993, Volume: 3, Issue:5

    Topics: Animals; Cell Transplantation; Genetic Therapy; Humans; Light; Photoreceptor Cells; Pigment Epithelium of Eye; Retinal Degeneration; Vitamin A

1993
Tapetoretinal degenerations: experiences, experiments and expectations.
    Acta ophthalmologica Scandinavica, 2000, Volume: 78, Issue:3

    Topics: Amino Acid Sequence; Animals; Electrooculography; Electroretinography; Genetic Therapy; Humans; Molecular Sequence Data; Mutation; Photoreceptor Cells, Vertebrate; Pigment Epithelium of Eye; Retina; Retinal Degeneration; Rhodopsin; Vitamin A

2000
Molecular genetics and prospects for therapy of the inherited retinal dystrophies.
    Current opinion in genetics & development, 2001, Volume: 11, Issue:3

    Topics: Carrier Proteins; cis-trans-Isomerases; Eye Proteins; Genetic Diseases, Inborn; Humans; Photoreceptor Cells; Proteins; Retina; Retinal Degeneration; Transcription Factors; Vision, Ocular; Vitamin A

2001
[Vitamin A metabolism and retinal degeneration].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2001, Volume: 98, Issue:6

    Topics: Humans; Photoreceptor Cells; Pigment Epithelium of Eye; Retinal Degeneration; Vitamin A; Vitamin A Deficiency

2001
[Administration of vitamin A derivatives in hereditary retinal degeneration. Status of recommendations].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2001, Volume: 98, Issue:6

    Topics: Animals; Diterpenes; Humans; Mice; Randomized Controlled Trials as Topic; Retinal Degeneration; Retinitis Pigmentosa; Retinyl Esters; Vitamin A

2001
Visual cell renewal systems and the problem of retinitis pigmentosa.
    Advances in experimental medicine and biology, 1977, Volume: 77

    Topics: Age Factors; Animals; Carrier Proteins; Cell Survival; DNA; Genes; Glycoproteins; Humans; Membranes; Nerve Tissue Proteins; Phospholipids; Photoreceptor Cells; Retinal Degeneration; Retinitis Pigmentosa; Taurine; Vitamin A

1977
Diseases of the retina: 1975-76 review.
    American journal of optometry and physiological optics, 1977, Volume: 54, Issue:7

    Topics: Adult; Anemia, Sickle Cell; Binding Sites; Cataract Extraction; Diabetic Retinopathy; Eye Neoplasms; Female; Fluorescein Angiography; Histoplasmosis; Humans; Infant; Infections; Macula Lutea; Male; Middle Aged; Retina; Retinal Degeneration; Retinal Detachment; Retinal Diseases; Retinal Vessels; Retinitis Pigmentosa; Retinoblastoma; Retinopathy of Prematurity; Toxoplasmosis, Ocular; Vitamin A

1977
Abetalipoproteinemia and the eye.
    Birth defects original article series, 1976, Volume: 12, Issue:3

    Topics: Abetalipoproteinemia; Adolescent; Child; Child, Preschool; Dark Adaptation; Electroretinography; Humans; Infant; Lipoproteins; Male; Retinal Degeneration; Vitamin A; Vitamin A Deficiency

1976
Renewal systems in rods and cones.
    Annals of ophthalmology, 1973, Volume: 5, Issue:8

    Topics: Animals; Autoradiography; Carbohydrates; Epithelium; Eye Proteins; Humans; Light; Microscopy, Electron; Phospholipids; Photoreceptor Cells; Retinal Degeneration; Retinal Detachment; RNA; Tritium; Vitamin A

1973

Trials

1 trial(s) available for retinol and Retinal Degeneration

ArticleYear
Long-term assessment of combined vitamin A and E treatment for the prevention of retinal degeneration in abetalipoproteinaemia and hypobetalipoproteinaemia patients.
    Eye (London, England), 2001, Volume: 15, Issue:Pt 4

    Topics: Abetalipoproteinemia; Adolescent; Adult; Child; Drug Therapy, Combination; Electrooculography; Electroretinography; Female; Follow-Up Studies; Humans; Hypobetalipoproteinemias; Male; Retinal Degeneration; Vitamin A; Vitamin E

2001

Other Studies

61 other study(ies) available for retinol and Retinal Degeneration

ArticleYear
Vitamin A cycle byproducts explain retinal damage and molecular changes thought to initiate retinal degeneration.
    Biology open, 2021, 11-15, Volume: 10, Issue:11

    Topics: Animals; Disease Models, Animal; Macular Degeneration; Rats; Retina; Retinal Degeneration; Retinal Pigment Epithelium; Retinoids; Vitamin A

2021
C20D3-Vitamin A Prevents Retinal Pigment Epithelium Atrophic Changes in a Mouse Model.
    Translational vision science & technology, 2021, 12-01, Volume: 10, Issue:14

    Topics: Animals; ATP-Binding Cassette Transporters; Macular Degeneration; Mice; Retinal Degeneration; Retinal Pigment Epithelium; Stargardt Disease; Vitamin A

2021
Long-term vitamin A supplementation in a preclinical mouse model for RhoD190N-associated retinitis pigmentosa.
    Human molecular genetics, 2022, 07-21, Volume: 31, Issue:14

    Topics: Animals; Dietary Supplements; Mice; Mutation; Retinal Degeneration; Retinitis Pigmentosa; Rhodopsin; Vitamin A

2022
Role of the
    International journal of molecular sciences, 2023, May-05, Volume: 24, Issue:9

    Topics: ATP-Binding Cassette Transporters; Gene Expression; Hair Follicle; Humans; Keratinocytes; Retinal Degeneration; Retinoids; Stem Cells; Vitamin A

2023
Saffron: Chemical Composition and Neuroprotective Activity.
    Molecules (Basel, Switzerland), 2020, Nov-29, Volume: 25, Issue:23

    Topics: Adenosine Triphosphate; Animals; Calcium; Carotenoids; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Crocus; Disease Models, Animal; Flowers; HEK293 Cells; Humans; Light; Mice; Neurodegenerative Diseases; Neuroprotective Agents; Plant Extracts; Rats, Sprague-Dawley; Receptors, Purinergic P2X7; Retina; Retinal Degeneration; Vitamin A

2020
Anti-Retinal Antibodies in Vitamin A Deficiency.
    Ophthalmic surgery, lasers & imaging retina, 2020, 12-01, Volume: 51, Issue:12

    Topics: Humans; Retina; Retinal Degeneration; Vitamin A; Vitamin A Deficiency

2020
Vitamin A and Daucus carota root extract mitigate STZ-induced diabetic retinal degeneration in Wistar albino rats by modulating neurotransmission and downregulation of apoptotic pathways.
    Journal of food biochemistry, 2021, Volume: 45, Issue:4

    Topics: Animals; Daucus carota; Diabetes Mellitus, Experimental; Down-Regulation; Male; Plant Extracts; Rats; Rats, Wistar; Retinal Degeneration; Synaptic Transmission; Vitamin A

2021
Saffron ameliorated motor symptoms, short life span and retinal degeneration in Parkinson's disease fly models.
    Gene, 2021, Oct-05, Volume: 799

    Topics: alpha-Synuclein; Animals; Animals, Genetically Modified; Carotenoids; Cell Line; Crocus; Disease Models, Animal; Drosophila melanogaster; Female; Humans; Longevity; Male; Motor Activity; Mutation; Neurons; Neuroprotective Agents; Parkinson Disease; Retinal Degeneration; Vitamin A

2021
Retinoid Metabolism in the Degeneration of Pten-Deficient Mouse Retinal Pigment Epithelium.
    Molecules and cells, 2021, Aug-31, Volume: 44, Issue:8

    Topics: Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Animals; Diet; Forkhead Transcription Factors; Mice, Transgenic; PTEN Phosphohydrolase; Retinal Degeneration; Retinal Pigment Epithelium; Retinoids; Vitamin A

2021
Vitamin A cycle byproducts impede dark adaptation.
    The Journal of biological chemistry, 2021, Volume: 297, Issue:3

    Topics: Aging; Animals; Dark Adaptation; Eye; Humans; Macular Degeneration; Male; Mice; Mice, Inbred ICR; Retina; Retinal Degeneration; Retinal Pigment Epithelium; Visual Acuity; Vitamin A

2021
A novel RPE65 inhibitor CU239 suppresses visual cycle and prevents retinal degeneration.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:7

    Topics: Animals; cis-trans-Isomerases; Diterpenes; Enzyme Inhibitors; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Retinal Degeneration; Retinyl Esters; Vision, Ocular; Vitamin A

2018
Abnormal Cannabidiol Modulates Vitamin A Metabolism by Acting as a Competitive Inhibitor of CRBP1.
    ACS chemical biology, 2019, 03-15, Volume: 14, Issue:3

    Topics: Amino Acid Sequence; Animals; Biological Transport; Cell Line; Drug Evaluation, Preclinical; Humans; Isomerism; Kinetics; Ligands; Light; Mice, Inbred BALB C; Oxidation-Reduction; Protein Binding; Resorcinols; Retinal Degeneration; Retinoids; Retinol-Binding Proteins, Cellular; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Vitamin A

2019
Vitamin A dimers trigger the protracted death of retinal pigment epithelium cells.
    Cell death & disease, 2014, Jul-24, Volume: 5

    Topics: Aged; Aged, 80 and over; Cell Death; Cells, Cultured; Dimerization; Epithelial Cells; Humans; Retinal Degeneration; Retinal Pigment Epithelium; Retinaldehyde; Vitamin A

2014
Chromophore supply rate-limits mammalian photoreceptor dark adaptation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Aug-20, Volume: 34, Issue:34

    Topics: Action Potentials; Animals; Dark Adaptation; Female; GTP-Binding Protein alpha Subunits; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuroglia; Orphan Nuclear Receptors; Photic Stimulation; Retina; Retinal Cone Photoreceptor Cells; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Rhodopsin; Time Factors; Transducin; Vitamin A; Vitamins

2014
Photoactivation-induced instability of rhodopsin mutants T4K and T17M in rod outer segments underlies retinal degeneration in X. laevis transgenic models of retinitis pigmentosa.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Oct-01, Volume: 34, Issue:40

    Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Humans; Light; Microscopy, Confocal; Mutation; Retinal Degeneration; Retinitis Pigmentosa; Rhodopsin; Rod Cell Outer Segment; Statistics, Nonparametric; Transfection; Vitamin A; Wheat Germ Agglutinins; Xenopus laevis

2014
Morphological and physiological retinal degeneration induced by intravenous delivery of vitamin A dimers in rabbits.
    Disease models & mechanisms, 2015, Volume: 8, Issue:2

    Topics: Animals; Choroid; Dimerization; Electroretinography; Injections, Intravenous; Photoreceptor Cells, Vertebrate; Rabbits; Retinal Degeneration; Retinal Neovascularization; Retinal Pigment Epithelium; Vitamin A

2015
The Rate of Vitamin A Dimerization in Lipofuscinogenesis, Fundus Autofluorescence, Retinal Senescence and Degeneration.
    Advances in experimental medicine and biology, 2016, Volume: 854

    Topics: Aging; Animals; Bruch Membrane; Dimerization; Fluorescence; Fundus Oculi; Humans; Lipofuscin; Models, Chemical; Molecular Structure; Retina; Retinal Degeneration; Retinal Pigment Epithelium; Vitamin A

2016
Interphotoreceptor Retinoid-Binding Protein Mitigates Cellular Oxidative Stress and Mitochondrial Dysfunction Induced by All-trans-Retinal.
    Investigative ophthalmology & visual science, 2016, Volume: 57, Issue:4

    Topics: ADAM Proteins; ADAM17 Protein; Animals; Cell Survival; Chromatography, High Pressure Liquid; Dark Adaptation; Eye Proteins; Immunoblotting; In Situ Nick-End Labeling; Light; Membrane Potential, Mitochondrial; Mice; Microscopy, Confocal; Mitochondrial Diseases; Nitric Oxide; Oxidative Stress; Photoreceptor Cells, Vertebrate; Reactive Oxygen Species; Retinal Degeneration; Retinol-Binding Proteins; Tumor Necrosis Factor-alpha; Vitamin A

2016
Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:9

    Topics: Animals; ATP-Binding Cassette Transporters; Dietary Supplements; Disease Models, Animal; Electroretinography; Lipofuscin; Liver; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Knockout; Pigment Epithelium of Eye; Retina; Retinal Degeneration; Spectrometry, Mass, Electrospray Ionization; Vitamin A

2008
Involvement of all-trans-retinal in acute light-induced retinopathy of mice.
    The Journal of biological chemistry, 2009, May-29, Volume: 284, Issue:22

    Topics: Acute Disease; Aging; Alcohol Oxidoreductases; Animals; Apoptosis; ATP-Binding Cassette Transporters; bcl-2-Associated X Protein; Caspases; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Chromatography, Liquid; Diterpenes; Ethanolamine; Humans; Light; Mass Spectrometry; Mice; Oxidation-Reduction; Rats; Retina; Retinal Degeneration; Retinal Diseases; Retinaldehyde; Retinyl Esters; Rhodopsin; Vitamin A

2009
Evaluation of 9-cis-retinyl acetate therapy in Rpe65-/- mice.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:9

    Topics: Animals; Behavior, Animal; Blindness; Carrier Proteins; cis-trans-Isomerases; Diterpenes; Electroretinography; Eye Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Pharmaceutical Vehicles; Photic Stimulation; Prodrugs; Retina; Retinal Degeneration; Retinoids; Retinyl Esters; Soybean Oil; Vitamin A

2009
The dependence of retinal degeneration caused by the rhodopsin P23H mutation on light exposure and vitamin a deprivation.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:3

    Topics: Animals; Animals, Genetically Modified; Light; Male; Microscopy, Confocal; Mutation, Missense; Photometry; Radiation Injuries, Experimental; Retina; Retinal Degeneration; Rhodopsin; Transgenes; Vitamin A; Vitamin A Deficiency; Xenopus laevis

2010
Crocetin prevents retinal degeneration induced by oxidative and endoplasmic reticulum stresses via inhibition of caspase activity.
    European journal of pharmacology, 2011, Jan-10, Volume: 650, Issue:1

    Topics: Administration, Oral; Animals; Carotenoids; Caspase Inhibitors; Caspases; Cell Death; Cell Line; Chromans; Endoplasmic Reticulum; Enzyme Activation; Enzyme Inhibitors; Fluoresceins; Gene Expression Regulation; Humans; Hydrogen Peroxide; Intracellular Space; Light; Male; Membrane Potential, Mitochondrial; Mice; Oxidation-Reduction; Oxidative Stress; Photoreceptor Cells, Vertebrate; Rats; Retinal Degeneration; Retinal Ganglion Cells; Tunicamycin; Vitamin A; Xanthenes

2011
C20-D3-vitamin A slows lipofuscin accumulation and electrophysiological retinal degeneration in a mouse model of Stargardt disease.
    The Journal of biological chemistry, 2011, Mar-11, Volume: 286, Issue:10

    Topics: Animals; ATP-Binding Cassette Transporters; Deuterium; Dimerization; Disease Models, Animal; Humans; Lipofuscin; Macular Degeneration; Mice; Mice, Mutant Strains; Retinal Degeneration; Stargardt Disease; Vitamin A; Vitamins

2011
Comparison of ocular pathologies in vitamin A-deficient mice and RPE65 gene knockout mice.
    Investigative ophthalmology & visual science, 2011, Jul-25, Volume: 52, Issue:8

    Topics: Acyltransferases; Animals; Blotting, Western; Carrier Proteins; Cell Count; Chromatography, High Pressure Liquid; cis-trans-Isomerases; Eye Proteins; Gene Expression; Injections, Intraperitoneal; Mice; Mice, Knockout; Microscopy, Electron, Scanning; Opsins; Phenotype; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Retinal Photoreceptor Cell Outer Segment; Retinal Pigment Epithelium; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin; Vitamin A; Vitamin A Deficiency

2011
Vitamin A supplementation ameliorates obesity-associated retinal degeneration in WNIN/Ob rats.
    Nutrition (Burbank, Los Angeles County, Calif.), 2013, Volume: 29, Issue:1

    Topics: Acetyltransferases; Animals; Arrestin; Base Sequence; DNA Primers; Fatty Acid Elongases; Gene Expression; Glial Fibrillary Acidic Protein; Immunohistochemistry; Male; Obesity; Rats; Retina; Retinal Degeneration; Rhodopsin; Vitamin A

2013
Autophagy protects the retina from light-induced degeneration.
    The Journal of biological chemistry, 2013, Mar-15, Volume: 288, Issue:11

    Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Apoptosis; Apoptosis Regulatory Proteins; ATP-Binding Cassette Transporters; Autophagy; Autophagy-Related Protein 7; Beclin-1; Cell Death; Cell Line; Humans; Light; Lysosomes; Membrane Proteins; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Photic Stimulation; Retina; Retinal Degeneration; Rhodopsin; Ubiquitin-Activating Enzymes; Ubiquitin-Protein Ligases; Vitamin A

2013
The chemical determination of vitamin D. I. The antimony trichloride reaction and the separation of vitamin D from vitamin A.
    Pharmaceutical bulletin, 1953, Volume: 1, Issue:3

    Topics: Antimony; Chlorides; Cholestanes; Retinal Degeneration; Vitamin A; Vitamin D; Vitamins

1953
11-Cis vitamin A in the prevention of retinal rod degeneration; an animal study.
    American journal of ophthalmology, 1958, Volume: 46, Issue:5 Pt 2

    Topics: Animals; Disease; Humans; Retina; Retinal Degeneration; Retinal Diseases; Vitamin A

1958
[The chromatographic separation of vitamin A and vitamin D].
    Pharmaceutisch weekblad, 1961, Feb-04, Volume: 96

    Topics: Ascorbic Acid; Cholestanes; Chromatography; Retinal Degeneration; Vitamin A; Vitamin D; Vitamins

1961
Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Sep-21, Volume: 101, Issue:38

    Topics: Animals; Ceruloplasmin; Crosses, Genetic; Macular Degeneration; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Retinal Degeneration; Reverse Transcriptase Polymerase Chain Reaction; Vitamin A

2004
Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases.
    Investigative ophthalmology & visual science, 2005, Volume: 46, Issue:12

    Topics: Animals; ATP-Binding Cassette Transporters; Chromatography, Gel; Chromatography, High Pressure Liquid; Dark Adaptation; Dose-Response Relationship, Drug; Electroretinography; Fenretinide; Lipofuscin; Mice; Mice, Inbred BALB C; Mice, Knockout; Microscopy, Fluorescence; Photic Stimulation; Pigment Epithelium of Eye; Prealbumin; Pyridinium Compounds; Retina; Retinal Degeneration; Retinoids; Retinol-Binding Proteins; Spectrometry, Fluorescence; Vitamin A

2005
RPE65 gene delivery restores isomerohydrolase activity and prevents early cone loss in Rpe65-/- mice.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:3

    Topics: Adenoviridae; Animals; Blotting, Western; Carrier Proteins; Chromatography, High Pressure Liquid; cis-trans-Isomerases; Dark Adaptation; Eye Proteins; Fluorescent Antibody Technique, Indirect; Gene Expression; Gene Expression Regulation, Enzymologic; Genetic Therapy; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Retinal Cone Photoreceptor Cells; Retinal Degeneration; Retinaldehyde; Reverse Transcriptase Polymerase Chain Reaction; Rod Opsins; Transducin; Vitamin A

2006
Abetalipoproteinemia-a case report.
    Metabolic and pediatric ophthalmology, 1981, Volume: 5, Issue:1

    Topics: Abetalipoproteinemia; Adolescent; Adult; Child; Child, Preschool; Eye Diseases; Female; Humans; Infant; Male; Night Blindness; Retinal Degeneration; Triglycerides; Vitamin A; Vitamin E

1981
Retinal reductase activity in rats with and without inherited retinal dystrophy.
    Experimental eye research, 1981, Volume: 33, Issue:4

    Topics: Aging; Alcohol Oxidoreductases; Animals; Cytochrome P450 Family 2; Darkness; Rats; Rats, Inbred Strains; Retina; Retinal Degeneration; Rhodopsin; Vitamin A

1981
Studies on experimentally induced retinal degeneration. 1. Effect of lipid peroxides on electroretinographic activity in the albino rabbit.
    Experimental eye research, 1982, Volume: 35, Issue:2

    Topics: Animals; Arachidonic Acids; Diterpenes; Docosahexaenoic Acids; Electroretinography; Leukotrienes; Linolenic Acids; Lipid Peroxides; Rabbits; Retina; Retinal Degeneration; Retinyl Esters; Vitamin A

1982
Combined vitamin A and E therapy prevents retinal electrophysiological deterioration in abetalipoproteinaemia.
    The British journal of ophthalmology, 1982, Volume: 66, Issue:12

    Topics: Abetalipoproteinemia; Adult; Child; Child, Preschool; Drug Therapy, Combination; Electrooculography; Electroretinography; Humans; Infant; Retinal Degeneration; Vitamin A; Vitamin E

1982
Retinal photoreceptor dystrophies: LI. Edward Jackson Memorial Lecture.
    American journal of ophthalmology, 1995, Volume: 120, Issue:5

    Topics: Humans; Photoreceptor Cells; Retinal Degeneration; Vitamin A; Vitamin E

1995
Night blindness in Sorsby's fundus dystrophy reversed by vitamin A.
    Nature genetics, 1995, Volume: 11, Issue:1

    Topics: Adult; Bruch Membrane; Diffusion; DNA Mutational Analysis; Eye Proteins; Female; Fundus Oculi; Humans; Male; Middle Aged; Night Blindness; Pedigree; Point Mutation; Polymorphism, Single-Stranded Conformational; Proteins; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Scotoma; Tissue Inhibitor of Metalloproteinase-3; Vitamin A

1995
Bright environmental light accelerates rhodopsin depletion in retinoid-deprived rats.
    Investigative ophthalmology & visual science, 1993, Volume: 34, Issue:6

    Topics: Animals; Cell Count; Cell Death; Dark Adaptation; Diet; Disease Models, Animal; Light; Male; Photoreceptor Cells; Rats; Rats, Inbred F344; Retinal Degeneration; Rhodopsin; Rod Cell Outer Segment; Vitamin A; Vitamin A Deficiency

1993
Mechanisms of photoreceptor death in retinal degenerations: from the cell biology of the 1990s to the ophthalmology of the 21st century?
    Archives of ophthalmology (Chicago, Ill. : 1960), 1996, Volume: 114, Issue:9

    Topics: Cell Death; Humans; Photoreceptor Cells; Retinal Degeneration; Vitamin A

1996
Helicoid peripapillary chorioretinal degeneration in abetalipoproteinemia.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:2

    Topics: Abetalipoproteinemia; Adult; Atrophy; Choroid; Choroid Diseases; Female; Fluorescein Angiography; Fundus Oculi; Humans; Optic Disk; Retina; Retinal Degeneration; Vitamin A; Vitamin E

1998
Phenotypic marker for early disease detection in dominant late-onset retinal degeneration.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:8

    Topics: Adult; Age of Onset; Aged; Aged, 80 and over; Biomarkers; Dark Adaptation; Electroretinography; Female; Genes, Dominant; Humans; Male; Middle Aged; Pedigree; Phenotype; Retina; Retinal Degeneration; Risk Factors; Visual Acuity; Vitamin A

2001
Further study of the relation of vitamin A to retinal degenerations.
    Transactions of the ophthalmological societies of the United Kingdom, 1978, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Female; Humans; Male; Middle Aged; Retinal Degeneration; Retinal Detachment; Retinitis Pigmentosa; Vitamin A

1978
Vitamin A receptors. Retinoic acid binding in ocular tissues.
    The Biochemical journal, 1978, Jan-01, Volume: 169, Issue:1

    Topics: Animals; Binding Sites; Cattle; Centrifugation, Density Gradient; Chick Embryo; Chickens; Cornea; Eye; Haplorhini; Humans; Pigment Epithelium of Eye; Rats; Receptors, Drug; Retina; Retinal Degeneration; Tretinoin; Vitamin A

1978
[Pathophysiology of tapeto-retinal degenerations of various etiologies].
    Bericht uber die Zusammenkunft. Deutsche Ophthalmologische Gesellschaft, 1977, Volume: 74

    Topics: Electrooculography; Electroretinography; Eye Foreign Bodies; Photoreceptor Cells; Retinal Degeneration; Vitamin A

1977
A therapeutic trial of vitamin A in patients with pigmentary retinal degenerations: a negative study.
    Advances in experimental medicine and biology, 1977, Volume: 77

    Topics: Adolescent; Adult; Aged; Child; Electroretinography; Humans; Macular Degeneration; Middle Aged; Retinal Degeneration; Retinitis Pigmentosa; Vision, Ocular; Visual Fields; Vitamin A

1977
Long-term management of abetalipoproteinaemia. Possible role for vitamin E.
    Archives of disease in childhood, 1977, Volume: 52, Issue:3

    Topics: Abetalipoproteinemia; Child; Female; Follow-Up Studies; Growth; Humans; Infant; Male; Neurologic Manifestations; Retinal Degeneration; Vitamin A; Vitamin E

1977
The effects of excess vitamin A and acetylsalicylic acid on the stability of rat retinal lysosomes in vivo.
    Experimental eye research, 1977, Volume: 24, Issue:3

    Topics: Animals; Aspirin; Galactosidases; Hexosaminidases; Lysosomes; Rats; Retina; Retinal Degeneration; Vitamin A

1977
The role of retinol in, and the action of anti-inflammatory drugs on, hereditary retinal degeneration.
    Advances in experimental medicine and biology, 1975, Volume: 53

    Topics: Acid Phosphatase; Animals; Aspirin; Darkness; DNA; Female; Galactosidases; Genes, Recessive; Glucuronidase; Hexosaminidases; In Vitro Techniques; Light; Lysosomes; Male; Rats; Retina; Retinal Degeneration; RNA; Sensory Deprivation; Vitamin A

1975
The effect of retinol and acetylsalicylic acid on the release of lysosomal enzymes from rat retina in vitro.
    Experimental eye research, 1975, Volume: 20, Issue:1

    Topics: Animals; Aspirin; Female; Galactosidases; Glucuronidase; Hexosaminidases; In Vitro Techniques; Lysosomes; Male; Rats; Retina; Retinal Degeneration; Stimulation, Chemical; Vitamin A

1975
Hereditary retinal dystrophy in the rat: rhodopsin, retinol, vitamin A deficiency.
    Experimental eye research, 1975, Volume: 21, Issue:4

    Topics: Age Factors; Animals; Darkness; Diet; Light; Pigment Epithelium of Eye; Rats; Retina; Retinal Degeneration; Retinal Pigments; Rhodopsin; Time Factors; Vitamin A; Vitamin A Deficiency

1975
[Letter: Humid senile macular degeneration].
    Deutsche medizinische Wochenschrift (1946), 1976, Mar-26, Volume: 101, Issue:13

    Topics: Humans; Light Coagulation; Macular Degeneration; Retinal Degeneration; Vitamin A; Vitamin E

1976
Retinol and retinyl esters in pigment epithelium of rats with inherited retinal degeneration.
    Experientia, 1976, Feb-15, Volume: 32, Issue:2

    Topics: Age Factors; Animals; Pigment Epithelium of Eye; Rats; Retinal Degeneration; Vitamin A

1976
Interstitial retinol-binding protein in the interphotoreceptor matrix of normal and dystrophic rats.
    Progress in clinical and biological research, 1985, Volume: 190

    Topics: Animals; Extracellular Matrix; Eye Proteins; Molecular Weight; Photoreceptor Cells; Pigment Epithelium of Eye; Rats; Rats, Mutant Strains; Retinal Degeneration; Retinol-Binding Proteins; Rhodopsin; Vitamin A

1985
IRBP and retinyl ester in the rd mutant retina.
    Progress in clinical and biological research, 1985, Volume: 190

    Topics: Animals; Eye Proteins; Mice; Mice, Mutant Strains; Retina; Retinal Degeneration; Retinol-Binding Proteins; Vitamin A

1985
Biochemistry of retinal dystrophy.
    Journal of medical genetics, 1970, Volume: 7, Issue:3

    Topics: Adenosine Triphosphatases; Alcohol Oxidoreductases; Carbohydrate Metabolism; Hexosephosphates; Humans; Isoenzymes; Microscopy, Electron; Proteins; Retinal Degeneration; Retinal Pigments; Vitamin A

1970
[Treatment of senile degenerative maculopathies by etaretin. Prospects of success and economical points of view (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1974, Volume: 165, Issue:1

    Topics: Age Factors; Aged; Animals; Drug Therapy, Combination; Female; Humans; Macula Lutea; Male; Middle Aged; Phospholipids; Retina; Retinal Degeneration; Swine; Time Factors; Tissue Extracts; Visual Acuity; Vitamin A; Vitamin E

1974
Cone and rod responses in nutritionally induced retinal degeneration in the cat.
    Investigative ophthalmology, 1973, Volume: 12, Issue:9

    Topics: Animals; Cats; Dark Adaptation; Diet; Disease Models, Animal; Electroretinography; Evoked Potentials; Fluorometry; Fundus Oculi; Ophthalmoscopy; Photic Stimulation; Photography; Photoreceptor Cells; Retina; Retinal Degeneration; Vitamin A

1973
[Letter: Macula degeneration].
    Medizinische Klinik, 1973, Sep-21, Volume: 68, Issue:38

    Topics: Humans; Macula Lutea; Retinal Degeneration; Retinal Diseases; Rutin; Vitamin A; Vitamin E

1973
[Retinal degeneration in rat. Its dependence on intensity of illumination and vitamin A in food].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:6

    Topics: Animals; Female; Light; Male; Rats; Retina; Retinal Degeneration; Sex Factors; Vitamin A

1970