Compounds > resveratrol
Page last updated: 2024-08-16

resveratrol and Colorectal Neoplasms

resveratrol has been researched along with Colorectal Neoplasms in 86 studies

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.16)18.2507
2000's12 (13.95)29.6817
2010's53 (61.63)24.3611
2020's20 (23.26)2.80

Authors

AuthorsStudies
Čumová, A; Opattová, A; Rejhová, A; Slíva, D; Vodička, P1
Qian, Y; Wang, M; Wang, R; Wang, S; Wei, W1
Akhtari, N; Behzad, S; Hashemi, A; Khankandi, HP; Mashhadi, M; Rezaee, Y; Rezaei, S; Shiranirad, S; Vernousfaderani, EK1
Biganeh, H; Dizaji, SM; Murtaza, G; Rahimi, R; Taghipour, YD1
Abdel-Naim, AB; Al-Sawahli, MM; Alolayan, EM; El-Halawany, AM; El-Telbany, DFA; El-Telbany, RFA; Elkhatib, WF; Hammad, SF; Khayat, MT; Khayyat, AN; Kutbi, HI; Noreddin, AM; Zarka, MA1
Greenlee, JD; King, MR; Liu, K; Lopez-Cavestany, M1
Bando, M; Fujimoto, S; Horimoto, K; Kawaguchi, T; Matsuzawa, Y; Miyamoto, H; Muguruma, N; Mutoh, M; Okamoto, K; Sato, Y; Takayama, T; Wada, H1
Farhood, B; Huan, XK; Tian, J; Wu, XY; Xu, WW; Zhai, J1
Cichoń, T; Czapla, J; Drzyzga, A; Matuszczak, S; Pilny, E; Smolarczyk, R; Stojecki, K1
Brockmueller, A; Girisa, S; Kunnumakkara, AB; Shakibaei, M1
Han, CL; Li, F; Li, KY; Liu, M; Shen, H; Wang, J; Wang, L; Yan, RY1
Brockmueller, A; Buhrmann, C; Shakibaei, M; Shayan, P2
Arikawa, N; Doi, S; Kotake, Y; Matsukawa, T; Matsunaga, N; Ohnuki, K; Sawata, Y; Shirasawa, S; Tsunoda, T1
Aires, V; Artur, Y; Colin, DJ; Delmas, D; Di Pietro, A; Doreau, A; Heydel, JM; Latruffe, N1
Chen, X; Fang, A; Mao, F; Wang, G; Wang, J; Wu, K; Zhang, Z1
Alam, A; Behera, SK; Dariya, B; Farran, B; Nagaraju, GP; Srivani, G1
Chiang, HC; Han, W; Hsieh, PJ; Huang, CC; Ke, CH; Kuo, IM; Lee, JJ; Liao, ATC; Lin, CS; Wang, YS1
Gupta, N; Jain, P; Jangid, AK; Kulhari, H; Patel, K; Patel, S; Pooja, D1
Alam, A; Aliya, S; Behera, SK; Dariya, B; Nagaraju, GP; Srivani, G1
Feng, F; Fu, Y; Jiang, S; Li, Y; Sun, J; Wen, Z; Wu, H; Xu, Y; Ye, Y; Zhang, Q; Zhu, G1
Cardona-G, W; Hernández, C; Herrera-R, A; Moreno, G1
Gąsiorowski, K; Szafran, RG; Wiatrak, B1
Gong, WH; Li, JB; Yan, L; Zhang, YX; Zhang, ZM; Zhao, N1
Doonan, BB; Hsieh, TC; Pinto, JT; Schaafsma, E; Wu, JM1
Doi, S; Kotake, Y; Matsukawa, T; Naemura, M; Ohnuki, K; Okamoto, H; Sawata, Y; Shirasawa, S; Tsunoda, T1
Buhrmann, C; Goel, A; Shakibaei, M; Shayan, P1
Calviello, G; Cassano, R; Corsetto, PA; Rizzo, AM; Serini, S; Trombino, S1
Jin, H; Kim, SM; Kim, SZ; Kim, WJ; Kim, WT; Lee, SR; Leem, SH1
Chen, Y; Elshaer, M; Tang, X; Wang, XJ1
Aggarwal, BB; Buhrmann, C; Goel, A; Popper, B; Shakibaei, M; Shayan, P; Yazdi, M2
Chen, YR; Cheng, TM; Chin, YT; Davis, PJ; Hercbergs, A; Ho, Y; Incerpi, S; Li, WS; Liao, YM; Lin, HY; Liu, LF; Liu, YR; Nana, AW; Pedersen, J; Shih, YJ; Whang-Peng, J; Wu, SY; Yang, YS1
Kim, DU; Kim, SW; Kwak, B1
Aggarwal, BB; Buhrmann, C; Kunnumakkara, AB; Popper, B; Shakibaei, M; Yazdi, M1
Balacescu, O; Cruceriu, D; Gavrilas, LI; Ionescu, C; Miere, D1
Andreadi, C; Brenner, DE; Britton, RG; Brown, K; Brown, VA; Gescher, AJ; Horner-Glister, E; Karmokar, A; Patel, KR; Sale, S; Singh, R; Steward, WP1
Cai, J; Fu, X; Ji, Q; Li, Q; Liu, X; Qin, J; Ren, J; Sui, H; Sun, J; Zhang, L; Zhou, L1
Andreadi, C; Britton, RG; Brown, K; Patel, KR1
Abdelazeem, AH; Arab, HH; Arafa, el-SA; Omar, HA1
Brecht, K; Brüne, B; Gilbert, B; Kaminski, BM; Ley, S; Scherzberg, MC; Stein, J; Steinhilber, D; Ulrich-Rückert, S; Weigert, A1
Chalal, M; Delmas, D; Latruffe, N; Meunier, P; Vervandier-Fasseur, D1
Andreoli, SC; de Andrade, RV; de Carvalho, GP; Garicochea, B; Gasparini, NJ; Pogue, RE1
Ali, I; Braun, DP1
Colburn, NH; Kim, YS; Li, W; Matter, MS; Morris, NL; Saud, SM; Young, MR1
Akimoto, K; Inoue, K; Kubota, K; Shibuya, N; Tanaka, G1
Espín, JC; García-Conesa, MT; García-Villalba, R; González-Sarrías, A; Núñez-Sánchez, MA; Romo-Vaquero, M; Selma, MV; Tomás-Barberán, FA1
Al-Harthi, SE; Al-Malki, HS; El-Hanafy, AA; Elashmaoui, HM; Elshal, MF; Osman, AM1
Cai, J; Han, Z; Ji, Q; Jiang, H; Li, Q; Liu, X; Ren, J; Sui, H; Yan, L; Zhou, L1
Jeong, JB; Lee, J; Lee, SH1
Cheng, Z; Gao, H; Ni, Z; Sun, J; Wang, Z; Xu, J; Yin, P; Zhang, L1
Andreadi, C; Britton, RG; Brown, K; Cai, H; Gescher, AJ; Goldring, C; Greaves, P; Hemingway, D; Horner-Glister, E; Howells, L; James, M; Jawad, D; Karmokar, A; Kholghi, A; Kitteringham, N; Malfatti, M; Miller, A; Ognibene, T; Rufini, A; Scott, E; Steward, WP; Viskaduraki, M; Walsh, J; West, K1
Buhrmann, C; Goel, A; Kraehe, P; Popper, B; Shakibaei, M; Shayan, P1
Chang, H; Ji, F; Li, W; Shen, P; Sun, H; Sun, T; Wang, Y; Wu, B; Yang, S; Zhou, D1
Buhrmann, C; Goel, A; Popper, B; Shakibaei, M; Shayan, P1
Brown, K; Gescher, A; Rufini, A1
Lin, YM; Qing, Y; Wang, M; Wu, D; Yin, TF1
Amini, R; Heydari, K; Karimi Dermani, F; Mahdavinezhad, A; Najafi, R; Saidijam, M1
Daniel, H; Juan, ME; Planas, JM; Wenzel, U1
Duessel, S; Ezekiel, UR; Heuertz, RM1
Chang, JC; Chiou, RY; Li, AF; Liao, HF; Weng, YL1
Che, CT; Cho, CH; Li, H; Li, ZJ; Sung, JJ; Wang, M; Wong, CC; Wu, WK; Xu, DD; Ye, CG; Zheng, Z1
Booth, TD; Brenner, DE; Britton, RG; Brown, K; Brown, VA; Crowell, JA; Gescher, AJ; Hemingway, D; Jones, DJ; Miller, AS; Patel, KR; Perloff, M; Steward, WP; West, KP1
Majumdar, AP; Misra, S; Patel, BB; Patel, VB1
Baek, SJ; Bahn, JH; Eling, TE; Lee, SH; Whitlock, NC1
Latruffe, N1
Araújo, JR; Gonçalves, P; Martel, F1
Iwuchukwu, OF; Nagar, S; Tallarida, RJ1
Alston-Mills, B; Bottone, FG1
Choudhuri, M; Choudhuri, T; Kundu, CN; Mohapatra, P; Preet, R1
Birt, DF; Boddicker, RL; Davis, JE; Spurlock, ME; Whitley, EM1
Boghossian, S; Hawash, A1
Alfaras, I; Juan, ME; Planas, JM1
Bian, Z; Gou, X; Jia, W; Kou, F; Liao, W; Qiu, Y; Wang, X; Wei, H; Wu, J; Wu, T; Xie, G; Zhang, X; Zhang, Y; Zhou, M1
Hull, MA1
Cherkaoui Malki, M; Delmas, D; Jannin, B; Latruffe, N; Passilly-Degrace, P1
Köhler, H; Mahyar-Roemer, M; Roemer, K1
Boocock, D; Farmer, PB; Gescher, AJ; Jones, DJ; Potter, GA; Ruparelia, KC; Sale, S; Steward, WP; Verschoyle, RD; Wilsher, N1
Stein, J; Ulrich, S; Wolter, F1
Vermel', AE1
Alston-Mills, B; Bottone, FG; Eling, TE; Ishibashi, M; Kim, JS; Moon, Y1
Mahyar-Roemer, M; Pöhland, T; Roemer, K; Wagner, S1
Hausott, B; Klepal, W; Leuhuber, K; Marian, B1
Castino, R; Follo, C; Isidoro, C; Nicotra, G; Trincheri, NF1
Gottlieb, N1
Caderni, G; Davit, A; Sarotto, I; Tessitore, L1

Reviews

15 review(s) available for resveratrol and Colorectal Neoplasms

ArticleYear
Natural compounds and combination therapy in colorectal cancer treatment.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Products; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship

2018
Resveratrol and Colorectal Cancer: A Molecular Approach to Clinical Researches.
    Current topics in medicinal chemistry, 2021, Volume: 21, Issue:29

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Colorectal Neoplasms; Drug Delivery Systems; Humans; Neuroprotective Agents; Resveratrol; Signal Transduction

2021
A Systematic Review of the Therapeutic Potential of Resveratrol During Colorectal Cancer Chemotherapy.
    Mini reviews in medicinal chemistry, 2023, Volume: 23, Issue:10

    Topics: Animals; Antineoplastic Agents; Colorectal Neoplasms; Humans; Resveratrol

2023
Resveratrol: An overview of its anti-cancer mechanisms.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Autophagy; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Female; Humans; Inflammasomes; Male; Mice; Neoplasm Metastasis; NF-E2-Related Factor 2; Phytoalexins; Rats; Resveratrol; Sesquiterpenes; Skin Neoplasms; Stilbenes

2018
Resveratrol-sulfates provide an intracellular reservoir for generation of parent resveratrol, which induces autophagy in cancer cells.
    Autophagy, 2014, Volume: 10, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Autophagy; Cell Line, Tumor; Colorectal Neoplasms; Humans; Intracellular Space; Resveratrol; Stilbenes; Sulfates

2014
Use of microRNAs in directing therapy and evaluating treatment response in colorectal cancer.
    Einstein (Sao Paulo, Brazil), 2014, Volume: 12, Issue:2

    Topics: Antineoplastic Agents; Capecitabine; Chemoradiotherapy, Adjuvant; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Gene Expression Regulation, Neoplastic; Genetic Markers; Humans; MicroRNAs; Neoplasm Invasiveness; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Prognosis; Resveratrol; Stilbenes

2014
Dietary phenolics against colorectal cancer--From promising preclinical results to poor translation into clinical trials: Pitfalls and future needs.
    Molecular nutrition & food research, 2015, Volume: 59, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Clinical Trials as Topic; Colorectal Neoplasms; Curcumin; Diet; Drug Screening Assays, Antitumor; Gastrointestinal Microbiome; Humans; Lythraceae; Phenols; Resveratrol; Stilbenes; Tea; Zingiber officinale

2015
Research progress on chemopreventive effects of phytochemicals on colorectal cancer and their mechanisms.
    World journal of gastroenterology, 2016, Aug-21, Volume: 22, Issue:31

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Cycle Checkpoints; Colorectal Neoplasms; Curcumin; Humans; Neovascularization, Pathologic; NF-E2-Related Factor 2; Phytochemicals; Resveratrol; Stilbenes

2016
Colorectal cancer: chemopreventive role of curcumin and resveratrol.
    Nutrition and cancer, 2010, Volume: 62, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Clinical Trials as Topic; Colorectal Neoplasms; Curcumin; Humans; Resveratrol; Stilbenes

2010
Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines.
    Nutrition research (New York, N.Y.), 2011, Volume: 31, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Apoptosis; Catechin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Diet; Flavonoids; Fruit; Humans; Phenols; Polyphenols; Propiophenones; Quercetin; Resveratrol; Rutin; Stilbenes; Vegetables

2011
Chemoprevention in colorectal cancer--where we stand and what we have learned from twenty year's experience.
    The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland, 2012, Volume: 10, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Anticarcinogenic Agents; Colorectal Neoplasms; Histone Deacetylase Inhibitors; Humans; Metformin; Precancerous Conditions; Resveratrol; Selective Estrogen Receptor Modulators; Stilbenes

2012
Colorectal cancer chemoprevention by trans-resveratrol.
    Pharmacological research, 2012, Volume: 65, Issue:6

    Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Genetic Predisposition to Disease; Humans; Precancerous Conditions; Resveratrol; Stilbenes

2012
Nutritional agents with anti-inflammatory properties in chemoprevention of colorectal neoplasia.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2013, Volume: 191

    Topics: Anti-Inflammatory Agents; Anticarcinogenic Agents; Colorectal Neoplasms; Curcumin; Dietary Supplements; Fatty Acids, Omega-3; Humans; Resveratrol; Stilbenes; Vitamin D

2013
Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in colorectal cancer: key role of polyamines?
    The Journal of nutrition, 2004, Volume: 134, Issue:12

    Topics: Animals; Anticarcinogenic Agents; Colorectal Neoplasms; Humans; Phytotherapy; Polyamines; Resveratrol; Stilbenes; Vitis; Wine

2004
[Pharmacological capacities of the prevention of colorectal cancer].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Calcium; Colorectal Neoplasms; Dietary Fiber; Feeding Behavior; Folic Acid; Humans; Resveratrol; Stilbenes

2004

Trials

2 trial(s) available for resveratrol and Colorectal Neoplasms

ArticleYear
Resveratrol inhibits invasion and metastasis of colorectal cancer cells via MALAT1 mediated Wnt/β-catenin signal pathway.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Aged; Antineoplastic Agents, Phytogenic; beta Catenin; Cell Line, Tumor; Cell Nucleus; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinase 7; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Proto-Oncogene Proteins c-myc; Resveratrol; RNA, Long Noncoding; RNA, Neoplasm; Stilbenes; Wnt Signaling Pathway

2013
Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients.
    Cancer research, 2010, Oct-01, Volume: 70, Issue:19

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Cell Growth Processes; Colorectal Neoplasms; Combined Modality Therapy; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Male; Middle Aged; Resveratrol; Stilbenes

2010

Other Studies

69 other study(ies) available for resveratrol and Colorectal Neoplasms

ArticleYear
Resveratrol reverses the cadmium-promoted migration, invasion, and epithelial-mesenchymal transition procession by regulating the expression of ZEB1.
    Human & experimental toxicology, 2021, Volume: 40, Issue:12_suppl

    Topics: Cadmium; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Down-Regulation; Epithelial-Mesenchymal Transition; Humans; Neoplasm Metastasis; Resveratrol; Up-Regulation; Zinc Finger E-box-Binding Homeobox 1

2021
Nanoformulations of Plant-Derived Compounds as Emerging Therapeutic Approach for Colorectal Cancer.
    Current drug delivery, 2023, Volume: 20, Issue:8

    Topics: Colorectal Neoplasms; Curcumin; Humans; Neovascularization, Pathologic; Phytochemicals; Resveratrol

2023
Intensification of resveratrol cytotoxicity, pro-apoptosis, oxidant potentials in human colorectal carcinoma HCT-116 cells using zein nanoparticles.
    Scientific reports, 2022, Sep-08, Volume: 12, Issue:1

    Topics: Apoptosis; Caco-2 Cells; Caspase 3; Colorectal Neoplasms; HCT116 Cells; Humans; Nanoparticles; Oxidants; Resveratrol; Zein

2022
Piezo1 Mechano-Activation Is Augmented by Resveratrol and Differs between Colorectal Cancer Cells of Primary and Metastatic Origin.
    Molecules (Basel, Switzerland), 2022, Aug-25, Volume: 27, Issue:17

    Topics: Calcium; Calcium Signaling; Colorectal Neoplasms; Humans; Ion Channels; Resveratrol

2022
Resveratrol inhibits development of colorectal adenoma via suppression of LEF1; comprehensive analysis with connectivity map.
    Cancer science, 2022, Volume: 113, Issue:12

    Topics: Adenoma; Animals; Chemoprevention; Colorectal Neoplasms; Lymphoid Enhancer-Binding Factor 1; Mice; Rats; Resveratrol; Wnt Signaling Pathway

2022
The Complex Composition of Trans-resveratrol, Quercetin, Vitamin E and Selenium Inhibits the Growth of Colorectal Carcinoma.
    Anticancer research, 2022, Volume: 42, Issue:10

    Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Line, Tumor; Colorectal Neoplasms; Mice; Quercetin; Resveratrol; Selenium; Vitamin E

2022
Resveratrol Modulates Chemosensitisation to 5-FU via β1-Integrin/HIF-1α Axis in CRC Tumor Microenvironment.
    International journal of molecular sciences, 2023, Mar-05, Volume: 24, Issue:5

    Topics: Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; Humans; Integrin beta1; Resveratrol; Tumor Microenvironment

2023
[Molecular mechanism of resveratrol combined with irinotecan in treatment of colorectal cancer].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2023, Volume: 48, Issue:8

    Topics: Colorectal Neoplasms; ErbB Receptors; Humans; Irinotecan; Molecular Docking Simulation; Resveratrol

2023
Resveratrol induces apoptosis by modulating the reciprocal crosstalk between p53 and Sirt-1 in the CRC tumor microenvironment.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Apoptosis; Colorectal Neoplasms; Resveratrol; Signal Transduction; Sirtuin 1; Tumor Microenvironment; Tumor Suppressor Protein p53

2023
A novel compound, ferulic acid-bound resveratrol, induces the tumor suppressor gene p15 and inhibits the three-dimensional proliferation of colorectal cancer cells.
    Molecular and cellular biochemistry, 2019, Volume: 462, Issue:1-2

    Topics: Cell Proliferation; Colorectal Neoplasms; Coumaric Acids; Cyclin-Dependent Kinase Inhibitor p15; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HCT116 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Resveratrol; RNA, Messenger

2019
P-Glycoprotein 1 Affects Chemoactivities of Resveratrol against Human Colorectal Cancer Cells.
    Nutrients, 2019, Sep-04, Volume: 11, Issue:9

    Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Resveratrol

2019
Resveratrol Attenuates Inflammatory Bowel Disease in Mice by Regulating SUMO1.
    Biological & pharmaceutical bulletin, 2020, Volume: 43, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; beta Catenin; Cell Culture Techniques; Colitis; Colon; Colorectal Neoplasms; Cytokines; Dextran Sulfate; Humans; Inflammatory Bowel Diseases; Mice; Mice, Inbred BALB C; Resveratrol; Spleen; SUMO-1 Protein; Wnt Signaling Pathway

2020
Computational analysis of nuclear factor-κB and resveratrol in colorectal cancer.
    Journal of biomolecular structure & dynamics, 2021, Volume: 39, Issue:8

    Topics: Antioxidants; Colorectal Neoplasms; Humans; Molecular Docking Simulation; NF-kappa B; Resveratrol; Stilbenes

2021
Potential enhancement of host immunity and anti-tumor efficacy of nanoscale curcumin and resveratrol in colorectal cancers by modulated electro- hyperthermia.
    BMC cancer, 2020, Jun-29, Volume: 20, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Availability; Cell Cycle Checkpoints; Cell Line, Tumor; Colorectal Neoplasms; Combined Modality Therapy; Curcumin; Disease Models, Animal; Drug Screening Assays, Antitumor; Electric Stimulation Therapy; Female; Humans; Hyperthermia, Induced; Macrophages; Male; Mice; Nanoparticles; Rats; Resveratrol; T-Lymphocytes; Tumor Microenvironment

2020
Inulin-pluronic-stearic acid based double folded nanomicelles for pH-responsive delivery of resveratrol.
    Carbohydrate polymers, 2020, Nov-01, Volume: 247

    Topics: Antioxidants; Colorectal Neoplasms; Drug Delivery Systems; Drug Liberation; Humans; Hydrogen-Ion Concentration; Inulin; Membrane Potential, Mitochondrial; Micelles; Nanoparticles; Poloxamer; Resveratrol; Stearic Acids; Tumor Cells, Cultured

2020
Resveratrol binds and activates RKIP protein in colorectal cancer.
    Amino acids, 2020, Volume: 52, Issue:9

    Topics: Antioxidants; Cell Proliferation; Colorectal Neoplasms; Humans; Phosphatidylethanolamine Binding Protein; Protein Conformation; Resveratrol; Tumor Cells, Cultured

2020
Resveratrol Suppresses Cross-Talk between Colorectal Cancer Cells and Stromal Cells in Multicellular Tumor Microenvironment: A Bridge between In Vitro and In Vivo Tumor Microenvironment Study.
    Molecules (Basel, Switzerland), 2020, Sep-18, Volume: 25, Issue:18

    Topics: Cell Communication; Cell Movement; Cell Survival; Colorectal Neoplasms; HCT116 Cells; Humans; Lymphotoxin-alpha; Neoplastic Stem Cells; NF-kappa B; Resveratrol; Signal Transduction; Sirtuin 1; Stromal Cells; Tumor Microenvironment

2020
Resveratrol induces human colorectal cancer cell apoptosis by activating the mitochondrial pathway via increasing reactive oxygen species.
    Molecular medicine reports, 2021, Volume: 23, Issue:3

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Colorectal Neoplasms; HCT116 Cells; Humans; Mitochondria; Neoplasm Proteins; Reactive Oxygen Species; Resveratrol; Signal Transduction

2021
New Hybrids Based on Curcumin and Resveratrol: Synthesis, Cytotoxicity and Antiproliferative Activity against Colorectal Cancer Cells.
    Molecules (Basel, Switzerland), 2021, May-01, Volume: 26, Issue:9

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; CHO Cells; Colorectal Neoplasms; Cricetinae; Cricetulus; Curcumin; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Resveratrol; Rhodamines

2021
Colorectal Adenocarcinoma Cell Culture in a Microfluidically Controlled Environment with a Static Molecular Gradient of Polyphenol.
    Molecules (Basel, Switzerland), 2021, May-27, Volume: 26, Issue:11

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Curcumin; Drug Screening Assays, Antitumor; Flavanones; Humans; Lab-On-A-Chip Devices; Microfluidic Analytical Techniques; Microfluidics; Neoplasms; Polyphenols; Resveratrol; Tumor Microenvironment

2021
The inhibitory effect of resveratrol on COX-2 expression in human colorectal cancer: a promising therapeutic strategy.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Humans; Resveratrol; RNA, Messenger; Stilbenes

2017
Application of open-access databases to determine functional connectivity between resveratrol-binding protein QR2 and colorectal carcinoma.
    In vitro cellular & developmental biology. Animal, 2017, Volume: 53, Issue:7

    Topics: Colorectal Neoplasms; Databases as Topic; Gene Expression Regulation, Neoplastic; Humans; Open Access Publishing; Quinone Reductases; Resveratrol; Stilbenes

2017
A novel resveratrol derivative selectively inhibits the proliferation of colorectal cancer cells with KRAS mutation.
    Molecular and cellular biochemistry, 2018, Volume: 442, Issue:1-2

    Topics: Cell Proliferation; Colorectal Neoplasms; Humans; MCF-7 Cells; Mutation; Proto-Oncogene Proteins p21(ras); Resveratrol; Signal Transduction; Stilbenes

2018
Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules.
    Nutrients, 2017, Sep-27, Volume: 9, Issue:10

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Adhesion Molecules; Cell Movement; Colorectal Neoplasms; Dose-Response Relationship, Drug; Focal Adhesion Kinase 1; Focal Adhesions; HCT116 Cells; Humans; Integrin beta1; Neoplasm Invasiveness; NF-kappa B; Protein Kinase Inhibitors; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors; Tumor Microenvironment

2017
Omega-3 PUFA Loaded in Resveratrol-Based Solid Lipid Nanoparticles: Physicochemical Properties and Antineoplastic Activities in Human Colorectal Cancer Cells In Vitro.
    International journal of molecular sciences, 2018, Feb-16, Volume: 19, Issue:2

    Topics: Animals; Antineoplastic Agents; Antioxidants; Cell Proliferation; Colorectal Neoplasms; Fatty Acids, Omega-3; HCT116 Cells; HT29 Cells; Humans; Nanoparticles; Rats; Resveratrol; Stearic Acids; Stilbenes

2018
Tristetraprolin activation by resveratrol inhibits the proliferation and metastasis of colorectal cancer cells.
    International journal of oncology, 2018, Volume: 53, Issue:3

    Topics: 3' Untranslated Regions; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Down-Regulation; E2F1 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Resveratrol; RNA Stability; RNA, Messenger; RNA, Small Interfering; Stilbenes; Tristetraprolin

2018
Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells.
    Nutrients, 2018, Jul-12, Volume: 10, Issue:7

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Fluorouracil; HCT116 Cells; Humans; Lymphotoxin-alpha; Neoplastic Stem Cells; Phenotype; Resveratrol; Signal Transduction; Stilbenes; Tumor Microenvironment

2018
Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers.
    Hormones & cancer, 2018, Volume: 9, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Humans; Mice; Mice, Nude; Polyglactin 910; Resveratrol; Thyroxine; Xenograft Model Antitumor Assays

2018
Phosphodiesterase 4B is an effective therapeutic target in colorectal cancer.
    Biochemical and biophysical research communications, 2019, 01-15, Volume: 508, Issue:3

    Topics: AMP-Activated Protein Kinases; Antineoplastic Agents; Azepines; Carcinogenesis; Cell Line, Tumor; Colorectal Neoplasms; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Humans; Phosphodiesterase 4 Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Resveratrol; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Triazoles

2019
Evidence that TNF-β induces proliferation in colorectal cancer cells and resveratrol can down-modulate it.
    Experimental biology and medicine (Maywood, N.J.), 2019, Volume: 244, Issue:1

    Topics: Cell Proliferation; Colorectal Neoplasms; Cytostatic Agents; Down-Regulation; HCT116 Cells; Humans; Lymphotoxin-alpha; NF-kappa B; Resveratrol

2019
Induction of the Epithelial-to-Mesenchymal Transition of Human Colorectal Cancer by Human TNF-β (Lymphotoxin) and its Reversal by Resveratrol.
    Nutrients, 2019, Mar-26, Volume: 11, Issue:3

    Topics: Biomarkers, Tumor; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Survival; Colorectal Neoplasms; Down-Regulation; Epithelial-Mesenchymal Transition; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Humans; Lymphotoxin-alpha; NF-kappa B; Receptors, Tumor Necrosis Factor; Resveratrol

2019
Pro-apoptotic genes as new targets for single and combinatorial treatments with resveratrol and curcumin in colorectal cancer.
    Food & function, 2019, Jun-19, Volume: 10, Issue:6

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Caco-2 Cells; Cell Line, Tumor; Colorectal Neoplasms; Curcumin; Drug Synergism; Humans; Resveratrol

2019
Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence.
    Science translational medicine, 2013, Oct-02, Volume: 5, Issue:205

    Topics: Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Glucuronides; Humans; Intracellular Space; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Resveratrol; Stilbenes; Sulfates

2013
OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro.
    Acta pharmacologica Sinica, 2014, Volume: 35, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Biomarkers; Caco-2 Cells; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Energy Metabolism; Glucose; HCT116 Cells; Humans; Resveratrol; Signal Transduction; Stilbenes; Thiazolidinediones

2014
Resveratrol-induced potentiation of the antitumor effects of oxaliplatin is accompanied by an altered cytokine profile of human monocyte-derived macrophages.
    Apoptosis : an international journal on programmed cell death, 2014, Volume: 19, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Blood Platelets; Caco-2 Cells; Coculture Techniques; Colorectal Neoplasms; Cytokines; Drug Synergism; Fibroblasts; Humans; Macrophages; Organoplatinum Compounds; Oxaliplatin; Resveratrol; Stilbenes; Transcriptome

2014
Inhibition of cancer derived cell lines proliferation by synthesized hydroxylated stilbenes and new ferrocenyl-stilbene analogs. Comparison with resveratrol.
    Molecules (Basel, Switzerland), 2014, Jun-11, Volume: 19, Issue:6

    Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Epithelial Cells; Ferrous Compounds; Hep G2 Cells; Humans; Intestinal Mucosa; Resveratrol; Stilbenes

2014
Resveratrol enhances mitomycin C-mediated suppression of human colorectal cancer cell proliferation by up-regulation of p21WAF1/CIP1.
    Anticancer research, 2014, Volume: 34, Issue:10

    Topics: alpha Karyopherins; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Mad2 Proteins; Mitomycin; Nuclear Proteins; Resveratrol; Stilbenes; Trans-Activators; Transcription Factors; Up-Regulation

2014
Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression.
    Carcinogenesis, 2014, Volume: 35, Issue:12

    Topics: Adenomatous Polyposis Coli Protein; Animals; Anticarcinogenic Agents; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Models, Animal; Female; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Knockout; Mutation; Proto-Oncogene Proteins p21(ras); Real-Time Polymerase Chain Reaction; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Tumor Cells, Cultured

2014
Augmented pentose phosphate pathway plays critical roles in colorectal carcinomas.
    Oncology, 2015, Volume: 88, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzoxazoles; Blotting, Western; Cell Line, Tumor; Colorectal Neoplasms; Female; Glucose; Glutathione Disulfide; Glycolysis; Humans; Japan; Lactic Acid; Mice; Mice, Nude; Pentose Phosphate Pathway; Plant Extracts; Pyrimidines; Receptors, Peptide; Resveratrol; Stilbenes; TOR Serine-Threonine Kinases; Transplantation, Heterologous; Treatment Outcome

2015
Modulatory role of resveratrol on cytotoxic activity of cisplatin, sensitization and modification of cisplatin resistance in colorectal cancer cells.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Antioxidants; Apoptosis; Carcinogenesis; Cell Cycle; Cisplatin; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; HCT116 Cells; Humans; Resveratrol; Stilbenes

2015
Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smads signaling pathway mediated Snail/E-cadherin expression.
    BMC cancer, 2015, Mar-05, Volume: 15

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cadherins; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Invasiveness; Promoter Regions, Genetic; Protein Binding; Resveratrol; Signal Transduction; Smad Proteins; Snail Family Transcription Factors; Stilbenes; Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays

2015
TCF4 Is a Molecular Target of Resveratrol in the Prevention of Colorectal Cancer.
    International journal of molecular sciences, 2015, May-07, Volume: 16, Issue:5

    Topics: Apoptosis; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Caco-2 Cells; Colorectal Neoplasms; Down-Regulation; Humans; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Resveratrol; Stilbenes; Transcription Factor 4; Transcription Factors

2015
Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-κB signaling and suppressing cAMP-responsive element transcriptional activity.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2015, Volume: 36, Issue:12

    Topics: AMP-Activated Protein Kinases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Colorectal Neoplasms; Cyclic AMP Response Element-Binding Protein; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; eIF-2 Kinase; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; I-kappa B Proteins; NF-KappaB Inhibitor alpha; Organoplatinum Compounds; Oxaliplatin; Resveratrol; Signal Transduction; Stilbenes; Transcriptional Activation

2015
Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice.
    Science translational medicine, 2015, Jul-29, Volume: 7, Issue:298

    Topics: Adenoma; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents, Phytogenic; Autophagy; Colorectal Neoplasms; Diet, High-Fat; Dose-Response Relationship, Drug; Humans; Mice; Resveratrol; Signal Transduction; Stilbenes; TOR Serine-Threonine Kinases

2015
Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer.
    Biochemical pharmacology, 2015, Nov-01, Volume: 98, Issue:1

    Topics: Alginates; Antimetabolites; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Culture Media; Drug Therapy, Combination; Epithelial Cells; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Intercellular Junctions; Mesenchymal Stem Cells; Resveratrol; Stilbenes; Up-Regulation

2015
Resveratrol elicits anti-colorectal cancer effect by activating miR-34c-KITLG in vitro and in vivo.
    BMC cancer, 2015, Dec-16, Volume: 15

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Organoplatinum Compounds; Oxaliplatin; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Xenograft Model Antitumor Assays

2015
Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells.
    Nutrients, 2016, Mar-05, Volume: 8, Issue:3

    Topics: Acetylation; Antineoplastic Agents; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; HCT116 Cells; Humans; Ki-67 Antigen; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Oligonucleotides, Antisense; Phosphorylation; Receptors, CXCR4; Resveratrol; Signal Transduction; Sirtuin 1; Stilbenes; Time Factors; Transcription Factor RelA; Transfection

2016
Response to comment on "Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice".
    Science translational medicine, 2016, 08-03, Volume: 8, Issue:350

    Topics: Adenoma; Animals; Antioxidants; Carcinogenesis; Chemoprevention; Colorectal Neoplasms; Diet, High-Fat; Female; Humans; Male; Mice; Resveratrol; Stilbenes

2016
Resveratrol Inhibits Proliferation, Invasion, and Epithelial-Mesenchymal Transition by Increasing miR-200c Expression in HCT-116 Colorectal Cancer Cells.
    Journal of cellular biochemistry, 2017, Volume: 118, Issue:6

    Topics: Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; MicroRNAs; Neoplasm Invasiveness; Resveratrol; Stilbenes; Up-Regulation

2017
Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells.
    Journal of agricultural and food chemistry, 2008, Jun-25, Volume: 56, Issue:12

    Topics: Anticarcinogenic Agents; Apoptosis; Caspase 3; Colorectal Neoplasms; DNA Fragmentation; HT29 Cells; Humans; Mitochondria; Reactive Oxygen Species; Resveratrol; Stilbenes

2008
Growth inhibition of human colon cancer cells by plant compounds.
    Clinical laboratory science : journal of the American Society for Medical Technology, 2008,Summer, Volume: 21, Issue:3

    Topics: Acrolein; Adenocarcinoma; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Piperidines; Plant Extracts; Resveratrol; Stilbenes

2008
Oral administration of resveratrol in suppression of pulmonary metastasis of BALB/c mice challenged with CT26 colorectal adenocarcinoma cells.
    Molecular nutrition & food research, 2010, Volume: 54, Issue:2

    Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Immunologic Factors; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Recurrence, Local; Neoplasm Transplantation; Random Allocation; Resveratrol; Stilbenes; Survival Analysis; Tumor Burden

2010
3,3',4,5,5'-Pentahydroxy-trans-stilbene, a resveratrol derivative, induces apoptosis in colorectal carcinoma cells via oxidative stress.
    European journal of pharmacology, 2010, Jul-10, Volume: 637, Issue:1-3

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Colorectal Neoplasms; Cytoplasm; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Glutathione; HT29 Cells; Humans; Nucleosomes; Oxidative Stress; Poly(ADP-ribose) Polymerases; Resveratrol; Stilbenes; Tumor Cells, Cultured; Up-Regulation

2010
Resveratrol-induced apoptosis is mediated by early growth response-1, Krüppel-like factor 4, and activating transcription factor 3.
    Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:1

    Topics: Activating Transcription Factor 3; Anticarcinogenic Agents; Apoptosis; Base Sequence; Binding Sites; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Colorectal Neoplasms; Early Growth Response Protein 1; Electrophoretic Mobility Shift Assay; Humans; Immunoenzyme Techniques; Immunoprecipitation; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Luciferases; Molecular Sequence Data; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stilbenes; Transcriptional Activation

2011
[Resveratrol acts by modulating miRNAs].
    Medecine sciences : M/S, 2011, Volume: 27, Issue:1

    Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; Cytokines; Gene Expression Regulation; Humans; Inflammation; Inflammation Mediators; MicroRNAs; Models, Biological; Neoplasm Proteins; Prostaglandins; Proto-Oncogene Proteins c-jun; Reactive Oxygen Species; Resveratrol; RNA, Neoplasm; Stilbenes

2011
Resveratrol in combination with other dietary polyphenols concomitantly enhances antiproliferation and UGT1A1 induction in Caco-2 cells.
    Life sciences, 2011, Jun-06, Volume: 88, Issue:23-24

    Topics: Anticarcinogenic Agents; Caco-2 Cells; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Curcumin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Enzyme Induction; Flavonoids; Glucuronides; Glucuronosyltransferase; Humans; Inhibitory Concentration 50; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes

2011
The dietary compounds resveratrol and genistein induce activating transcription factor 3 while suppressing inhibitor of DNA binding/differentiation-1.
    Journal of medicinal food, 2011, Volume: 14, Issue:6

    Topics: Activating Transcription Factor 3; Cell Line, Tumor; Colorectal Neoplasms; Down-Regulation; Genistein; Humans; Inhibitor of Differentiation Protein 1; Resveratrol; Stilbenes; Up-Regulation

2011
5-fluorouracil increases the chemopreventive potentials of resveratrol through DNA damage and MAPK signaling pathway in human colorectal cancer cells.
    Oncology research, 2011, Volume: 19, Issue:7

    Topics: Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle; Cell Movement; Cell Survival; Colorectal Neoplasms; DNA Damage; Fluorouracil; HCT116 Cells; Humans; MAP Kinase Signaling System; Resveratrol; Stilbenes

2011
Low-dose dietary resveratrol has differential effects on colorectal tumorigenesis in adiponectin knockout and wild-type mice.
    Nutrition and cancer, 2011, Volume: 63, Issue:8

    Topics: Adipocytes; Adiponectin; Animals; Azoxymethane; Caco-2 Cells; Cell Transformation, Neoplastic; Colorectal Neoplasms; Dextran Sulfate; Dietary Fats; Dose-Response Relationship, Drug; Female; Humans; Insulin; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Resveratrol; Sex Factors; Stilbenes; Weight Gain

2011
Metabonomic variations associated with AOM-induced precancerous colorectal lesions and resveratrol treatment.
    Journal of proteome research, 2012, Jun-01, Volume: 11, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colorectal Neoplasms; Male; Metabolome; Precancerous Conditions; Rats; Rats, Wistar; Resveratrol; Stilbenes

2012
Resveratrol, a chemopreventive agent, disrupts the cell cycle control of human SW480 colorectal tumor cells.
    International journal of molecular medicine, 2002, Volume: 10, Issue:2

    Topics: Adenocarcinoma; Anticarcinogenic Agents; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Colorectal Neoplasms; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; DNA Replication; Enzyme Induction; Flow Cytometry; Gene Expression Regulation, Neoplastic; Growth Inhibitors; Humans; Neoplasm Proteins; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Resveratrol; S Phase; Stilbenes; Tumor Cells, Cultured

2002
Role of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells.
    BMC cancer, 2002, Oct-17, Volume: 2

    Topics: Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma; Cell Survival; Colorectal Neoplasms; Humans; Membrane Potentials; Mitochondria; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Stilbenes; Tumor Cells, Cultured

2002
Pharmacokinetics in mice and growth-inhibitory properties of the putative cancer chemopreventive agent resveratrol and the synthetic analogue trans 3,4,5,4'-tetramethoxystilbene.
    British journal of cancer, 2004, Feb-09, Volume: 90, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Chemoprevention; Colorectal Neoplasms; Drug Design; Hydroxylation; Isomerism; Mice; Resveratrol; Stilbenes; Tissue Distribution

2004
The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3).
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:5

    Topics: Activating Transcription Factor 3; Allyl Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Chromans; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Disulfides; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Male; Mice; Mice, Nude; Microarray Analysis; Neoplasm Invasiveness; Resveratrol; RNA, Messenger; Stilbenes; Sulindac; Thiazolidinediones; Transcription Factors; Transplantation, Heterologous; Troglitazone; Up-Regulation

2005
Bax and Bak are the critical complementary effectors of colorectal cancer cell apoptosis by chemopreventive resveratrol.
    Anti-cancer drugs, 2006, Volume: 17, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Line, Tumor; Colorectal Neoplasms; Humans; Resveratrol; Signal Transduction; Stilbenes

2006
Apoptosis in a tissue-like culture model of human colorectal adenoma cells.
    Tissue & cell, 2006, Volume: 38, Issue:3

    Topics: Adenoma; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Culture Techniques; Collagen; Colorectal Neoplasms; Drug Evaluation, Preclinical; Models, Biological; Quercetin; Resveratrol; Stilbenes; Tumor Cells, Cultured

2006
Resveratrol induces cell death in colorectal cancer cells by a novel pathway involving lysosomal cathepsin D.
    Carcinogenesis, 2007, Volume: 28, Issue:5

    Topics: Caspase Inhibitors; Cathepsin D; Cathepsin L; Cathepsins; Cell Death; Cell Line; Colorectal Neoplasms; Cysteine Endopeptidases; Cytochromes c; Cytosol; Dose-Response Relationship, Drug; HT29 Cells; Humans; Lysosomes; Resveratrol; Stilbenes; Time Factors

2007
"Soybean" in a Haystack? pinpointing an anti-cancer effect.
    Journal of the National Cancer Institute, 1999, Oct-06, Volume: 91, Issue:19

    Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Colorectal Neoplasms; Garlic; Glycine max; Humans; Neoplasms; Phytotherapy; Plants, Medicinal; Resveratrol; Selenium; Stilbenes; Tea

1999
Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21(CIP) expression.
    Carcinogenesis, 2000, Volume: 21, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Azoxymethane; bcl-2-Associated X Protein; Carcinogens; Cell Division; Colon; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Growth Inhibitors; Intestinal Mucosa; Male; Precancerous Conditions; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344; Rectum; Resveratrol; Stilbenes

2000