retinol-acetate and Colonic-Neoplasms

retinol-acetate has been researched along with Colonic-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for retinol-acetate and Colonic-Neoplasms

ArticleYear
[Correction of biochemical and immunological indices in colonic cancer using optimal doses of retinyl acetate and ascorbic acid].
    Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 96, Issue:9

    Blood plasma retinol level in normal donors and patients with colonic carcinoma was measured by high-pressure liquid chromatography and the concentration of p-hydroxyphenyl lactic and homogentizine acids by Gas Chromatograph Mass Spectrometer MAT-311A using 2H4-p-hydroxyphenylacetic acid as internal reference. The functional activity of lymphocytes was estimated from the proliferative response to alloantigens in a one-way mixed lymphocyte culture and in blast transformation reaction to Con A and pokeweed mitogen. After systematic intake of retinyl acetate and ascorbic acid in optimally high doses, the patients manifested an increase in vitamin C level in plasma and lymphocytes and a lowering of p-hydroxyphenyl lactic acid excretion. Blood plasma retinol remained unchanged. Daily intake of retinyl acetate and ascorbic acid for 8-12 days produced a significant increase of lymphocyte proliferation in response to alloantigens in mixed lymphocyte culture and blast transformation reaction to suboptimal mitogen doses.

    Topics: Adult; Aged; Ascorbic Acid; Colonic Neoplasms; Diterpenes; Homogentisic Acid; Humans; Lymphocyte Activation; Middle Aged; Phenylpropionates; Retinyl Esters; Vitamin A

1983