resveratrol has been researched along with Fibrosis in 74 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (8.11) | 29.6817 |
| 2010's | 50 (67.57) | 24.3611 |
| 2020's | 18 (24.32) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; He, T; Zhang, J; Zhang, Z | 1 |
| Peng, YF; Sun, L; Wu, XX | 1 |
| Chen, M; Chen, Q; Huang, S; Wu, Y; Yang, X; Zeng, Y; Zhang, S; Zhong, Y | 1 |
| Bi, W; Du, H; Lei, T; Xiao, Z; Yang, Y; Zhang, X | 1 |
| Geng, J; Gu, W; Guan, Y; Hou, X; Li, X; Song, G; Wang, C; Wang, X; Yang, L; Zheng, K | 1 |
| Bai, Y; Cheng, G; Du, B; Jiao, Q; Wang, Y; Yu, L; Zhao, M | 1 |
| Chen, J; Chen, X; Huang, M; Li, F; Li, P; Ma, Y; Wei, R | 1 |
| Bao, L; Chen, X; Fan, X; Li, W; Liu, N; Shao, Y; Wang, H; Ye, J; Zhao, D | 1 |
| Bu, P; Hai, J; Hu, Y; Kong, B; Ma, X; Ti, Y; Yang, Y; Zhang, C; Zhao, Y; Zheng, X | 1 |
| Li, D; Liu, Y; Lv, J; Zhang, R | 1 |
| Chen, L; Chen, Y; Fan, J; Jiang, Y; Sheng, M; Wei, S; Zhang, X | 1 |
| Bai, Y; Guo, Y; Lu, H; Wu, C; Xiao, Y; Xie, S; Zhang, X; Zhang, Y; Zheng, S; Zhu, H | 1 |
| Eldred, JA; Smith, AJO; Wormstone, IM | 1 |
| Chen, C; Fang, J; Guo, SB; Han, X; Li, HH; Li, PB; Lin, QY; Wang, QS; Yan, X; Zhang, YL; Zou, LX | 1 |
| Du, L; He, LL; Li, CC; Li, XZ; Li, Y; Liu, YQ; Lu, Q; Ma, P; Qian, X; Shu, FL; Xu, L; Yin, XX | 1 |
| Abdel-Bakky, MS; Abdelrehim, AB; Bayoumi, AMA; Beshay, ON; Ewees, MG; Hafez, SMNA | 1 |
| Arancio, A; Castiglione, R; Catania, VE; Malaguarnera, M; Sidoti, G; Vicari, BO; Vicari, E | 1 |
| Chang, ZY; Chen, CC; Chen, SY; Tsai, FJ | 1 |
| Chen, W; Chen, Y; Huang, M; Liang, J; Lin, B; Lin, Q; Wu, Q; Xing, Y; Xu, X; Yao, Q | 1 |
| Hallajzadeh, J; Mirsafaei, L; Reiner, Ž; Zivarpour, P | 1 |
| Netticadan, T; Parikh, M; Raj, P; Sayfee, K; Wigle, J; Yu, L; Zieroth, S | 1 |
| Duan, X; Gong, FT; He, Y; Liu, Q; Yang, B; Yu, Y; Zeng, HZ; Zeng, XN; Zhang, JS | 1 |
| He, L; Liu, G; Liu, H; Peng, X; Peng, Y; Shi, Y; Wang, Q | 1 |
| He, Y; Liu, Q; Yang, B; Yu, Y; Zeng, H; Zhang, J | 1 |
| Gong, F; He, Y; Liu, Q; Yang, B; Yu, Y; Zeng, H; Zeng, X; Zhang, J | 1 |
| Liu, K; Tsang, SW; Xia, Y; Xiao, HT; Zhang, HJ | 1 |
| Chang, YS; Choi, BS; Kim, EN; Kim, MY; Kim, Y; Kim, YS; Lim, JH; Park, CW; Shin, SJ; Yoon, HE | 1 |
| Li, Y; Liu, Z; Sheng, L; Yuan, Y; Zhang, S; Zhang, Y; Zhao, X | 1 |
| Ban, TH; Chang, YS; Choi, BS; Jang, IA; Kim, EN; Kim, MY; Lim, JH; Park, CW; Yoon, HE | 1 |
| Aabdelbaset, M; Ammar, HI; Ashour, H; Fadel, M; Kamar, SS; Rashed, LA; ShamsEldeen, AM; Shoukry, HS | 1 |
| Christovam, AC; do Amaral, MEC; Dos Santos, GMT; Esquisatto, MAM; Mendonça, FAS; Theodoro, V | 1 |
| Bresette, W; Chen, Y; Cheng, J; Li, L; Liu, J; Liu, S; Lu, Y; Wang, C; Yuan, Y; Zhao, M; Zhou, Y | 1 |
| Bai, B; Chen, H; Liang, G; Liu, H; Shan, X; Sun, C; Wu, B; Zhang, W; Zhang, Y | 1 |
| Bai, L; Ding, S; Wang, H; Wang, M; Wu, W; Yu, P | 1 |
| Fan, XF; Gong, YS; Han, LP; Li, X; Liu, ZH; Wang, X; Zhang, Y | 1 |
| Han, J; Liang, J; Tian, S; Xiong, P | 1 |
| Chen, J; Guan, Y; Hao, CM; Huang, XZ; Ma, L; Ren, Y; Wen, D; Xie, Q; Zhang, M | 1 |
| Arkell, AM; Beaudoin, MS; Chabowski, A; Holloway, GP; Perry, CG; Simpson, JA; Wright, DC | 1 |
| Doser, TA; Ge, J; Hu, N; Mi, SL; Ren, J; Sun, A; Zhang, Y | 1 |
| Gong, YY; Heng, D; Li, P; Liang, ML; Lin, L; Wang, Y; Zhu, Y | 1 |
| Abd-Elaziz, HR; Arafa, MH; Atteia, HH; Mohammad, NS | 1 |
| Fu, LJ; Huang, Y; Kong, YL; Liu, J; Lu, LM; Ni, J; Shao, DC; Shen, Y; Wang, Z; Xue, H; Yu, C; Zhang, W; Zhou, L | 1 |
| Bai, Y; Chen, B; Liang, Y; Lin, C; Lu, H; Wang, S; Wu, C; Xia, P | 1 |
| Conte, E; Fagone, E; Fruciano, M; Gili, E; Iemmolo, M; Vancheri, C | 1 |
| Bu, P; Chen, T; Li, J; Li, N; Liu, H; Liu, J; Wang, S; Zeng, M; Zhang, Y | 1 |
| Andrade, CB; Barbé-Tuana, F; Borojevic, R; de Oliveira, CM; de Souza, IC; de Vasconcelos, M; Guaragna, R; Guma, FC; Margis, R; Martins, LA; Pettenuzzo, LF | 1 |
| Bian, ZX; Lin, Z; Mu, H; Tsang, SW; Zhang, H | 1 |
| Bi, C; Cai, B; Chen, H; Feng, D; Li, X; Liang, J; Liu, Y; Lu, Y; Ma, W; Wang, Y; Yang, F; Yin, K; Zhao, L | 1 |
| Chen, J; Hai-Yan, Q; Hong, W; Jian-Feng, H; Jue, W; Qian, Z; Shou-Dong, W; Tatsuo, S; Yue-Jin, Y | 1 |
| Chen, C; Meng, T; Xiao, Z; Zhang, W; Zhou, Q | 1 |
| Isseroff, RR; Jagdeo, J; Koo, E; Mamalis, A; Murphy, W | 1 |
| Basu, R; Das, SK; DesAulniers, J; Dyck, JR; Fan, D; Hajjar, RJ; Kassiri, Z; McLean, B; Oudit, GY; Parajuli, N; Patel, VB; Wang, W; Zhabyeyev, P | 1 |
| Berrino, L; Cappetta, D; Ciuffreda, LP; De Angelis, A; Esposito, G; Piegari, E; Rivellino, A; Rossi, F; Russo, R; Urbanek, K | 1 |
| Chen, JZ; Chen, QH; Kang, LN; Li, GN; Li, R; Wei, ZH; Wu, H; Xie, J; Xu, B | 1 |
| Beauloye, C; Bertrand, L; Daskalopoulos, EP; Dufeys, C; Horman, S | 1 |
| Fujita, K; Honda, Y; Imajo, K; Kato, S; Kato, T; Kessoku, T; Mawatari, H; Nagashima, Y; Nakajima, A; Ogawa, Y; Saito, S; Tomeno, W; Wada, K; Yoneda, M | 1 |
| Lu, Y; Wang, D; Zhang, C; Zhou, Y | 1 |
| Huang, F; Kou, J; Li, A; Li, J; Li, X; Liu, B; Liu, K; Qi, LW; Qiu, Z; Wang, L | 1 |
| Cao, YJ; Chen, XL; Fan, YP; Huang, XZ; Xue, HY; Yuan, L | 1 |
| Guan, X; He, T; Huang, Y; Liu, L; Nie, L; Sharma, K; Wang, J; Xiao, T; Xiong, J; Xu, X; Yang, K; Yu, Y; Zhang, D; Zhang, J; Zhao, J | 1 |
| Chen, L; Li, GN; Li, R; Sheng, ZQ; Wang, L; Wu, H; Xie, J; Xu, B | 1 |
| Ahmet, I; Lakatta, EG; Tae, HJ; Talan, M | 1 |
| Choo, HY; Hashem, MA; Jun, KY; Kwon, Y; Lee, E; Lim, S | 1 |
| Hashimoto, T; Ichiki, T; Inanaga, K; Matsuura, H; Miyazaki, R; Sunagawa, K; Takeda, K | 1 |
| Hua, YM; Li, MY; Shi, XQ; Wang, YB; Wang, ZP; Zhang, X | 1 |
| Esrefoglu, M; Kuruş, M; Ugras, M | 1 |
| Breyer, MD; Davis, LS; Fan, H; Fogo, AB; Hao, CM; Harris, RC; He, W; Wang, Y; Yang, HC; You, L; Zent, R; Zhang, MZ | 1 |
| Bertram, JF; Li, J; Nikolic-Paterson, DJ; Qu, X; Ricardo, SD | 1 |
| Brown, L; Chan, V; Fenning, A; Hoey, A; Iyer, A | 1 |
| Hori, YS; Horio, Y; Hosoda, R; Kuno, A; Miura, T; Shimamoto, K; Tanno, M | 1 |
| Adler, J; Christman, GM; Dhanani, M; McKenna, BJ; Rahal, K; Reingold, L; Rittershaus, AC; Schmiedlin-Ren, P; Sultani, V; Zhu, J; Zimmermann, EM | 1 |
| Ahn, YB; Kim, HW; Kim, JW; Ko, SH; Lee, EM; Lee, YE; Li, G; Liu, Z; Park, CW; Song, KH; Yoon, KH | 1 |
| Chen, M; Gupta, M; Gupta, MP; Pillai, JB; Pillai, VB; Rajamohan, SB; Samant, S | 1 |
| Aubin, MC; Calderone, A; Clément, R; Gosselin, H; Lajoie, C; Perrault, LP | 1 |
4 review(s) available for resveratrol and Fibrosis
| Article | Year |
|---|---|
The combined therapy of mesenchymal stem cell transplantation and resveratrol for diabetes: Future applications and challenges.
Topics: Diabetes Mellitus; Fibrosis; Glucose; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Resveratrol | 2022 |
Resveratrol and Cardiac Fibrosis Prevention and Treatment.
Topics: Animals; Fibrosis; Heart; Humans; Myocardial Infarction; Myocardium; Resveratrol; Stilbenes | 2022 |
Anti-inflammatory and antifibrotic effects of resveratrol in the lung.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Asthma; Disease Models, Animal; Fibrosis; Humans; Inflammation; Liver Diseases; Lung; Mice; Pulmonary Disease, Chronic Obstructive; Resveratrol; Stilbenes | 2015 |
AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation.
Topics: Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Berberine; Cardiomegaly; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Humans; Metformin; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Resveratrol; Ribonucleotides; Signal Transduction; Stilbenes; Thiazolidinediones; Wound Healing | 2016 |
1 trial(s) available for resveratrol and Fibrosis
| Article | Year |
|---|---|
Effects of resveratrol supplementation on cardiac remodeling in hypertensive patients: a randomized controlled clinical trial.
Topics: Ankle Brachial Index; Dietary Supplements; Fibrosis; Humans; Hypertension; Pulse Wave Analysis; Resveratrol; Ventricular Function, Left; Ventricular Remodeling | 2023 |
69 other study(ies) available for resveratrol and Fibrosis
| Article | Year |
|---|---|
Activation of SIRT1 by Resveratrol Alleviates Pressure Overload-Induced Cardiac Hypertrophy via Suppression of TGF-β1 Signaling.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Hemodynamics; Hypertrophy, Left Ventricular; Male; Muscle Cells; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Sirtuin 1; Smad3 Protein; Transforming Growth Factor beta1; Ventricular Function | 2021 |
[Effect of resveratrol on PTEN expression and fibrosis of renal tubular epithelial cells in a high-glucose environment].
Topics: Animals; Epithelial Cells; Fibrosis; Glucose; PTEN Phosphohydrolase; Rats; Resveratrol | 2021 |
Resveratrol ameliorates myocardial fibrosis by regulating Sirt1/Smad3 deacetylation pathway in rat model with dilated cardiomyopathy.
Topics: Animals; Biopsy; Cardiomyopathy, Dilated; Disease Models, Animal; Echocardiography; Enzyme Inhibitors; Fibrosis; Gene Expression Regulation; Male; Myocardium; Resveratrol; RNA; Sirtuin 1; Smad3 Protein; Swine | 2022 |
Pterostilbene, a Resveratrol Derivative, Improves Ectopic Lipid Deposition in the Kidneys of Mice Induced by a High-Fat Diet.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Fibrosis; Kidney; Lipids; Mice; Resveratrol; Stilbenes; Transforming Growth Factor beta1 | 2022 |
Folic acid-targeted pluronic F127 micelles improve oxidative stress and inhibit fibrosis for increasing AKI efficacy.
Topics: Acute Kidney Injury; Apoptosis; Cisplatin; Curcumin; Fibrosis; Folic Acid; Humans; Micelles; Oxidative Stress; Poloxamer; Resveratrol | 2022 |
Luteolin can ameliorate renal interstitial fibrosis-induced renal anaemia through the SIRT1/FOXO3 pathway.
Topics: Anemia; Animals; Fibrosis; Kidney Diseases; Luteolin; Mice; Molecular Docking Simulation; Resveratrol; Sirtuin 1 | 2022 |
Resveratrol Ameliorates Fibrosis in Rheumatoid Arthritis-Associated Interstitial Lung Disease via the Autophagy-Lysosome Pathway.
Topics: Animals; Arthritis, Rheumatoid; Autophagy; Fibrosis; Lung Diseases, Interstitial; Pulmonary Fibrosis; Resveratrol | 2022 |
Resveratrol plays an anti-fibrotic and anti-autophagy role by stimulating miR-192-5p expression in urethral fibrosis.
Topics: Animals; Fibrosis; MicroRNAs; Rats; Rats, Sprague-Dawley; Resveratrol; Up-Regulation | 2023 |
Resveratrol inhibits TGF-β1-induced fibrotic effects in human pterygium fibroblasts.
Topics: Cells, Cultured; Fibroblasts; Fibrosis; Humans; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pterygium; Resveratrol; Transforming Growth Factor beta1 | 2023 |
Resveratrol suppresses the myofibroblastic phenotype and fibrosis formation in kidneys via proliferation-related signalling pathways.
Topics: Animals; Antioxidants; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibroblasts; Fibrosis; Kidney; Kidney Tubules; Myofibroblasts; Rats; Rats, Sprague-Dawley; Resveratrol; Signal Transduction; Ureteral Obstruction | 2019 |
Resveratrol Inhibits Wound Healing and Lens Fibrosis: A Putative Candidate for Posterior Capsule Opacification Prevention.
Topics: Actins; Antioxidants; Biomarkers; Blotting, Western; Capsule Opacification; Cell Line; Cell Movement; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Immunohistochemistry; Lens Capsule, Crystalline; Lens, Crystalline; Models, Biological; Posterior Capsule of the Lens; Real-Time Polymerase Chain Reaction; Resveratrol; Transforming Growth Factor beta2; Wound Healing | 2019 |
Resveratrol Attenuates Pressure Overload-Induced Cardiac Fibrosis and Diastolic Dysfunction via PTEN/AKT/Smad2/3 and NF-κB Signaling Pathways.
Topics: Animals; Cardiotonic Agents; Diastole; Fibrosis; Heart; Male; Mice, Inbred C57BL; Myocarditis; Myocardium; NF-kappa B; Oxidative Stress; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Resveratrol; Signal Transduction; Smad2 Protein; Smad3 Protein | 2019 |
Sirt1 inhibits renal tubular cell epithelial-mesenchymal transition through YY1 deacetylation in diabetic nephropathy.
Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Epithelial-Mesenchymal Transition; Fibrosis; Gene Knockdown Techniques; Glucose; Heterocyclic Compounds, 4 or More Rings; Humans; Male; Mice; Resveratrol; Sirtuin 1; YY1 Transcription Factor | 2021 |
Resveratrol reduces gentamicin-induced EMT in the kidney via inhibition of reactive oxygen species and involving TGF-β/Smad pathway.
Topics: Animals; Biomarkers; Epithelial-Mesenchymal Transition; Fibrosis; Gentamicins; Kidney; Male; Mice; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Signal Transduction; Smad Proteins; Time Factors; Transforming Growth Factor beta | 2020 |
Resveratrol reduces inflammation-related Prostate Fibrosis.
Topics: Adult; Fibrosis; Humans; Inflammation; Lower Urinary Tract Symptoms; Male; Middle Aged; Prostate; Prostatic Hyperplasia; Quality of Life; Resveratrol; Severity of Illness Index; Surveys and Questionnaires | 2020 |
Resveratrol Pretreatment Ameliorates Concanavalin A-Induced Advanced Renal Glomerulosclerosis in Aged Mice through Upregulation of Sirtuin 1-Mediated Klotho Expression.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Animals; Cell Line; Concanavalin A; Fibronectins; Fibrosis; Glucuronidase; Kidney; Kidney Diseases; Klotho Proteins; Male; Mesangial Cells; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Signal Transduction; Sirtuin 1; Superoxide Dismutase; Up-Regulation | 2020 |
Resveratrol Ameliorates Systemic Sclerosis via Suppression of Fibrosis and Inflammation Through Activation of SIRT1/mTOR Signaling.
Topics: Bleomycin; Cells, Cultured; Fibrosis; Humans; Inflammation; Resveratrol; Scleroderma, Systemic; Signal Transduction; Sirtuin 1; TOR Serine-Threonine Kinases | 2020 |
Comparative and Combinatorial Effects of Resveratrol and Sacubitril/Valsartan alongside Valsartan on Cardiac Remodeling and Dysfunction in MI-Induced Rats.
Topics: Aminobutyrates; Animals; Biphenyl Compounds; Drug Combinations; Drug Interactions; Fibrosis; Humans; Male; Myocardial Infarction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Resveratrol; Valsartan; Ventricular Function, Left; Ventricular Remodeling | 2021 |
Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis.
Topics: Animals; beta Catenin; Chronic Disease; Fibrosis; Male; Prostate; Prostatitis; Proto-Oncogene Proteins c-kit; Rats, Sprague-Dawley; Resveratrol; Stem Cell Factor; Stilbenes; Transforming Growth Factor beta; Urinary Bladder, Overactive; Wnt Proteins | 2017 |
Resveratrol Attenuates Adriamycin-Induced Focal Segmental Glomerulosclerosis through C3aR/C5aR- Sphingosine Kinase 1 Pathway.
Topics: Animals; Anti-Inflammatory Agents; Doxorubicin; Fibrosis; Glomerulosclerosis, Focal Segmental; Kidney; Male; Mice; Mice, Inbred BALB C; Phosphotransferases (Alcohol Group Acceptor); Receptor, Anaphylatoxin C5a; Receptors, G-Protein-Coupled; Resveratrol; Signal Transduction; Stilbenes | 2017 |
Resveratrol improved detrusor fibrosis induced by mast cells during progression of chronic prostatitis in rats.
Topics: Animals; Chronic Disease; Collagen; Down-Regulation; Fibrosis; Male; Mast Cells; Muscle, Smooth; Prostatitis; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Transforming Growth Factor beta; Urinary Bladder; Urinary Bladder, Overactive; Wnt Signaling Pathway | 2017 |
Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis by mast cell suppression.
Topics: Animals; Biomarkers; Chronic Disease; Disease Models, Animal; Fibrosis; Humans; Male; Mast Cells; Prostatic Diseases; Prostatitis; Resveratrol; Stilbenes; Transforming Growth Factor beta; Tryptases; Urologic Diseases; Wnt Signaling Pathway | 2018 |
Resveratrol Ameliorates the Severity of Fibrogenesis in Mice with Experimental Chronic Pancreatitis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Carrier Proteins; Cell Survival; Cells, Cultured; Extracellular Matrix; Fibrosis; Male; Mice; Mice, Inbred C57BL; Nuclear Receptor Subfamily 1, Group F, Member 3; p38 Mitogen-Activated Protein Kinases; Pancreas; Pancreatic Stellate Cells; Pancreatitis, Chronic; Proto-Oncogene Proteins c-akt; Resveratrol | 2018 |
The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system.
Topics: Age Factors; Aging; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; Aorta, Thoracic; Cells, Cultured; Cellular Senescence; Fibrosis; Gene Expression Regulation; Male; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR alpha; Renin-Angiotensin System; Resveratrol; Signal Transduction; Sirtuin 1 | 2018 |
Resveratrol prevents atrial fibrillation by inhibiting atrial structural and metabolic remodeling in collagen-induced arthritis rats.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Anti-Arrhythmia Agents; Arthritis, Experimental; Atrial Fibrillation; Atrial Remodeling; Female; Fibrosis; Glycogen; Heart Atria; Interleukin-6; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Protein Kinases; Rats, Wistar; Resveratrol; Tumor Necrosis Factor-alpha | 2018 |
Effects of Resveratrol on the Renin-Angiotensin System in the Aging Kidney.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Collagen Type IV; Fibronectins; Fibrosis; Kidney; Male; Mice, Inbred C57BL; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Plant Extracts; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renal Insufficiency, Chronic; Renin-Angiotensin System; Resveratrol; Superoxide Dismutase | 2018 |
Combined treatment with systemic resveratrol and resveratrol preconditioned mesenchymal stem cells, maximizes antifibrotic action in diabetic cardiomyopathy.
Topics: Animals; Antioxidants; Bone Malalignment; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Random Allocation; Rats; Rats, Wistar; Resveratrol | 2019 |
Activators of SIRT1 in wound repair: an animal model study.
Topics: Animals; Caloric Restriction; Collagen; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Fibrosis; Male; Rats, Wistar; Resveratrol; Signal Transduction; Sirtuin 1; Skin; Time Factors; Wound Healing; Wounds, Penetrating | 2019 |
Resveratrol exerts dose-dependent anti-fibrotic or pro-fibrotic effects in kidneys: A potential risk to individuals with impaired kidney function.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Kidney; Kidney Tubules, Proximal; Male; Mice, Inbred C57BL; Mitochondria; Resveratrol; Sirtuin 1; Smad3 Protein; Transforming Growth Factor beta; Ureteral Obstruction | 2019 |
A novel resveratrol analog PA19 attenuates obesity‑induced cardiac and renal injury by inhibiting inflammation and inflammatory cell infiltration.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Diet, High-Fat; Fibrosis; Heart; Heart Injuries; Inflammation; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Obesity; Resveratrol | 2019 |
Resveratrol alleviates chronic "real-world" ambient particulate matter-induced lung inflammation and fibrosis by inhibiting NLRP3 inflammasome activation in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Enzyme Inhibitors; Fibrosis; Inflammasomes; Leucine-Rich Repeat Proteins; Lung; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Particulate Matter; Pneumonia; Proteins; Pulmonary Fibrosis; Resveratrol; Signal Transduction; Transforming Growth Factor beta1 | 2019 |
SIRT1 activation attenuates cardiac fibrosis by endothelial-to-mesenchymal transition.
Topics: Animals; Cardiomegaly; Cell Line; Cell Nucleus; Collagen; Down-Regulation; Endothelium; Fibrosis; Isoproterenol; Male; Mesoderm; Mice, Inbred C57BL; Models, Biological; Myocardium; Phosphorylation; Protein Transport; Resveratrol; Sirtuin 1; Smad Proteins; Transforming Growth Factor beta | 2019 |
Resveratrol as a therapeutic agent for renal fibrosis induced by unilateral ureteral obstruction.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Deoxyguanosine; Fibronectins; Fibrosis; Intercellular Adhesion Molecule-1; Kidney; Kidney Glomerulus; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Reactive Oxygen Species; Resveratrol; Smad3 Protein; Stilbenes; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Ureteral Obstruction | 2014 |
Sirt1 activation ameliorates renal fibrosis by inhibiting the TGF-β/Smad3 pathway.
Topics: Animals; Fibrosis; Humans; Mice; Rats; Renal Insufficiency, Chronic; Resveratrol; Signal Transduction; Sirtuin 1; Smad3 Protein; Stilbenes; Transforming Growth Factor beta1 | 2014 |
Impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede development of diabetic cardiomyopathy are prevented by resveratrol in ZDF rats.
Topics: Animals; Cardiotonic Agents; Diabetic Cardiomyopathies; Electron Transport Chain Complex Proteins; Fibrosis; Glutathione; Glutathione Disulfide; Heart Ventricles; Kinetics; Lipid Metabolism; Male; Mitochondria, Heart; Palmitoyl Coenzyme A; Rats, Zucker; Resveratrol; Stilbenes; Ventricular Function, Left | 2014 |
Mitochondrial aldehyde dehydrogenase 2 accentuates aging-induced cardiac remodeling and contractile dysfunction: role of AMPK, Sirt1, and mitochondrial function.
Topics: Aging; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; AMP-Activated Protein Kinases; Animals; Apoptosis; Atrial Remodeling; Benzamides; Benzodioxoles; Calcium; Cardiomegaly; Fibrosis; Gene Expression Regulation; Heterocyclic Compounds, 4 or More Rings; Ion Channels; Mice; Mice, Transgenic; Mitochondria, Heart; Mitochondrial Proteins; Myocardial Contraction; Myocardium; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Superoxides; Transcription Factors; Uncoupling Protein 2 | 2014 |
Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts.
Topics: Animals; Cell Line; Colitis; Collagen Type I; Colon; Disease Models, Animal; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibrosis; Insulin-Like Growth Factor I; Male; MAP Kinase Kinase Kinases; Mice; Mutation; Phosphorylation; Rats, Sprague-Dawley; Receptor, IGF Type 1; Resveratrol; RNA Interference; RNA, Messenger; Signal Transduction; Sirtuin 1; Stilbenes; Transfection; Trinitrobenzenesulfonic Acid | 2014 |
Protective effect of resveratrol against doxorubicin-induced cardiac toxicity and fibrosis in male experimental rats.
Topics: Animals; Antioxidants; Cardiotonic Agents; Cardiotoxicity; Caspase 3; Doxorubicin; Fibrosis; Gene Expression; Glutathione; Heart; Heart Ventricles; Male; Rats; Rats, Wistar; Resveratrol; RNA, Messenger; Stilbenes; Superoxide Dismutase; Transforming Growth Factor beta1; Ventricular Remodeling | 2014 |
Inhibition of STAT3 acetylation is associated with angiotesin renal fibrosis in the obstructed kidney.
Topics: Acetylation; Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cell Line; Fibrosis; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; Phosphorylation; Rats; Resveratrol; Signal Transduction; STAT3 Transcription Factor; Stilbenes | 2014 |
Resveratrol inhibits epithelial-mesenchymal transition and renal fibrosis by antagonizing the hedgehog signaling pathway.
Topics: Animals; Cell Line; Disease Models, Animal; Epithelial-Mesenchymal Transition; Extracellular Matrix; Fibrosis; Hedgehog Proteins; Kidney; Kidney Tubules; Male; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Resveratrol; Signal Transduction; Smoothened Receptor; Stilbenes; Transforming Growth Factor beta1; Ureteral Obstruction | 2014 |
Activation of SIRT3 by resveratrol ameliorates cardiac fibrosis and improves cardiac function via the TGF-β/Smad3 pathway.
Topics: Animals; Cardiomegaly; Cells, Cultured; Collagen; Fibrosis; Heart; Male; Mice; Myocardium; Myocytes, Cardiac; Myofibroblasts; Resveratrol; Sirtuin 3; Smad3 Protein; Stilbenes; Transforming Growth Factor beta | 2015 |
Resveratrol Regulates the Quiescence-Like Induction of Activated Stellate Cells by Modulating the PPARγ/SIRT1 Ratio.
Topics: Animals; Cell Proliferation; Fibrosis; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Kupffer Cells; Lipid Droplets; Lipogenesis; Liver; Mice; Myoblasts; PPAR gamma; Resveratrol; RNA, Messenger; Sirtuin 1; Stilbenes; Vitamin A | 2015 |
Anti-fibrotic effect of trans-resveratrol on pancreatic stellate cells.
Topics: Animals; Cell Death; Cell Line; Fibronectins; Fibrosis; NF-kappa B; Pancreatic Stellate Cells; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Resveratrol; Signal Transduction; Stilbenes | 2015 |
Resveratrol Attenuated Low Ambient Temperature-Induced Myocardial Hypertrophy via Inhibiting Cardiomyocyte Apoptosis.
Topics: Animals; Apoptosis; Cardiomegaly; Caspase 3; Cold Temperature; Fibrosis; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Myocardium; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Resveratrol; Signal Transduction; Stilbenes; Up-Regulation | 2015 |
Resveratrol Upregulates Cardiac SDF-1 in Mice with Acute Myocardial Infarction through the Deacetylation of Cardiac p53.
Topics: Acetylation; Animals; Cell Hypoxia; Chemokine CXCL12; Fibrosis; Gene Silencing; Heart Function Tests; Heart Ventricles; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Resveratrol; Sirtuin 1; Stilbenes; Tumor Suppressor Protein p53; Ultrasonography; Up-Regulation | 2015 |
Resveratrol attenuates renal injury and fibrosis by inhibiting transforming growth factor-β pathway on matrix metalloproteinase 7.
Topics: Acute Kidney Injury; Animals; Cell Line; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Male; Matrix Metalloproteinase 7; Matrix Metalloproteinase Inhibitors; Mice, Inbred C57BL; Resveratrol; Stilbenes; Transforming Growth Factor beta | 2016 |
Resveratrol Prevents High Fluence Red Light-Emitting Diode Reactive Oxygen Species-Mediated Photoinhibition of Human Skin Fibroblast Migration.
Topics: Antioxidants; Cell Movement; Cell Proliferation; Cells, Cultured; Fibroblasts; Fibrosis; Humans; Hydrogen Peroxide; Light; Phototherapy; Resveratrol; Skin; Stilbenes | 2015 |
Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy.
Topics: Animals; Cardiomyopathies; Disease Models, Animal; Down-Regulation; Fibroblasts; Fibrosis; Forkhead Box Protein O1; Forkhead Transcription Factors; Genetic Therapy; GPI-Linked Proteins; Hemochromatosis Protein; Humans; Iron Overload; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Models, Genetic; Myocardium; Myocytes, Cardiac; Oxidants; Oxidative Stress; Resveratrol; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Sirtuin 1; Stilbenes | 2015 |
SIRT1 activation attenuates diastolic dysfunction by reducing cardiac fibrosis in a model of anthracycline cardiomyopathy.
Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Cardiomyopathies; Cells, Cultured; Diastole; Disease Models, Animal; Doxorubicin; Female; Fibrosis; Rats; Rats, Inbred F344; Resveratrol; Sirtuin 1; Stilbenes | 2016 |
Resveratrol ameliorates myocardial fibrosis by inhibiting ROS/ERK/TGF-β/periostin pathway in STZ-induced diabetic mice.
Topics: Animals; Antioxidants; Cell Adhesion Molecules; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Heart; Male; MAP Kinase Signaling System; Mice; Myocardium; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes; Transforming Growth Factor beta | 2016 |
Resveratrol ameliorates fibrosis and inflammation in a mouse model of nonalcoholic steatohepatitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Disease Models, Animal; Fibrosis; Fluorescent Antibody Technique; Gene Expression; Humans; Immunoblotting; Inflammation; Interleukin-6; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; STAT3 Transcription Factor; Stilbenes; Tumor Necrosis Factor-alpha | 2016 |
Regulation of eIF2α expression and renal interstitial fibrosis by resveratrol in rat renal tissue after unilateral ureteral obstruction.
Topics: Animals; Eukaryotic Initiation Factor-2; Fibrosis; Kidney; Male; Rats; Rats, Wistar; Resveratrol; Stilbenes; Ureteral Obstruction | 2016 |
The role of metformin and resveratrol in the prevention of hypoxia-inducible factor 1α accumulation and fibrosis in hypoxic adipose tissue.
Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fibrosis; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Male; Metformin; Mice; Mice, Inbred ICR; Resveratrol; Stilbenes; Structure-Activity Relationship | 2016 |
Resveratrol ameliorates renal injury in spontaneously hypertensive rats by inhibiting renal micro-inflammation.
Topics: Acute Kidney Injury; Animals; beta 2-Microglobulin; Blood Pressure; Collagen Type I; Disease Models, Animal; Fibronectins; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Inflammation; Kidney; Plasminogen Activator Inhibitor 1; Rats; Resveratrol; Stilbenes; Transforming Growth Factor beta1 | 2016 |
Resveratrol inhibits renal interstitial fibrosis in diabetic nephropathy by regulating AMPK/NOX4/ROS pathway.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Cell Differentiation; Cell Line; Cell Proliferation; Diabetic Nephropathies; Fibroblasts; Fibrosis; Gene Expression Regulation; Glucose; Kidney; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myofibroblasts; NADPH Oxidase 4; Rats; Reactive Oxygen Species; Resveratrol; Signal Transduction; Stilbenes | 2016 |
Reduced HMGB 1-Mediated Pathway and Oxidative Stress in Resveratrol-Treated Diabetic Mice: A Possible Mechanism of Cardioprotection of Resveratrol in Diabetes Mellitus.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Fibrosis; Heart; HMGB1 Protein; Inflammation; Male; Membrane Glycoproteins; Mice; Monocytes; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Protective Agents; Resveratrol; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Stilbenes | 2016 |
Long-term low dose dietary resveratrol supplement reduces cardiovascular structural and functional deterioration in chronic heart failure in rats.
Topics: Animals; Cardiotonic Agents; Chronic Disease; Collagen; Dietary Supplements; Disease Models, Animal; Drug Administration Schedule; Echocardiography; Fibrosis; Heart Failure; Male; Myocardial Contraction; Myocardium; Pulse Wave Analysis; Rats, Wistar; Resveratrol; Stilbenes; Stroke Volume; Time Factors; Vascular Stiffness; Ventricular Function, Left; Ventricular Remodeling | 2017 |
A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds.
Topics: Aging; Ascorbic Acid; Cell Line; Citric Acid; Collagen Type I; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Fibrosis; Glycolates; Humans; Lactic Acid; Linoleic Acids, Conjugated; Resveratrol; Stilbenes; Undecylenic Acids; Vitamin A | 2008 |
Resveratrol attenuates angiotensin II-induced interleukin-6 expression and perivascular fibrosis.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Blotting, Northern; Blotting, Western; Body Weight; Cells, Cultured; DNA; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Fibrosis; Heart Rate; Interleukin-6; Luciferases; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Promoter Regions, Genetic; Rats; Resveratrol; Stilbenes; Vascular Diseases | 2009 |
[Effect of resveratrol on myocardial fibrosis in mice with chronic viral myocarditis].
Topics: Animals; Chronic Disease; Collagen Type I; Collagen Type II; Coxsackievirus Infections; Enterovirus B, Human; Fibrosis; Male; Mice; Mice, Inbred BALB C; Myocarditis; Myocardium; Peptide Fragments; Procollagen; Resveratrol; Stilbenes | 2009 |
Effect of resveratrol on tubular damage and interstitial fibrosis in kidneys of rats exposed to cigarette smoke.
Topics: Animals; Antioxidants; Fibrosis; Injections, Intraperitoneal; Kidney; Kidney Tubules; Male; Photomicrography; Rats; Rats, Wistar; Resveratrol; Smoking; Stilbenes | 2009 |
Sirt1 activation protects the mouse renal medulla from oxidative injury.
Topics: Animals; Apoptosis; Cells, Cultured; Cyclooxygenase 2; Fibrosis; Heterocyclic Compounds, 4 or More Rings; Kidney Medulla; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Resveratrol; Sirtuin 1; Stilbenes; Ureteral Obstruction | 2010 |
Resveratrol inhibits renal fibrosis in the obstructed kidney: potential role in deacetylation of Smad3.
Topics: Acetylation; Analysis of Variance; Animals; Blotting, Western; Cells, Cultured; Epithelial Cells; Fibroblasts; Fibrosis; Immunoprecipitation; Kidney; Mice; Microscopy, Confocal; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sirtuin 1; Smad3 Protein; Stilbenes; Transforming Growth Factor beta1 | 2010 |
Resveratrol improves cardiovascular function in DOCA-salt hypertensive rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cardiovascular Diseases; Cardiovascular Physiological Phenomena; Desoxycorticosterone; Fibrosis; Heart; Heart Ventricles; Humans; Hypertension; Male; Mineralocorticoids; Rats; Rats, Wistar; Resveratrol; Sodium Chloride, Dietary; Stilbenes; Ventricular Remodeling | 2011 |
Resveratrol ameliorates muscular pathology in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy.
Topics: Animals; Antioxidants; Blotting, Western; Cell Differentiation; Cell Line; Creatine Kinase; Electroporation; Fibroblasts; Fibrosis; Histones; Immunohistochemistry; Indicators and Reagents; L-Lactate Dehydrogenase; Mice; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Oxidative Stress; Reactive Oxygen Species; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Sirtuin 1; Stilbenes | 2011 |
Resveratrol has antiinflammatory and antifibrotic effects in the peptidoglycan-polysaccharide rat model of Crohn's disease.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colon; Crohn Disease; Cytokines; Disease Models, Animal; Female; Fibrosis; Ileum; Peptidoglycan; Polysaccharides; Procollagen; Rats; Rats, Inbred Lew; Resveratrol; Serum Albumin; Stilbenes | 2012 |
Chronic resveratrol treatment protects pancreatic islets against oxidative stress in db/db mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Blood Glucose; Deoxyguanosine; Diabetes Mellitus, Type 2; Disease Models, Animal; Fibrosis; Glucose Tolerance Test; Immunohistochemistry; Insulin; Insulin Resistance; Islets of Langerhans; Male; Mice; Organ Size; Oxidative Stress; Resveratrol; Stilbenes | 2012 |
Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the alpha-myosin heavy chain expression.
Topics: Animals; Antioxidants; Antithyroid Agents; Blotting, Western; Cardiomegaly; Cell Size; Cells, Cultured; Densitometry; Diet; Enzyme Activation; Fibrosis; Fructose; Male; Mice; Mice, Transgenic; Myocardium; Myosin Heavy Chains; NAD; Nutritional Physiological Phenomena; Propylthiouracil; Resveratrol; RNA; Sirtuin 1; Sirtuins; Stilbenes; Transfection | 2008 |
Female rats fed a high-fat diet were associated with vascular dysfunction and cardiac fibrosis in the absence of overt obesity and hyperlipidemia: therapeutic potential of resveratrol.
Topics: Acetylcholine; Animals; Antioxidants; Aorta; Blood Pressure; Dietary Fats; Female; Fibrosis; Hyperlipidemias; Myocardium; Nitroprusside; Obesity; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Vasodilation; Vasodilator Agents; Ventricular Dysfunction, Left | 2008 |