retinol has been researched along with Abnormalities, Drug-Induced in 249 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 172 (69.08) | 18.7374 |
| 1990's | 52 (20.88) | 18.2507 |
| 2000's | 19 (7.63) | 29.6817 |
| 2010's | 6 (2.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cherr, GN; Ellis-Hutchings, RG; Hanna, LA; Keen, CL | 1 |
| Mulvihill, A; Tandon, A | 1 |
| Aoki, T; Dodo, T; Fukuta, T; Hirano, K; Hirose, T; Horiba, T; Kato, E; Katsutani, N; Kojima, C; Maeda, M; Mineshima, H; Okuda, Y; Shiraishi, I; Uchida, K | 1 |
| Babu, TA; Sharmila, V | 1 |
| Hashemi Soteh, MB; Rahimi, F; Rezaei, N | 1 |
| Aoki, T; Fukuta, T; Kato, E; Matsuno, Y; Mineshima, H; Mori, C; Uchida, K | 1 |
| Huang, Y; Zheng, S | 1 |
| Dowling, DD; Duerbeck, NB | 1 |
| Chang, CH; Chen, KC; Chuang, CM; Hsieh, CL; Peng, CC; Peng, RY; Wang, HE | 1 |
| Diez-Pardo, JA; Gonzalez, S; Tovar, JA; Yu, J | 1 |
| Diez-Pardo, JA; Gonzalez, S; Martinez, L; Tovar, JA; Yu, J | 1 |
| DELMAS, A; GIROUD, A; MARTINET, M | 1 |
| MAUER, I | 1 |
| BENITO-ARRANZ, S | 1 |
| BIAGI, GL | 1 |
| DERONCAGLIOLO, MC; REBOLLO, MA | 1 |
| CAHEN, R; MONTAGNE, J; SAUTAI, M | 1 |
| TAKEKOSHI, S | 1 |
| GIROUD, A | 1 |
| KALTER, H | 1 |
| KAMEYAMA, Y; MURAKAMI, U | 2 |
| KNUDSEN, PA | 6 |
| FERM, VH; MARIN-PADILLA, M | 1 |
| MASI, PL; PIERLEONI, P; TOLLARO, I; VICHI, F | 1 |
| Freytag, TL; Liu, SM; Morris, JG; Rogers, QR | 1 |
| Blankenship, AL; Coady, KK; Giesy, JP; Hilscherova, K; Nie, M; Trosko, JE; Upham, BL | 1 |
| Emmanouil-Nikoloussi, EN; Foroglou, NG; Kerameos-Foroglou, CH; Thliveris, JA | 1 |
| Elmazar, MM; Nau, H | 1 |
| Orlow, SJ; Van Zander, J | 1 |
| Akahori, F; Hisamatsu, S; Inomata, T; Kashiwazaki, N; Kiuchi, A; Ninomiya, H; Takizawa, A; Yoshida, T | 1 |
| Ali-Khan, SE; Hales, BF | 1 |
| Cahu, CL; Gisbert, E; Moriceau, J; Villeneuve, LA; Zambonino Infante, JL | 1 |
| Rogers, JM | 1 |
| Correia-Pinto, J; Gonzaga, S; Moura, RS; Nogueira-Silva, C; Ohlmeier, S; Santos, M | 1 |
| Lotosh, EA | 1 |
| Abrams, RG; Kronman, JH | 1 |
| Sharpe, R | 1 |
| Davis, LA; Sadler, TW | 1 |
| Smithells, RW | 1 |
| Harris, R; Read, AP | 1 |
| Hall, JG | 2 |
| Dhouailly, D; Maden, M; Summerbell, D | 1 |
| Willhite, CC | 1 |
| Azoubel, R; Lopes, RA; Souza, ML | 1 |
| Garde, T; Gropp, A; Krause, G; Putz, B | 1 |
| Padmanabhan, R; Singh, G; Singh, S | 2 |
| Nakamura, H; Yasuda, M | 1 |
| Klein, NW; Plenefisch, JD; Steele, CE | 1 |
| Nigra, T; Windhorst, DB | 1 |
| Henderson, JM | 1 |
| Kamm, JJ | 1 |
| Huntington, HW; Smith, MT | 1 |
| Lavery, JP | 1 |
| Milad, M; Sabet, S | 1 |
| Mannino, S; Milunsky, A; Moore, LL; Nguyen, US; Rothman, KJ; Singer, MR | 1 |
| Erickson, JD; Oakley, GP | 1 |
| Mondry, M; Nau, H; Plum, C; Spohr, HL; Tzimas, G | 1 |
| Juchau, MR; Kimelman, D; Kraft, JC | 1 |
| Creech Kraft, J; Juchau, MR; Kimelman, D | 1 |
| Kolb, E | 1 |
| Hall, BL; Kimelman, D; Kraft, JC; Privalsky, ML; Schuh, TJ | 1 |
| Domenech Mateu, JM; Gonzalez Compta, X | 1 |
| Black, TN; Collins, TF; Flynn, T; O'Donnell, MW; Shackelford, M; Sundaresan, PR; Ware, SE; Welsh, JJ; Whitby, KE | 1 |
| Crosland, G | 1 |
| Lipson, AH; Webster, WS | 1 |
| Khoury, MJ; Moore, CA; Mulinare, J | 1 |
| Lammer, EJ; Mitchell, AA; Werler, MM | 1 |
| Brent, RL; Hendrickx, AG; Holmes, LB; Miller, RK | 1 |
| Moore, C; Mulinare, J; Watkins, M | 1 |
| Challem, JJ | 1 |
| Hunt, JR | 1 |
| Biesalski, HK; El Hanafy, M; Hemmes, C; Stofft, E; Weiser, H; Zschaebitz, H | 1 |
| Block, G; Lammer, EJ; Shaw, GM; Wasserman, CR | 1 |
| Deslypere, JP; Hulshof, KF; van den Berg, H | 1 |
| Dolan, CR; Donlan, MA; Friedman, JM; Polifka, JE | 1 |
| Erdoğan, D; Kadioğlu, D; Peker, T | 1 |
| Ferretti, P; Ghosh, S; Thorogood, P | 1 |
| Presbury, D | 1 |
| Monga, M | 1 |
| Barua, AB | 1 |
| Guillonneau, M; Jacqz-Aigrain, E | 1 |
| Kramer, B; Lefkowitz, B | 1 |
| Jick, H | 1 |
| Czeizel, AE; Rockenbauer, M | 1 |
| Hartmann, S; Hummler, H; Wiegand, UW | 1 |
| Aclimandos, WA; Baker, AJ; Bentley, C; Bird, AC; Davies, A; Hingorani, M; Mieli-Vergani, G; Nischal, KK; Vivian, A | 1 |
| Addis, A; Bonati, M; Caramelli, L; Carlier, P; Clementi, M; Elephant, E; Finardi, A; Garbis, H; Mastroiacovo, P; Mazzone, T; Ornoy, A; Robert, E; Rodríguez-Pinilla, E; Schaffer, C; Vial, T | 1 |
| Barlow, SM; Dolk, HM; Hummler, H; Nau, H | 1 |
| Bolon, B; LaBorde, JB; Pauken, CM | 1 |
| Collins, MD; Derguini, F; Mao, GE | 1 |
| Fujita, S; Ghonim, MH; Hadid, AH; Iwata, H; Kazusaka, A; Khlood, EB; Kon, Y; Miyoshi, H; Moustafe, EK | 1 |
| Das, P; Mohanty-Hejmadi, P | 1 |
| Eckhoff, C; Grant, J; Maggio-Price, L; Manley, N; Mulder, GB; Schmidt, K; Zeng, W | 1 |
| Arnhold, T; Elmazar, MM; Nau, H | 1 |
| Kelleher, PC; Smith, CJ | 1 |
| Dormans, JA; Geelen, JA; Peters, PW | 1 |
| Bailey, J; Bainbridge, SR; Hebert, CN; James, RK; Lewis, G; Wells, DE; Wrathall, AE | 1 |
| Eckhert, CD; Hurley, LS | 1 |
| Kochhar, DM | 5 |
| Woollam, DH | 1 |
| Lite, S; May, DL; Nanda, R | 1 |
| Merker, HJ | 1 |
| Geelen, JA | 4 |
| Fantel, AG; Moffett, BC; Newell-Morris, LL; Shepard, TH | 1 |
| Dhermy, P; Offret, G | 1 |
| Mahran, ZY; Nawar, NN; Sakla, FB | 1 |
| Ferm, RR; Ferm, VH | 1 |
| Marin-Padilla, M | 2 |
| Morriss, GM; Steele, CE | 2 |
| Agnish, ND; Kochhar, DM | 1 |
| Ajisaka, F | 1 |
| Duncan, JR; Hurley, LS | 1 |
| Fraser, BA; Travill, AA | 1 |
| Klein, D; Mounoud, RL; Weber, F | 1 |
| Kochlar, DM | 1 |
| Nanda, R; Romeo, D | 1 |
| Nakamura, H | 2 |
| Love, AM; Vickers, TH | 2 |
| Morriss, GM | 3 |
| Pilotti, G | 1 |
| Lupien, PJ; Savoie, LL | 1 |
| Baccetti, T; Franchi, L; Pierleoni, P; Tollaro, I | 1 |
| Cornel, MC; de Jong-van den Berg, LT; de Smet, PA; Knijn, GJ | 1 |
| Snodgrass, SR | 1 |
| Bochert, G; Chahoud, I; Collins, MD; Eckhoff, C; Nau, H | 1 |
| Aranyi, C; Gaworski, CL; Heck, JD; Vollmuth, TA; York, RG | 1 |
| Evans, K; Hickey-Dwyer, MU | 1 |
| Noirfalise, A | 1 |
| Sanders, TA | 1 |
| Endo, A; Watanabe, T | 1 |
| Ruckman, RN | 1 |
| Hathcock, JN; Hattan, DG; Jenkins, MY; McDonald, JT; Sundaresan, PR; Wilkening, VL | 1 |
| Nelson, M | 1 |
| Rutter, JM | 1 |
| Lammer, EJ; Mitchell, AA; Rosenberg, L; Werler, MM | 1 |
| Martínez-Frías, ML; Salvador, J | 2 |
| Underwood, BA | 1 |
| Kochhar, DM; Satre, MA | 1 |
| Bochert, G; Chahoud, I; Eckhoff, C; Löfberg, B; Nau, H | 1 |
| Balogh-Nair, V; Willhite, CC | 1 |
| Cicurel, L; Schmid, BP | 1 |
| Kochhar, DM; Penner, JD; Satre, MA | 1 |
| Pillans, PI | 1 |
| Dickinson, A | 1 |
| Folb, PI; Pillans, PI; Ponzi, SF | 1 |
| Laschinski, G; Spielmann, H | 1 |
| Kelsey, FO; Rosa, FW; Wilk, AL | 1 |
| Calabro, A; Lungarotti, MS; Mariani, T; Marinelli, D | 1 |
| Eto, K; Takakubo, F | 1 |
| Beeley, L | 1 |
| Kay, ED | 1 |
| Slavkin, HC | 1 |
| Olson, JA | 1 |
| Fantel, AG; Mirkes, PE; Shepard, TH | 1 |
| Nishimura, H; Nomura, T; Shiota, K; Uwabe, C | 1 |
| Edwards, JR; Newall, DR | 1 |
| Seller, MJ | 1 |
| Morriss, GM; Thomson, AD | 1 |
| Abramovich, A; Devoto, FC | 2 |
| Nanda, R | 3 |
| Schimmelpfennig, K | 1 |
| Jansen, HW; Nanda, R; van der Linden, FP | 1 |
| Eguchi, Y; Hashimoto, Y; Morikawa, Y | 1 |
| Derr, JE; King, CT; Steffek, AJ | 1 |
| Barrow, MV; Rowland, CA | 1 |
| Gal, I | 1 |
| Stivers, FE; Yarington, CT | 1 |
| Aydelotte, MB; Kochhar, DM | 1 |
| Hellenriegel, KP; Reuter, H | 1 |
| Berry, CL; Germain, J | 1 |
| Shenefelt, RE | 2 |
| Nolen, GA | 2 |
| Poswillo, DE | 1 |
| Coates, V; Goudie, C; March, BE | 1 |
| Brunner, RL; Butcher, RE; Kimmel, CA; Roth, T | 1 |
| Khemmani, M; Monie, IW | 1 |
| Gibbon, J; Hutchings, DE; Kaufman, MA | 1 |
| Merker, HJ; Schweichel, JU | 1 |
| Muenter, MD | 1 |
| Schorah, CJ; Smithells, RW; Wild, J | 1 |
| Iles, CA; Leck, I; Sharman, IM; Toe, T; Wadsworth, GR | 1 |
| Bernhardt, IB; Dorsey, DJ | 1 |
| Briggs, MH | 1 |
| Ross, LM; Walker, BE | 1 |
| Dyban, AP | 1 |
| Seidler, M | 1 |
| Johnson, EM; Kochhar, DM | 1 |
| Roussel, C; Tuchmann-Duplessis, H | 1 |
| Eguchi, Y; Hashimoto, Y; Morikawa, Y; Suzuki, S | 1 |
| Abramovici, A | 1 |
| Luz, D; Mayer-Rosa, P; Wegner, G | 1 |
| Soliman, MK | 1 |
| Malakhovskiĭ, VG | 1 |
| Krasitskaia, OP | 1 |
| Knudson, PA | 1 |
| Ritter, W; Tetsch, P | 1 |
| Yamaguchi, T | 1 |
| Komatsu, S | 1 |
| Pellanda, EB | 1 |
| Ferm, VH | 2 |
| Auroux, M; Roussel, C | 1 |
| Beck, F; Lloyd, JB | 1 |
| Robens, JF | 1 |
| Malakhovskiĭ, VG; Prozorovskiĭ, VB | 1 |
| Craft, I; Gal, I; Parkinson, C | 1 |
| Miyazaki, M; Takekoshi, S | 1 |
| Boström, H; Kochhar, DM; Larsson, KS | 1 |
| Clark, L; Seawright, AA | 1 |
| Takacs, E; Warkany, J | 1 |
| Lattanzio, G; Masignani, M; Scapecchi, G | 1 |
| Moore, T; Pryse-Davies, J; Sharman, IM | 1 |
| Gontzea, I | 1 |
| Clegg, DJ | 1 |
| Pilotti, G; Scorta, A | 1 |
| Kameyama, Y | 1 |
| Liotti, FS; Negri, PL | 2 |
23 review(s) available for retinol and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Ocular teratogens: old acquaintances and new dangers.
Topics: Abnormalities, Drug-Induced; Cocaine; Eye Abnormalities; Female; Fetal Alcohol Spectrum Disorders; Humans; Male; Opiate Alkaloids; Pregnancy; Teratogens; Vitamin A | 2009 |
Vitamin A: too much of a good thing?
Topics: Abnormalities, Drug-Induced; beta Carotene; Clinical Trials as Topic; Dietary Supplements; Dose-Response Relationship, Drug; Female; Humans; Hypervitaminosis A; Infant, Newborn; Nonprescription Drugs; Perinatal Care; Pregnancy; Pregnancy Complications; United States; United States Food and Drug Administration; Vitamin A; Vitamin A Deficiency; Vitamins | 2012 |
[CONGENITAL ABNORMALITIES CAUSED BY CHEMICAL AGENTS AND DEFICIENCIES. I].
Topics: Abnormalities, Drug-Induced; Alkaloids; Amino Acids; Anti-Bacterial Agents; Antibodies; Congenital Abnormalities; Enzymes; Galactose; Hormones; Hypoglycemic Agents; Metals; Methylene Blue; Prochlorperazine; Sulfanilamide; Sulfanilamides; Sulfonamides; Thalidomide; Toxicology; Trypan Blue; Vitamin A | 1964 |
Efficacy and safety of oral retinoids in psoriasis.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Combined Modality Therapy; Humans; Phototherapy; Psoriasis; Retinoids; Ultraviolet Rays; Vitamin A | 2005 |
Toxicology, carcinogenicity, and teratogenicity of some orally administered retinoids.
Topics: Abnormalities, Drug-Induced; Animals; Dogs; Female; Mice; Mutagenicity Tests; Neoplasms; Pregnancy; Rats; Reproduction; Vitamin A | 1982 |
[The problem of a high content of vitamin A in the liver of calves, cattle, sheep and swine for the consumer. Amount of accumulation and mechanism of teratogenic effect (review article)].
Topics: Abnormalities, Drug-Induced; Animals; Cattle; Drug Residues; Female; Humans; Hypervitaminosis A; Liver; Meat; Mice; Pregnancy; Pregnancy Complications; Sheep; Swine; Vitamin A | 1994 |
Vitamin A and its congeners.
Topics: Abnormalities, Drug-Induced; Acitretin; Etretinate; Female; Humans; Isotretinoin; Pregnancy; Retinoids; Tretinoin; Vitamin A | 1997 |
Retinoyl beta-glucuronide: a biologically active form of vitamin A.
Topics: Abnormalities, Drug-Induced; Animals; Female; Intestinal Absorption; Pregnancy; Tretinoin; Vitamin A | 1997 |
[Teratogenic effects of vitamin A and its derivates].
Topics: Abnormalities, Drug-Induced; Acitretin; Animals; Female; Humans; Isotretinoin; Keratolytic Agents; Pregnancy; Retinoids; Teratogens; Vitamin A | 1997 |
The effect of vitamin A on the development of the craniofacial complex--an update for practitioners.
Topics: Abnormalities, Drug-Induced; Animals; Embryonic and Fetal Development; Face; Humans; Neural Crest; Skull; Vitamin A | 1992 |
Safety of vitamin A: recent results.
Topics: Abnormalities, Drug-Induced; Animals; Clinical Trials as Topic; Dietary Supplements; Female; Humans; Isotretinoin; Liver; Macaca fascicularis; Pregnancy; Tretinoin; Vitamin A | 1998 |
Dietary vitamin A and teratogenic risk: European Teratology Society discussion paper.
Topics: Abnormalities, Drug-Induced; Animals; Diet; Dietary Supplements; Disease Models, Animal; Female; Humans; Nutrition Policy; Pregnancy; Risk Factors; Vitamin A | 1999 |
Considerations on the problem of critical period during the development of limb skeleton.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Bone and Bones; Cartilage; Cell Division; Collagen; Embryo Implantation; Extremities; Female; Limb Deformities, Congenital; Mercaptopurine; Mesoderm; Mice; Osteogenesis; Proteoglycans; Teratogens; Time Factors; Vitamin A | 1977 |
Hypervitaminosis A induced teratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Brain; Cleft Palate; Cricetinae; Embryo, Mammalian; Female; Gestational Age; Mice; Organ Specificity; Pregnancy; Rabbits; Rats; Species Specificity; Teratogens; Vitamin A | 1979 |
[A case of Goldenhar syndrome: acute vitamin A intoxication in the mother during pregnancy].
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Branchial Region; Child, Preschool; Dermoid Cyst; Eye Abnormalities; Face; Female; Humans; Male; Mandibulofacial Dysostosis; Pregnancy; Syndrome; Vitamin A | 1975 |
[A current update on the etiopathogenesis of palatoschisis].
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Glucocorticoids; Humans; Palate; Vitamin A | 1992 |
[Teratogenic risks of high-dosage vitamin A].
Topics: Abnormalities, Drug-Induced; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Legislation, Drug; Netherlands; Pregnancy; Retinoids; Teratogens; Vitamin A | 1992 |
Vitamin neurotoxicity.
Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Avitaminosis; Blood-Brain Barrier; Carrier Proteins; Coenzymes; Drug Interactions; Folic Acid; Humans; Injections, Spinal; Liver; Methotrexate; Nervous System Diseases; Oxidation-Reduction; Pseudotumor Cerebri; Pyridoxine; Self Medication; Vitamin A; Vitamins | 1992 |
Cardiovascular defects associated with alcohol, retinoic acid, and other agents.
Topics: Abnormalities, Drug-Induced; Animals; Ethanol; Heart Defects, Congenital; Humans; Teratogens; Tretinoin; Vitamin A | 1990 |
Evaluation of vitamin A toxicity.
Topics: Abnormalities, Drug-Induced; Animals; beta Carotene; Carotenoids; Dose-Response Relationship, Drug; Drug Synergism; Humans; Hypervitaminosis A; Liver Diseases; Vitamin A | 1990 |
Teratogenicity of vitamin A.
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Pregnancy; Vitamin A | 1989 |
Adverse effects of drugs in the first trimester of pregnancy.
Topics: Abnormalities, Drug-Induced; Anesthetics; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Antiemetics; Antineoplastic Agents; Female; Fetal Alcohol Spectrum Disorders; Gonadal Steroid Hormones; Humans; Hypnotics and Sedatives; Lithium; Pregnancy; Pregnancy Trimester, First; Psychotropic Drugs; Rubella Vaccine; Smoking; Vitamin A | 1986 |
[Some current problems of experimental teratology].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Female; Hypoxia; Methods; Mice; Pregnancy; Rabbits; Rats; Species Specificity; Statistics as Topic; Thalidomide; Time Factors; Uracil; Vitamin A | 1967 |
2 trial(s) available for retinol and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Present and future use of retinoids in Australia.
Topics: Abnormalities, Drug-Induced; Australia; Clinical Trials as Topic; Etretinate; Female; Humans; Isotretinoin; Neoplasms; Pregnancy; Skin Diseases; Tretinoin; Vitamin A | 1981 |
High vitamin A intake in early pregnancy and major malformations: a multicenter prospective controlled study.
Topics: Abnormalities, Drug-Induced; Cohort Studies; Dose-Response Relationship, Drug; Female; Humans; Pregnancy; Pregnancy Trimester, First; Prevalence; Prospective Studies; Vitamin A | 1999 |
224 other study(ies) available for retinol and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
The effects of marginal maternal vitamin A status on penta-brominated diphenyl ether mixture-induced alterations in maternal and conceptal vitamin A and fetal development in the Sprague Dawley rat.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animal Feed; Animals; Bone Development; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Female; Fetal Development; Flame Retardants; Gene Expression Regulation, Developmental; Gestational Age; Halogenated Diphenyl Ethers; Liver; Maternal Exposure; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinol-Binding Proteins, Cellular; Thyroid Gland; Thyroid Hormones; Vitamin A; Vitamin A Deficiency | 2009 |
Increases in discontinuous rib cartilage and fused carpal bone in rat fetuses exposed to the teratogens, busulfan, acetazolamide, vitamin A, and ketoconazole.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Busulfan; Carpal Bones; Cartilage; Diterpenes; Dose-Response Relationship, Drug; Female; Fetal Death; Fetal Development; Fetal Resorption; Fetal Weight; Fetus; Ketoconazole; Pregnancy; Random Allocation; Rats; Retinyl Esters; Ribs; Teratogens; Vitamin A | 2010 |
Vitamin A supplementation in late pregnancy can decrease the incidence of bronchopulmonary dysplasia in newborns.
Topics: Abnormalities, Drug-Induced; Bronchopulmonary Dysplasia; Female; Fetal Growth Retardation; Gestational Age; Humans; Immunologic Deficiency Syndromes; Infant, Low Birth Weight; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Vitamin A; Vitamin A Deficiency | 2010 |
Effects of limited doses of retinyl palmitate at the critical time of limb morphogenesis in mouse embryos.
Topics: Abnormalities, Drug-Induced; Animals; Anticarcinogenic Agents; Diterpenes; Drug Administration Schedule; Embryo Loss; Embryo, Mammalian; Extremities; Female; Gestational Age; Injections, Intraperitoneal; Lower Extremity Deformities, Congenital; Mice; Morphogenesis; Pregnancy; Retinyl Esters; Teratoma; Upper Extremity Deformities, Congenital; Vitamin A | 2009 |
Malformation spectrum induced by ketoconazole after single administration to pregnant rats during the critical period - comparison with vitamin A-induced malformation spectrum.
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Fetal Diseases; Fetus; Gestational Age; Ketoconazole; Maternal Exposure; Organogenesis; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens; Time Factors; Vitamin A | 2012 |
The effect of vitamin A deficiency during pregnancy on anorectal malformations.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anal Canal; Animals; Anus, Imperforate; Diet; Enteric Nervous System; Ethylenethiourea; Female; Gene Expression Regulation, Developmental; Nerve Tissue Proteins; Neurons; Pregnancy; Pregnancy Complications; Random Allocation; Rats; Rats, Sprague-Dawley; Rectum; S100 Proteins; Tail; Teratogens; Ubiquitin Thiolesterase; Vitamin A; Vitamin A Deficiency | 2011 |
Valproic acid downregulates RBP4 and elicits hypervitaminosis A-teratogenesis--a kinetic analysis on retinol/retinoic acid homeostatic system.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Embryonic Development; Histone Deacetylases; Homeostasis; Hydrogen Peroxide; Hypervitaminosis A; Kinetics; Phenotype; Proteomics; Retinol-Binding Proteins, Plasma; Superoxide Dismutase; Teratogens; Valproic Acid; Vitamin A | 2012 |
Effects of vitamin A on malformations of neural-crest-controlled organs induced by nitrofen in rats.
Topics: Abnormalities, Drug-Induced; Animals; Female; Herbicides; Neural Crest; Phenyl Ethers; Pregnancy; Rats; Rats, Sprague-Dawley; Vitamin A | 2002 |
Effects of retinoic acid on the neural crest-controlled organs of fetal rats.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Drug Evaluation, Preclinical; Female; Fetus; Models, Animal; Neural Crest; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Tretinoin; Vitamin A | 2003 |
[CYCLOCEPHALUS: MORPHOGENESIS AND MECHANISM OF ITS PRODUCTION].
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Animals; Female; Humans; Mice; Morphogenesis; Pharmacology; Pregnancy; Research; Toxicology; Vitamin A | 1963 |
VITAMIN A-INDUCED CONGENITAL DEFECTS IN HAIRLESS MICE.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Anophthalmos; Cerebral Hemorrhage; Cleft Palate; Female; Humans; Mice; Mice, Hairless; Pregnancy; Research; Skull; Toxicology; Vitamin A | 1964 |
[THE PERICOMMISSURAL ORGAN IN EXPERIMENTAL HYDROCEPHALUS].
Topics: Abnormalities, Drug-Induced; Aldosterone; Animals, Newborn; Choroid Plexus; Diencephalon; Fetal Diseases; Histocytochemistry; Hydrocephalus; Pathology; Physiology; Pregnancy; Pregnancy, Animal; Rabbits; Research; Sodium; Toxicology; Vitamin A | 1963 |
[MENINGOVASCULAR ALTERATIONS IN THE MALFORMATIONS OF THE CENTRAL NERVOUS SYSTEM PRODUCED EXPERIMENTALLY].
Topics: Abnormalities, Drug-Induced; Animals; Arnold-Chiari Malformation; Central Nervous System; Cerebrovascular Circulation; Female; Meninges; Pathology; Pregnancy; Pregnancy, Animal; Rats; Research; Vitamin A | 1963 |
[RESEARCH ON THE TERATOGENIC EFFECT OF 2-DIETHYLAMINOPROPIOPHENONE].
Topics: Abnormalities, Drug-Induced; Animals; Diethylpropion; Female; Humans; Mice; Pregnancy; Rats; Research; Teratogenesis; Thalidomide; Toxicology; Trypan Blue; Vitamin A | 1964 |
THE MECHANISM OF VITAMIN A INDUCED TERATOGENESIS.
Topics: Abnormalities, Drug-Induced; Adrenal Glands; Animals; Cleft Palate; Female; Humans; Male; Maternal-Fetal Exchange; Methylthiouracil; Mice; Pharmacology; Pregnancy; Research; Teratogenesis; Testis; Thyroid Gland; Toxicology; Viscera; Vitamin A | 1964 |
[VITAMIN A AND TERATOGENESIS].
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Female; Humans; Pathology; Pregnancy; Rats; Research; Teratogenesis; Toxicology; Vitamin A; Vitamin A Deficiency | 1964 |
TERATOGENICALLY INDUCED CONGENITAL APHAKIA.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Aphakia; Cataract; Lens, Crystalline; Mice; Pharmacology; Pregnancy; Pregnancy, Animal; Research; Toxicology; Vitamin A | 1964 |
MALFORMATIONS OF THE MOUSE FETUS CAUSED BY HYPERVITAMINOSIS-A OF THE MOTHER DURING PREGNANCY.
Topics: Abnormalities, Drug-Induced; Animals; Fetal Death; Fetus; Hypervitaminosis A; Mice; Mothers; Pharmacology; Pregnancy; Pregnancy, Animal; Research; Statistics as Topic; Toxicology; Vitamin A | 1965 |
CONGENITAL MALFORMATIONS OF UPPER INCISORS IN EXENCEPHALIC MOUSE EMBRYOS, INDUCED BY HYPERVITAMINOSIS A. I. TYPES AND FREQUENCY.
Topics: Abnormalities, Drug-Induced; Animals; Brain Diseases; Embryo, Mammalian; Embryo, Nonmammalian; Hypervitaminosis A; Incisor; Mice; Pharmacology; Research; Tooth Abnormalities; Toxicology; Vitamin A | 1965 |
SOMITE NECROSIS AND DEVELOPMENTAL MALFORMATIONS INDUCED BY VITAMIN A IN THE GOLDEN HAMSTER.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Female; Humans; Mesocricetus; Mesoderm; Necrosis; Pathology; Pregnancy; Pregnancy, Animal; Research; Somites; Toxicology; Vitamin A | 1965 |
[HYPERVITAMINOSIS A AND CONGENITAL MALFORMATIONS IN RAT FETUSES].
Topics: Abnormalities, Drug-Induced; Cleft Palate; Fetus; Hypervitaminosis A; Rats; Research; Spinal Dysraphism; Toxicology; Vitamin A | 1965 |
Teratogenic effects of chronic ingestion of high levels of vitamin A in cats.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Cats; Dose-Response Relationship, Drug; Female; Fertility; Pregnancy; Pregnancy Rate; Prenatal Exposure Delayed Effects; Random Allocation; Retinoids; Specific Pathogen-Free Organisms; Teratogens; Vitamin A | 2003 |
Oxidative stress in liver and brain of the hatchling chicken (Gallus domesticus) following in ovo injection with TCDD.
Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; Brain; Chick Embryo; Chickens; DNA Damage; Drug Antagonism; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Oxidative Stress; Piperonyl Butoxide; Polychlorinated Dibenzodioxins; Teratogens; Vitamin A; Vitamin E | 2003 |
Effect of valproic acid on fetal and maternal organs in the mouse: a morphological study.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Female; Fetus; Gestational Age; Growth Substances; Kidney; Liver; Lung; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Neural Tube Defects; Organ Specificity; Placenta; Pregnancy; Spinal Dysraphism; Teratogens; Valproic Acid; Vitamin A | 2004 |
Potentiation of the teratogenic effects induced by coadministration of retinoic acid or phytanic acid/phytol with synthetic retinoid receptor ligands.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Benzoates; Bexarotene; Dose-Response Relationship, Drug; Drug Synergism; Female; Gestational Age; Ligands; Mice; Mice, Inbred Strains; Phytanic Acid; Phytol; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Teratogens; Tetrahydronaphthalenes; Tretinoin; Vitamin A | 2004 |
Hypervitaminosis A resulting in DNA aberration in fetal transgenic mice (Muta Mouse).
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; DNA Damage; Female; Fetal Resorption; Fetus; Hypervitaminosis A; Mice; Mice, Transgenic; Pregnancy; Vitamin A | 2005 |
Retinoid receptor antagonists alter the pattern of apoptosis in organogenesis stage mouse limbs.
Topics: Abnormalities, Drug-Induced; Animals; Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; Fetal Development; Limb Buds; Limb Deformities, Congenital; Mice; Organogenesis; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Teratogens; Vitamin A | 2006 |
Intake of high levels of vitamin A and polyunsaturated fatty acids during different developmental periods modifies the expression of morphogenesis genes in European sea bass (Dicentrarchus labrax).
Topics: Abnormalities, Drug-Induced; Alkaline Phosphatase; Amylases; Animals; Bass; Diet; Fatty Acids, Unsaturated; Gene Expression Regulation, Developmental; Larva; Morphogenesis; Reverse Transcriptase Polymerase Chain Reaction; Spine; Trypsin; Vitamin A | 2006 |
Casting a broad network: fishing for mechanisms of retinoid teratogenicity.
Topics: Abnormalities, Drug-Induced; Animals; Diterpenes; Dose-Response Relationship, Drug; Gene Expression Profiling; Morphogenesis; Organogenesis; Retinyl Esters; Valproic Acid; Vitamin A | 2006 |
Embryonic essential myosin light chain regulates fetal lung development in rats.
Topics: Abnormalities, Drug-Induced; Animals; Cardiac Myosins; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Infant, Newborn; Lung; Muscle, Smooth; Myosin Light Chains; Phenyl Ethers; Pregnancy; Proteomics; Rats; Rats, Sprague-Dawley; Tissue Culture Techniques; Vitamin A | 2007 |
[Hypervitaminosis A in pregnant female mice of strain C3HA and anomalies of the development of the palate and jaws in their progeny].
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Jaw; Jaw Abnormalities; Mice; Palate; Pregnancy; Time Factors; Vitamin A | 1966 |
The effect of teratogens upon the serum proteins of rats.
Topics: Abnormalities, Drug-Induced; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Blood Proteins; Cortisone; Electrophoresis; Female; Fetal Death; Pregnancy; Pregnancy, Animal; Rats; Trypan Blue; Vitamin A; Vitamin A Deficiency | 1967 |
Vitamins and neural-tube defects.
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Neural Tube Defects; Pregnancy; Vitamin A | 1980 |
Effects of vitamin A on endocardial cushion development in the mouse heart.
Topics: Abnormalities, Drug-Induced; Animals; DNA; Female; Fetal Heart; Germ Layers; Heart Defects, Congenital; Mice; Mice, Inbred ICR; Pregnancy; RNA; Vitamin A | 1981 |
Spina bifida and vitamins.
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Rats; Vitamin A | 1983 |
Spina bifida and vitamins.
Topics: Abnormalities, Drug-Induced; Female; Humans; Pregnancy; Pregnancy Complications; Spina Bifida Occulta; Vitamin A | 1983 |
Vitamin A teratogenicity.
Topics: Abnormalities, Drug-Induced; Female; Humans; Pregnancy; Vitamin A | 1984 |
Vitamin A and the control of development.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Feathers; Limb Deformities, Congenital; Morphogenesis; Regeneration; Tretinoin; Vitamin A; Wings, Animal | 1984 |
Vitamin A: a newly recognized human teratogen. Harbinger of things to come?
Topics: Abnormalities, Drug-Induced; Female; Humans; Pregnancy; Risk; Vitamin A | 1984 |
Dose-response relationships of retinol in production of the Arnold-Chiari malformation.
Topics: Abnormalities, Drug-Induced; Animals; Arnold-Chiari Malformation; Cricetinae; Dose-Response Relationship, Drug; Female; Pregnancy; Vitamin A | 1984 |
Morphometric study of malformations induced by hypervitaminosis A on rat fetus Meckel cartilage, maxillary bone and mandible.
Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Female; Fetus; Histological Techniques; Male; Mandible; Maxilla; Rats; Rats, Inbred Strains; Skull; Vitamin A | 1982 |
A comparison between trisomy 12 and vitamin A induced exencephaly and associated malformations in the mouse embryo.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Chromosomes, Human, 6-12 and X; Ear, Inner; Eye Abnormalities; Female; Humans; Male; Mice; Orbit; Pregnancy; Trisomy; Vitamin A | 1980 |
Malformations of the eye resulting from maternal hypervitaminosis A during gestation in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Eye; Eye Abnormalities; Female; Pregnancy; Rats; Rats, Inbred Strains; Vitamin A | 1981 |
Pathogenesis of limb malformations in mice: an electron microscopic study.
Topics: Abnormalities, Drug-Induced; Animals; Cell Communication; Cell Survival; Ectoderm; Extremities; Female; Fluorouracil; Limb Deformities, Congenital; Mice; Mice, Inbred C57BL; Microscopy, Electron; Pregnancy; Vitamin A | 1983 |
Abnormal development of cultured rat embryos in rat and human sera prepared after vitamin A ingestion.
Topics: Abnormalities, Drug-Induced; Animals; Culture Media; Culture Techniques; Embryo, Mammalian; Female; Fetal Growth Retardation; Head; Humans; Male; Pregnancy; Rats; Vitamin A | 1982 |
General clinical toxicology of oral retinoids.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Adolescent; Adult; Child; Etretinate; Female; Humans; Infant; Isomerism; Isotretinoin; Male; Tretinoin; Vitamin A | 1982 |
Morphogenesis of experimental anencephaly.
Topics: Abnormalities, Drug-Induced; Anencephaly; Animals; Disease Models, Animal; Female; Gestational Age; Male; Morphogenesis; Rats; Vitamin A | 1981 |
Teratology for the dermatologist.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Congenital Abnormalities; Female; Hexachlorophene; Humans; Pregnancy; Skin Diseases; Ultraviolet Therapy; Vitamin A | 1981 |
Teratogenic effects of hypervitaminosis A: an experimental study.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Diseases; Mice; Mice, Inbred Strains; Pregnancy; Pregnancy Complications; Vitamin A | 1980 |
Teratogenicity of high vitamin A intake.
Topics: Abnormalities, Drug-Induced; Dose-Response Relationship, Drug; Facial Bones; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Prevalence; Prospective Studies; Skull; Vitamin A | 1995 |
Vitamin A and birth defects. Continuing caution is needed.
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Pregnancy; Risk; Vitamin A | 1995 |
Antiepileptic drugs alter endogenous retinoid concentrations: a possible mechanism of teratogenesis of anticonvulsant therapy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Isotretinoin; Male; Oxidation-Reduction; Retinoids; Seizures; Tretinoin; Vitamin A | 1995 |
Xenopus laevis: a model system for the study of embryonic retinoid metabolism. I. Embryonic metabolism of 9-cis- and all-trans-retinals and retinols to their corresponding acid forms.
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Embryo, Nonmammalian; Female; Phenotype; Retinaldehyde; Stereoisomerism; Teratogens; Vitamin A; Xenopus laevis | 1995 |
Xenopus laevis: a model system for the study of embryonic retinoid metabolism. II. Embryonic metabolism of all-trans-3,4-didehydroretinol to all-trans-3,4-didehydroretinoic acid.
Topics: Abnormalities, Drug-Induced; Animals; Chromatography, High Pressure Liquid; Embryo, Nonmammalian; Female; Phenotype; Teratogens; Tretinoin; Vitamin A; Xenopus laevis | 1995 |
v-erbA and citral reduce the teratogenic effects of all-trans retinoic acid and retinol, respectively, in Xenopus embryogenesis.
Topics: Abnormalities, Drug-Induced; Acyclic Monoterpenes; Animals; Blotting, Western; Gastrula; Gene Expression; In Situ Hybridization; Microinjections; Monoterpenes; Morphogenesis; Oncogene Proteins v-erbB; Retroviridae Proteins, Oncogenic; RNA, Messenger; Terpenes; Tretinoin; Vitamin A; Xenopus | 1993 |
[Malformations induced by vitamin A administered in the young chick blastoderm].
Topics: Abnormalities, Drug-Induced; Animals; Blastoderm; Chick Embryo; Neural Tube Defects; Vitamin A | 1994 |
Developmental effects of combined exposure to ethanol and vitamin A.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Diet; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Female; Fetus; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Reproduction; Ribs; Tongue; Vitamin A; Weight Gain | 1994 |
The potential for teratogenicity of vitamin A and its congeners.
Topics: Abnormalities, Drug-Induced; Australia; Drug and Narcotic Control; Female; Humans; Infant, Newborn; Pregnancy; Retinoids; Vitamin A | 1993 |
Vitamin A and birth defects.
Topics: Abnormalities, Drug-Induced; Antioxidants; beta Carotene; Carotenoids; Female; Humans; Nutritional Requirements; Pregnancy; Publishing; Vitamin A | 1996 |
Vitamin A and birth defects.
Topics: Abnormalities, Drug-Induced; Female; Humans; Male; Pregnancy; Risk; Vitamin A | 1996 |
Teratogenicity of high vitamin A intake.
Topics: Abnormalities, Drug-Induced; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Pregnancy; Vitamin A | 1996 |
Teratogenicity of high vitamin A intake.
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Pregnancy; Vitamin A | 1996 |
Teratogenicity of high vitamin A intake.
Topics: Abnormalities, Drug-Induced; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Neural Tube Defects; Pregnancy; Skull; Vitamin A | 1996 |
Teratogenicity of high vitamin A intake.
Topics: Abnormalities, Drug-Induced; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Pregnancy; Vitamin A; Vitamin A Deficiency | 1996 |
Teratogenicity of high vitamin A intake.
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Pregnancy; Vitamin A | 1996 |
Long-term administration of high dose vitamin A to rats does not cause fetal malformations: macroscopic, skeletal and physicochemical findings.
Topics: Abnormalities, Drug-Induced; Animals; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Diterpenes; Esters; Female; Maternal-Fetal Exchange; Pregnancy; Rats; Retinyl Esters; Vitamin A | 1996 |
High maternal vitamin A intake and risk of anomalies of structures with a cranial neural crest cell contribution.
Topics: Abnormalities, Drug-Induced; Cleft Lip; Cleft Palate; Facial Bones; Female; Humans; Infant, Newborn; Neural Crest; Pregnancy; Risk Factors; Skull; Vitamin A | 1996 |
Evaluation of the effect of the use of vitamin supplements on vitamin A intake among (potentially) pregnant women in relation to the consumption of liver and liver products.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Evaluation Studies as Topic; Female; Humans; Liver; Middle Aged; Nutritional Status; Pregnancy; Vitamin A; Vitamins | 1996 |
Vitamin A teratogenicity reassessed women warned to watch intake.
Topics: Abnormalities, Drug-Induced; beta Carotene; Carotenoids; Female; Humans; Neural Crest; Pregnancy; Vitamin A | 1996 |
Clinical teratology counseling and consultation report: high dose beta-carotene use during early pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; beta Carotene; Counseling; Female; Humans; Infant, Newborn; Male; Porphyrias; Pregnancy; Pregnancy Outcome; Retinoids; Teratogens; Vitamin A | 1996 |
Demonstration of congenital anomalies in the joints of the forelimbs and hindlimbs caused by several pharmacological agents.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Caffeine; Central Nervous System Stimulants; Cytarabine; Diterpenes; Dose-Response Relationship, Drug; Female; Forelimb; Hindlimb; Joints; Male; Mice; Mice, Inbred BALB C; Pregnancy; Prenatal Exposure Delayed Effects; Retinyl Esters; Sodium Salicylate; Vitamin A | 1996 |
Regeneration of lower and upper jaws in urodeles is differentially affected by retinoic acid.
Topics: Abnormalities, Drug-Induced; Animals; Diterpenes; Gene Expression; In Situ Hybridization; Jaw; Mandible; Maxilla; Notophthalmus; Receptors, Retinoic Acid; Regeneration; Retinyl Esters; Teratogens; Tretinoin; Vitamin A | 1996 |
Vitamin A, birth defects and multivitamin preparations.
Topics: Abnormalities, Drug-Induced; Adult; Drug Labeling; Female; Gestational Age; Humans; Infant, Newborn; Pregnancy; Vitamin A | 1997 |
Retinoids and teratogenicity.
Topics: Abnormalities, Drug-Induced; Case-Control Studies; Dose-Response Relationship, Drug; Female; Humans; Keratolytic Agents; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Retinoids; Tretinoin; Vitamin A | 1998 |
Prevention of congenital abnormalities by vitamin A.
Topics: Abnormalities, Drug-Induced; Case-Control Studies; Congenital Abnormalities; Dose-Response Relationship, Drug; Female; Gestational Age; Humans; Hungary; Infant, Newborn; Pregnancy; Pregnancy Trimester, First; Vitamin A | 1998 |
Ocular abnormalities in Alagille syndrome.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adolescent; Alagille Syndrome; Child; Child, Preschool; Cholesterol; Cornea; Eye Abnormalities; Female; Fluorescein Angiography; Fundus Oculi; Humans; Infant; Iris; Male; Retina; Vitamin A; Vitamin E | 1999 |
Retinoic acid acts during peri-implantational development to alter axial and brain formation.
Topics: Abnormalities, Drug-Induced; Animals; Antineoplastic Agents; Brain; Branchial Region; Embryo Implantation; Female; Limb Deformities, Congenital; Mice; Mice, Inbred Strains; Neural Tube Defects; Receptors, Retinoic Acid; RNA, Messenger; Teratogens; Thorax; Tretinoin; Vitamin A | 1999 |
Teratogenicity, tissue distribution, and metabolism of the retro-retinoids, 14-hydroxy-4,14-retro-retinol and anhydroretinol, in the C57BL/6J mouse.
Topics: Abnormalities, Drug-Induced; Animals; Binding, Competitive; Diterpenes; Dose-Response Relationship, Drug; Eye Abnormalities; Female; Injections, Intraperitoneal; Liver; Male; Mice; Mice, Inbred C57BL; Pregnancy; Tissue Distribution; Vitamin A | 2000 |
Effects of concurrent exposure to 3-methylcholanthrene and vitamin A on fetal development in rats.
Topics: Abnormalities, Drug-Induced; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Female; Fetal Resorption; Fetus; Methylcholanthrene; Microsomes, Liver; Pregnancy; Rats; Rats, Wistar; Teratogens; Tretinoin; Vitamin A | 1999 |
Vitamin A mediated limb deformities in the common Indian toad, Bufo melanostictus (Schneider).
Topics: Abnormalities, Drug-Induced; Animals; Bufonidae; Gene Expression Regulation, Developmental; Genes, Homeobox; Limb Deformities, Congenital; Vitamin A | 2000 |
Effects of excess vitamin A on development of cranial neural crest-derived structures: a neonatal and embryologic study.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Branchial Region; Cell Death; Cell Movement; Cranial Nerves; Craniofacial Abnormalities; DNA-Binding Proteins; Embryo, Mammalian; Embryonic and Fetal Development; Female; Flow Cytometry; Heart Defects, Congenital; Homeodomain Proteins; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Neural Crest; Pregnancy; Thymus Gland; Vitamin A | 2000 |
Prevention of vitamin A teratogenesis by phytol or phytanic acid results from reduced metabolism of retinol to the teratogenic metabolite, all-trans-retinoic acid.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Chromatography, High Pressure Liquid; Drug Synergism; Female; Mice; Mice, Inbred Strains; Phytanic Acid; Phytol; Pregnancy; Prenatal Exposure Delayed Effects; Teratogens; Tretinoin; Vitamin A | 2002 |
Alpha-fetoprotein and albumin in experimentally-induced exencephaly in the rat.
Topics: Abnormalities, Drug-Induced; Albumins; alpha-Fetoproteins; Amniotic Fluid; Animals; Brain; Female; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Vitamin A | 1977 |
Light microscopic and ultrastructural observations in advanced stages of induced exencephaly and spinal bifida.
Topics: Abnormalities, Drug-Induced; alpha-Fetoproteins; Amniotic Fluid; Animals; Cell Differentiation; Cerebral Cortex; Female; Fetal Blood; Hemorrhage; Neural Tube Defects; Pregnancy; Rats; Spina Bifida Occulta; Trypan Blue; Vitamin A | 1979 |
Effects of feeding excess vitamin A to pregnant sows.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Heart; Hematopoietic System; Liver; Organ Size; Pregnancy; Swine; Vitamin A | 1979 |
Influence of various levels of hypervitaminosis A and zinc deficiency on teratogenesis and DNA synthesis in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Cell Differentiation; Cleft Palate; DNA; Eye Abnormalities; Female; Lung; Male; Pregnancy; Rats; Tail; Vitamin A; Zinc | 1979 |
The use of in vitro procedures in teratology.
Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Aminopterin; Animals; Azaserine; Bromodeoxyuridine; Culture Media; Culture Techniques; Diazooxonorleucine; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryo, Nonmammalian; Embryology; Extremities; Female; Gestational Age; Limb Deformities, Congenital; Niacinamide; Protein Biosynthesis; Teratogens; Thalidomide; Vitamin A; Vitelline Membrane | 1975 |
The long search for the causes of congenital malformations in mammals.
Topics: Abnormalities, Drug-Induced; Animals; Cattle; Cattle Diseases; Humans; Polybrominated Biphenyls; Rabbits; Rats; Swine; Swine Diseases; Thalidomide; Vitamin A; Vitamin A Deficiency | 1978 |
The role of amniotic fluid on the in-vitro palatal fusion of normal and vitamin A-treated rat foetuses.
Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Animals; Cleft Palate; Culture Media; Female; Organ Culture Techniques; Palate; Pregnancy; Rats; Vitamin A | 1977 |
Teratogenic effects of retinoic acid in pigtail monkeys (Macaca nemestrina). I. General features.
Topics: Abnormalities, Drug-Induced; Animals; Female; Haplorhini; Macaca; Pregnancy; Tretinoin; Vitamin A | 1977 |
[Apropos of iatrogenic eye abnormalities].
Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Drug-Related Side Effects and Adverse Reactions; Eye; Eye Abnormalities; Female; Humans; Hypoglycemic Agents; Infant, Newborn; Mustard Compounds; Pregnancy; Rabbits; Rats; Vitamin A | 1977 |
Effects of maternal administration of endoxan, vitamin A and vitamin B12 on the development of the fetal spinal cord of the albino mouse.
Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Female; Maternal-Fetal Exchange; Mice; Pregnancy; Spinal Cord; Vitamin A; Vitamin B 12 | 1979 |
Teratogenic interaction of hyperthermia and vitamin A.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Cricetinae; Female; Fever; Pregnancy; Teratogens; Vitamin A | 1979 |
Notochordal-basichondrocranium relationships: abnormalities in experimental axial skeletal (dysraphic) disorders.
Topics: Abnormalities, Drug-Induced; Animals; Arsenates; Cartilage; Clofibrate; Cricetinae; Embryo, Mammalian; Encephalocele; Humans; Mesocricetus; Mice; Notochord; Skull; Vitamin A | 1979 |
Comparison of the effects of retinol and retinoic acid on postimplantation rat embryos in vitro.
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Embryonic Development; Female; In Vitro Techniques; Pregnancy; Protein Biosynthesis; Rats; Tretinoin; Vitamin A | 1977 |
"Chemical surgery" as an approach to study morphogenetic events in embryonic mouse limb.
Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Cell Cycle; Cell Survival; Cytarabine; Extremities; Gestational Age; Limb Deformities, Congenital; Mice; Morphogenesis; Tretinoin; Vitamin A | 1977 |
Malformations of the ear induced by hypervitaminosis A in rat foetuses.
Topics: Abnormalities, Drug-Induced; Animals; Ear; Ear, External; Female; Fetus; Rats; Vitamin A | 1977 |
[The changes of the trunk-skeleton in the rat malformation fetuses produced by hypervitaminosis A (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Female; Jaw Abnormalities; Male; Microstomia; Rats; Spine; Thorax; Vitamin A | 1977 |
An interaction between zinc and vitamin A in pregnant and fetal rats.
Topics: Abnormalities, Drug-Induced; Animals; Drug Interactions; Female; Liver; Maternal-Fetal Exchange; Pregnancy; Rats; Reproduction; Vitamin A; Vitamin A Deficiency; Zinc | 1978 |
The effect of retinoic acid on chondrogenesis in the fetal hamster tibia in vivo.
Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Cell Differentiation; Cricetinae; Female; Hindlimb; Intercellular Junctions; Microscopy, Electron; Pregnancy; Tibia; Tretinoin; Vitamin A | 1978 |
Cellular basis of congenital limb deformity induced in mice by vitamin A.
Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Cell Differentiation; Cell Division; Cell Membrane; Cell Movement; Cell Survival; Collagen; Connective Tissue Cells; Cytoplasmic Granules; Extremities; Female; Humans; Humerus; Limb Deformities, Congenital; Maternal-Fetal Exchange; Mice; Pregnancy; Time Factors; Tretinoin; Ulna; Vitamin A | 1977 |
Effect of intraamniotic administration of vitamin A on rat fetuses.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Cleft Palate; Female; Fetal Resorption; Fetus; Injections; Limb Deformities, Congenital; Micrognathism; Pregnancy; Rats; Vitamin A | 1977 |
Digital anomalies in the embryonic mouse limb cultured in the presence of excess vitamin A.
Topics: Abnormalities, Drug-Induced; Animals; Culture Media; Culture Techniques; Female; Forelimb; Gestational Age; Metacarpus; Mice; Pregnancy; Teratogens; Vitamin A | 1977 |
Placental agenesis, embryonal hydraemia, embryolethality and acute hypervitaminosis A in rats.
Topics: Abnormalities, Drug-Induced; Allantois; Animals; Dose-Response Relationship, Drug; Embryo Loss; Embryo, Mammalian; Female; Fetal Death; Microscopy, Electron, Scanning; Placenta Diseases; Pregnancy; Rats; Time Factors; Vitamin A; Vitelline Membrane | 1976 |
Vitamin A and congenital malformations.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Embryo, Mammalian; Female; Maternal-Fetal Exchange; Pregnancy; Rats; Vitamin A | 1976 |
[Hypervitaminosis A in pregnancy and malformations of the urinary tract in the fetus].
Topics: Abnormalities, Drug-Induced; Adult; Female; Fetus; Humans; Pregnancy; Pregnancy Complications; Urinary Tract; Vitamin A | 1975 |
Analysis of limb anomalies induced in vitro by vitamin A (retinol) in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cell Differentiation; Cells, Cultured; Culture Media; Female; Forelimb; Gestational Age; In Vitro Techniques; Metacarpus; Mice; Mice, Inbred ICR; Pregnancy; Skin; Vitamin A | 1975 |
Preliminary toxicological investigations of 3-hydroxy-3-methylglutaric acid (HMG). I: Study of acute toxicity and of teratogenic activity in rats and mice.
Topics: Abnormalities, Drug-Induced; Animals; Drug Evaluation, Preclinical; Embryo Implantation; Female; Fetal Resorption; Fetus; Glutarates; Hydroxy Acids; Hypolipidemic Agents; Lethal Dose 50; Litter Size; Mice; Pregnancy; Rats; Teratogens; Time Factors; Vitamin A | 1975 |
4-Methylpyrazole partially ameliorated the teratogenicity of retinol and reduced the metabolic formation of all-trans-retinoic acid in the mouse.
Topics: Abnormalities, Drug-Induced; Alcohol Dehydrogenase; Animals; Chromatography, High Pressure Liquid; Depression, Chemical; Female; Fomepizole; Male; Mice; Pregnancy; Pyrazoles; Stereoisomerism; Teratogens; Tretinoin; Vitamin A | 1992 |
Developmental toxicity evaluation of inhaled citral in Sprague-Dawley rats.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Acyclic Monoterpenes; Administration, Inhalation; Animals; Body Weight; Female; Fetal Resorption; Monoterpenes; Pregnancy; Random Allocation; Rats; Rats, Inbred Strains; Respiration Disorders; Terpenes; Vitamin A | 1992 |
Cleft anterior segment with maternal hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Cornea; Female; Humans; Infant, Newborn; Iris; Lens, Crystalline; Vitamin A | 1991 |
[Is vitamin A dangerous?].
Topics: Abnormalities, Drug-Induced; Adolescent; Child; Child, Preschool; Humans; Hypervitaminosis A; Infant; Medication Errors; Nutritional Requirements; Vitamin A | 1991 |
Vitamin A and pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Cattle; Feeding Behavior; Female; Humans; Meat; Nutritional Requirements; Pregnancy; Vitamin A | 1990 |
Biotin deficiency per se is teratogenic in mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Biotin; Cleft Palate; Congenital Abnormalities; Female; Jaw Abnormalities; Limb Deformities, Congenital; Male; Mice; Mice, Inbred ICR; Pregnancy; Pregnancy Complications; Vitamin A | 1991 |
Vitamin A, liver consumption, and risk of birth defects.
Topics: Abnormalities, Drug-Induced; Animals; Cattle; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Liver; Meat; Pregnancy; Risk Factors; Vitamin A | 1990 |
Vitamin A.
Topics: Abnormalities, Drug-Induced; Animal Feed; Female; Humans; Liver; Pregnancy; Vitamin A | 1990 |
Maternal vitamin A supplementation in relation to selected birth defects.
Topics: Abnormalities, Drug-Induced; Canada; Cranial Nerves; Female; Humans; Infant; Isotretinoin; Neural Crest; Pregnancy; Risk Factors; United States; Vitamin A | 1990 |
Epidemiological aspects of prenatal exposure to high doses of vitamin A in Spain.
Topics: Abnormalities, Drug-Induced; Case-Control Studies; Dose-Response Relationship, Drug; Female; Humans; Hypervitaminosis A; Infant, Newborn; Odds Ratio; Pregnancy; Risk Factors; Spain; Time Factors; Vitamin A | 1990 |
Elevations in the endogenous levels of the putative morphogen retinoic acid in embryonic mouse limb-buds associated with limb dysmorphogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Extremities; Female; Kinetics; Limb Deformities, Congenital; Mice; Mice, Inbred ICR; Morphogenesis; Pregnancy; Tretinoin; Vitamin A | 1989 |
Transplacental pharmacokinetics and teratogenicity of a single dose of retinol (vitamin A) during organogenesis in the mouse.
Topics: Abnormalities, Drug-Induced; Animals; Chromatography, High Pressure Liquid; Diterpenes; Dose-Response Relationship, Drug; Female; Fetus; Isomerism; Maternal-Fetal Exchange; Mice; Placenta; Pregnancy; Retinyl Esters; Tissue Distribution; Vitamin A; Yolk Sac | 1989 |
Vitamin A and teratogenesis.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Animals; Female; Humans; Pregnancy; Vitamin A | 1985 |
Teratogenic profile of retinylidene methyl nitrone and retinol in Swiss-Webster mice.
Topics: Abnormalities, Drug-Induced; Animals; Female; Litter Size; Male; Mice; Mice, Inbred Strains; Organ Size; Pregnancy; Retinoids; Teratogens; Vitamin A | 1985 |
Megadose vitamin A and teratogenicity.
Topics: Abnormalities, Drug-Induced; Dose-Response Relationship, Drug; Epidemiologic Methods; Female; Humans; Infant, Newborn; Pregnancy; Spain; Vitamin A | 1988 |
Use of supplements containing high-dose vitamin A--New York State, 1983-1984.
Topics: Abnormalities, Drug-Induced; Female; Humans; New York; Pregnancy; Risk; Vitamin A | 1987 |
Postimplantation embryo culture for the assessment of the teratogenic potential and potency of compounds.
Topics: Abnormalities, Drug-Induced; Animal Testing Alternatives; Animals; Antineoplastic Agents; Culture Techniques; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Embryo, Mammalian; Rats; Vitamin A | 1988 |
Derivation of retinoic acid and metabolites from a teratogenic dose of retinol (vitamin A) in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred ICR; Pregnancy; Tretinoin; Vitamin A | 1988 |
Dangers of large doses of vitamin A during pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Female; Humans; Hypervitaminosis A; Mice; Pregnancy; Pregnancy Complications; Vitamin A | 1988 |
Vitamin A and teratogenesis: recommendations for pregnancy.
Topics: Abnormalities, Drug-Induced; Female; Humans; Pregnancy; Vitamin A | 1988 |
The effects of in vivo administration of teratogenic doses of vitamin A during the preimplantation period in the mouse.
Topics: Abnormalities, Drug-Induced; Animals; Blastocyst; Diterpenes; Female; Fetal Resorption; Litter Size; Mice; Mice, Inbred C3H; Pregnancy; Retinyl Esters; Teratogens; Vitamin A | 1988 |
[Recommendations for the administration of vitamin A in pregnancy].
Topics: Abnormalities, Drug-Induced; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Pregnancy; Risk Factors; Vitamin A | 1988 |
Teratogen update: vitamin A congeners.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Etretinate; Female; Gestational Age; Humans; Infant, Newborn; Isotretinoin; Maternal-Fetal Exchange; Pregnancy; Species Specificity; Teratogens; Tretinoin; Vitamin A | 1986 |
Multiple congenital anomalies associated with apparently normal maternal intake of vitamin A: a phenocopy of the isotretinoin syndrome?
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Diagnosis, Differential; Female; Humans; Infant, Newborn; Isotretinoin; Phenotype; Pregnancy; Tretinoin; Vitamin A; Vitamins | 1987 |
Stage specific response of the mesenchyme to excess vitamin A in developing rat facial processes.
Topics: Abnormalities, Drug-Induced; Animals; DNA Replication; Embryo, Mammalian; Face; Microscopy, Electron, Scanning; Organ Culture Techniques; Rats; Vitamin A | 1986 |
The phenotypic interdependence of the musculoskeletal characters of the mandibular arch in mice.
Topics: Abnormalities, Drug-Induced; Animals; Diterpenes; Ear Ossicles; Genetic Linkage; Mandible; Mice; Musculoskeletal System; Phenotype; Retinyl Esters; Temporomandibular Joint; Vitamin A; Zygoma | 1986 |
Vitamins acting as hormones during craniofacial morphogenesis?
Topics: Abnormalities, Drug-Induced; Animals; Facial Bones; Female; Humans; Mice; Skull; Vitamin A | 1986 |
Carotenoids, vitamin A and cancer.
Topics: Abnormalities, Drug-Induced; Animals; beta Carotene; Carotenoids; Cattle; Diet; Female; Fruit; Humans; Milk; Neoplasms; Pregnancy; Retinoids; Risk; Vegetables; Vitamin A | 1986 |
Megadoses of vitamin A.
Topics: Abnormalities, Drug-Induced; Animals; Humans; Vitamin A | 1986 |
Joint study on the teratogenic sensitivity of the Pika (Ochotona rufescens rufescens) to selected drugs.
Topics: 6-Aminonicotinamide; Abnormalities, Drug-Induced; Animals; Body Weight; Cyclophosphamide; Drug-Related Side Effects and Adverse Reactions; Female; Lagomorpha; Male; Mammals; Mutagenicity Tests; Pregnancy; Pregnancy, Animal; Ribonucleosides; Vitamin A | 1986 |
Leads from the MMWR. Use of supplements containing high-dose vitamin A--New York State, 1983-1984.
Topics: Abnormalities, Drug-Induced; Female; Humans; New York; Pregnancy; Risk; Vitamin A | 1987 |
The mouse as a model in human cleft palate studies.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Humans; Infant, Newborn; Mice; Palate; Palmitates; Pregnancy; Vitamin A | 1985 |
Prevention of neural tube defects in a mouse model and in man.
Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Folic Acid; Gestational Age; Humans; Mice; Neural Tube Defects; Pregnancy; Vitamin A | 1985 |
Letter: Vitamin A and rat embryos.
Topics: Abnormalities, Drug-Induced; Animals; Cell Differentiation; Culture Techniques; Embryo, Mammalian; Female; Liver; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Rats; Vitamin A | 1974 |
The ultrastructural effects of excess maternal vitamin A on the primitive streak stage rat embryo.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Cell Membrane; Central Nervous System; Cleft Palate; Ear; Embryo, Mammalian; Extracellular Space; Eye Abnormalities; Female; Fetal Death; Forelimb; Germ Layers; Microscopy, Electron; Mitochondrial Swelling; Morphogenesis; Pregnancy; Rats; Vitamin A | 1973 |
[Comparison between palatine fissures induced by hypervitaminosis A and Lathyrus odoratus].
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Lathyrism; Pregnancy; Time Factors; Vitamin A | 1969 |
[Congenital maxillo-facial lesions induced by different doses of vitamin A].
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Pregnancy; Pregnancy, Animal; Rats; Vitamin A | 1969 |
The role of sulfated mucopolysaccharides in cleft palate production.
Topics: Abnormalities, Drug-Induced; Acetates; Animals; Autoradiography; Cleft Palate; Cortisone; Drug Synergism; Female; Glycosaminoglycans; Histocytochemistry; Injections, Intraperitoneal; Intubation, Gastrointestinal; Male; Palmitic Acids; Pregnancy; Rats; Sodium; Sulfates; Sulfur Isotopes; Vitamin A | 1970 |
Problems connected with in vivo labelling of embryonic glycosaminoglycans with Na 2 35 SO 4 in teratological studies.
Topics: Abnormalities, Drug-Induced; Animals; Blood; Blood Chemical Analysis; Chemistry Techniques, Analytical; Chromatography; Embryo, Mammalian; Female; Glycosaminoglycans; Isotope Labeling; Pregnancy; Radiometry; Rats; Sodium; Sodium Salicylate; Sulfates; Sulfur Isotopes; Vitamin A | 1971 |
Production of cleft palate with dexamethasone and hypervitaminosis A in rat embryos.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cortisone; Dexamethasone; Embryo, Mammalian; Female; Forelimb; Hindlimb; Micrognathism; Mouth Abnormalities; Pregnancy; Rats; Syndactyly; Vitamin A | 1970 |
Lack of hypertrophy of the adrenal in exencephalic fetal rats subjected to hypervitaminosis A and then to maternal adrenalectomy.
Topics: Abnormalities, Drug-Induced; Adrenal Glands; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Body Weight; Brain; Female; Fetal Diseases; Hypertrophy; Maternal-Fetal Exchange; Organ Size; Pituitary Gland; Pituitary-Adrenal System; Pregnancy; Rats; Vitamin A | 1971 |
Hypervitaminosis A dysmelia in rats.
Topics: Abnormalities, Drug-Induced; Animals; Bone Development; Carpal Bones; Female; Forelimb; Hindlimb; Male; Pregnancy; Rats; Syndactyly; Tarsal Bones; Vitamin A | 1971 |
The comparative pathogenesis of experimentally induced cleft palate.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Hydroxyzine; Maxillofacial Development; Piperazines; Pregnancy; Pregnancy, Animal; Rats; Tranquilizing Agents; Vitamin A | 1966 |
Prolonged gestation in the rat and its usefulness in experimental teratology.
Topics: Abnormalities, Drug-Induced; Animals; Cryptorchidism; Edema; Embryonic and Fetal Development; Face; Female; Fetus; Jaw Abnormalities; Limb Deformities, Congenital; Male; Nitriles; Piperazines; Pregnancy; Pregnancy, Prolonged; Progesterone; Prognathism; Rats; Spine; Vitamin A | 1969 |
Letter: Vitamin A, pregnancy, and oral contraceptives.
Topics: Abnormalities, Drug-Induced; Contraceptives, Oral; Female; Humans; Pregnancy; Time Factors; Vitamin A | 1974 |
Lathyrogenic effects of vitamin A in the rat embryo.
Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Cleft Palate; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Jaw Abnormalities; Lathyrism; Macroglossia; Mandible; Maxilla; Nasal Septum; Palate; Pregnancy; Rats; Vitamin A | 1974 |
Susceptible stages and abnormal morphogenesis in the developing mouse limb, analysed in organ culture after transplacental exposure to vitamin A (retinoic acid).
Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Ectromelia; Extremities; Female; Limb Deformities, Congenital; Maternal-Fetal Exchange; Mice; Mice, Inbred DBA; Morphogenesis; Organ Culture Techniques; Pregnancy; Teratogens; Time Factors; Vitamin A | 1974 |
[Overdosing with vitamin a].
Topics: Abnormalities, Drug-Induced; Adult; Animals; Child; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Pregnancy; Vitamin A | 1974 |
The effect of excess vitamin A on the development of rat embryos in culture.
Topics: Abnormalities, Drug-Induced; Animals; Cell Differentiation; Culture Techniques; DNA; Embryo, Mammalian; Female; Maternal-Fetal Exchange; Microscopy, Electron; Pregnancy; Rats; Vitamin A | 1974 |
The effects of vitamin A and tetracycline on a mouse tooth anomaly.
Topics: Abnormalities, Drug-Induced; Animals; Biometry; Female; Mice; Molar; Odontogenesis; Pregnancy; Tetracycline; Tooth; Tooth Abnormalities; Vitamin A | 1973 |
Effect of vitamin A on the potentiality of rat palatal processes to fuse in vivo and in vitro.
Topics: Abnormalities, Drug-Induced; Animals; Bone Development; Cleft Palate; Culture Techniques; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Methods; Palate; Pregnancy; Rats; Vitamin A | 1974 |
Gross congenital malformations. Animal model: treatment of various species with a large dose of vitamin A at known stages in pregnancy.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anencephaly; Animals; Anus, Imperforate; Cleft Lip; Cleft Palate; Cricetinae; Disease Models, Animal; Ectromelia; Female; Fetus; Heart Septal Defects, Ventricular; Hernia, Ventral; Hydronephrosis; Micrognathism; Microphthalmos; Morphogenesis; Pregnancy; Spinal Dysraphism; Vitamin A | 1972 |
The effects of various levels of dietary protein on retinoic acid-induced teratogenicity in rats.
Topics: Abnormalities, Drug-Induced; Animals; Blood Proteins; Blood Urea Nitrogen; Dietary Proteins; Female; Lipid Metabolism; Liver; Ossification, Heterotopic; Pregnancy; Pregnancy Complications; Protein Deficiency; Rats; Vitamin A | 1972 |
The marmoset as a model for teratological research.
Topics: Abnormalities, Drug-Induced; Animals; Estrus; Female; Haplorhini; Pregnancy; Thalidomide; Twins; Vitamin A | 1972 |
Delayed hatching time of chicks from dams fed excess vitamin A and from eggs injected with vitamin A.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Chickens; Diet; Eggs; Female; Liver; Palmitic Acids; Poultry Diseases; Time Factors; Vitamin A | 1972 |
Morphogenesis of the malformations induced in rat embryos by maternal hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Animals; Ectoderm; Embryo, Mammalian; Endoderm; Female; Fetus; Mesoderm; Morphogenesis; Pregnancy; Rats; Vitamin A | 1972 |
A learning impairment associated with maternal hypervitaminosis-A in rats.
Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Body Weight; Central Nervous System; Female; Fetal Death; Fetal Diseases; Gestational Age; Humans; Learning Disabilities; Male; Pregnancy; Rats; Time Factors; Vitamin A | 1972 |
Skullbase malformations in rat fetuses with hypervitaminosis A-induced exencephaly.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetus; Rats; Skull; Vitamin A | 1973 |
Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Cleft Palate; Ectromelia; Embryo, Mammalian; Exophthalmos; Forelimb; Genitalia; Hindlimb; Jaw Abnormalities; Mice; Mice, Inbred DBA; Microcephaly; Mouth Abnormalities; Ribs; Spine; Sternum; Tail; Vitamin A | 1973 |
Absent and abnormal umbilical arteries.
Topics: Abnormalities, Drug-Induced; Animals; Arteriovenous Anastomosis; Female; Maternal-Fetal Exchange; Placenta; Pregnancy; Rats; Umbilical Arteries; Vitamin A | 1973 |
Vitamin A-induced anomalies in young rat embryos.
Topics: Abnormalities, Drug-Induced; Animals; Decidua; Female; Fetus; Placenta; Rats; Vitamin A | 1973 |
Maternal vitamin A excess during the early fetal period: effects on learning and development in the offspring.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Brain; Conditioning, Operant; Discrimination Learning; Disease Models, Animal; Electroshock; Female; Fetus; Gestational Age; Growth; Humans; Inhibition, Psychological; Male; Maternal-Fetal Exchange; Organ Size; Pregnancy; Punishment; Rats; Vitamin A | 1973 |
The morphology of various types of cell death in prenatal tissues.
Topics: Abnormalities, Drug-Induced; Animals; Cell Survival; Cyclophosphamide; Dactinomycin; Embryo, Mammalian; Embryonic and Fetal Development; Female; Fetus; Magnesium Deficiency; Mercaptopurine; Mice; Mice, Inbred Strains; Microscopy, Electron; Necrosis; Niacinamide; Pregnancy; Rats; Rats, Inbred Strains; Vincristine; Vitamin A | 1973 |
Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Ectromelia; Female; Forelimb; Hindlimb; Limb Deformities, Congenital; Mice; Mice, Inbred DBA; Pregnancy; Teratogens; Time Factors; Tretinoin; Vitamin A | 1973 |
Editorial: Hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Adult; Animals; Child; Female; Humans; Hypercalcemia; Intracranial Pressure; Male; Mental Disorders; Nutritional Requirements; Pregnancy; Rats; United States; United States Food and Drug Administration; Vitamin A | 1974 |
Vitamin A, pregnancy, and oral contraceptives.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Contraceptives, Oral; Diet; Female; Fetus; Humans; Pregnancy; Time Factors; Vitamin A | 1974 |
Proceedings: A study of the extent to which maternal nutrition after delivery reflects the situation in early pregnancy.
Topics: Abnormalities, Drug-Induced; Carotenoids; Diet; Female; Folic Acid; Humans; Nutrition Disorders; Postpartum Period; Pregnancy; Pregnancy Complications; Vitamin A | 1974 |
Hypervitaminosis A and congenital renal anomalies in a human infant.
Topics: Abnormalities, Drug-Induced; Adult; Contrast Media; Female; Humans; Infant; Kidney; Kidney Diseases; Male; Pregnancy; Pregnancy Complications; Radiography; Vitamin A | 1974 |
Letter: Vitamin A and the teratogenic risks of oral contraceptives.
Topics: Abnormalities, Drug-Induced; Contraceptives, Oral; Female; Humans; Infant, Newborn; Pregnancy; Protein Binding; Vitamin A | 1974 |
Teratogenic activity of retinoic acid.
Topics: Abnormalities, Drug-Induced; Animals; Female; Pregnancy; Pregnancy, Animal; Rats; Spinal Dysraphism; Vitamin A | 1967 |
Movement of palatine shelves in untreated and teratogen-treated mouse embryos.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cortisone; Embryo, Mammalian; Female; Histological Techniques; Mice; Palate; Pregnancy; Tongue; Vitamin A | 1967 |
[Problem of embryotoxicity of vitamin A].
Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Male; Pregnancy; Pregnancy, Animal; Rats; Vitamin A | 1971 |
Morphological and autoradiographic studies of cleft palate induced in rat embryos by maternal hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Animals; Autoradiography; Cleft Palate; Embryo, Mammalian; Eye Abnormalities; Palate; Rats; Sulfur Isotopes; Vitamin A | 1965 |
[Apropos of embryotoxic and teratogenic actions of "triton W.R. 1339" in the mouse: influence of vitamin A].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Birth Rate; Drug Antagonism; Drug Synergism; Female; Mice; Pregnancy; Progesterone; Surface-Active Agents; Vitamin A | 1970 |
Experimental formation of goiter in exencephalic fetal rats subjected to maternal hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Brain; Diencephalon; Female; Fetus; Gestational Age; Goiter; Hypophysectomy; Hypothalamus; Maternal-Fetal Exchange; Organ Size; Pituitary Gland; Pregnancy; Propylthiouracil; Rats; Thiourea; Thyroid Gland; Thyrotropin-Releasing Hormone; Vitamin A | 1971 |
[Teratogenic effect of retinol on the chick embryo].
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Injections; Vitamin A | 1971 |
Morphogenesis of malformations in hamsters caused by retinoic acid: relation to dose and stage at treatment.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Embryo, Mammalian; Female; Fetal Death; Fetus; Gestational Age; Lethal Dose 50; Pregnancy; Vitamin A | 1972 |
[Hypervitaminosis A in rat embryos. Autoradiographic studies on the teratogenic effect].
Topics: Abnormalities, Drug-Induced; Animals; Autoradiography; DNA; Embryo, Mammalian; Female; Mesencephalon; Rats; Rats, Inbred Strains; Telencephalon; Thymidine; Tritium; Vitamin A | 1972 |
The localization of vitamin A in the pregnant rat by means of fluorescence microscopy.
Topics: Abnormalities, Drug-Induced; Adrenal Glands; Animals; Embryo, Mammalian; Endometrium; Female; Kidney; Microscopy, Fluorescence; Placenta; Pregnancy; Pregnancy, Animal; Rats; Thyroid Gland; Uterus; Vitamin A | 1972 |
[Hypervitaminosis A. I. Potential teratogenic activities].
Topics: Abnormalities, Drug-Induced; Animals; Esters; Female; Fertilization; Palmitic Acids; Pregnancy; Pregnancy Complications; Rats; Time Factors; Vitamin A; Vitamin E | 1972 |
[The prenatal influence of chloridin and vitamin A on the behavior of the progeny of rats].
Topics: Abnormalities, Drug-Induced; Animals; Behavior, Animal; Central Nervous System Diseases; Female; Humans; Learning Disabilities; Movement Disorders; Pregnancy; Pyrimethamine; Rats; Vitamin A | 1971 |
[Teratogenic action of hypervitaminosis A and hydrocortisone in experimental maternal hypothyroidism].
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Female; Hydrocortisone; Hypothyroidism; Pregnancy; Rats; Vitamin A | 1971 |
Congenitalmalformations of upper incisors in exencephalic mouse embryos, induced by hypervitaminosis A. II. Morphology of fused upper incisors.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Embryo, Mammalian; Incisor; Mice; Tooth Abnormalities; Tooth Germ; Vitamin A | 1965 |
[Malformations of upper incisors in exencephalic mouse embryos, induced by hypervitaminosis A].
Topics: Abnormalities, Drug-Induced; Animals; Brain Damage, Chronic; Incisor; Mice; Tooth Abnormalities; Vitamin A | 1967 |
The infraseptal nasal glands in mouse embryos with dental malformations and exencephaly induced by hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Embryo, Mammalian; Incisor; Mice; Nose; Tooth Abnormalities; Vitamin A | 1967 |
Dental malformations in rat embryos with exencephaly induced by hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Embryo, Mammalian; Jaw Abnormalities; Rats; Tooth Abnormalities; Vitamin A | 1967 |
[On the etiopathogenesis of special jaw and dental dysplasias].
Topics: Abnormalities, Drug-Induced; Animals; Mandible; Mice; Tongue; Vitamin A | 1968 |
[Effect of various drugs on the abnormality induced by excessive intake of vitamin A. 1. Effect of cortisone].
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cortisone; Drug Synergism; Female; Pregnancy; Rats; Vitamin A | 1967 |
Tooth germs in non-exencephalic siblings of mouse embryos with exencephaly induced by hyper-vitaminosis A.
Topics: Abnormalities, Drug-Induced; Animals; Brain; Female; Mice; Odontogenesis; Pregnancy; Pregnancy, Animal; Tooth Abnormalities; Tooth Germ; Vitamin A | 1967 |
Dental anomalies in mouse embryos with hydrocephalus induced by hypervitaminosis.
Topics: Abnormalities, Drug-Induced; Animals; Anodontia; Female; Hydrocephalus; Jaw Abnormalities; Masticatory Muscles; Mice; Mouth Abnormalities; Pregnancy; Pregnancy, Animal; Tooth Germ; Vitamin A | 1967 |
Tritiated thymidine labelling of the palatal processes of rat embryos with cleft palate induced by hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Autoradiography; Cell Nucleus; Cleft Palate; DNA; Embryo, Mammalian; Female; Injections; Mitosis; Palate; Pregnancy; Rats; Thymidine; Tritium; Vitamin A | 1971 |
[Teratogenic effects of vitamin A. 2. Chemical structure of vitamin A].
Topics: Abnormalities, Drug-Induced; Animals; Anus, Imperforate; Chemical Phenomena; Chemistry; Rats; Rats, Inbred Strains; Sternum; Tail; Vitamin A | 1971 |
[Vitamin therapy and fetal abnormalities].
Topics: Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Pregnancy; Vitamin A; Vitamin D | 1971 |
The rapid detection of teratogenic activity.
Topics: Abnormalities, Drug-Induced; Animals; Bromodeoxyuridine; Colchicine; Craniofacial Dysostosis; Cricetinae; Dwarfism; Female; Heart Defects, Congenital; Microcephaly; Pregnancy; Pregnancy, Animal; Spinal Dysraphism; Trypan Blue; Vitamin A | 1965 |
[Telencephalic commissures in the cyclocephalic mouse fetus].
Topics: Abnormalities, Drug-Induced; Abnormalities, Severe Teratoid; Animals; Diencephalon; Female; Male; Mesencephalon; Mice; Pregnancy; Radiation Injuries, Experimental; Telencephalon; Vitamin A | 1966 |
Potentiation of the teratogenic effect of vitamin A with exposure to low environmental temperature.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animals; Brain; Cold Temperature; Cricetinae; Embryo, Mammalian; Female; Hernia, Ventral; Pregnancy; Pregnancy, Animal; Spinal Dysraphism; Vitamin A | 1967 |
Lysosomes and congenital malformations.
Topics: Abnormalities, Drug-Induced; Animals; Azo Compounds; Cortisone; Female; Lysosomes; Pregnancy; Rats; Suramin; Surface-Active Agents; Thiomalates; Trypan Blue; Vitamin A | 1969 |
Teratogenic effects of hypervitaminosis A in the hamster and the guinea pig.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Female; Fetal Death; Fetus; Gestational Age; Guinea Pigs; Head; Heart Defects, Congenital; Pregnancy; Urogenital Abnormalities; Vitamin A | 1970 |
[Range of teratogenic action as an indication of danger in using a medicinal preparation during pregnancy].
Topics: Abnormalities, Drug-Induced; Animals; Busulfan; Female; Pregnancy; Pregnancy Complications; Pyrimethamine; Rats; Vitamin A | 1970 |
Effects of oral contraceptives on human plasma vitamin-A levels.
Topics: Abnormalities, Drug-Induced; Adult; Carotenoids; Contraceptives, Oral; Female; Humans; Menstruation; Pregnancy; Vitamin A | 1971 |
[Case of Pierre-Robin syndrome considered as an embryoblastosis and development of experimental micrognathia].
Topics: Abnormalities, Drug-Induced; Animals; Cyclophosphamide; Female; Humans; Infant; Maternal-Fetal Exchange; Mice; Micrognathism; Pierre Robin Syndrome; Pregnancy; Vitamin A | 1967 |
Embryonic uptake of S35-sulfate: change in level following treatment with some teratogenic agents.
Topics: Abnormalities, Drug-Induced; Animals; Cortisone; Embryo, Mammalian; Female; Mice; Pregnancy; Sulfates; Sulfur Isotopes; Trypan Blue; Vitamin A | 1968 |
Skeletal abnormalities in the hindlimbs of young cats as a result of hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Cats; Femur; Hindlimb; Tibia; Vitamin A | 1968 |
Changes of endocrine glands produced by teratogenic methods. The pituitary gland.
Topics: Abnormalities, Drug-Induced; Adrenal Glands; Anencephaly; Animals; Female; Hydrocephalus; Pituitary Gland; Pregnancy; Pregnancy, Animal; Radiation Genetics; Rats; Salicylates; Streptonigrin; Trypan Blue; Vitamin A | 1968 |
[On some experimental malformations of the tongue and mandible].
Topics: Abnormalities, Drug-Induced; Animals; Fetus; Hyperplasia; Jaw Abnormalities; Mandible; Radiation Effects; Radiation Injuries, Experimental; Rats; Tongue; Tongue, Fissured; Vitamin A | 1968 |
Studies of vitamin A-induced teratogenesis: effects on embryonic mesenchyme and epithelium, and on incorporation of H3-thymidine.
Topics: Abnormalities, Drug-Induced; Animals; Cell Differentiation; Cell Division; Cell Membrane Permeability; Cleft Palate; Embryo, Mammalian; Epithelium; Female; Maxilla; Mesoderm; Mouth Abnormalities; Pregnancy; Rats; Thymidine; Tritium; Vitamin A | 1968 |
Vitamin A as a possible factor in human teratology.
Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Female; Fetus; Humans; Infant, Newborn; Liver; Pregnancy; Vitamin A; Vitamin A Deficiency | 1969 |
Variations in teratogenic response to hypervitaminosis A in three strains of the albino rat.
Topics: Abnormalities, Drug-Induced; Anencephaly; Animals; Anophthalmos; Bone and Bones; Cleft Palate; Female; Hydronephrosis; Meningocele; Pregnancy; Rats; Species Specificity; Vitamin A | 1969 |
[Abnormalities due to defective diet. I. Experiments with mammals and observations in humans].
Topics: Abnormalities, Drug-Induced; Abortion, Criminal; Abortion, Legal; Aminopterin; Animals; Congenital Abnormalities; Deficiency Diseases; Female; Folic Acid; Humans; Hyperemesis Gravidarum; Maternal-Fetal Exchange; Pantothenic Acid; Pregnancy; Pregnancy Complications; Riboflavin; Socioeconomic Factors; Starvation; Swine; Vitamin A | 1969 |
Parallel experiment on teratogenic effects of hypervitaminosis-A upon mice embryos of two strains.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Female; Mice; Pregnancy; Species Specificity; Vitamin A | 1965 |
Absence of teratogenic effect of butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) in rats and mice.
Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; Dietary Fats; Female; Fertility; Mice; Pregnancy; Pregnancy, Animal; Rats; Vitamin A | 1965 |
[Hypervitaminosis A in pregnancy and neonatal malformations of the urinary tract].
Topics: Abnormalities, Drug-Induced; Adult; Female; Humans; Infant, Newborn; Pregnancy; Pregnancy Complications; Urogenital Abnormalities; Vitamin A | 1965 |
Strain differences in malformations of the extremities of the mouse fetus caused by x-radiation, hypoxia or hypervitaminosis-A of the mother during pregnancy.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Female; Fetus; Hypoxia; Limb Deformities, Congenital; Mice; Pregnancy; Radiation Injuries, Experimental; Species Specificity; Vitamin A | 1964 |
Mesodermal alterations induced by hypervitaminosis A.
Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Female; Mesoderm; Pregnancy; Pregnancy, Animal; Vitamin A | 1966 |
[Ppreliminary observations on some malformations induced with vitamin A in embryos of Bufo vulgaris, with special reference to those of the cephalic end. I].
Topics: Abnormalities, Drug-Induced; Animals; Anura; Vitamin A | 1966 |
[Preliminary histological observations on some malformations induced with vitamin A in embryos of Bufo vulgaris, with special reference to those of the cephalic end. II].
Topics: Abnormalities, Drug-Induced; Animals; Anura; Vitamin A | 1966 |